SOS1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description son of sevenless homolog 1 (Drosophila)|This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6654)
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Genes

377 genes differentially expressed following the SOS1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLFN11 schlafen family member 11 3.5664
MBLAC1 metallo-beta-lactamase domain containing 1 3.5664
ZNF467 zinc finger protein 467 3.5664
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 3.5664
UPB1 ureidopropionase, beta 3.5664
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 3.5664
MRPL53 mitochondrial ribosomal protein L53 3.5664
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 3.5664
CABS1 calcium-binding protein, spermatid-specific 1 3.5664
GJB4 gap junction protein, beta 4, 30.3kDa 3.5664
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 3.5664
CSTL1 cystatin-like 1 3.5664
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 3.5664
ADRB2 adrenoceptor beta 2, surface 3.5664
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 3.5664
MYBPHL myosin binding protein H-like 3.5664
CHADL chondroadherin-like 3.5664
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3.5664
GIP gastric inhibitory polypeptide 3.5664
GPR52 G protein-coupled receptor 52 3.5664
LIPN lipase, family member N 3.5664
SCN2A sodium channel, voltage gated, type II alpha subunit 3.5664
ALOX15 arachidonate 15-lipoxygenase 3.5664
SLC46A2 solute carrier family 46, member 2 3.5664
MAGEA2 melanoma antigen family A2 3.5664
PAX3 paired box 3 3.5664
ADAM33 ADAM metallopeptidase domain 33 3.5664
C6ORF58 chromosome 6 open reading frame 58 3.5664
ATOH7 atonal homolog 7 (Drosophila) 3.5664
MPL MPL proto-oncogene, thrombopoietin receptor 3.5664
LGALS9 lectin, galactoside-binding, soluble, 9 3.5664
MYO1A myosin IA 3.5664
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 3.5664
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 3.5664
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 3.5664
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 3.5664
LEP leptin 3.5664
FAM161B family with sequence similarity 161, member B 3.5664
CYSRT1 cysteine-rich tail protein 1 3.5664
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 3.5664
MUC20 mucin 20, cell surface associated 3.5664
DMRTC1B DMRT-like family C1B 3.5664
MSC musculin 3.5664
ASB14 ankyrin repeat and SOCS box containing 14 3.5664
SFXN3 sideroflexin 3 3.5664
REN renin 3.5664
CXCL2 chemokine (C-X-C motif) ligand 2 3.5664
HAS1 hyaluronan synthase 1 3.5664
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 3.5664
C9ORF152 chromosome 9 open reading frame 152 3.5664
TNS4 tensin 4 3.5664
HBZ hemoglobin, zeta 3.5664
RBP4 retinol binding protein 4, plasma 3.5664
SRL sarcalumenin 3.5664
CIMAP2 ciliary microtubule associated protein 2 3.5664
SMIM38 small integral membrane protein 38 3.5664
ERVW-1 endogenous retrovirus group W, member 1 3.5664
PLG plasminogen 3.5664
PTH1R parathyroid hormone 1 receptor 3.5664
OTOF otoferlin 3.5664
AVPR1A arginine vasopressin receptor 1A 3.5664
TMIGD1 transmembrane and immunoglobulin domain containing 1 3.5664
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 3.5664
LMNTD1 lamin tail domain containing 1 3.5664
IGSF22 immunoglobulin superfamily, member 22 3.5664
PAPOLB poly(A) polymerase beta (testis specific) 3.5664
CLXN calaxin 3.5664
CALHM5 calcium homeostasis modulator family member 5 3.5664
SPDYE8 speedy/RINGO cell cycle regulator family member E8 3.5664
TBC1D3I TBC1 domain family member 3I 3.5664
CPNE8-AS1 CPNE8 antisense RNA 1 3.5664
C17ORF114 chromosome 17 open reading frame 114 3.5664
