| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | suppressor of cytokine signaling 6|The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9306) |
| External Link | https://ncbi.nlm.nih.gov/gene/9306 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the SOCS6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0145497 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0135524 |
| IRS2 | insulin receptor substrate 2 | 0.012345 |
| LTF | lactotransferrin | 0.0119324 |
| S100P | S100 calcium binding protein P | 0.0113724 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.0113674 |
| SYNGR3 | synaptogyrin 3 | 0.0111534 |
| XIC | X chromosome inactivation center | 0.0108925 |
| ODC1 | ornithine decarboxylase 1 | 0.0106339 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0106307 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0105595 |
| RNF167 | ring finger protein 167 | 0.0103819 |
| LAMC2 | laminin, gamma 2 | 0.0101775 |
| COCH | cochlin | 0.0100971 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00985246 |
| PSAP | prosaposin | 0.00965375 |
| PRAME | preferentially expressed antigen in melanoma | 0.00962957 |
| KLF11 | Kruppel-like factor 11 | 0.00961895 |
| AGR2 | anterior gradient 2 | 0.00960582 |
| ATF3 | activating transcription factor 3 | 0.00950564 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00909471 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00906299 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00891873 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00881106 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00877716 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00869624 |
| GALC | galactosylceramidase | 0.00858777 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0085134 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00846553 |
| MAGEA3 | melanoma antigen family A3 | 0.00844319 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00844256 |
| SNX11 | sorting nexin 11 | 0.00842938 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00842477 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.0083134 |
| KYNU | kynureninase | 0.00824714 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00816586 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 0.00813504 |
| JAG1 | jagged 1 | 0.00809503 |
| IL32 | interleukin 32 | 0.00806998 |
| TFF1 | trefoil factor 1 | 0.00806916 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00801129 |
| MSMB | microseminoprotein, beta- | 0.00801107 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00796039 |
| CHGB | chromogranin B | 0.00795735 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00793413 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00793072 |
| FOSL2 | FOS-like antigen 2 | 0.00789584 |
| CDC20 | cell division cycle 20 | 0.00789232 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00779642 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00776759 |
| TUFT1 | tuftelin 1 | 0.0077567 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00772114 |
| CAPN3 | calpain 3, (p94) | 0.00771318 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00770115 |
| GRN | granulin | 0.00764041 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | 0.00760933 |
| CST3 | cystatin C | 0.00759618 |
| TARP | TCR gamma alternate reading frame protein | 0.00758965 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00749556 |
| PLK2 | polo-like kinase 2 | 0.0074908 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00740249 |
| JUNB | jun B proto-oncogene | 0.00738436 |
| ANO10 | anoctamin 10 | 0.00730492 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00730176 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0072723 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00723201 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00723111 |
| LY75 | lymphocyte antigen 75 | 0.00721519 |
| ITK | IL2-inducible T-cell kinase | 0.00718965 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00717035 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00711247 |
| NEFH | neurofilament, heavy polypeptide | 0.00708482 |
| TKTL1 | transketolase-like 1 | 0.00701594 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00700552 |
| TGM2 | transglutaminase 2 | 0.00699371 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00696275 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00695886 |
| OFD1 | oral-facial-digital syndrome 1 | 0.00695608 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00695206 |
| ATG101 | autophagy related 101 | 0.00691095 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00690033 |
| TLK2 | tousled-like kinase 2 | 0.00689988 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00688551 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00688448 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00687766 |
| SIK1 | salt-inducible kinase 1 | 0.00687601 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00687073 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00686474 |
| CHEK2 | checkpoint kinase 2 | 0.00685368 |
| IL2RG | interleukin 2 receptor, gamma | 0.00684413 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00682624 |
| DST | dystonin | 0.00681824 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.00681301 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00680539 |
| ACTN1 | actinin, alpha 1 | 0.00673129 |
| CCND3 | cyclin D3 | 0.00667453 |
