| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | sterol O-acyltransferase 2|Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8435) |
| External Link | https://ncbi.nlm.nih.gov/gene/8435 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the SOAT2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KYNU | kynureninase | 0.0150129 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0124695 |
| ZNF395 | zinc finger protein 395 | 0.012421 |
| RGCC | regulator of cell cycle | 0.0123511 |
| THBD | thrombomodulin | 0.0120666 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0118063 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0112153 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0107908 |
| S100A7 | S100 calcium binding protein A7 | 0.0107562 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0105481 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0103974 |
| TMEM45A | transmembrane protein 45A | 0.0102502 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.0102437 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0101746 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.010141 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.0101357 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.0101201 |
| MOCOS | molybdenum cofactor sulfurase | 0.0100995 |
| RNF167 | ring finger protein 167 | 0.0100454 |
| KRT17 | keratin 17, type I | 0.00997239 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00989007 |
| HNMT | histamine N-methyltransferase | 0.00988056 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00973246 |
| CHN1 | chimerin 1 | 0.00965283 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00954356 |
| IL1RN | interleukin 1 receptor antagonist | 0.00949072 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00944134 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00921567 |
| CTSH | cathepsin H | 0.00919678 |
| ABLIM1 | actin binding LIM protein 1 | 0.00910049 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00909128 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00905031 |
| PIP | prolactin-induced protein | 0.00889693 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00889287 |
| CD93 | CD93 molecule | 0.00879106 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00876471 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0087214 |
| FCGBP | Fc fragment of IgG binding protein | 0.00871464 |
| SHTN1 | shootin 1 | 0.00866694 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00859299 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00858198 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00857797 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00851111 |
| MCL1 | myeloid cell leukemia 1 | 0.00849852 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00849371 |
| DAXX | death-domain associated protein | 0.0084794 |
| CD86 | CD86 molecule | 0.00845342 |
| GPC3 | glypican 3 | 0.00843363 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00841321 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00839655 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00839452 |
| SARAF | store-operated calcium entry-associated regulatory factor | 0.00837501 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00835527 |
| S100A2 | S100 calcium binding protein A2 | 0.00831154 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00830821 |
| XIC | X chromosome inactivation center | 0.008287 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00827622 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.0082604 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00817498 |
| METRN | meteorin, glial cell differentiation regulator | 0.00801204 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00799138 |
| DSP | desmoplakin | 0.00797597 |
| IFNGR1 | interferon gamma receptor 1 | 0.00797175 |
| LAMC2 | laminin, gamma 2 | 0.00796662 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00787258 |
| TOX3 | TOX high mobility group box family member 3 | 0.00782733 |
| ITGAV | integrin, alpha V | 0.00779784 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00778396 |
| C3 | complement component 3 | 0.00773027 |
| SORD | sorbitol dehydrogenase | 0.00769782 |
| KRT5 | keratin 5, type II | 0.00769345 |
| CD163 | CD163 molecule | 0.00765351 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00755767 |
| IRF6 | interferon regulatory factor 6 | 0.00753831 |
| IQCG | IQ motif containing G | 0.00749572 |
| CADM1 | cell adhesion molecule 1 | 0.00746976 |
| RBM34 | RNA binding motif protein 34 | 0.00746242 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.00742665 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00741607 |
| INHBB | inhibin, beta B | 0.00740305 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00740078 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00739054 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00737545 |
| RNASET2 | ribonuclease T2 | 0.00736892 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00733871 |
| TBX3 | T-box 3 | 0.00732591 |
| TMEM204 | transmembrane protein 204 | 0.0073084 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00726941 |
| GIMAP5 | GTPase, IMAP family member 5 | 0.00722469 |
| VWF | von Willebrand factor | 0.0071827 |
| TAGLN2 | transgelin 2 | 0.00716373 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00714514 |
| CTSS | cathepsin S | 0.0071362 |
| MMD | monocyte to macrophage differentiation-associated | 0.00713585 |
| EGR2 | early growth response 2 | 0.0071193 |
