| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | suppressor of cytokine signaling 3|This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9021) |
| External Link | https://ncbi.nlm.nih.gov/gene/9021 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the SOCS3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0152136 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0150648 |
| CLU | clusterin | 0.0141853 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.0130327 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0123189 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0110703 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0109771 |
| NNMT | nicotinamide N-methyltransferase | 0.0105351 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0103431 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0100535 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0100214 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00995334 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00978283 |
| JMJD6 | jumonji domain containing 6 | 0.00929908 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00928886 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00927543 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00922286 |
| MXRA7 | matrix-remodelling associated 7 | 0.00920136 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00915805 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00911179 |
| C1R | complement component 1, r subcomponent | 0.00898776 |
| RGS1 | regulator of G-protein signaling 1 | 0.00893022 |
| CTSK | cathepsin K | 0.00878457 |
| ZNF160 | zinc finger protein 160 | 0.00854765 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00853071 |
| C1S | complement component 1, s subcomponent | 0.00846802 |
| LUM | lumican | 0.00835059 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00834788 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00824621 |
| EPHB2 | EPH receptor B2 | 0.00824514 |
| TOB1 | transducer of ERBB2, 1 | 0.00819668 |
| DCN | decorin | 0.00805769 |
| TNS3 | tensin 3 | 0.00804029 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00802857 |
| DSE | dermatan sulfate epimerase | 0.00799129 |
| IL7R | interleukin 7 receptor | 0.00791756 |
| GAS1 | growth arrest-specific 1 | 0.00787057 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00783236 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00782571 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00782306 |
| GPX1 | glutathione peroxidase 1 | 0.00779247 |
| SNAI2 | snail family zinc finger 2 | 0.00769783 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00767315 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.0076668 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00756976 |
| SIK1 | salt-inducible kinase 1 | 0.00755332 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00754041 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00752084 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00749861 |
| EFNB2 | ephrin-B2 | 0.00748027 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00744421 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00743468 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00739376 |
| REEP1 | receptor accessory protein 1 | 0.00730214 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00724112 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00723736 |
| LRRC15 | leucine rich repeat containing 15 | 0.00718831 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00715767 |
| ASPN | asporin | 0.00708915 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 0.00708755 |
| PLXNC1 | plexin C1 | 0.0070584 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00704443 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00697781 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00696448 |
| LOXL2 | lysyl oxidase-like 2 | 0.00692 |
| FOXF1 | forkhead box F1 | 0.00691754 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.00691589 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00690335 |
| FRZB | frizzled-related protein | 0.00684906 |
| MMP9 | matrix metallopeptidase 9 | 0.00679013 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00676314 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00674947 |
| KLHL21 | kelch-like family member 21 | 0.00673273 |
| ZNF264 | zinc finger protein 264 | 0.00670581 |
| BBX | bobby sox homolog (Drosophila) | 0.00666419 |
| TECR | trans-2,3-enoyl-CoA reductase | 0.00664281 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00664171 |
| SARAF | store-operated calcium entry-associated regulatory factor | 0.00660915 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00659784 |
| CST7 | cystatin F (leukocystatin) | 0.00656958 |
| SLC16A6 | solute carrier family 16, member 6 | 0.00652285 |
| TPD52 | tumor protein D52 | 0.00652036 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.0065083 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00648052 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00646597 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00640592 |
| NOTCH2NL | notch 2 N-terminal like | 0.00639887 |
| S100P | S100 calcium binding protein P | 0.00638934 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00637948 |
| ATP9A | ATPase, class II, type 9A | 0.00637089 |
| IL6R | interleukin 6 receptor | 0.006364 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00635454 |
| CFB | complement factor B | 0.00634569 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.00631847 |
| ACKR3 | atypical chemokine receptor 3 | 0.00631036 |
| FSTL1 | follistatin-like 1 | 0.00628018 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.0062626 |
