| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | suppressor of cytokine signaling 2|This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] (NCBI Entrez Gene Database, 8835) |
| External Link | https://ncbi.nlm.nih.gov/gene/8835 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the SOCS2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | 0.00974912 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.00961043 |
| CA2 | carbonic anhydrase II | 0.00947075 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00911499 |
| HP | haptoglobin | 0.00861379 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00825183 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00800899 |
| MAP7 | microtubule-associated protein 7 | 0.0075466 |
| EPHB2 | EPH receptor B2 | 0.00733635 |
| IDE | insulin-degrading enzyme | 0.0072851 |
| KLK6 | kallikrein-related peptidase 6 | 0.00720733 |
| MYO5C | myosin VC | 0.00719436 |
| LXN | latexin | 0.0071919 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00714838 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00697607 |
| ELANE | elastase, neutrophil expressed | 0.00694943 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00693967 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00671977 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00670086 |
| ACTN1 | actinin, alpha 1 | 0.0066509 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00662375 |
| PRDX2 | peroxiredoxin 2 | 0.00660223 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00637877 |
| CPE | carboxypeptidase E | 0.0063057 |
| CD93 | CD93 molecule | 0.00627508 |
| PODXL | podocalyxin-like | 0.00626996 |
| FGF13 | fibroblast growth factor 13 | 0.00620254 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00614858 |
| ABLIM1 | actin binding LIM protein 1 | 0.00612161 |
| PTK2 | protein tyrosine kinase 2 | 0.00605916 |
| IL18 | interleukin 18 | 0.0060394 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00602022 |
| HOXA5 | homeobox A5 | 0.00600161 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00592335 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00587503 |
| SNX11 | sorting nexin 11 | 0.00583285 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00577561 |
| MYRF | myelin regulatory factor | 0.00575698 |
| RPA3 | replication protein A3, 14kDa | 0.00574911 |
| NNT | nicotinamide nucleotide transhydrogenase | 0.00573163 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00572855 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.0057269 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00568478 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00564025 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00561405 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00560713 |
| PDGFD | platelet derived growth factor D | 0.00556505 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00553829 |
| TLK2 | tousled-like kinase 2 | 0.00543555 |
| CDC20 | cell division cycle 20 | 0.00539272 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00536511 |
| ANXA3 | annexin A3 | 0.00534087 |
| BEX1 | brain expressed, X-linked 1 | 0.00531235 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00530893 |
| GLUL | glutamate-ammonia ligase | 0.0053065 |
| TPD52 | tumor protein D52 | 0.00530465 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00530078 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00525686 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00524418 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00523687 |
| ITGB4 | integrin, beta 4 | 0.00520989 |
| PIR | pirin (iron-binding nuclear protein) | 0.00519466 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0051766 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00517424 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00514707 |
| MGST2 | microsomal glutathione S-transferase 2 | 0.00514654 |
| CP | ceruloplasmin (ferroxidase) | 0.00512504 |
| SETD5 | SET domain containing 5 | 0.00510962 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00510911 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00506419 |
| ZNF395 | zinc finger protein 395 | 0.00505943 |
| ACTB | actin, beta | 0.00498235 |
| ADIRF | adipogenesis regulatory factor | 0.00495975 |
| PGC | progastricsin (pepsinogen C) | 0.00493102 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00490718 |
| PRTN3 | proteinase 3 | 0.00490342 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00487403 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00486878 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0048664 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00484505 |
| RHOA | ras homolog family member A | 0.00483745 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00483371 |
| CTSG | cathepsin G | 0.00482633 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00479716 |
| CBX1 | chromobox homolog 1 | 0.00479514 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00478081 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00476132 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00475178 |
| PURA | purine-rich element binding protein A | 0.00474431 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00472569 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00471994 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00471841 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00470297 |
| CRTAP | cartilage associated protein | 0.00470134 |
| CD38 | CD38 molecule | 0.00469001 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00465917 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00465825 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00463717 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00462754 |