| CSTA | cystatin A (stefin A) | 0.00711198 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00711136 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00709101 |
| CLDN8 | claudin 8 | 0.00702893 |
| GLUL | glutamate-ammonia ligase | 0.00700123 |
| AK4 | adenylate kinase 4 | 0.00699625 |
| KRT6B | keratin 6B, type II | 0.006932 |
| RRAGA | Ras-related GTP binding A | 0.00688799 |
| GPX2 | glutathione peroxidase 2 | 0.00688757 |
| LY96 | lymphocyte antigen 96 | 0.00687096 |
| FMO5 | flavin containing monooxygenase 5 | 0.00683547 |
| COG5 | component of oligomeric golgi complex 5 | 0.00682187 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00681955 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00681806 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.00678655 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00677669 |
| CD209 | CD209 molecule | 0.00676815 |
| CLTB | clathrin, light chain B | 0.00673061 |
| SP110 | SP110 nuclear body protein | 0.00669395 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00667727 |
| SPRR3 | small proline-rich protein 3 | 0.00667352 |
| EVI2A | ecotropic viral integration site 2A | 0.00667106 |
| AREG | amphiregulin | 0.0066453 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00664367 |
| AIM2 | absent in melanoma 2 | 0.00662468 |
| NGRN | neugrin, neurite outgrowth associated | 0.00661324 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00659324 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00655776 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00653611 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00653483 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00652672 |
| SERINC5 | serine incorporator 5 | 0.00650218 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 0.00648615 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00648211 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00647549 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00646504 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00639633 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00637663 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00637377 |
| CSF1R | colony stimulating factor 1 receptor | 0.00635462 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00633836 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00631181 |
| CHI3L2 | chitinase 3-like 2 | 0.00630155 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00629747 |
| SLA | Src-like-adaptor | 0.00628265 |
| BTG2 | BTG family, member 2 | 0.00626509 |
| BID | BH3 interacting domain death agonist | 0.00626199 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00623186 |
| ANOS1 | anosmin 1 | 0.00622698 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.0062227 |
| CD1B | CD1b molecule | 0.00621486 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00619348 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00618301 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00617882 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00617853 |
| CLDN7 | claudin 7 | 0.00616632 |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.00616173 |
| GSDME | gasdermin E | 0.00614961 |
| RIN2 | Ras and Rab interactor 2 | 0.00614624 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00614023 |
| C3AR1 | complement component 3a receptor 1 | 0.00613996 |
| TNC | tenascin C | 0.00613063 |
| TXNL1 | thioredoxin-like 1 | 0.00611291 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0061028 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00608072 |
| PLEK2 | pleckstrin 2 | 0.00607931 |
| CH25H | cholesterol 25-hydroxylase | 0.00607589 |
| CTSC | cathepsin C | 0.00607503 |
| COPA | coatomer protein complex, subunit alpha | 0.00607073 |
| LAMB3 | laminin, beta 3 | 0.00606597 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00605982 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00604449 |
| PEG3 | paternally expressed 3 | 0.00599265 |
| PTHLH | parathyroid hormone-like hormone | 0.00596301 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00595894 |
| RAB25 | RAB25, member RAS oncogene family | 0.00595695 |
| NCOA4 | nuclear receptor coactivator 4 | 0.00595666 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0059298 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00592904 |
| HAT1 | histone acetyltransferase 1 | 0.005925 |
| COPS7A | COP9 signalosome subunit 7A | 0.00592225 |
| SNX13 | sorting nexin 13 | 0.00592185 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00592028 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00591812 |
| ATOX1 | antioxidant 1 copper chaperone | 0.00591091 |
| TRIM29 | tripartite motif containing 29 | 0.00590218 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.005898 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00589506 |
| DCTN4 | dynactin 4 (p62) | 0.00589232 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00587952 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00585866 |
| EVL | Enah/Vasp-like | 0.00585632 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.00584329 |
| KRT23 | keratin 23, type I | 0.00584113 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00582736 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.00580371 |
| CPE | carboxypeptidase E | 0.00579555 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00579498 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00576608 |
| RBM47 | RNA binding motif protein 47 | 0.00575555 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00574056 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.00573967 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00573896 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.0057367 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.00573037 |