| IER5 | immediate early response 5 | 0.00667349 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.00665722 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.00664597 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00661785 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00661572 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00659996 |
| HMOX1 | heme oxygenase 1 | 0.00659656 |
| CRYAB | crystallin, alpha B | 0.0065956 |
| VEGFA | vascular endothelial growth factor A | 0.00653284 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0065125 |
| GCH1 | GTP cyclohydrolase 1 | 0.00649048 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.0064706 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00646491 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00645072 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | 0.00644778 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00643266 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00642119 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00641365 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.00641247 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00640668 |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.00639376 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.00636612 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0063618 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00631301 |
| ITGB4 | integrin, beta 4 | 0.00630934 |
| VGLL4 | vestigial-like family member 4 | 0.00625849 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00625713 |
| LYST | lysosomal trafficking regulator | 0.00624524 |
| PFKP | phosphofructokinase, platelet | 0.00624201 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00621652 |
| LCN2 | lipocalin 2 | 0.00619037 |
| IPO13 | importin 13 | 0.00617311 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00616946 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.0061637 |
| MAGED1 | melanoma antigen family D1 | 0.00614537 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00614174 |
| PTHLH | parathyroid hormone-like hormone | 0.00613469 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00613065 |
| LBH | limb bud and heart development | 0.00612871 |
| COL9A2 | collagen, type IX, alpha 2 | 0.0061257 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00610226 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00610071 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.00609873 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00609068 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00608337 |
| GPX2 | glutathione peroxidase 2 | 0.00607334 |
| MAGEA4 | melanoma antigen family A4 | 0.00605974 |
| NKX3-1 | NK3 homeobox 1 | 0.00605346 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00602808 |
| CALB1 | calbindin 1, 28kDa | 0.00601893 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00600957 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00599644 |
| MINK1 | misshapen-like kinase 1 | 0.00598982 |
| DUSP5 | dual specificity phosphatase 5 | 0.00598841 |
| KLK11 | kallikrein-related peptidase 11 | 0.00598273 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00596877 |
| RHOB | ras homolog family member B | 0.0059655 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00592058 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00591627 |
| RRAGD | Ras-related GTP binding D | 0.00588966 |
| FLNA | filamin A, alpha | 0.00586198 |
| CCDC88A | coiled-coil domain containing 88A | 0.00582343 |
| LAMA3 | laminin, alpha 3 | 0.00582155 |
| IL7R | interleukin 7 receptor | 0.00581421 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00580433 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00578733 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00577901 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00577192 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00574627 |
| TPTE | transmembrane phosphatase with tensin homology | 0.00574592 |
| ZNF331 | zinc finger protein 331 | 0.00574144 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00574039 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00573586 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00572737 |
| FA2H | fatty acid 2-hydroxylase | 0.00572222 |
| DRG1 | developmentally regulated GTP binding protein 1 | 0.00572067 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.00570979 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00570375 |
| MX1 | MX dynamin-like GTPase 1 | 0.00569363 |
| MMP7 | matrix metallopeptidase 7 | 0.00568045 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00567484 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00567394 |
| PYGB | phosphorylase, glycogen; brain | 0.00566597 |
| MMP9 | matrix metallopeptidase 9 | 0.00566568 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00565853 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00565728 |
| GPM6B | glycoprotein M6B | 0.00565428 |
| WIF1 | WNT inhibitory factor 1 | 0.00565415 |
| IL2RB | interleukin 2 receptor, beta | 0.00565363 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00564636 |
| IRF7 | interferon regulatory factor 7 | 0.00562458 |
| DES | desmin | 0.00560131 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00560122 |
| CD19 | CD19 molecule | 0.00559956 |
| CDCP1 | CUB domain containing protein 1 | 0.00558457 |
| GPI | glucose-6-phosphate isomerase | 0.00556405 |
| OPTN | optineurin | 0.00555308 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.00553329 |
| COG7 | component of oligomeric golgi complex 7 | 0.00552356 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00552211 |
| PKP1 | plakophilin 1 | 0.00552105 |