| COL3A1 | collagen, type III, alpha 1 | 0.00626147 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00625783 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00624946 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.00624792 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00624559 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00623926 |
| LAGE3 | L antigen family, member 3 | 0.00623321 |
| TSPAN13 | tetraspanin 13 | 0.0061705 |
| ZNF587 | zinc finger protein 587 | 0.0061673 |
| TOX3 | TOX high mobility group box family member 3 | 0.00615393 |
| COMP | cartilage oligomeric matrix protein | 0.00612633 |
| PRDX2 | peroxiredoxin 2 | 0.00612199 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 | 0.00612052 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00611684 |
| RAPSN | receptor-associated protein of the synapse | 0.00611254 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00609885 |
| PLS3 | plastin 3 | 0.00607045 |
| LYPLA1 | lysophospholipase I | 0.0060474 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00600284 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00597516 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | 0.00597348 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 0.00596702 |
| NID2 | nidogen 2 (osteonidogen) | 0.00595589 |
| HMGB3 | high mobility group box 3 | 0.00593584 |
| IL2RB | interleukin 2 receptor, beta | 0.0059355 |
| FBXO2 | F-box protein 2 | 0.00593466 |
| ZNF721 | zinc finger protein 721 | 0.00591584 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00589264 |
| FASN | fatty acid synthase | 0.0058896 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00588915 |
| STK10 | serine/threonine kinase 10 | 0.00588513 |
| TFR2 | transferrin receptor 2 | 0.0058713 |
| RNF167 | ring finger protein 167 | 0.00585342 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00584653 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00584631 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.00584272 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.00583687 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | 0.00582543 |
| PRR11 | proline rich 11 | 0.00582113 |
| KIAA0355 | KIAA0355 | 0.00581799 |
| JAM3 | junctional adhesion molecule 3 | 0.00579601 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00579294 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00577558 |
| FAM13B | family with sequence similarity 13, member B | 0.00577105 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.0057674 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00576261 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00576065 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00574993 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00574611 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00573941 |
| ATMIN | ATM interactor | 0.00573915 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00573899 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00571695 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0057008 |
| MCOLN1 | mucolipin 1 | 0.00569829 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.00569514 |
| PRKCZ | protein kinase C, zeta | 0.00568448 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.00567209 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00564415 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.00564366 |
| LYRM1 | LYR motif containing 1 | 0.00563051 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.005622 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00559202 |
| CBR4 | carbonyl reductase 4 | 0.00557967 |
| ADIRF | adipogenesis regulatory factor | 0.00556751 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00556289 |
| CLGN | calmegin | 0.00555604 |
| TMEM14A | transmembrane protein 14A | 0.00555461 |
| COL8A2 | collagen, type VIII, alpha 2 | 0.00555314 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00555293 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | 0.00553878 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00550982 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00550787 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00550208 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0055005 |
| ITGAV | integrin, alpha V | 0.00550032 |
| HELLS | helicase, lymphoid-specific | 0.00549376 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00548266 |
| AUTS2 | autism susceptibility candidate 2 | 0.00547557 |
| RUNX3 | runt-related transcription factor 3 | 0.00547061 |
| FAM8A1 | family with sequence similarity 8, member A1 | 0.0054702 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.00545223 |
| MED13L | mediator complex subunit 13-like | 0.00544956 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.00543757 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 | 0.00543568 |
| DGKZ | diacylglycerol kinase, zeta | 0.00543426 |
| STAG2 | stromal antigen 2 | 0.00541119 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00540525 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00539783 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00537279 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | 0.00536625 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | 0.0053483 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00533916 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00533711 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00531829 |
| ERLIN2 | ER lipid raft associated 2 | 0.00531797 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00531685 |