| DEFB1 | defensin, beta 1 | 0.00572912 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.0057115 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00570477 |
| GPM6B | glycoprotein M6B | 0.0056542 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00565273 |
| CD1A | CD1a molecule | 0.00565075 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00564689 |
| EPCAM | epithelial cell adhesion molecule | 0.00561956 |
| KLK10 | kallikrein-related peptidase 10 | 0.00561376 |
| CCDC6 | coiled-coil domain containing 6 | 0.00560754 |
| SKP1 | S-phase kinase-associated protein 1 | 0.00560304 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00560013 |
| CD14 | CD14 molecule | 0.00559385 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00559078 |
| A2M | alpha-2-macroglobulin | 0.00558352 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.00556553 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00556181 |
| CST6 | cystatin E/M | 0.00555916 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00555463 |
| TRIM14 | tripartite motif containing 14 | 0.00555316 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0055436 |
| CD1E | CD1e molecule | 0.00552671 |
| STC1 | stanniocalcin 1 | 0.00552521 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00552098 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0055072 |
| CD1C | CD1c molecule | 0.00549113 |
| AQP9 | aquaporin 9 | 0.00549088 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00548237 |
| SMAD2 | SMAD family member 2 | 0.00547922 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00547874 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | 0.00547245 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00546927 |
| FYB1 | FYN binding protein 1 | 0.00546235 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00545145 |
| FABP7 | fatty acid binding protein 7, brain | 0.00542995 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00542188 |
| RAB20 | RAB20, member RAS oncogene family | 0.00541929 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00541868 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00541834 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00541242 |
| AFP | alpha-fetoprotein | 0.00540008 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.0053939 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.00539176 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00539054 |
| EFNA1 | ephrin-A1 | 0.00538697 |
| GAA | glucosidase, alpha; acid | 0.00537791 |
| LY86 | lymphocyte antigen 86 | 0.00536299 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00533932 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00533195 |
| TMC5 | transmembrane channel-like 5 | 0.00532748 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.022057 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0153264 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0128944 |
| TYMS | thymidylate synthetase | -0.0124009 |
| FHL1 | four and a half LIM domains 1 | -0.0120602 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.011865 |
| G0S2 | G0/G1 switch 2 | -0.0114629 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0110624 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.01072 |
| AMOTL2 | angiomotin like 2 | -0.0104621 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00982639 |
| FSTL1 | follistatin-like 1 | -0.00981797 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00978419 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00965279 |
| TSPAN12 | tetraspanin 12 | -0.00962175 |
| NOTCH1 | notch 1 | -0.00959423 |
| BEX1 | brain expressed, X-linked 1 | -0.00957348 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00952346 |
| XYLT1 | xylosyltransferase I | -0.00944921 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00923683 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00911113 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00894595 |
| CRYAB | crystallin, alpha B | -0.00893985 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00883421 |
| CTSD | cathepsin D | -0.00868816 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00856508 |
| KAZN | kazrin, periplakin interacting protein | -0.0085186 |
| S100A4 | S100 calcium binding protein A4 | -0.00848076 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00847276 |
| CTH | cystathionine gamma-lyase | -0.00846294 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00837532 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00831545 |
| SMAD7 | SMAD family member 7 | -0.00830767 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00830758 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00825979 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00825629 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00821282 |
| LEPR | leptin receptor | -0.00820065 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0081395 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00801148 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00799891 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -0.00794997 |
| TUBB6 | tubulin, beta 6 class V | -0.00794646 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00792592 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.007884 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00785446 |
| SIX1 | SIX homeobox 1 | -0.00771367 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00769476 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00768696 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00764279 |
