SOS1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description son of sevenless homolog 1 (Drosophila)|This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6654)
External Link http://www.ncbi.nlm.nih.gov/gene/6654
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Genes

648 interacting proteins for SOS1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABI1 abl-interactor 1
ABI2 abl-interactor 2
ABI3 ABI family, member 3
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABLIM1 actin binding LIM protein 1
ABLIM3 actin binding LIM protein family, member 3
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAP1 ArfGAP with dual PH domains 1
AGER advanced glycosylation end product-specific receptor
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANXA2 annexin A2
ANXA6 annexin A6
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APC adenomatous polyposis coli
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARF6 ADP-ribosylation factor 6
ARHGAP12 Rho GTPase activating protein 12
ARHGAP20 Rho GTPase activating protein 20
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATAD3A ATPase family, AAA domain containing 3A
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
AXL AXL receptor tyrosine kinase
B2M beta-2-microglobulin
BAIAP2 BAI1-associated protein 2
BCAR1 breast cancer anti-estrogen resistance 1
BCLAF1 BCL2-associated transcription factor 1
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BIN1 bridging integrator 1
BLK BLK proto-oncogene, Src family tyrosine kinase
BLNK B-cell linker
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTC betacellulin
BTK Bruton agammaglobulinemia tyrosine kinase
C11ORF84 chromosome 11 open reading frame 84
C1ORF27 chromosome 1 open reading frame 27
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPZB capping protein (actin filament) muscle Z-line, beta
CASS4 Cas scaffolding protein family member 4
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBR1 carbonyl reductase 1
CCM2L cerebral cavernous malformation 2-like
CD19 CD19 molecule
CD247 CD247 molecule
CD28 CD28 molecule
CD2AP CD2-associated protein
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD59 CD59 molecule, complement regulatory protein
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CD86 CD86 molecule
CDC37 cell division cycle 37
CDC42 cell division cycle 42
CFL1 cofilin 1 (non-muscle)
CFL2 cofilin 2 (muscle)
CHMP3 charged multivesicular body protein 3
CNTRL centriolin
CORO1B coronin, actin binding protein, 1B
CORO1C coronin, actin binding protein, 1C
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF1R colony stimulating factor 1 receptor
CSK c-src tyrosine kinase
CSRP1 cysteine and glycine-rich protein 1
CTTN cortactin
CUX1 cut-like homeobox 1
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYTH1 cytohesin 1
CYTH2 cytohesin 2
CYTH3 cytohesin 3
DAPK3 death-associated protein kinase 3
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBN1 drebrin 1
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIAPH1 diaphanous-related formin 1
DLD dihydrolipoamide dehydrogenase
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNM1 dynamin 1
DNM2 dynamin 2
DNM3 dynamin 3
DOCK4 dedicator of cytokinesis 4
DOCK5 dedicator of cytokinesis 5
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DST dystonin
DUT deoxyuridine triphosphatase
DYNLL1 dynein, light chain, LC8-type 1
EDC4 enhancer of mRNA decapping 4
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1G eukaryotic translation elongation factor 1 gamma
EEF2 eukaryotic translation elongation factor 2
EFNA1 ephrin-A1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4A3 eukaryotic translation initiation factor 4A3
ELMO2 engulfment and cell motility 2
EPHA2 EPH receptor A2
EPO erythropoietin
EPOR erythropoietin receptor
EPPK1 epiplakin 1
EPS15 epidermal growth factor receptor pathway substrate 15
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR1OP FGFR1 oncogene partner
FGFR1OP2 FGFR1 oncogene partner 2
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGR FGR proto-oncogene, Src family tyrosine kinase
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FLNB filamin B, beta
FLT4 fms-related tyrosine kinase 4
FRS2 fibroblast growth factor receptor substrate 2
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAREM GRB2 associated, regulator of MAPK1
GAREML GRB2 associated, regulator of MAPK1-like
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMFB glia maturation factor, beta
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
GRWD1 glutamate-rich WD repeat containing 1
GSN gelsolin
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
HACD3 3-hydroxyacyl-CoA dehydratase 3
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HBEGF heparin-binding EGF-like growth factor
HCK HCK proto-oncogene, Src family tyrosine kinase
HDLBP high density lipoprotein binding protein
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIST1H2BH histone cluster 1, H2bh
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HLA-E major histocompatibility complex, class I, E
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTRA1 HtrA serine peptidase 1
HUNK hormonally up-regulated Neu-associated kinase
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGHD immunoglobulin heavy constant delta
IGHE immunoglobulin heavy constant epsilon
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker)
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker)
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL11 interleukin 11
IL11RA interleukin 11 receptor, alpha
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL2 interleukin 2
IL20RA interleukin 20 receptor, alpha
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL3RA interleukin 3 receptor, alpha (low affinity)
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL9 interleukin 9
