SOAT2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description sterol O-acyltransferase 2|Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8435)
External Link http://www.ncbi.nlm.nih.gov/gene/8435
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Genes

2 interacting proteins for SOAT2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
BAG3 BCL2-associated athanogene 3
E2F4 E2F transcription factor 4, p107/p130-binding