MDFIC2 MyoD family inhibitor domain containing 2 3.5664
GNG5B G protein subunit gamma 5B 3.5664
GREP1 glycine rich extracellular protein 1 3.5664
H3C14 H3 clustered histone 14 3.5664
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 3.5664
VXN vexin 3.5664
CCDC187 coiled-coil domain containing 187 3.5664
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 3.5664
MYL10 myosin, light chain 10, regulatory 3.5664
LY6K lymphocyte antigen 6 complex, locus K 3.5664
ZIC4 Zic family member 4 3.5664
NPIPB9 nuclear pore complex interacting protein family, member B9 3.5664
HEMK1 HemK methyltransferase family member 1 3.5664
CBLN3 cerebellin 3 precursor 3.5664
ANXA13 annexin A13 3.5664
OLAH oleoyl-ACP hydrolase 3.5664
WNT11 wingless-type MMTV integration site family, member 11 3.5664
CCR6 chemokine (C-C motif) receptor 6 3.5664
ERVFRD-1 endogenous retrovirus group FRD, member 1 3.5664
CCDC17 coiled-coil domain containing 17 3.5664
RHOXF2 Rhox homeobox family, member 2 3.5664
TLR1 toll-like receptor 1 3.5664
LEF1 lymphoid enhancer-binding factor 1 3.5664
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 3.5664
SYT15 synaptotagmin XV 3.5664
CNTN6 contactin 6 3.5664
NPIPB7 nuclear pore complex interacting protein family, member B7 3.5664
ZAR1L zygote arrest 1-like 3.5664
SAMD11 sterile alpha motif domain containing 11 3.5664
C3 complement component 3 3.5664
TACR2 tachykinin receptor 2 3.5664
CCR3 chemokine (C-C motif) receptor 3 3.5664
GJD3 gap junction protein, delta 3, 31.9kDa 3.5664
NELFCD negative elongation factor complex member C/D 3.5664
LOX lysyl oxidase 3.5664
CORIN corin, serine peptidase 3.5664
GFI1B growth factor independent 1B transcription repressor 3.5664
GML glycosylphosphatidylinositol anchored molecule like 3.5664
OLFML1 olfactomedin-like 1 3.5664
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 3.5664
CDH10 cadherin 10, type 2 (T2-cadherin) 3.5664
CLEC4C C-type lectin domain family 4, member C 3.5664
TRIM55 tripartite motif containing 55 3.5664
DRD2 dopamine receptor D2 3.5664
ISL1 ISL LIM homeobox 1 3.5664
COMP cartilage oligomeric matrix protein 3.5664
KLK15 kallikrein-related peptidase 15 3.5664
ERICH6B glutamate-rich 6B 3.5664
BPIFB1 BPI fold containing family B, member 1 3.5664
CTF1 cardiotrophin 1 3.5664
AKR1B15 aldo-keto reductase family 1, member B15 3.5664
SHOX2 short stature homeobox 2 3.5664
LCNL1 lipocalin-like 1 3.5664
CLDN34 claudin 34 3.5664
UBQLNL ubiquilin-like 3.5664
OTC ornithine carbamoyltransferase 3.5664
THTPA thiamine triphosphatase 3.5664
NOX3 NADPH oxidase 3 3.5664
HCK HCK proto-oncogene, Src family tyrosine kinase 3.5664
ILDR2 immunoglobulin-like domain containing receptor 2 3.5664
HLA-DOB major histocompatibility complex, class II, DO beta 3.5664
FAIM2 Fas apoptotic inhibitory molecule 2 3.5664
ERVV-1 endogenous retrovirus group V, member 1 3.5664
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 3.5664
ADCY4 adenylate cyclase 4 3.5664
IL25 interleukin 25 3.5664
PCDH20 protocadherin 20 3.5664
CNR2 cannabinoid receptor 2 (macrophage) 3.5664
GBX1 gastrulation brain homeobox 1 3.5664
WNT4 wingless-type MMTV integration site family, member 4 3.5664
CCDC78 coiled-coil domain containing 78 3.5664
C1ORF105 chromosome 1 open reading frame 105 3.5664
EFCC1 EF-hand and coiled-coil domain containing 1 3.5664
GPR12 G protein-coupled receptor 12 3.5664
ITGB7 integrin, beta 7 3.5664
PIP prolactin-induced protein 3.5664
NOTCH4 notch 4 3.5664
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.5664
GPR62 G protein-coupled receptor 62 3.5664
PLCD4 phospholipase C, delta 4 3.5664
GPHA2 glycoprotein hormone alpha 2 3.5664