| HBD | hemoglobin, delta | -0.00760711 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00756872 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00756636 |
| CLEC11A | C-type lectin domain family 11, member A | -0.0075574 |
| ELANE | elastase, neutrophil expressed | -0.00755603 |
| PROM1 | prominin 1 | -0.00755393 |
| GPX3 | glutathione peroxidase 3 | -0.00750932 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00749077 |
| PLK2 | polo-like kinase 2 | -0.00745613 |
| AOC1 | amine oxidase, copper containing 1 | -0.00744316 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00741087 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00729166 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00725817 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00725393 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00724805 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00717786 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00713499 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00712885 |
| PITX3 | paired-like homeodomain 3 | -0.00710894 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00709522 |
| NPTX2 | neuronal pentraxin II | -0.00708639 |
| HMGB1 | high mobility group box 1 | -0.00703025 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00702792 |
| PENK | proenkephalin | -0.00701984 |
| MOK | MOK protein kinase | -0.00701033 |
| RTN2 | reticulon 2 | -0.00696433 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0069232 |
| CRY1 | cryptochrome circadian clock 1 | -0.00690183 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00686675 |
| ZNF329 | zinc finger protein 329 | -0.00685348 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -0.00683162 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00679321 |
| STK38 | serine/threonine kinase 38 | -0.00675138 |
| CA3 | carbonic anhydrase III | -0.0067067 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00670238 |
| CCND2 | cyclin D2 | -0.00666598 |
| POSTN | periostin, osteoblast specific factor | -0.00665333 |
| STK10 | serine/threonine kinase 10 | -0.00664583 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | -0.0066419 |
| ING3 | inhibitor of growth family, member 3 | -0.00662616 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.00656817 |
| PCP4 | Purkinje cell protein 4 | -0.00655969 |
| NOTCH2NL | notch 2 N-terminal like | -0.00654839 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00654062 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00653565 |
| CTSG | cathepsin G | -0.00653317 |
| BGN | biglycan | -0.00653266 |
| NID2 | nidogen 2 (osteonidogen) | -0.00650867 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00650854 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00649997 |
| CCN2 | cellular communication network factor 2 | -0.0064901 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.00646667 |
| H2AX | H2A.X variant histone | -0.00646448 |
| GDF15 | growth differentiation factor 15 | -0.00644461 |
| PFKM | phosphofructokinase, muscle | -0.00643619 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) | -0.00643303 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.00643029 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00642804 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -0.00642098 |
| RCAN2 | regulator of calcineurin 2 | -0.00638623 |
| PDZK1 | PDZ domain containing 1 | -0.00638249 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00633154 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -0.0063288 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00632278 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00628617 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -0.00627568 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00627105 |
| CHRDL1 | chordin-like 1 | -0.00626166 |
| EMX2 | empty spiracles homeobox 2 | -0.00624857 |
| APOD | apolipoprotein D | -0.00624632 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.0062307 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | -0.00622796 |
| GNAS | GNAS complex locus | -0.00620654 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00618965 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00618146 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0061772 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00616173 |
| ASPA | aspartoacylase | -0.00613592 |
| PXDN | peroxidasin | -0.00609947 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | -0.0060957 |
| MGLL | monoglyceride lipase | -0.00609159 |
| EHD3 | EH-domain containing 3 | -0.00608576 |
| PCNA | proliferating cell nuclear antigen | -0.00607629 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00604951 |
| PLIN2 | perilipin 2 | -0.00604779 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00604133 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00604045 |
| CCNA2 | cyclin A2 | -0.00603998 |
| CDC20 | cell division cycle 20 | -0.00603607 |
| CRHBP | corticotropin releasing hormone binding protein | -0.00603034 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0060159 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -0.00599623 |
| H2AZ1 | H2A.Z variant histone 1 | -0.00598363 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00597573 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00595542 |
| AK1 | adenylate kinase 1 | -0.00595134 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00591077 |