| INSR | insulin receptor | 0.00462362 |
| GPC3 | glypican 3 | 0.00462305 |
| MALL | mal, T-cell differentiation protein-like | 0.00462124 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00459799 |
| BLVRB | biliverdin reductase B | 0.00459532 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00459328 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00459167 |
| MSLN | mesothelin | 0.00458541 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.00457723 |
| KLK8 | kallikrein-related peptidase 8 | 0.00457619 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00454111 |
| CFD | complement factor D (adipsin) | 0.00452755 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00452646 |
| MRPL12 | mitochondrial ribosomal protein L12 | 0.00451373 |
| CD14 | CD14 molecule | 0.00449981 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.00447905 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00447474 |
| KLK7 | kallikrein-related peptidase 7 | 0.00447053 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00445942 |
| ACKR3 | atypical chemokine receptor 3 | 0.00445668 |
| MSH6 | mutS homolog 6 | 0.00444382 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00444141 |
| CCNB2 | cyclin B2 | 0.00443341 |
| S100A12 | S100 calcium binding protein A12 | 0.00442972 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00442394 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00441708 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 0.0044165 |
| PRKCH | protein kinase C, eta | 0.00440518 |
| CA12 | carbonic anhydrase XII | 0.00439283 |
| S100A9 | S100 calcium binding protein A9 | 0.0043646 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00436439 |
| EMCN | endomucin | 0.00436152 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.00435916 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00435537 |
| TGM2 | transglutaminase 2 | 0.00434355 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00433867 |
| OLFML2A | olfactomedin-like 2A | 0.00433201 |
| CFH | complement factor H | 0.00432417 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.0043215 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00432145 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00431263 |
| SQLE | squalene epoxidase | 0.00426958 |
| MICALL1 | MICAL-like 1 | 0.00426325 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00425008 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00423539 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00423453 |
| MYOF | myoferlin | 0.0042344 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00423114 |
| ADM | adrenomedullin | 0.00423007 |
| GATA6 | GATA binding protein 6 | 0.0042276 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00421367 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00421337 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.0042129 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00421259 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00420086 |
| PCLAF | PCNA clamp associated factor | 0.00419256 |
| TEX2 | testis expressed 2 | 0.00419197 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | 0.00419014 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00417678 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00417672 |
| MFAP5 | microfibrillar associated protein 5 | 0.00417204 |
| VLDLR | very low density lipoprotein receptor | 0.00417202 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00416879 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00416687 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00416315 |
| KAZN | kazrin, periplakin interacting protein | 0.00416167 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00416161 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00415701 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00415003 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic | 0.00413378 |
| CD163 | CD163 molecule | 0.00413152 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00413095 |
| TAGLN | transgelin | 0.00413084 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00412869 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00412716 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.00411141 |
| CDA | cytidine deaminase | 0.00410717 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00410306 |
| GNPAT | glyceronephosphate O-acyltransferase | 0.0040755 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00406927 |
| FNBP1 | formin binding protein 1 | 0.00405389 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.0040538 |
| TCTA | T-cell leukemia translocation altered | 0.00405184 |
| KLK11 | kallikrein-related peptidase 11 | 0.00405022 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00404908 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00404647 |
| DIXDC1 | DIX domain containing 1 | 0.00404418 |
| SST | somatostatin | 0.00403857 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00402004 |
| MPO | myeloperoxidase | 0.00401554 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00400888 |
| CUX1 | cut-like homeobox 1 | 0.00400366 |
| BFAR | bifunctional apoptosis regulator | 0.00400145 |
| PXDN | peroxidasin | 0.00399146 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00398533 |
| CAV2 | caveolin 2 | 0.0039773 |
| ASRGL1 | asparaginase like 1 | 0.00397355 |
| GPX3 | glutathione peroxidase 3 | 0.00396395 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00396111 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00395956 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00395948 |
| ITGA6 | integrin, alpha 6 | 0.00395618 |