| HAL | histidine ammonia-lyase | 0.00551298 |
| TYMP | thymidine phosphorylase | 0.00549896 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00549387 |
| PLBD1 | phospholipase B domain containing 1 | 0.00549227 |
| MAGEA12 | melanoma antigen family A12 | 0.00548717 |
| CLASRP | CLK4-associating serine/arginine rich protein | 0.00548512 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.00548427 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00547874 |
| ITGAV | integrin, alpha V | 0.0054756 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00547208 |
| TAPBP | TAP binding protein (tapasin) | 0.00545197 |
| CST7 | cystatin F (leukocystatin) | 0.00545108 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.00544792 |
| ELOVL1 | ELOVL fatty acid elongase 1 | 0.00543965 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00542216 |
| IRF1 | interferon regulatory factor 1 | 0.00541153 |
| GATA6 | GATA binding protein 6 | 0.00539949 |
| CHMP4A | charged multivesicular body protein 4A | 0.00538737 |
| GM2A | GM2 ganglioside activator | 0.00537555 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.0053446 |
| POMZP3 | POM121 and ZP3 fusion | 0.00532639 |
| TEX10 | testis expressed 10 | 0.00531787 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00531353 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00531065 |
| SVIL | supervillin | 0.0053034 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00529759 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00527727 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00527233 |
| KLK1 | kallikrein 1 | 0.00526649 |
| MRTFA | myocardin related transcription factor A | 0.0052639 |
| SPAG1 | sperm associated antigen 1 | 0.00524725 |
| FGF13 | fibroblast growth factor 13 | 0.00523157 |
| HGD | homogentisate 1,2-dioxygenase | 0.00522673 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | 0.00521471 |
| GPX3 | glutathione peroxidase 3 | 0.00520764 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00520493 |
| TSPAN15 | tetraspanin 15 | 0.00519914 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00519643 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 0.00519321 |
| PSEN1 | presenilin 1 | 0.00517912 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | 0.00517669 |
| JUP | junction plakoglobin | 0.00516666 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00516502 |
| TATDN2 | TatD DNase domain containing 2 | 0.00515924 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00515364 |
| CCN3 | cellular communication network factor 3 | 0.00515233 |
| CTPS1 | CTP synthase 1 | 0.00514193 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00513758 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00513457 |
| ACO2 | aconitase 2, mitochondrial | 0.00512713 |
| FHL2 | four and a half LIM domains 2 | 0.00511959 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00511957 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SDC2 | syndecan 2 | -0.0158403 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.015028 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.0137113 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0129536 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0119035 |
| CFI | complement factor I | -0.0117138 |
| MECOM | MDS1 and EVI1 complex locus | -0.0112602 |
| EMP2 | epithelial membrane protein 2 | -0.0110815 |
| MDFIC | MyoD family inhibitor domain containing | -0.0110207 |
| TMSB15A | thymosin beta 15a | -0.0109387 |
| EMP1 | epithelial membrane protein 1 | -0.0105974 |
| ASPH | aspartate beta-hydroxylase | -0.0104729 |
| METTL7A | methyltransferase like 7A | -0.0103164 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0100783 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00987299 |
| COL3A1 | collagen, type III, alpha 1 | -0.0097095 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00967612 |
| MMP1 | matrix metallopeptidase 1 | -0.0094908 |
| PRDX3 | peroxiredoxin 3 | -0.00947068 |
| CNN3 | calponin 3, acidic | -0.00945845 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00938899 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00933889 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00932903 |
| GAS1 | growth arrest-specific 1 | -0.00932335 |
| COLEC12 | collectin sub-family member 12 | -0.0092864 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00913594 |
| ASPN | asporin | -0.0090243 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00897196 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00896133 |
| SEPTIN10 | septin 10 | -0.00889247 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00873579 |
| ESR1 | estrogen receptor 1 | -0.00872147 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00859118 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00838265 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0083238 |
| DOK5 | docking protein 5 | -0.00829644 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00828236 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -0.00828167 |
| TXN | thioredoxin | -0.00826046 |
| PCLAF | PCNA clamp associated factor | -0.00825796 |
| ARMT1 | acidic residue methyltransferase 1 | -0.00821172 |
| TMEM126B | transmembrane protein 126B | -0.00817215 |
| FOXF1 | forkhead box F1 | -0.00815966 |
| RGCC | regulator of cell cycle | -0.00810572 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00805714 |
| LOX | lysyl oxidase | -0.00803279 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00802759 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00801701 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00794478 |
