SNU475 Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
External Link https://depmap.org/portal/cell_line/ACH-000422
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Genes

716 gene knockdowns changing fitness of SNU475 relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
ESX1 ESX homeobox 1 20.1391
MADD MAP-kinase activating death domain 14.8247
LMNB2 lamin B2 14.3601
CREB3L1 cAMP responsive element binding protein 3-like 1 14.1677
AUTS2 autism susceptibility candidate 2 11.084
TWIST2 twist family bHLH transcription factor 2 10.8326
AXIN2 axin 2 9.5158
RSBN1L round spermatid basic protein 1-like 9.30272
TMEM115 transmembrane protein 115 9.07579
EME1 essential meiotic structure-specific endonuclease 1 9.07019
SCAMP4 secretory carrier membrane protein 4 8.96493
HARBI1 harbinger transposase derived 1 8.69685
PHF21A PHD finger protein 21A 8.48607
NIPAL1 NIPA-like domain containing 1 8.27372
ADPGK ADP-dependent glucokinase 7.99464
ASB4 ankyrin repeat and SOCS box containing 4 7.78054
APCDD1 adenomatosis polyposis coli down-regulated 1 7.70619
LECT1 leukocyte cell derived chemotaxin 1 7.60701
SYCE2 synaptonemal complex central element protein 2 7.34328
DDB2 damage-specific DNA binding protein 2, 48kDa 7.19003
C12ORF66 chromosome 12 open reading frame 66 6.83209
CRY2 cryptochrome circadian clock 2 6.81485
XPA xeroderma pigmentosum, complementation group A 6.81005
HYAL2 hyaluronoglucosaminidase 2 6.8001
CCDC103 coiled-coil domain containing 103 6.73912
S1PR5 sphingosine-1-phosphate receptor 5 6.60443
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 6.57236
ZNF408 zinc finger protein 408 6.55539
LARGE2 LARGE xylosyl- and glucuronyltransferase 2 6.45797
GSTP1 glutathione S-transferase pi 1 6.42925
SS18 synovial sarcoma translocation, chromosome 18 6.31694
ATF7IP activating transcription factor 7 interacting protein 6.28672
LHFPL4 lipoma HMGIC fusion partner-like 4 6.27596
MDK midkine (neurite growth-promoting factor 2) 6.24996
ACP2 acid phosphatase 2, lysosomal 6.13249
NPM2 nucleophosmin/nucleoplasmin 2 6.0068
SNAI1 snail family zinc finger 1 5.87693
GUSB glucuronidase, beta 5.81845
CHRM4 cholinergic receptor, muscarinic 4 5.79342
SSH3 slingshot protein phosphatase 3 5.71889
KREMEN2 kringle containing transmembrane protein 2 5.68673
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 5.66105
TMEM248 transmembrane protein 248 5.58387
GPR149 G protein-coupled receptor 149 5.56291
ZNF503 zinc finger protein 503 5.47236
TRAM2 translocation associated membrane protein 2 5.45559
LGALS3 lectin, galactoside-binding, soluble, 3 5.45367
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 5.42877
HIST1H3B histone cluster 1, H3b 5.39331
VASH1 vasohibin 1 5.31229
KIAA0556 KIAA0556 5.30719
TIMP1 TIMP metallopeptidase inhibitor 1 5.2829
OR8J3 olfactory receptor, family 8, subfamily J, member 3 5.27802
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 5.24578
F2 coagulation factor II (thrombin) 5.21712
MLXIPL MLX interacting protein-like 5.21329
GID4 GID complex subunit 4 5.20291
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 5.14947
FBXL12 F-box and leucine-rich repeat protein 12 5.14158
AUNIP aurora kinase A and ninein interacting protein 5.13015
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.07871
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 5.0741
TXK TXK tyrosine kinase 5.07279
SCGB3A1 secretoglobin, family 3A, member 1 5.05635
ACTL10 actin-like 10 5.02903
STYXL2 serine/threonine/tyrosine interacting like 2 5.02078
PDGFRB platelet-derived growth factor receptor, beta polypeptide 5.0163
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 5.007
XPO7 exportin 7 4.94668
CTXN3 cortexin 3 4.94396
SUCO SUN domain containing ossification factor 4.88908
YPEL4 yippee-like 4 (Drosophila) 4.87996
HOXB3 homeobox B3 4.86463
RHEBL1 Ras homolog enriched in brain like 1 4.8602
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 4.81609
PRRT1 proline-rich transmembrane protein 1 4.81417
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 4.76521
MTMR11 myotubularin related protein 11 4.74902
CATSPERD catsper channel auxiliary subunit delta 4.65579
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 4.65411
TBX10 T-box 10 4.63052
PTX3 pentraxin 3, long 4.6126
ASPH aspartate beta-hydroxylase 4.60138
CLEC11A C-type lectin domain family 11, member A 4.59506
