SOD1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description superoxide dismutase 1, soluble|The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6647)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SOD1
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Genes

277 co-expressed genes for SOD1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACLY ATP citrate lyase
ACOT13 acyl-CoA thioesterase 13
ACOT7 acyl-CoA thioesterase 7
AFG3L2 AFG3-like AAA ATPase 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALG8 ALG8, alpha-1,3-glucosyltransferase
ANAPC5 anaphase promoting complex subunit 5
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARF3 ADP-ribosylation factor 3
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATOX1 antioxidant 1 copper chaperone
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATXN10 ataxin 10
BANF1 barrier to autointegration factor 1
BCAP31 B-cell receptor-associated protein 31
BUB3 BUB3 mitotic checkpoint protein
BZW1 basic leucine zipper and W2 domains 1
C1QBP complement component 1, q subcomponent binding protein
C21ORF33 chromosome 21 open reading frame 33
C6ORF62 chromosome 6 open reading frame 62
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CANX calnexin
CBX3 chromobox homolog 3
CCNB1 cyclin B1
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC123 cell division cycle 123
CDC23 cell division cycle 23
CDK4 cyclin-dependent kinase 4
CFDP1 craniofacial development protein 1
CHERP calcium homeostasis endoplasmic reticulum protein
CLNS1A chloride channel, nucleotide-sensitive, 1A
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNIH1 cornichon family AMPA receptor auxiliary protein 1
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COPS5 COP9 signalosome subunit 5
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX5A cytochrome c oxidase subunit Va
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1
COX6C cytochrome c oxidase subunit VIc
COX7B cytochrome c oxidase subunit VIIb
CS citrate synthase
CSNK2B casein kinase 2, beta polypeptide
CTDNEP1 CTD nuclear envelope phosphatase 1
CYC1 cytochrome c-1
CYCS cytochrome c, somatic
DAP death-associated protein
DARS aspartyl-tRNA synthetase
DCTN2 dynactin 2 (p50)
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DEK DEK proto-oncogene
DGUOK deoxyguanosine kinase
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DLD dihydrolipoamide dehydrogenase
DOCK3 dedicator of cytokinesis 3
DRG1 developmentally regulated GTP binding protein 1
DYNLL1 dynein, light chain, LC8-type 1
EBAG9 estrogen receptor binding site associated, antigen, 9
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EI24 etoposide induced 2.4
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF4H eukaryotic translation initiation factor 4H
ENSA endosulfine alpha
ERH enhancer of rudimentary homolog (Drosophila)
ETFA electron-transfer-flavoprotein, alpha polypeptide
FAM120A family with sequence similarity 120A
FAM20B family with sequence similarity 20, member B
FBL fibrillarin
FBXW11 F-box and WD repeat domain containing 11
FDPS farnesyl diphosphate synthase
FEN1 flap structure-specific endonuclease 1
FIBP fibroblast growth factor (acidic) intracellular binding protein
FUS FUS RNA binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GANAB glucosidase, alpha; neutral AB
GGCT gamma-glutamylcyclotransferase
GLO1 glyoxalase I
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPN1 GPN-loop GTPase 1
GSPT1 G1 to S phase transition 1
H2AFZ H2A histone family, member Z
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAT1 histone acetyltransferase 1
HAX1 HCLS1 associated protein X-1
HCCS holocytochrome c synthase
HDAC2 histone deacetylase 2
HMGN1 high mobility group nucleosome binding domain 1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSBP1 heat shock factor binding protein 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFRD1 interferon-related developmental regulator 1
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
KARS lysyl-tRNA synthetase
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0101 KIAA0101
KIF2A kinesin heavy chain member 2A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LARP1 La ribonucleoprotein domain family, member 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYPLA1 lysophospholipase I
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAML1 mastermind-like 1 (Drosophila)
MAP2K2 mitogen-activated protein kinase kinase 2
MDH1 malate dehydrogenase 1, NAD (soluble)
METAP1 methionyl aminopeptidase 1
MFAP1 microfibrillar-associated protein 1
MORF4L2 mortality factor 4 like 2
MPV17 MpV17 mitochondrial inner membrane protein
MRPL3 mitochondrial ribosomal protein L3
MRPL9 mitochondrial ribosomal protein L9
MRPS18B mitochondrial ribosomal protein S18B
MSH2 mutS homolog 2
MTA1 metastasis associated 1
MTDH metadherin
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MYL12B myosin, light chain 12B, regulatory
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NHP2 NHP2 ribonucleoprotein
NME1 NME/NM23 nucleoside diphosphate kinase 1
NONO non-POU domain containing, octamer-binding
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUDC nudC nuclear distribution protein
PARK7 parkinson protein 7
PCNA proliferating cell nuclear antigen
PDCD6 programmed cell death 6
PDHB pyruvate dehydrogenase (lipoamide) beta
PGRMC1 progesterone receptor membrane component 1
PHB2 prohibitin 2
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRDX3 peroxiredoxin 3
PRDX4 peroxiredoxin 4
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRMT1 protein arginine methyltransferase 1
PRPF31 pre-mRNA processing factor 31
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PUF60 poly-U binding splicing factor 60KDa
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD21 RAD21 homolog (S. pombe)
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RAN RAN, member RAS oncogene family
RARS arginyl-tRNA synthetase
RBMX RNA binding motif protein, X-linked
RHEB Ras homolog enriched in brain
RPA1 replication protein A1, 70kDa
RTN4 reticulon 4
RUVBL2 RuvB-like AAA ATPase 2
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCAMP3 secretory carrier membrane protein 3
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC13 SEC13 homolog (S. cerevisiae)
SEC61G Sec61 gamma subunit
SET SET nuclear proto-oncogene
SF3B2 splicing factor 3b, subunit 2, 145kDa
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SKP1 S-phase kinase-associated protein 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMG7 SMG7 nonsense mediated mRNA decay factor
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPG small nuclear ribonucleoprotein polypeptide G
SOD1 superoxide dismutase 1, soluble
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SRP9 signal recognition particle 9kDa
SRSF1 serine/arginine-rich splicing factor 1
SRSF9 serine/arginine-rich splicing factor 9
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STOML2 stomatin (EPB72)-like 2
SUMO1 small ubiquitin-like modifier 1
SYPL1 synaptophysin-like 1
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TARDBP TAR DNA binding protein
TARS threonyl-tRNA synthetase
TBCA tubulin folding cofactor A
TBL3 transducin (beta)-like 3
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TECR trans-2,3-enoyl-CoA reductase
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM106C transmembrane protein 106C
TMEM147 transmembrane protein 147
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TPGS2 tubulin polyglutamylase complex subunit 2
TRAPPC3 trafficking protein particle complex 3
TRIM28 tripartite motif containing 28
TUFM Tu translation elongation factor, mitochondrial
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBA2 ubiquitin-like modifier activating enzyme 2
UBAP2L ubiquitin associated protein 2-like
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UNG uracil-DNA glycosylase
UQCRB ubiquinol-cytochrome c reductase binding protein
UQCRC2 ubiquinol-cytochrome c reductase core protein II
UQCRH ubiquinol-cytochrome c reductase hinge protein
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VBP1 von Hippel-Lindau binding protein 1
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
XPO7 exportin 7
XPOT exportin, tRNA
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZZZ3 zinc finger, ZZ-type containing 3