| FERMT2 | fermitin family member 2 | 0.00531367 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | 0.00531108 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00531103 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00530098 |
| ACAA2 | acetyl-CoA acyltransferase 2 | 0.00529716 |
| PON2 | paraoxonase 2 | 0.00529541 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00528061 |
| ADRA2A | adrenoceptor alpha 2A | 0.0052796 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00527048 |
| CERK | ceramide kinase | 0.0052659 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00526463 |
| ANGPTL2 | angiopoietin-like 2 | 0.00524948 |
| SDC1 | syndecan 1 | 0.00524787 |
| EVA1B | eva-1 homolog B (C. elegans) | 0.00524661 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00524267 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 0.00523354 |
| DVL1 | dishevelled segment polarity protein 1 | 0.00520903 |
| TAGLN | transgelin | 0.00520698 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00519102 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00519072 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | 0.00519071 |
| PTGES | prostaglandin E synthase | 0.0051882 |
| PHF20 | PHD finger protein 20 | 0.00517469 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00516731 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.00515971 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.00515028 |
| ADCY9 | adenylate cyclase 9 | 0.00514132 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00512981 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.00512496 |
| ZNF652 | zinc finger protein 652 | 0.00512174 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00512107 |
| THY1 | Thy-1 cell surface antigen | 0.00511678 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00511549 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00510744 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00509615 |
| TMEM184B | transmembrane protein 184B | 0.00509192 |
| FYB1 | FYN binding protein 1 | 0.00508375 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00507462 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00507155 |
| SFXN3 | sideroflexin 3 | 0.00505965 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.00505731 |
| KAZN | kazrin, periplakin interacting protein | 0.00505285 |
| KIAA0232 | KIAA0232 | 0.0050392 |
| DDHD2 | DDHD domain containing 2 | 0.00503705 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00503584 |
| RETREG2 | reticulophagy regulator family member 2 | 0.00497751 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | 0.00497388 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00497362 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00496089 |
| STAB1 | stabilin 1 | 0.00495696 |
| SMC5 | structural maintenance of chromosomes 5 | 0.00495112 |
| EPYC | epiphycan | 0.00495107 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00495069 |
| XYLT1 | xylosyltransferase I | 0.00494353 |
| BANP | BTG3 associated nuclear protein | 0.00493757 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00492691 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0130629 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0114844 |
| PRAME | preferentially expressed antigen in melanoma | -0.00985279 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00976028 |
| CSTA | cystatin A (stefin A) | -0.00965116 |
| TGM2 | transglutaminase 2 | -0.00960538 |
| ANXA3 | annexin A3 | -0.00952785 |
| TSPAN1 | tetraspanin 1 | -0.00927936 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00909457 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0087143 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00865446 |
| MAOA | monoamine oxidase A | -0.0085212 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00850157 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00840624 |
| ANXA1 | annexin A1 | -0.0083259 |
| TGFA | transforming growth factor, alpha | -0.0083072 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0082981 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00814817 |
| CD200 | CD200 molecule | -0.00805135 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00804573 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00804393 |
| MGP | matrix Gla protein | -0.00800874 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00798656 |
| ANO10 | anoctamin 10 | -0.00796184 |
| KRT19 | keratin 19, type I | -0.00795676 |
| EMX2 | empty spiracles homeobox 2 | -0.00791073 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.00785102 |
| ARG2 | arginase 2 | -0.0078219 |
| H1-2 | H1.2 linker histone, cluster member | -0.00780752 |
| FHL1 | four and a half LIM domains 1 | -0.00778803 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00765029 |
| CTSH | cathepsin H | -0.00763854 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00761238 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0075607 |
| LTF | lactotransferrin | -0.00750879 |
| S100A9 | S100 calcium binding protein A9 | -0.00744515 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00742846 |
| EPCAM | epithelial cell adhesion molecule | -0.00724696 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00723964 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00723285 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00714388 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.00713387 |
| TPD52L1 | tumor protein D52-like 1 | -0.00710633 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00704425 |
| MALL | mal, T-cell differentiation protein-like | -0.00704159 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00700151 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.0069642 |