| MTF2 | metal response element binding transcription factor 2 | 0.00393223 |
| MED13 | mediator complex subunit 13 | 0.00392899 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00392504 |
| NSF | N-ethylmaleimide-sensitive factor | 0.00391806 |
| TMEM135 | transmembrane protein 135 | 0.00391559 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00391378 |
| ACTN4 | actinin, alpha 4 | 0.00391071 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00390157 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00389907 |
| STOM | stomatin | 0.00389768 |
| USP22 | ubiquitin specific peptidase 22 | 0.00389127 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00388755 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.00388325 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00388165 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00386805 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00386774 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00386644 |
| C1S | complement component 1, s subcomponent | 0.00385605 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00383222 |
| TRIB2 | tribbles pseudokinase 2 | 0.00383037 |
| B3GNT1 | 0.00382011 | |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00381261 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00381081 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00380767 |
| VWF | von Willebrand factor | 0.00379972 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00379688 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00379316 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00378583 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00378119 |
| EPPK1 | epiplakin 1 | 0.0037807 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00378057 |
| FZD6 | frizzled class receptor 6 | 0.00376725 |
| MSN | moesin | 0.00376122 |
| TUBD1 | tubulin, delta 1 | 0.00375969 |
| NPC2 | Niemann-Pick disease, type C2 | 0.003758 |
| NREP | neuronal regeneration related protein | 0.00374386 |
| LRRC41 | leucine rich repeat containing 41 | 0.00372517 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00372317 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00372311 |
| GAB2 | GRB2-associated binding protein 2 | 0.00371638 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00369981 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00369243 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00366984 |
| CFB | complement factor B | 0.00366834 |
| ZNF91 | zinc finger protein 91 | 0.00366747 |
| CAVIN1 | caveolae associated protein 1 | 0.00366712 |
| EPHA1 | EPH receptor A1 | 0.00366637 |
| DAPK1 | death-associated protein kinase 1 | 0.00366558 |
| SMAD4 | SMAD family member 4 | 0.00366303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0167567 |
| NVL | nuclear VCP-like | -0.00842552 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00838568 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00826248 |
| MX1 | MX dynamin-like GTPase 1 | -0.00801456 |
| ATF3 | activating transcription factor 3 | -0.00790323 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00773123 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00770074 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00738288 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00729186 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0071437 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.0071112 |
| GNAS | GNAS complex locus | -0.0069788 |
| KRT5 | keratin 5, type II | -0.00694213 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00691943 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00683718 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0067645 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00671243 |
| WIF1 | WNT inhibitory factor 1 | -0.00666754 |
| HTRA1 | HtrA serine peptidase 1 | -0.00666519 |
| PTN | pleiotrophin | -0.00657031 |
| LYPLA1 | lysophospholipase I | -0.00636447 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00619695 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00609725 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00601416 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00599459 |
| IRF7 | interferon regulatory factor 7 | -0.00597463 |
| KRT19 | keratin 19, type I | -0.00597445 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00594454 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | -0.00592251 |
| PERP | PERP, TP53 apoptosis effector | -0.0058496 |
| VNN1 | vanin 1 | -0.00582444 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00576289 |
| BEX4 | brain expressed, X-linked 4 | -0.00573779 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00571728 |
| MAOA | monoamine oxidase A | -0.00566507 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00562784 |
| DSP | desmoplakin | -0.00559716 |
| PGAP3 | post-GPI attachment to proteins 3 | -0.0055919 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00557418 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00553541 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00542829 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00537989 |
| GOLGA8A | golgin A8 family, member A | -0.00529662 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00527528 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00524938 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00524481 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00523199 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00520213 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -0.00520204 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00516721 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.005166 |