KRT77 keratin 77, type II 4.59009
STOML2 stomatin (EPB72)-like 2 4.58686
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 4.57468
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 4.4782
VWCE von Willebrand factor C and EGF domains 4.4747
RUFY3 RUN and FYVE domain containing 3 4.45453
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 4.41438
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 4.36595
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 4.35631
FLNC filamin C, gamma 4.34812
ERI1 exoribonuclease 1 4.33526
DAND5 DAN domain family member 5, BMP antagonist 4.31117
KCTD7 potassium channel tetramerization domain containing 7 4.3082
TIPE1 TNF alpha induced protein 8 like 1 4.29944
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 4.28279
AREG amphiregulin 4.27888
FBXL15 F-box and leucine-rich repeat protein 15 4.25895
PODNL1 podocan-like 1 4.2471
USP33 ubiquitin specific peptidase 33 4.22321
COL6A3 collagen, type VI, alpha 3 4.21164
MATK megakaryocyte-associated tyrosine kinase 4.21085
RAB33B RAB33B, member RAS oncogene family 4.1828
OR5H14 olfactory receptor, family 5, subfamily H, member 14 4.17996
STX8 syntaxin 8 4.16835
IQCF5 IQ motif containing F5 4.16597
C21ORF62 chromosome 21 open reading frame 62 4.16131
SP100 SP100 nuclear antigen 4.15891
MRGPRX4 MAS-related GPR, member X4 4.14968
PTRH2 peptidyl-tRNA hydrolase 2 4.13261
CUL4B cullin 4B 4.09091
ALX4 ALX homeobox 4 4.08945
OSR1 odd-skipped related transciption factor 1 4.08912
SIKE1 suppressor of IKBKE 1 4.07521
MESDC1 mesoderm development candidate 1 4.04382
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 4.04082
MREG melanoregulin 4.01517
HSPA4L heat shock 70kDa protein 4-like 4.01099
UBAP2 ubiquitin associated protein 2 3.9852
SLC45A4 solute carrier family 45, member 4 3.98469
ZDHHC12 zinc finger, DHHC-type containing 12 3.98196
ZMYND10 zinc finger, MYND-type containing 10 3.98166
ABLIM1 actin binding LIM protein 1 3.97742
HOXA4 homeobox A4 3.97542
PHGR1 proline/histidine/glycine-rich 1 3.97525
SHCBP1 SHC SH2-domain binding protein 1 3.96644
IQCC IQ motif containing C 3.96067
GSX2 GS homeobox 2 3.95907
TPST1 tyrosylprotein sulfotransferase 1 3.93732
CLDN3 claudin 3 3.93511
C12ORF73 chromosome 12 open reading frame 73 3.92882
WBP2NL WBP2 N-terminal like 3.91019
SLC22A18 solute carrier family 22, member 18 3.88664
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 3.85652
HSD11B1L hydroxysteroid (11-beta) dehydrogenase 1-like 3.85158
SYAP1 synapse associated protein 1 3.84581
TSPAN1 tetraspanin 1 3.84277
HBD hemoglobin, delta 3.82873
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 3.81917
TXLNB taxilin beta 3.81594
PLEKHA5 pleckstrin homology domain containing, family A member 5 3.80924
NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit 3.80703
UNC45B unc-45 homolog B (C. elegans) 3.80139
BCL3 B-cell CLL/lymphoma 3 3.79896
TNRC18 trinucleotide repeat containing 18 3.79736
CNOT10 CCR4-NOT transcription complex, subunit 10 3.79628
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 3.7935
MTFR1L mitochondrial fission regulator 1-like 3.78433
OAZ1 ornithine decarboxylase antizyme 1 3.77318
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 3.76771
TTC39C tetratricopeptide repeat domain 39C 3.76577
CREB3L2 cAMP responsive element binding protein 3-like 2 3.75386
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 3.74531
ZNF12 zinc finger protein 12 3.74421
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 3.73523
TRAM1 translocation associated membrane protein 1 3.73148
ZNF565 zinc finger protein 565 3.73024
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 3.72413
DVL2 dishevelled segment polarity protein 2 3.72318
SMAD7 SMAD family member 7 3.70685
PLA1A phospholipase A1 member A 3.69845
NADK NAD kinase 3.69835
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 3.68608
H1-10 H1.10 linker histone 3.68067
XPO4 exportin 4 3.68054
FAM86B2 family with sequence similarity 86, member B2 3.67577
TP53I13 tumor protein p53 inducible protein 13 3.67558
IFRD2 interferon-related developmental regulator 2 3.66383
SFTPA2 surfactant protein A2 3.65739
PARP4 poly (ADP-ribose) polymerase family, member 4 3.65168
SERINC5 serine incorporator 5 3.65072
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 3.64223