| BDNF | brain-derived neurotrophic factor | -0.00590623 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00589392 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00587876 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme | -0.00585482 |
| CDK11A | cyclin-dependent kinase 11A | -0.00583586 |
| FZD2 | frizzled class receptor 2 | -0.00583238 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00583233 |
| CTSL | cathepsin L | -0.00582983 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00582915 |
| NNMT | nicotinamide N-methyltransferase | -0.00582113 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.00578852 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 | -0.00575615 |
| RIDA | reactive intermediate imine deaminase A homolog | -0.00575052 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00574635 |
| RCAN1 | regulator of calcineurin 1 | -0.00573189 |
| AMH | anti-Mullerian hormone | -0.00571165 |
| IRX5 | iroquois homeobox 5 | -0.00570024 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00569949 |
| LMNB2 | lamin B2 | -0.00568804 |
| CKM | creatine kinase, muscle | -0.00568797 |
| TAGLN | transgelin | -0.00568499 |
| FGF9 | fibroblast growth factor 9 | -0.0056594 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.0056328 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00563111 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00562381 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00559627 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00558413 |
| MYOT | myotilin | -0.00558272 |
| CCND1 | cyclin D1 | -0.00557728 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00557248 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.0055696 |
| DNM1 | dynamin 1 | -0.00554114 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | -0.00552548 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00551933 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00551549 |
| ASS1 | argininosuccinate synthase 1 | -0.00550021 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00549997 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00547771 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00547592 |
| ZNF415 | zinc finger protein 415 | -0.00547552 |
| BMP2 | bone morphogenetic protein 2 | -0.00546228 |
| ZNF22 | zinc finger protein 22 | -0.00546212 |
| KLHL41 | kelch-like family member 41 | -0.0054448 |
| MT1E | metallothionein 1E | -0.00543434 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00543247 |
| PCLAF | PCNA clamp associated factor | -0.00542517 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -0.00542313 |
| SRGN | serglycin | -0.00541222 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00540646 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00539492 |
| PRDX2 | peroxiredoxin 2 | -0.00537121 |
| NAV3 | neuron navigator 3 | -0.00536226 |
| PMPCA | peptidase (mitochondrial processing) alpha | -0.00536061 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00535134 |
| TPBG | trophoblast glycoprotein | -0.00534785 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.00534366 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00533986 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00529174 |
| INSIG1 | insulin induced gene 1 | -0.00527504 |
| STC2 | stanniocalcin 2 | -0.00526679 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00525873 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00525353 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00525319 |
| NPY | neuropeptide Y | -0.00525141 |
| PRKCB | protein kinase C, beta | -0.00524752 |
| ZNF83 | zinc finger protein 83 | -0.00522446 |
| ZNF91 | zinc finger protein 91 | -0.00520649 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00520536 |
| CD200 | CD200 molecule | -0.00520288 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00519848 |
| CTPS1 | CTP synthase 1 | -0.00518992 |
| ADCY9 | adenylate cyclase 9 | -0.00518672 |
| OAT | ornithine aminotransferase | -0.00518543 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00518193 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.00517808 |
| PHGDH | phosphoglycerate dehydrogenase | -0.00517563 |
| AURKB | aurora kinase B | -0.0051572 |
| FASN | fatty acid synthase | -0.00515499 |
| TSPYL5 | TSPY-like 5 | -0.00515256 |
| TSPAN7 | tetraspanin 7 | -0.00515087 |
| TRIM28 | tripartite motif containing 28 | -0.00514239 |
| MUC1 | mucin 1, cell surface associated | -0.00514174 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00514164 |
| SSH1 | slingshot protein phosphatase 1 | -0.00514034 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00513474 |
| UBE2M | ubiquitin-conjugating enzyme E2M | -0.00513162 |
| EPS8L2 | EPS8-like 2 | -0.0051299 |
| TMEM176B | transmembrane protein 176B | -0.00512332 |
| HRASLS | HRAS-like suppressor | -0.00512092 |
| FADS1 | fatty acid desaturase 1 | -0.00512067 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | -0.00512061 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00511937 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00510976 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.00510759 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00510631 |
| SRRT | serrate, RNA effector molecule | -0.00509774 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00509544 |
| MAGED1 | melanoma antigen family D1 | -0.00508932 |
| MB | myoglobin | -0.00508342 |
| FOXO4 | forkhead box O4 | -0.00507384 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00506647 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.00505025 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00501743 |