| MECOM | MDS1 and EVI1 complex locus | -0.00694417 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00683887 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00678989 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00675479 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00674597 |
| ITGA6 | integrin, alpha 6 | -0.00674231 |
| RAB25 | RAB25, member RAS oncogene family | -0.00673985 |
| SCEL | sciellin | -0.00671223 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00663444 |
| MMP7 | matrix metallopeptidase 7 | -0.0066078 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.006591 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00657356 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00654496 |
| IFT57 | intraflagellar transport 57 | -0.00653839 |
| ATG5 | autophagy related 5 | -0.00653586 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00650467 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00644142 |
| KRT15 | keratin 15, type I | -0.00642601 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | -0.00641608 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00641321 |
| GUCY2C | guanylate cyclase 2C | -0.00640629 |
| NMD3 | NMD3 ribosome export adaptor | -0.00639861 |
| SELENOT | selenoprotein T | -0.00636644 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00634144 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00633083 |
| MEIS2 | Meis homeobox 2 | -0.00630625 |
| EDN3 | endothelin 3 | -0.00627484 |
| EMP1 | epithelial membrane protein 1 | -0.00621857 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00613487 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00612811 |
| ANXA2 | annexin A2 | -0.00611902 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00610841 |
| RAB38 | RAB38, member RAS oncogene family | -0.00609933 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00609822 |
| SPRR3 | small proline-rich protein 3 | -0.00609275 |
| MPZL2 | myelin protein zero-like 2 | -0.00608834 |
| TAOK3 | TAO kinase 3 | -0.00603897 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00602754 |
| AGPS | alkylglycerone phosphate synthase | -0.00602522 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0060073 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00600327 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0059797 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0059776 |
| INAVA | innate immunity activator | -0.00597274 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -0.00596147 |
| TSPAN8 | tetraspanin 8 | -0.00593515 |
| LAMC2 | laminin, gamma 2 | -0.00592465 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00590845 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00589826 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.00587138 |
| CCND2 | cyclin D2 | -0.00584656 |
| CCDC88A | coiled-coil domain containing 88A | -0.00584055 |
| SMAGP | small cell adhesion glycoprotein | -0.00583964 |
| TNNC1 | troponin C type 1 (slow) | -0.00583547 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00583475 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00581499 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00581493 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00581481 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00581266 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.00580883 |
| TTN | titin | -0.0057952 |
| MYBPC1 | myosin binding protein C, slow type | -0.00578929 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00578613 |
| C12ORF4 | chromosome 12 open reading frame 4 | -0.00574828 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00574791 |
| CTSE | cathepsin E | -0.00573393 |
| CALCRL | calcitonin receptor-like | -0.00572872 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.00571134 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00570858 |
| DES | desmin | -0.00570435 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00569182 |
| MAPK14 | mitogen-activated protein kinase 14 | -0.00569009 |
| XPO4 | exportin 4 | -0.00568454 |
| MSMB | microseminoprotein, beta- | -0.00568018 |
| SPRR1B | small proline-rich protein 1B | -0.00566585 |
| RGS10 | regulator of G-protein signaling 10 | -0.00563313 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00563306 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.0056294 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00561178 |
| EDN1 | endothelin 1 | -0.00561108 |
| FERMT1 | fermitin family member 1 | -0.00560314 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.00558538 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00553551 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00548931 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00543979 |
| SMYD2 | SET and MYND domain containing 2 | -0.00543109 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.00542737 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00540856 |
| CES1 | carboxylesterase 1 | -0.00539144 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00538678 |
| CD1D | CD1d molecule | -0.00537076 |
| VCAN | versican | -0.00536234 |
| UBASH3A | ubiquitin associated and SH3 domain containing A | -0.00534259 |
| CRYAB | crystallin, alpha B | -0.00533304 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00532933 |
| CTSZ | cathepsin Z | -0.00532606 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.00531047 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00530634 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00528126 |
| ZNF195 | zinc finger protein 195 | -0.00527944 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00527025 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0052666 |