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 3.63489
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 3.62917
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 3.62335
ASF1A anti-silencing function 1A histone chaperone 3.61737
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.61426
CLPTM1L CLPTM1-like 3.61315
PEX11B peroxisomal biogenesis factor 11 beta 3.60575
C3ORF80 chromosome 3 open reading frame 80 3.60571
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 3.60262
RTN1 reticulon 1 3.60123
IWS1 IWS1 homolog (S. cerevisiae) 3.60079
MSC musculin 3.59496
MARK1 MAP/microtubule affinity-regulating kinase 1 3.59392
IFIH1 interferon induced with helicase C domain 1 3.58654
BEND6 BEN domain containing 6 3.5807
SELENOH selenoprotein H 3.56726
SMIM18 small integral membrane protein 18 3.56574
PLIN5 perilipin 5 3.56119
LRRC59 leucine rich repeat containing 59 3.55977
KIAA0825 KIAA0825 3.55728
BTBD2 BTB (POZ) domain containing 2 3.55187
C9ORF9 chromosome 9 open reading frame 9 3.54965
WDR6 WD repeat domain 6 3.53511
CLDN20 claudin 20 3.53477
EBI3 Epstein-Barr virus induced 3 3.51803
OR8I2 olfactory receptor, family 8, subfamily I, member 2 3.51253
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 3.50561
RUFY2 RUN and FYVE domain containing 2 3.50357
RSRP1 arginine/serine-rich protein 1 3.50231
CHAD chondroadherin 3.49852
METTL20 methyltransferase like 20 3.49626
PATL2 protein associated with topoisomerase II homolog 2 (yeast) 3.48082
SCAI suppressor of cancer cell invasion 3.47913
ZEB1 zinc finger E-box binding homeobox 1 3.47162
KLK2 kallikrein-related peptidase 2 3.46721
PCDHGC5 protocadherin gamma subfamily C, 5 3.4636
CARMIL1 capping protein regulator and myosin 1 linker 1 3.46331
LACRT lacritin 3.45936
CCDC17 coiled-coil domain containing 17 3.44877
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 3.44616
LBR lamin B receptor 3.43094
CNTF ciliary neurotrophic factor 3.43057
SNAI2 snail family zinc finger 2 3.42256
RAG1 recombination activating gene 1 3.41752
PRDX5 peroxiredoxin 5 3.41738
MUS81 MUS81 structure-specific endonuclease subunit 3.413
CNOT12 CCR4-NOT transcription complex subunit 12 3.40257
PCSK1 proprotein convertase subtilisin/kexin type 1 3.39872
NONO non-POU domain containing, octamer-binding 3.39188
CTNND1 catenin (cadherin-associated protein), delta 1 3.34761
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 3.34143
GPBP1 GC-rich promoter binding protein 1 3.33509
TMPO thymopoietin 3.33455
CLEC3B C-type lectin domain family 3, member B 3.32641
CNGB1 cyclic nucleotide gated channel beta 1 3.32423
C21ORF140 chromosome 21 open reading frame 140 3.32341
RIMS1 regulating synaptic membrane exocytosis 1 3.30288
THEM6 thioesterase superfamily member 6 3.30207
SAMD14 sterile alpha motif domain containing 14 3.28608
ATG13 autophagy related 13 3.26146
EDA ectodysplasin A 3.25786
ZSCAN10 zinc finger and SCAN domain containing 10 3.25303
GUCA1B guanylate cyclase activator 1B (retina) 3.25293
CD300LG CD300 molecule-like family member g 3.24414
GPR1 G protein-coupled receptor 1 3.2337
LASP1 LIM and SH3 protein 1 3.23207
PSPC1 paraspeckle component 1 3.22994
APCDD1L adenomatosis polyposis coli down-regulated 1-like 3.2299
PCGF2 polycomb group ring finger 2 3.22903
FBXO22 F-box protein 22 3.22719
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 3.20931
HCRT hypocretin (orexin) neuropeptide precursor 3.20897
ZYG11A zyg-11 family member A, cell cycle regulator 3.20659
BHLHE40 basic helix-loop-helix family, member e40 3.19715
RGS4 regulator of G-protein signaling 4 3.17911
TGOLN2 trans-golgi network protein 2 3.17893
TEX19 testis expressed 19 3.16888
OTUD1 OTU deubiquitinase 1 3.15645
A4GNT alpha-1,4-N-acetylglucosaminyltransferase 3.1536
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3.15075
RNF170 ring finger protein 170 3.14825
HAGH hydroxyacylglutathione hydrolase 3.14283
TAPT1 transmembrane anterior posterior transformation 1 3.13259
QRICH1 glutamine-rich 1 3.12691
EPHX4 epoxide hydrolase 4 3.12532
RAB6B RAB6B, member RAS oncogene family 3.12499
ZNF584 zinc finger protein 584 3.12111
TIGD2 tigger transposable element derived 2 3.11969
ING2 inhibitor of growth family, member 2 3.11627
NUSAP1 nucleolar and spindle associated protein 1 3.11442
ARL8A ADP-ribosylation factor-like 8A 3.11343