| MRPS28 | mitochondrial ribosomal protein S28 | -0.0078804 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00784888 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00782493 |
| RPA3 | replication protein A3, 14kDa | -0.00781295 |
| PRDX2 | peroxiredoxin 2 | -0.00772656 |
| ADIRF | adipogenesis regulatory factor | -0.00766739 |
| HNMT | histamine N-methyltransferase | -0.00766311 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -0.00759201 |
| HIP1 | huntingtin interacting protein 1 | -0.00754764 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.0075471 |
| RBBP4 | retinoblastoma binding protein 4 | -0.0075192 |
| FSTL1 | follistatin-like 1 | -0.00745985 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00737076 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00732128 |
| CRYZ | crystallin, zeta (quinone reductase) | -0.00731474 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.00723521 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00721512 |
| DCK | deoxycytidine kinase | -0.00718854 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00717202 |
| COL1A2 | collagen, type I, alpha 2 | -0.00716142 |
| CP | ceruloplasmin (ferroxidase) | -0.00711152 |
| FOLR1 | folate receptor 1 (adult) | -0.00708911 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00708544 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00708199 |
| CRIP2 | cysteine-rich protein 2 | -0.00707329 |
| TFDP1 | transcription factor Dp-1 | -0.00703361 |
| ELN | elastin | -0.00702194 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00700865 |
| HMGB1 | high mobility group box 1 | -0.00697726 |
| RTN2 | reticulon 2 | -0.00697009 |
| NUTF2 | nuclear transport factor 2 | -0.00694783 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00690793 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00689175 |
| KRT15 | keratin 15, type I | -0.00688204 |
| RIDA | reactive intermediate imine deaminase A homolog | -0.00686994 |
| TNC | tenascin C | -0.00680581 |
| DPY19L4 | dpy-19-like 4 (C. elegans) | -0.0067955 |
| OLFM1 | olfactomedin 1 | -0.00673623 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00668793 |
| MRPL13 | mitochondrial ribosomal protein L13 | -0.00666974 |
| COMMD10 | COMM domain containing 10 | -0.00663535 |
| NES | nestin | -0.0066239 |
| NINJ2 | ninjurin 2 | -0.00662353 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.0066103 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.0065654 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00656433 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0065424 |
| BEX1 | brain expressed, X-linked 1 | -0.00650694 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00647389 |
| SCP2 | sterol carrier protein 2 | -0.00647005 |
| BGN | biglycan | -0.00646409 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | -0.00646366 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00643433 |
| MGP | matrix Gla protein | -0.0064216 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00641309 |
| SIRT3 | sirtuin 3 | -0.00639761 |
| LRRC17 | leucine rich repeat containing 17 | -0.00638254 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.00638182 |
| YIPF5 | Yip1 domain family, member 5 | -0.00637665 |
| CCNA2 | cyclin A2 | -0.00632617 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00630322 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00629896 |
| KRT19 | keratin 19, type I | -0.00627954 |
| ASF1A | anti-silencing function 1A histone chaperone | -0.00627623 |
| FZD6 | frizzled class receptor 6 | -0.00626575 |
| TMEM14A | transmembrane protein 14A | -0.00625618 |
| TSPAN6 | tetraspanin 6 | -0.00623519 |
| RGS5 | regulator of G-protein signaling 5 | -0.00622055 |
| OPHN1 | oligophrenin 1 | -0.00618419 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.0061685 |
| MSX1 | msh homeobox 1 | -0.00615778 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | -0.00615019 |
| PLIN1 | perilipin 1 | -0.00613179 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.00611485 |
| PXDN | peroxidasin | -0.00608038 |
| FRZB | frizzled-related protein | -0.00606573 |
| CD99 | CD99 molecule | -0.00606293 |
| COMP | cartilage oligomeric matrix protein | -0.00605258 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00605014 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00603929 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00603192 |
| LYPLA1 | lysophospholipase I | -0.00601757 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00601455 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00600701 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.00600651 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.00600418 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00599294 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00599285 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.0059925 |
| LY96 | lymphocyte antigen 96 | -0.00598477 |
| CFH | complement factor H | -0.00598428 |
| PBK | PDZ binding kinase | -0.00596883 |
| IL1R1 | interleukin 1 receptor, type I | -0.00595174 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00594656 |
| EMC2 | ER membrane protein complex subunit 2 | -0.00593875 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00593096 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00591907 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00591729 |
| DOCK1 | dedicator of cytokinesis 1 | -0.00591278 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00589945 |