| CDC42 | cell division cycle 42 | -0.0052657 |
| GPC3 | glypican 3 | -0.00521559 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00521495 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00520353 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00519889 |
| PHOX2B | paired-like homeobox 2b | -0.00519376 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00518638 |
| B9D1 | B9 protein domain 1 | -0.00517694 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.00514971 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00514758 |
| CLDN1 | claudin 1 | -0.00514313 |
| HAND2-AS1 | HAND2 antisense RNA 1 (head to head) | -0.00512833 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00512796 |
| RPL14 | ribosomal protein L14 | -0.00511518 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00510709 |
| KRT7 | keratin 7, type II | -0.00509827 |
| EXOC5 | exocyst complex component 5 | -0.00509169 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | -0.00508819 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00508666 |
| HOXB6 | homeobox B6 | -0.00507707 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00507667 |
| TNF | tumor necrosis factor | -0.00505098 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.00504061 |
| MAGEA4 | melanoma antigen family A4 | -0.00503149 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -0.00502919 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | -0.00502672 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00499269 |
| LDLR | low density lipoprotein receptor | -0.00499099 |
| KLK5 | kallikrein-related peptidase 5 | -0.00498913 |
| CDH16 | cadherin 16, KSP-cadherin | -0.00495543 |
| PLS1 | plastin 1 | -0.00495511 |
| TMEM135 | transmembrane protein 135 | -0.00495454 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00495447 |
| CLDN10 | claudin 10 | -0.00493325 |
| RTCA | RNA 3'-terminal phosphate cyclase | -0.00493164 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00493005 |
| FZD6 | frizzled class receptor 6 | -0.00492352 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.00490982 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00490928 |
| AOC1 | amine oxidase, copper containing 1 | -0.0048963 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00487872 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00486653 |
| COG5 | component of oligomeric golgi complex 5 | -0.00486504 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00486461 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00485074 |
| TSPAN6 | tetraspanin 6 | -0.00485017 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.00484813 |
| IFI44 | interferon-induced protein 44 | -0.00484594 |
| HOXB7 | homeobox B7 | -0.00483734 |
| PGC | progastricsin (pepsinogen C) | -0.00482733 |
| DLAT | dihydrolipoamide S-acetyltransferase | -0.00481922 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00481373 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00480706 |
| MYO1B | myosin IB | -0.00479872 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00479534 |
| TDRD12 | tudor domain containing 12 | -0.00479201 |
| AFP | alpha-fetoprotein | -0.00478997 |
| TMC5 | transmembrane channel-like 5 | -0.00478393 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.0047794 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00477776 |
| BEX1 | brain expressed, X-linked 1 | -0.00476564 |
| AGR2 | anterior gradient 2 | -0.00476481 |
| ETV5 | ets variant 5 | -0.00475902 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.00475826 |
| LMOD1 | leiomodin 1 (smooth muscle) | -0.00473477 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00473179 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00473091 |
| TESC | tescalcin | -0.00472791 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0047232 |
| ASRGL1 | asparaginase like 1 | -0.00471581 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.00470873 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00469815 |
| YBX3 | Y box binding protein 3 | -0.00468603 |
| ACP1 | acid phosphatase 1, soluble | -0.00468206 |
| OLA1 | Obg-like ATPase 1 | -0.00467783 |
| LRRC42 | leucine rich repeat containing 42 | -0.00467509 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00467031 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00466636 |
| KLF6 | Kruppel-like factor 6 | -0.00466296 |
| TPTE | transmembrane phosphatase with tensin homology | -0.00465112 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00464176 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00463618 |
| IPO13 | importin 13 | -0.00463005 |
| CTTN | cortactin | -0.00462792 |
| ZNF165 | zinc finger protein 165 | -0.00462671 |
| AFF4 | AF4/FMR2 family, member 4 | -0.00462295 |
| PLEK2 | pleckstrin 2 | -0.00461867 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00461764 |
| POSTN | periostin, osteoblast specific factor | -0.00461708 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 | -0.00461363 |
| S100A14 | S100 calcium binding protein A14 | -0.00461089 |
| ANXA11 | annexin A11 | -0.0046032 |
| CALB1 | calbindin 1, 28kDa | -0.00460156 |
| HEBP2 | heme binding protein 2 | -0.00459055 |
| REG1A | regenerating islet-derived 1 alpha | -0.00459015 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.00458353 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | -0.00457976 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | -0.00457801 |
| FOSL2 | FOS-like antigen 2 | -0.00457528 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.00457344 |
| PARL | presenilin associated, rhomboid-like | -0.00457132 |