TTC22 tetratricopeptide repeat domain 22 3.11214
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 3.10028
SP5 Sp5 transcription factor 3.07878
OTOA otoancorin 3.07875
CDKN2AIP CDKN2A interacting protein 3.06815
DGKZ diacylglycerol kinase, zeta 3.06699
ZNF768 zinc finger protein 768 3.06618
KRT81 keratin 81, type II 3.06325
ZNF92 zinc finger protein 92 3.06223
CYB5R3 cytochrome b5 reductase 3 3.05545
EPHA5 EPH receptor A5 3.05042
ATAD3C ATPase family, AAA domain containing 3C 3.04679
ZSWIM1 zinc finger, SWIM-type containing 1 3.04162
ZNF554 zinc finger protein 554 3.03557
CREG2 cellular repressor of E1A-stimulated genes 2 3.03462
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 3.0312
NBL1 neuroblastoma 1, DAN family BMP antagonist 3.02746
SLC31A2 solute carrier family 31 (copper transporter), member 2 3.02217
FNDC8 fibronectin type III domain containing 8 3.02014
MAGEF1 melanoma antigen family F1 3.01877
SPATS1 spermatogenesis associated, serine-rich 1 3.01841
ARHGAP1 Rho GTPase activating protein 1 3.01005
ATP5IF1 ATP synthase inhibitory factor subunit 1 3.00594
C16ORF89 chromosome 16 open reading frame 89 3.00517
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 3.00207
TNNC1 troponin C type 1 (slow) 3.00125
LY86 lymphocyte antigen 86 2.99687
IL32 interleukin 32 2.99106
PMP22 peripheral myelin protein 22 2.98751
ZCCHC24 zinc finger, CCHC domain containing 24 2.9871
DAGLB diacylglycerol lipase, beta 2.98658
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) 2.9854
APOL5 apolipoprotein L, 5 2.98432
NMRAL1 NmrA-like family domain containing 1 2.98379
MAST1 microtubule associated serine/threonine kinase 1 2.97688
EGFL6 EGF-like-domain, multiple 6 2.97415
TPCN1 two pore segment channel 1 2.97295
PRR4 proline rich 4 (lacrimal) 2.9712
ADPRS ADP-ribosylserine hydrolase 2.96334
DUSP1 dual specificity phosphatase 1 2.95837
CCDC74B coiled-coil domain containing 74B 2.95758
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 2.94742
TBC1D4 TBC1 domain family, member 4 2.94682
AGRP agouti related neuropeptide 2.9448
BCDIN3D BCDIN3 domain containing 2.9422
IFT20 intraflagellar transport 20 2.93501
TMCO6 transmembrane and coiled-coil domains 6 2.93203
NAGLU N-acetylglucosaminidase, alpha 2.93019
SURF4 surfeit 4 2.92294
TCL1A T-cell leukemia/lymphoma 1A 2.91988
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.91742
LIMCH1 LIM and calponin homology domains 1 2.91282
AQP11 aquaporin 11 2.90212
SLC39A5 solute carrier family 39 (zinc transporter), member 5 2.89607
CCDC185 coiled-coil domain containing 185 2.895
GTF3C6 general transcription factor IIIC, polypeptide 6, alpha 35kDa 2.89048
KCNK15 potassium channel, two pore domain subfamily K, member 15 2.87544
OR9G1 olfactory receptor, family 9, subfamily G, member 1 2.87513
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 2.87205
VCPKMT valosin containing protein lysine (K) methyltransferase 2.87004
GTSF1 gametocyte specific factor 1 2.86936
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 2.86047
GPATCH3 G patch domain containing 3 2.86006
PLN phospholamban 2.85113
TMEM54 transmembrane protein 54 2.85051
SRSF9 serine/arginine-rich splicing factor 9 2.84903
URGCP upregulator of cell proliferation 2.84597
C3ORF52 chromosome 3 open reading frame 52 2.83927
PAQR4 progestin and adipoQ receptor family member IV 2.8347
SYT16 synaptotagmin XVI 2.83456
VAT1L vesicle amine transport 1-like 2.82955
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2.82848
CFDP1 craniofacial development protein 1 2.82422
RIDA reactive intermediate imine deaminase A homolog 2.82267
PEX16 peroxisomal biogenesis factor 16 2.81537
SPNS2 spinster homolog 2 (Drosophila) 2.81126
GPR143 G protein-coupled receptor 143 2.80731
TMEM14C transmembrane protein 14C 2.80244
RPTN repetin 2.80119
MDC1 mediator of DNA-damage checkpoint 1 2.79907
OR8D4 olfactory receptor, family 8, subfamily D, member 4 2.78898
CCR1 chemokine (C-C motif) receptor 1 2.78647
APC adenomatous polyposis coli 2.78611
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 2.78495
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.78451
PLAC9 placenta-specific 9 2.7844
HOXC12 homeobox C12 2.77999
ANKRD13B ankyrin repeat domain 13B 2.77215
POMT2 protein-O-mannosyltransferase 2 2.76626
SUGCT succinyl-CoA:glutarate-CoA transferase 2.76406
WBP4 WW domain binding protein 4 2.76168