| PRMT2 | protein arginine methyltransferase 2 | -0.00589842 |
| MGLL | monoglyceride lipase | -0.005874 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00582155 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00582127 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.00580845 |
| MED28 | mediator complex subunit 28 | -0.00579602 |
| ALB | albumin | -0.00579472 |
| HOXC6 | homeobox C6 | -0.00578861 |
| APIP | APAF1 interacting protein | -0.00577504 |
| TMEM204 | transmembrane protein 204 | -0.00577375 |
| ELOC | elongin C | -0.00576016 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00575315 |
| CETN3 | centrin, EF-hand protein, 3 | -0.00572088 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.0057183 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.00571503 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00569752 |
| C4BPA | complement component 4 binding protein, alpha | -0.00569708 |
| ANOS1 | anosmin 1 | -0.00568113 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00568051 |
| WDR76 | WD repeat domain 76 | -0.00566389 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | -0.00563585 |
| MAPT | microtubule-associated protein tau | -0.00562281 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00561226 |
| SELENOF | selenoprotein F | -0.00561205 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0056046 |
| TSPAN12 | tetraspanin 12 | -0.00559868 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00559494 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | -0.00559443 |
| SLC35A5 | solute carrier family 35, member A5 | -0.00558881 |
| NREP | neuronal regeneration related protein | -0.00558609 |
| LUM | lumican | -0.00558066 |
| TMEM45A | transmembrane protein 45A | -0.00556792 |
| CLDND1 | claudin domain containing 1 | -0.0055614 |
| MXRA8 | matrix-remodelling associated 8 | -0.00555884 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00555742 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00555682 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -0.0055413 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00551807 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.00550782 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00549283 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.0054635 |
| KRT13 | keratin 13, type I | -0.00546246 |
| FBXO3 | F-box protein 3 | -0.00545652 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.0054513 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00544825 |
| HOXA5 | homeobox A5 | -0.00542478 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00542108 |
| RECQL | RecQ helicase-like | -0.00540802 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00540259 |
| PPL | periplakin | -0.0053861 |
| IFT57 | intraflagellar transport 57 | -0.00537476 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.00536379 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00536233 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00535892 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00535581 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | -0.00534582 |
| DUT | deoxyuridine triphosphatase | -0.00534518 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00533864 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.0053352 |
| EXOC5 | exocyst complex component 5 | -0.00533359 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.0053203 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00531318 |
| DDHD2 | DDHD domain containing 2 | -0.00531149 |
| CALD1 | caldesmon 1 | -0.00530938 |
| CALR | calreticulin | -0.00530723 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00530687 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00529925 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00529685 |
| CCNE2 | cyclin E2 | -0.00528866 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | -0.00528758 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00527976 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00527453 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.00525897 |
| ANXA5 | annexin A5 | -0.00525607 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00525402 |
| PLSCR4 | phospholipid scramblase 4 | -0.00525302 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.0052255 |
| NMU | neuromedin U | -0.00522261 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00521768 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00521744 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00521275 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00520992 |
| GLUD2 | glutamate dehydrogenase 2 | -0.00520507 |
| HSBP1 | heat shock factor binding protein 1 | -0.0051897 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0051886 |
| SNAI2 | snail family zinc finger 2 | -0.00517911 |
| HDAC1 | histone deacetylase 1 | -0.00517659 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00517156 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | -0.0051616 |
| SSPN | sarcospan | -0.0051579 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.00515747 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.00515184 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00514961 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00514783 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | -0.00514355 |
| HEBP2 | heme binding protein 2 | -0.0051418 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00513928 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | -0.0051072 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0051064 |