CSF1R colony stimulating factor 1 receptor 3.5664
HMGB4 high mobility group box 4 3.5664
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 3.5664
TMPRSS12 transmembrane (C-terminal) protease, serine 12 3.5664
PADI6 peptidyl arginine deiminase, type VI 3.5664
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 3.5664
XCR1 chemokine (C motif) receptor 1 3.5664
SDSL serine dehydratase-like 3.5664
TGM1 transglutaminase 1 3.5664
FZD1 frizzled class receptor 1 3.5664
TMIGD3 transmembrane and immunoglobulin domain containing 3 3.5664
SUN3 Sad1 and UNC84 domain containing 3 3.5664
TRAM1L1 translocation associated membrane protein 1-like 1 3.5664
PLGLB1 plasminogen-like B1 3.5664
TTC34 tetratricopeptide repeat domain 34 3.5664
TTC36 tetratricopeptide repeat domain 36 3.5664
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 3.5664
TMPRSS13 transmembrane protease, serine 13 3.5664
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 3.5664
NGFR nerve growth factor receptor 3.5664
MYOZ2 myozenin 2 3.5664
CHRDL2 chordin-like 2 3.5664
EBF3 early B-cell factor 3 3.5664
ACOX2 acyl-CoA oxidase 2, branched chain 3.5664
TTBK1 tau tubulin kinase 1 3.5664
ZNF648 zinc finger protein 648 3.5664
APOD apolipoprotein D 3.5664
ZNF365 zinc finger protein 365 3.5664
ZMYND10 zinc finger, MYND-type containing 10 3.5664
KRT15 keratin 15, type I 3.5664
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 3.48857
PXYLP1 2-phosphoxylose phosphatase 1 3.46442
FEZF1 FEZ family zinc finger 1 3.19105
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 3.14162
LRRC47 leucine rich repeat containing 47 3.03759
HPN hepsin 3.03759
MED12L mediator complex subunit 12-like 2.98807
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 2.98788
DHCR24 24-dehydrocholesterol reductase 2.93467
FBXL2 F-box and leucine-rich repeat protein 2 2.91936
BCAM basal cell adhesion molecule (Lutheran blood group) 2.85643
ACOXL acyl-CoA oxidase-like 2.83827
EGFR epidermal growth factor receptor 2.81616
PFN2 profilin 2 2.80892
MFN1 mitofusin 1 2.79213
BZW1 basic leucine zipper and W2 domains 1 2.70791
COPS5 COP9 signalosome subunit 5 2.68896
EFNA2 ephrin-A2 2.63348
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.58173
CABLES1 Cdk5 and Abl enzyme substrate 1 2.56428
SLC68A1 solute carrier family 68 member 1 2.55367
CCDC47 coiled-coil domain containing 47 2.53949
PBK PDZ binding kinase 2.51213
CC2D2B coiled-coil and C2 domain containing 2B 2.5075
TLK2 tousled-like kinase 2 2.48887
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 2.4706
TBC1D12 TBC1 domain family, member 12 2.45051
NEMP1 nuclear envelope integral membrane protein 1 2.44744
TMEM140 transmembrane protein 140 2.42449
CENPO centromere protein O 2.40833
SNRPA small nuclear ribonucleoprotein polypeptide A 2.37702
AP5M1 adaptor-related protein complex 5, mu 1 subunit 2.36915
CFAP61 cilia and flagella associated protein 61 2.3307
TCEANC transcription elongation factor A (SII) N-terminal and central domain containing 2.30642
MDP1 magnesium-dependent phosphatase 1 2.3034
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 2.2925
NFXL1 nuclear transcription factor, X-box binding-like 1 2.25782
SNRK SNF related kinase 2.25686
MGA MGA, MAX dimerization protein 2.25178
WDR48 WD repeat domain 48 2.24665
KLHL18 kelch-like family member 18 2.21432
SCAF11 SR-related CTD-associated factor 11 2.1954
METTL14 methyltransferase like 14 2.19121
TCL1A T-cell leukemia/lymphoma 1A 2.19118
CGNL1 cingulin-like 1 2.183
OXCT1 3-oxoacid CoA transferase 1 2.17958
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.17315
AHCY adenosylhomocysteinase 2.17315