MYCBPAP MYCBP associated protein 2.75934
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.75728
LRRC43 leucine rich repeat containing 43 2.75432
PADI3 peptidyl arginine deiminase, type III 2.74659
TNNT1 troponin T type 1 (skeletal, slow) 2.7391
SMIM24 small integral membrane protein 24 2.73897
ACSF2 acyl-CoA synthetase family member 2 2.73835
IER5L immediate early response 5-like 2.73413
WRAP53 WD repeat containing, antisense to TP53 2.73129
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.72615
SNX18 sorting nexin 18 2.72295
ANKRD54 ankyrin repeat domain 54 2.72142
TBC1D2B TBC1 domain family, member 2B 2.72129
OR5B12 olfactory receptor, family 5, subfamily B, member 12 2.70536
ZDHHC4 zinc finger, DHHC-type containing 4 2.69791
VASH2 vasohibin 2 2.69225
SNX32 sorting nexin 32 2.69182
GCH1 GTP cyclohydrolase 1 2.68935
TTC30A tetratricopeptide repeat domain 30A 2.68563
QKI QKI, KH domain containing, RNA binding 2.68267
RBMS1 RNA binding motif, single stranded interacting protein 1 2.67689
HACL1 2-hydroxyacyl-CoA lyase 1 2.6711
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.66598
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 2.66515
RAB39B RAB39B, member RAS oncogene family 2.66221
ISM2 isthmin 2 2.65766
SARAF store-operated calcium entry-associated regulatory factor 2.64953
GLS2 glutaminase 2 (liver, mitochondrial) 2.64648
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.64489
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.64398
ZDHHC23 zinc finger, DHHC-type containing 23 2.64271
SH2D3A SH2 domain containing 3A 2.63932
PI16 peptidase inhibitor 16 2.63925
TAC1 tachykinin, precursor 1 2.63732
CES3 carboxylesterase 3 2.63421
TSPAN6 tetraspanin 6 2.63265
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.62933
C2ORF72 chromosome 2 open reading frame 72 2.6249
TCF12 transcription factor 12 2.62367
ALKBH3 alkB, alkylation repair homolog 3 (E. coli) 2.6222
TRIM42 tripartite motif containing 42 2.61935
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 2.61456
PPP1R36 protein phosphatase 1, regulatory subunit 36 2.61456
IER3IP1 immediate early response 3 interacting protein 1 2.61276
PPT2 palmitoyl-protein thioesterase 2 2.60439
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 2.60049
NME1 NME/NM23 nucleoside diphosphate kinase 1 2.59676
MTMR3 myotubularin related protein 3 2.59377
SPATA31E1 SPATA31 subfamily E, member 1 2.58878
ZNF646 zinc finger protein 646 2.58805
SCAF8 SR-related CTD-associated factor 8 2.57971
SPEF2 sperm flagellar 2 2.5751
POPDC2 popeye domain containing 2 2.57422
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.57276
ARHGAP12 Rho GTPase activating protein 12 2.57166
KIF2C kinesin family member 2C 2.56712
SPAG9 sperm associated antigen 9 2.56711
SRL sarcalumenin 2.5669
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 2.56374
GTPBP2 GTP binding protein 2 2.56072
TST thiosulfate sulfurtransferase (rhodanese) 2.55922
RFX8 RFX family member 8, lacking RFX DNA binding domain 2.55847
CBFB core-binding factor, beta subunit 2.5561
NFE2L2 nuclear factor, erythroid 2-like 2 2.55574
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.55545
TSLP thymic stromal lymphopoietin 2.55438
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 2.54244
XYLT2 xylosyltransferase II 2.53454
RWDD3 RWD domain containing 3 2.52196
ABHD11 abhydrolase domain containing 11 2.5163
FAM124B family with sequence similarity 124B 2.51355
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.51318
RBM27 RNA binding motif protein 27 2.51058
LONP2 lon peptidase 2, peroxisomal 2.50954
HAGHL hydroxyacylglutathione hydrolase-like 2.50669
CCM2L cerebral cavernous malformation 2-like 2.5029
CEP43 centrosomal protein 43 2.50193
RSPRY1 ring finger and SPRY domain containing 1 2.50182
ANKDD1A ankyrin repeat and death domain containing 1A 2.50138
SPHK1 sphingosine kinase 1 2.50127
ACOXL acyl-CoA oxidase-like 2.49467
PRSS35 protease, serine, 35 2.49373
FAM222B family with sequence similarity 222, member B 2.49247
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.49176
OR51E1 olfactory receptor, family 51, subfamily E, member 1 2.49103
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 2.49083
ADIRF adipogenesis regulatory factor 2.4899
C7ORF31 chromosome 7 open reading frame 31 2.48978