| ABHD6 | abhydrolase domain containing 6 | -0.00515279 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00512127 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.00509938 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00503321 |
| CLDN8 | claudin 8 | -0.00501715 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00498508 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00497785 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00497438 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | -0.00494296 |
| NKX3-1 | NK3 homeobox 1 | -0.00493762 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00487872 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.00484486 |
| FAM111A | family with sequence similarity 111, member A | -0.00483364 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.0048276 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00478761 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00477003 |
| FST | follistatin | -0.00475293 |
| IL17RB | interleukin 17 receptor B | -0.00474846 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00473851 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00472848 |
| NAV2 | neuron navigator 2 | -0.00470912 |
| GLOD4 | glyoxalase domain containing 4 | -0.00470081 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00468814 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00467891 |
| NOSIP | nitric oxide synthase interacting protein | -0.00466862 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.00466443 |
| IL1R1 | interleukin 1 receptor, type I | -0.00464283 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00463582 |
| PXDC1 | PX domain containing 1 | -0.00460676 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00459564 |
| APOD | apolipoprotein D | -0.00458744 |
| EGR3 | early growth response 3 | -0.00458643 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00458043 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0045597 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00455886 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00455734 |
| RGS10 | regulator of G-protein signaling 10 | -0.00455669 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.00452062 |
| ACAN | aggrecan | -0.00450333 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0044984 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00447708 |
| PENK | proenkephalin | -0.00446792 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.00446622 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00446207 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00445964 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00443667 |
| SDC4 | syndecan 4 | -0.00440969 |
| CRYM | crystallin, mu | -0.0044091 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00440578 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.00438856 |
| KIAA0226L | KIAA0226-like | -0.00438817 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00438403 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00435852 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.0043507 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | -0.00432319 |
| IER5 | immediate early response 5 | -0.00431328 |
| E2F3 | E2F transcription factor 3 | -0.00429459 |
| PRAME | preferentially expressed antigen in melanoma | -0.00428839 |
| STAP2 | signal transducing adaptor family member 2 | -0.00425098 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00424851 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00424625 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0042402 |
| WDR26 | WD repeat domain 26 | -0.00423678 |
| DLX5 | distal-less homeobox 5 | -0.00423216 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00423097 |
| TRIM8 | tripartite motif containing 8 | -0.00420722 |
| CENPE | centromere protein E, 312kDa | -0.00420136 |
| KRT15 | keratin 15, type I | -0.00418891 |
| LBH | limb bud and heart development | -0.00417383 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00416214 |
| FCGBP | Fc fragment of IgG binding protein | -0.00415938 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00415445 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00414679 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00413354 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00413152 |
| KCTD5 | potassium channel tetramerization domain containing 5 | -0.00413005 |
| GTPBP2 | GTP binding protein 2 | -0.00411496 |
| CKAP2 | cytoskeleton associated protein 2 | -0.00410914 |
| SSPN | sarcospan | -0.00410811 |
| DKK4 | dickkopf WNT signaling pathway inhibitor 4 | -0.00410654 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -0.00410345 |
| UBQLN2 | ubiquilin 2 | -0.00410216 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00406966 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0040683 |
| PITX3 | paired-like homeodomain 3 | -0.00406706 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | -0.00406397 |
| NOTCH1 | notch 1 | -0.00406156 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00405252 |
| DLG5 | discs, large homolog 5 (Drosophila) | -0.00405248 |
| GSDMB | gasdermin B | -0.0040435 |
| KRT7 | keratin 7, type II | -0.00403774 |
| ZGPAT | zinc finger, CCCH-type with G patch domain | -0.004037 |
| PLXNA1 | plexin A1 | -0.00402668 |
| BAX | BCL2-associated X protein | -0.00401639 |
| RAB6A | RAB6A, member RAS oncogene family | -0.00401465 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00399915 |
| SELENBP1 | selenium binding protein 1 | -0.00399443 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00399337 |
| GDF15 | growth differentiation factor 15 | -0.00398922 |