CD72 CD72 molecule 2.15729
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 2.15357
MKRN2 makorin ring finger protein 2 2.15071
PCSK5 proprotein convertase subtilisin/kexin type 5 2.12026
EPHA7 EPH receptor A7 2.11707
ADD1 adducin 1 (alpha) 2.10607
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 2.09789
KIF16B kinesin family member 16B 2.08577
DNASE2 deoxyribonuclease II, lysosomal 2.07586
C1D C1D nuclear receptor corepressor 2.05107
KRIT1 KRIT1, ankyrin repeat containing 2.04708
MED14 mediator complex subunit 14 2.04308
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 2.04089
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.04089
CDYL2 chromodomain protein, Y-like 2 2.03074
H2AC12 H2A clustered histone 12 2.02551
RNF180 ring finger protein 180 2.02551
RXFP1 relaxin/insulin-like family peptide receptor 1 2.02505
UBXN11 UBX domain protein 11 2.02505
SETD3 SET domain containing 3 2.02274
ABI2 abl-interactor 2 2.01199
ESYT3 extended synaptotagmin-like protein 3 2.00647

decreased expression

Symbol Name Standardized Value
DRICH1 aspartate-rich 1 -3.5664
SCN7A sodium channel, voltage gated, type VII alpha subunit -3.5664
SGK2 serum/glucocorticoid regulated kinase 2 -3.5664
TMEM81 transmembrane protein 81 -3.5664
WNT5A wingless-type MMTV integration site family, member 5A -3.5664
NPY neuropeptide Y -3.5664
AHSG alpha-2-HS-glycoprotein -3.5664
CFAP52 cilia and flagella associated protein 52 -3.5664
TRPM8 transient receptor potential cation channel, subfamily M, member 8 -3.5664
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 -3.5664
ZNF600 zinc finger protein 600 -3.5664
POM121L2 POM121 transmembrane nucleoporin-like 2 -3.5664
OAF OAF homolog (Drosophila) -3.5664
GHRHR growth hormone releasing hormone receptor -3.5664
TINCR tissue differentiation-inducing non-protein coding RNA -3.5664
TMPRSS11F transmembrane protease, serine 11F -3.5664
FPR3 formyl peptide receptor 3 -3.5664
KCNRG potassium channel regulator -3.5664
PCDHA5 protocadherin alpha 5 -3.5664
CBLN1 cerebellin 1 precursor -3.5664
ATP8B4 ATPase, class I, type 8B, member 4 -3.5664
GNRHR gonadotropin-releasing hormone receptor -3.5664
HYPK huntingtin interacting protein K -3.5664
SPMAP2L sperm microtubule associated protein 2 like -3.5664
NR4A3 nuclear receptor subfamily 4, group A, member 3 -3.5664
DUSP9 dual specificity phosphatase 9 -3.5664
ZNF471 zinc finger protein 471 -3.5664
CXCR4 chemokine (C-X-C motif) receptor 4 -3.5664
TMEM255A transmembrane protein 255A -3.5664
ADAM8 ADAM metallopeptidase domain 8 -3.5664
LMX1B LIM homeobox transcription factor 1, beta -3.5664
SPATA45 spermatogenesis associated 45 -3.5664
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 -3.5664
CCDC88B coiled-coil domain containing 88B -3.5664
LDB3 LIM domain binding 3 -3.5664
CPEB2 cytoplasmic polyadenylation element binding protein 2 -3.5664
PANK4 pantothenate kinase 4 -3.5664
MEIS2 Meis homeobox 2 -3.5664
CALM1 calmodulin 1 (phosphorylase kinase, delta) -3.45115
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C -3.4187
CD82 CD82 molecule -3.4187
ZNF768 zinc finger protein 768 -3.41402
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -3.36647
CFL1 cofilin 1 (non-muscle) -3.35015
PLXDC2 plexin domain containing 2 -3.27289
FAT3 FAT atypical cadherin 3 -3.20094
MN1 meningioma (disrupted in balanced translocation) 1 -3.18727
TOM1L2 target of myb1-like 2 (chicken) -3.14828
MDH1 malate dehydrogenase 1, NAD (soluble) -3.0973
SOS1 son of sevenless homolog 1 (Drosophila) -3.02162
CCNA2 cyclin A2 -3.01422
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 -2.98926
PHF11 PHD finger protein 11 -2.95274