XKR8 XK, Kell blood group complex subunit-related family, member 8 2.48875
DHRS7B dehydrogenase/reductase (SDR family) member 7B 2.4887
SOS1 son of sevenless homolog 1 (Drosophila) 2.4884
PHF19 PHD finger protein 19 2.48744
ZNF622 zinc finger protein 622 2.48637
ART1 ADP-ribosyltransferase 1 2.48437
FAM92B family with sequence similarity 92, member B 2.48198
PPT1 palmitoyl-protein thioesterase 1 2.48166
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like 2.47932
CHURC1 churchill domain containing 1 2.47646
SCG5 secretogranin V 2.47445
CDH24 cadherin 24, type 2 2.47321
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 2.46859
COPRS coordinator of PRMT5, differentiation stimulator 2.4668
ZNF138 zinc finger protein 138 2.46605
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.46221
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 2.4603
TAC4 tachykinin 4 (hemokinin) 2.45949
KLHDC4 kelch domain containing 4 2.45873
CD47 CD47 molecule 2.45831
LIMS2 LIM and senescent cell antigen-like domains 2 2.45128
NBN nibrin 2.44616
EXT2 exostosin glycosyltransferase 2 2.43704
HOXC8 homeobox C8 2.43656
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.43466
AMER1 APC membrane recruitment protein 1 2.43232
RAB8B RAB8B, member RAS oncogene family 2.43136
RBBP7 retinoblastoma binding protein 7 2.43048
RAP1GAP RAP1 GTPase activating protein 2.42991
RSAD1 radical S-adenosyl methionine domain containing 1 2.42538
SEMG2 semenogelin II 2.4243
CYB561 cytochrome b561 2.42242
ARID1A AT rich interactive domain 1A (SWI-like) 2.42057
LRP4 low density lipoprotein receptor-related protein 4 2.41917
MIB1 mindbomb E3 ubiquitin protein ligase 1 2.41876
TIGIT T cell immunoreceptor with Ig and ITIM domains 2.41524
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.41503
TAPBP TAP binding protein (tapasin) 2.41398
MFAP4 microfibrillar-associated protein 4 2.41187
PHC2 polyhomeotic homolog 2 (Drosophila) 2.41117
PTCHD4 patched domain containing 4 2.40996
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.40993
ZSCAN23 zinc finger and SCAN domain containing 23 2.40741
ITGA1 integrin, alpha 1 2.40592
PPIB peptidylprolyl isomerase B (cyclophilin B) 2.40499
UBXN1 UBX domain protein 1 2.40348
CDCA3 cell division cycle associated 3 2.40291
OR6C3 olfactory receptor, family 6, subfamily C, member 3 2.40179
UBE2A ubiquitin-conjugating enzyme E2A 2.39886
COL20A1 collagen, type XX, alpha 1 2.39498
SERTAD4 SERTA domain containing 4 2.39484
MOG myelin oligodendrocyte glycoprotein 2.39056
SRRM2 serine/arginine repetitive matrix 2 2.39036
GCSAM germinal center-associated, signaling and motility 2.38766
LCN2 lipocalin 2 2.3873
C11ORF87 chromosome 11 open reading frame 87 2.38089
CENPX centromere protein X 2.38072
ZXDC ZXD family zinc finger C 2.37477
TOMM70 translocase of outer mitochondrial membrane 70 2.37377
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 2.37172
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 2.36658
DEFB136 defensin, beta 136 2.36482
CABP5 calcium binding protein 5 2.36457
TMEM151B transmembrane protein 151B 2.35986
ZMYM4 zinc finger, MYM-type 4 2.35735
CCL5 chemokine (C-C motif) ligand 5 2.35458
ICAM1 intercellular adhesion molecule 1 2.35421
KIAA1549L KIAA1549-like 2.35405
TMEM216 transmembrane protein 216 2.35163
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2.34747
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 2.34646
RAB21 RAB21, member RAS oncogene family 2.34177
ZNF680 zinc finger protein 680 2.3411
SEC62 SEC62 homolog (S. cerevisiae) 2.34029
IGFBP5 insulin-like growth factor binding protein 5 2.33712
POU3F4 POU class 3 homeobox 4 2.3358
TBX18 T-box 18 2.33345
ALKBH7 alkB, alkylation repair homolog 7 (E. coli) 2.33339
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 2.33148
GSC goosecoid homeobox 2.33045
LOXL2 lysyl oxidase-like 2 2.32599
NOTUM notum pectinacetylesterase homolog (Drosophila) 2.3226
TSPAN32 tetraspanin 32 2.32175
LIMK1 LIM domain kinase 1 2.32026
EXT1 exostosin glycosyltransferase 1 2.31985
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 2.31898
ZNF836 zinc finger protein 836 2.31805
CEMIP cell migration inducing protein, hyaluronan binding 2.31799
RNF111 ring finger protein 111 2.31421
PROM2 prominin 2 2.31411
MB myoglobin 2.31284
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 2.3117