| ZNF586 | zinc finger protein 586 | -0.00397659 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00396534 |
| MAGEA11 | melanoma antigen family A11 | -0.00396275 |
| RCAN1 | regulator of calcineurin 1 | -0.0039589 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.00393183 |
| FAM50B | family with sequence similarity 50, member B | -0.00392982 |
| IDS | iduronate 2-sulfatase | -0.00392544 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00392077 |
| MMP12 | matrix metallopeptidase 12 | -0.00391744 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00391544 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00390974 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00390477 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00390419 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.00389399 |
| TDG | thymine-DNA glycosylase | -0.00388782 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00388533 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00387982 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00387331 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.00387074 |
| COMT | catechol-O-methyltransferase | -0.0038641 |
| CCNF | cyclin F | -0.00385291 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.003846 |
| ERVMER34-1 | endogenous retrovirus group MER34, member 1 | -0.00383996 |
| PRR13 | proline rich 13 | -0.00383827 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00383768 |
| A2M | alpha-2-macroglobulin | -0.00382105 |
| CLEC1B | C-type lectin domain family 1, member B | -0.00381974 |
| IER2 | immediate early response 2 | -0.00379679 |
| HOXC10 | homeobox C10 | -0.00379354 |
| TSPAN1 | tetraspanin 1 | -0.00378327 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00377849 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00376426 |
| SSR4 | signal sequence receptor, delta | -0.00373937 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00373365 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00373244 |
| IFT20 | intraflagellar transport 20 | -0.00371282 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00368652 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 | -0.00368648 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00368555 |
| INHBA | inhibin, beta A | -0.00368531 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00366809 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00366431 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.00366327 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00365933 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | -0.00365021 |
| SUSD5 | sushi domain containing 5 | -0.00363612 |
| STK26 | serine/threonine protein kinase 26 | -0.00363273 |
| GRAMD1C | GRAM domain containing 1C | -0.00362786 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00362255 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.00358608 |
| MXRA8 | matrix-remodelling associated 8 | -0.00358391 |
| CAMP | cathelicidin antimicrobial peptide | -0.00357086 |
| CLDN7 | claudin 7 | -0.00357079 |
| CCND3 | cyclin D3 | -0.00356506 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00355784 |
| PRR5 | proline rich 5 (renal) | -0.00355163 |
| ZNF217 | zinc finger protein 217 | -0.00354858 |
| USP18 | ubiquitin specific peptidase 18 | -0.00354609 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | -0.00353792 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -0.00353251 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00353224 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00352885 |
| RANBP9 | RAN binding protein 9 | -0.00352804 |
| B4GALT3 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 | -0.00352313 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00351957 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | -0.00350842 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00350547 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00350047 |
| IER3 | immediate early response 3 | -0.00349963 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00349811 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00349525 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.00349509 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00349159 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00349142 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.00348839 |
| PRPF4B | pre-mRNA processing factor 4B | -0.00347772 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00347561 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 | -0.00347308 |
| RAP2C | RAP2C, member of RAS oncogene family | -0.00345596 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00344377 |
| IL27RA | interleukin 27 receptor, alpha | -0.00344233 |
| GPR137B | G protein-coupled receptor 137B | -0.00344074 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00343737 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00343581 |
| PDCD10 | programmed cell death 10 | -0.00343386 |
| HSPB3 | heat shock 27kDa protein 3 | -0.00343259 |
| CHI3L2 | chitinase 3-like 2 | -0.00342888 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00342323 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00341949 |
| GRP | gastrin-releasing peptide | -0.00341629 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00341148 |
| RTN2 | reticulon 2 | -0.00339901 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00339839 |
| HGD | homogentisate 1,2-dioxygenase | -0.00339572 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.00339197 |
| CCDC91 | coiled-coil domain containing 91 | -0.00338911 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00338529 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00338282 |
| PTCH1 | patched 1 | -0.00338005 |