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -2.88717
ZNF823 zinc finger protein 823 -2.88202
REL v-rel avian reticuloendotheliosis viral oncogene homolog -2.85073
FZD4 frizzled class receptor 4 -2.82715
ACP1 acid phosphatase 1, soluble -2.82436
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.78551
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) -2.78402
COPS9 COP9 signalosome subunit 9 -2.73235
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -2.71431
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -2.71266
PFN1 profilin 1 -2.70863
PAIP2B poly(A) binding protein interacting protein 2B -2.6851
DCAF6 DDB1 and CUL4 associated factor 6 -2.64717
MAP1S microtubule-associated protein 1S -2.63598
FBLN5 fibulin 5 -2.56712
ZNF233 zinc finger protein 233 -2.56712
SLC39A10 solute carrier family 39 (zinc transporter), member 10 -2.56696
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -2.56645
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -2.55966
MON1A MON1 secretory trafficking family member A -2.54851
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -2.4889
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.47667
PPARG peroxisome proliferator-activated receptor gamma -2.4706
ZC3HC1 zinc finger, C3HC-type containing 1 -2.4706
STX1A syntaxin 1A (brain) -2.43292
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -2.43292
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like -2.43292
NUF2 NUF2, NDC80 kinetochore complex component -2.4222
FYB2 FYN binding protein 2 -2.39907
SLC49A3 solute carrier family 49 member 3 -2.39907
RNF113A ring finger protein 113A -2.38855
SNORC secondary ossification center associated regulator of chondrocyte maturation -2.37702
TYMP thymidine phosphorylase -2.37702
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -2.37702
STAC3 SH3 and cysteine rich domain 3 -2.37702
PTPRN protein tyrosine phosphatase, receptor type, N -2.37702
BTBD17 BTB (POZ) domain containing 17 -2.36961
AGBL2 ATP/GTP binding protein-like 2 -2.36961
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -2.36961
NPIPB6 nuclear pore complex interacting protein family, member B6 -2.36961
DPY19L2 dpy-19-like 2 (C. elegans) -2.3508
VEZF1 vascular endothelial zinc finger 1 -2.31499
NCAN neurocan -2.29825
SP140 SP140 nuclear body protein -2.2925
GCNA germ cell nuclear acidic peptidase -2.2925
CALR calreticulin -2.27396
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 -2.27078
NDN necdin, melanoma antigen (MAGE) family member -2.26552
RHEB Ras homolog enriched in brain -2.26179
KRT18 keratin 18, type I -2.24665
CCDC124 coiled-coil domain containing 124 -2.22633
PACS2 phosphofurin acidic cluster sorting protein 2 -2.1954
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma -2.18039
SNX14 sorting nexin 14 -2.17657
ECSIT ECSIT signalling integrator -2.16616
TSACC TSSK6 activating co-chaperone -2.15746
PTCHD4 patched domain containing 4 -2.15224
ERP29 endoplasmic reticulum protein 29 -2.14898
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -2.13815
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 -2.12737
RHBDF2 rhomboid 5 homolog 2 (Drosophila) -2.12241
ETNK1 ethanolamine kinase 1 -2.09433
RTN2 reticulon 2 -2.07604
IFITM1 interferon induced transmembrane protein 1 -2.07475
ARMC3 armadillo repeat containing 3 -2.06065
SLC66A1 solute carrier family 66 member 1 -2.05088
MED18 mediator complex subunit 18 -2.03468
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -2.03045
SAMD3 sterile alpha motif domain containing 3 -2.02551
CLTA clathrin, light chain A -2.01982
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -2.01021