NAF1 nuclear assembly factor 1 ribonucleoprotein 2.30445
FAHD2A fumarylacetoacetate hydrolase domain containing 2A 2.30208
PARD3B par-3 family cell polarity regulator beta 2.30182
KPNA4 karyopherin alpha 4 (importin alpha 3) 2.29436
LYPD6 LY6/PLAUR domain containing 6 2.29407
MIPEP mitochondrial intermediate peptidase 2.29269
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.29202
TET2 tet methylcytosine dioxygenase 2 2.28871
NHLH1 nescient helix loop helix 1 2.2872
GOLGA4 golgin A4 2.2851
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 2.28489
ORAI3 ORAI calcium release-activated calcium modulator 3 2.28433
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 2.28396
CCDC177 coiled-coil domain containing 177 2.28286
FCRL2 Fc receptor-like 2 2.28232
OGA O-GlcNAcase 2.27771
VSTM2A V-set and transmembrane domain containing 2A 2.27662
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.27222
METTL12 methyltransferase like 12 2.27128
PRKCH protein kinase C, eta 2.26803
HAP1 huntingtin-associated protein 1 2.26685
OR6S1 olfactory receptor, family 6, subfamily S, member 1 2.26548
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 2.26385
SBK1 SH3 domain binding kinase 1 2.26384
FGF19 fibroblast growth factor 19 2.26024
FGFR1 fibroblast growth factor receptor 1 2.25863
GLRX3 glutaredoxin 3 2.25762
EEF2K eukaryotic elongation factor 2 kinase 2.25736
ING4 inhibitor of growth family, member 4 2.25733
FSIP1 fibrous sheath interacting protein 1 2.25635
TMEM59 transmembrane protein 59 2.25499
NUTM2G NUT family member 2G 2.23906
SZRD1 SUZ RNA binding domain containing 1 2.2387
ACER3 alkaline ceramidase 3 2.23842
NAV3 neuron navigator 3 2.23748
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 2.2353
CCL3 chemokine (C-C motif) ligand 3 2.23159
MOSPD3 motile sperm domain containing 3 2.23043
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 2.2302
XIRP1 xin actin binding repeat containing 1 2.2278
CNIH3 cornichon family AMPA receptor auxiliary protein 3 2.22612
MPLKIP M-phase specific PLK1 interacting protein 2.22503
BCAN brevican 2.22353
FKBP1A FK506 binding protein 1A, 12kDa 2.22273
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 2.22077
SELENOO selenoprotein O 2.21956
PAIP2B poly(A) binding protein interacting protein 2B 2.21933
BICC1 BicC family RNA binding protein 1 2.21901
BBS2 Bardet-Biedl syndrome 2 2.21505
SUFU suppressor of fused homolog (Drosophila) 2.21383
DTX2 deltex 2, E3 ubiquitin ligase 2.21187
ZNF771 zinc finger protein 771 2.21029
SNX33 sorting nexin 33 2.21001
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.2095
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2.20889
BAD BCL2-associated agonist of cell death 2.2046
MS4A8 membrane-spanning 4-domains, subfamily A, member 8 2.2037
DBF4B DBF4 zinc finger B 2.20316
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.20237
ATXN2L ataxin 2-like 2.20113
IGLON5 IgLON family member 5 2.20086
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 2.20031
KIAA0100 KIAA0100 2.19601
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 2.19429
ADCY6 adenylate cyclase 6 2.19364
CA7 carbonic anhydrase VII 2.19326
TMEM205 transmembrane protein 205 2.19048
PSAP prosaposin 2.18401
NUP188 nucleoporin 188kDa 2.18114
CLIP2 CAP-GLY domain containing linker protein 2 2.17837
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.17748
RRAD Ras-related associated with diabetes 2.17713
ZFP36L2 ZFP36 ring finger protein-like 2 2.17678
ERCC8 excision repair cross-complementation group 8 2.1756
OR5AK2 olfactory receptor, family 5, subfamily AK, member 2 2.1744
HILPDA hypoxia inducible lipid droplet-associated 2.17313
LIN7C lin-7 homolog C (C. elegans) 2.17178
THAP9 THAP domain containing 9 2.17174
PPIF peptidylprolyl isomerase F 2.16594
SETD5 SET domain containing 5 2.16401
HACD2 3-hydroxyacyl-CoA dehydratase 2 2.15519
IL27 interleukin 27 2.1546
INO80E INO80 complex subunit E 2.15236
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.15024
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.14963
CISD1 CDGSH iron sulfur domain 1 2.14643
FAM57B family with sequence similarity 57, member B 2.14569
HMGA2 high mobility group AT-hook 2 2.14528
ERO1B endoplasmic reticulum oxidoreductase 1 beta 2.14356
BSPRY B-box and SPRY domain containing 2.14274
FANCM Fanconi anemia, complementation group M 2.1424
GAS1 growth arrest-specific 1 2.1415
MAGEA6 melanoma antigen family A6 2.14083
PDS5A PDS5 cohesin associated factor A 2.13941
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 2.13383
NUTM2A NUT family member 2A 2.13361
ZFP36L1 ZFP36 ring finger protein-like 1 2.13037
TPRG1L tumor protein p63 regulated 1-like 2.12737
FGF4 fibroblast growth factor 4 2.12511
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.12435
TARBP2 TAR (HIV-1) RNA binding protein 2 2.12261
PCCB propionyl CoA carboxylase, beta polypeptide 2.12248
C2ORF68 chromosome 2 open reading frame 68 2.12059
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 2.12033
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 2.11995
POF1B premature ovarian failure, 1B 2.11929
TMEM106A transmembrane protein 106A 2.1132
OIT3 oncoprotein induced transcript 3 2.11163
RAD54L RAD54-like (S. cerevisiae) 2.10861
CISD3 CDGSH iron sulfur domain 3 2.10845
TLCD1 TLC domain containing 1 2.10568
IZUMO4 IZUMO family member 4 2.10542
GPR174 G protein-coupled receptor 174 2.10408
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.10043
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 2.09948
DSCC1 DNA replication and sister chromatid cohesion 1 2.09943
SELENOI selenoprotein I 2.09942
LBX1 ladybird homeobox 1 2.09923
FRG2B FSHD region gene 2 family, member B 2.09543
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.09413
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 2.09377
KHDC1L KH homology domain containing 1-like 2.09321
TERF2IP telomeric repeat binding factor 2, interacting protein 2.09237
RXRA retinoid X receptor, alpha 2.09097
C17ORF105 chromosome 17 open reading frame 105 2.08866
NEGR1 neuronal growth regulator 1 2.08781
DNASE2 deoxyribonuclease II, lysosomal 2.0874
SNX3 sorting nexin 3 2.08639
NT5C 5', 3'-nucleotidase, cytosolic 2.08328
STAG2 stromal antigen 2 2.08221
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 2.08213
SPTBN1 spectrin, beta, non-erythrocytic 1 2.08039
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 2.0802
OR2L2 olfactory receptor, family 2, subfamily L, member 2 2.07964
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 2.07586
WDR38 WD repeat domain 38 2.07427
RREB1 ras responsive element binding protein 1 2.07088
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3 2.06995
RBM15 RNA binding motif protein 15 2.0667
RTL8C retrotransposon Gag like 8C 2.06538
THUMPD1 THUMP domain containing 1 2.06307
TRHDE thyrotropin-releasing hormone degrading enzyme 2.06122
C17ORF58 chromosome 17 open reading frame 58 2.06024
DCAF10 DDB1 and CUL4 associated factor 10 2.05999
PDCL phosducin-like 2.05997
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.05667
FAF1 Fas (TNFRSF6) associated factor 1 2.05587
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 2.05437
FKBP2 FK506 binding protein 2, 13kDa 2.05436
ENDOV endonuclease V 2.05322
VAX2 ventral anterior homeobox 2 2.05199
PGBDF plakoglobin binding and degradation factor 2.05064
TMBIM6 transmembrane BAX inhibitor motif containing 6 2.0501
GPC1 glypican 1 2.04755
C17ORF75 chromosome 17 open reading frame 75 2.04534
ANAPC13 anaphase promoting complex subunit 13 2.04356
POGZ pogo transposable element with ZNF domain 2.0432
UNKL unkempt family zinc finger-like 2.04027
HDAC10 histone deacetylase 10 2.03777
SYCP2L synaptonemal complex protein 2-like 2.03583
FAM117A family with sequence similarity 117, member A 2.03526
LHX5 LIM homeobox 5 2.03526
LMTK2 lemur tyrosine kinase 2 2.03515
LPPR3 lipid phosphate phosphatase-related protein type 3 2.03052
RSC1A1 regulatory solute carrier protein, family 1, member 1 2.02573
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.02296
EPHB1 EPH receptor B1 2.02218
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.01968
EIF3L eukaryotic translation initiation factor 3, subunit L 2.01952
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 2.01686
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 2.01376
PNOC prepronociceptin 2.01136
ALKBH5 AlkB family member 5, RNA demethylase 2.00839
N4BP2 NEDD4 binding protein 2 2.00433
IPO4 importin 4 2.00413
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 2.00328
TMEM134 transmembrane protein 134 2.00197
MAPK1 mitogen-activated protein kinase 1 2.00152
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.00106