ILF3 interleukin enhancer binding factor 3, 90kDa
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
INPPL1 inositol polyphosphate phosphatase-like 1
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
ITK IL2-inducible T-cell kinase
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN1 intersectin 1 (SH3 domain protein)
ITSN2 intersectin 2
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KDR kinase insert domain receptor
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIRREL kin of IRRE like (Drosophila)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KL klotho
KLB klotho beta
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIMA1 LIM domain and actin binding 1
LMNA lamin A/C
LMO4 LIM domain only 4
LMO7 LIM domain 7
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LRRK1 leucine-rich repeat kinase 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
LUZP1 leucine zipper protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MATR3 matrin 3
MET MET proto-oncogene, receptor tyrosine kinase
MPRIP myosin phosphatase Rho interacting protein
MRAS muscle RAS oncogene homolog
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC20 mucin 20, cell surface associated
MYCBP MYC binding protein
MYH10 myosin, heavy chain 10, non-muscle
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO18A myosin XVIIIA
MYO1A myosin IA
MYO1B myosin IB
MYO1C myosin IC
MYO1D myosin ID
MYO3B myosin IIIB
MYO6 myosin VI
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKAP1 NCK-associated protein 1
NEB nebulin
NEXN nexilin (F actin binding protein)
NF2 neurofibromin 2 (merlin)
NGF nerve growth factor (beta polypeptide)
NISCH nischarin
NONO non-POU domain containing, octamer-binding
NOSTRIN nitric oxide synthase trafficking
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRF1 nuclear respiratory factor 1
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG3 neuregulin 3
NRG4 neuregulin 4
NTF3 neurotrophin 3
NTF4 neurotrophin 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUCLEOLIN nucleolin multifunctional protein
PABPC1 poly(A) binding protein, cytoplasmic 1
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAWR PRKC, apoptosis, WT1, regulator
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDCD6 programmed cell death 6
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPK1 3-phosphoinositide dependent protein kinase 1
PELP1 proline, glutamate and leucine rich protein 1
PHGDH phosphoglycerate dehydrogenase
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PKM pyruvate kinase, muscle
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLEC plectin
PLS3 plastin 3
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP5C protein phosphatase 5, catalytic subunit
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRDX1 peroxiredoxin 1
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT5 protein arginine methyltransferase 5
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB11B RAB11B, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RACGAP1 Rac GTPase activating protein 1
RADIL Ras association and DIL domains
RAI14 retinoic acid induced 14
RANBP9 RAN binding protein 9
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RBBP6 retinoblastoma binding protein 6
RBBP7 retinoblastoma binding protein 7
RCC2 regulator of chromosome condensation 2
RERG RAS-like, estrogen-regulated, growth inhibitor
RET ret proto-oncogene
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RHOC ras homolog family member C
RHOD ras homolog family member D
RHOF ras homolog family member F (in filopodia)
RHOG ras homolog family member G
RHOH ras homolog family member H
RHOJ ras homolog family member J
RHOQ ras homolog family member Q
RHOT1 ras homolog family member T1
RHOT2 ras homolog family member T2
RHOU ras homolog family member U
RHOV ras homolog family member V
RIT2 Ras-like without CAAX 2
RPL10 ribosomal protein L10
RPL12 ribosomal protein L12
RPL18 ribosomal protein L18
RPL18A ribosomal protein L18a
RPL21 ribosomal protein L21
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL35A ribosomal protein L35a
RPL36 ribosomal protein L36
RPL4 ribosomal protein L4
RPL7 ribosomal protein L7
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS18 ribosomal protein S18
RPS20 ribosomal protein S20
RPS23 ribosomal protein S23
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS28 ribosomal protein S28
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS5 ribosomal protein S5
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
S100A6 S100 calcium binding protein A6
SAFB2 scaffold attachment factor B2
SCIN scinderin
SEC16A SEC16 homolog A (S. cerevisiae)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SGK1 serum/glucocorticoid regulated kinase 1
SGMS1 sphingomyelin synthase 1
SH2D2A SH2 domain containing 2A
SH2D5 SH2 domain containing 5
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SH3KBP1 SH3-domain kinase binding protein 1
SH3PXD2A SH3 and PX domains 2A
SH3PXD2B SH3 and PX domains 2B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SIRPA signal-regulatory protein alpha
SLA2 Src-like-adaptor 2
SLAIN2 SLAIN motif family, member 2
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNX18 sorting nexin 18
SNX9 sorting nexin 9
SORBS1 sorbin and SH3 domain containing 1
SOS2 son of sevenless homolog 2 (Drosophila)
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPRY3 sprouty homolog 3 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SPTA1 spectrin, alpha, erythrocytic 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRRM1 serine/arginine repetitive matrix 1
SRSF10 serine/arginine-rich splicing factor 10
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAMBP STAM binding protein
SVIL supervillin
SYK spleen tyrosine kinase
SYNJ1 synaptojanin 1
SYNPO synaptopodin
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK2 TAO kinase 2
TEC tec protein tyrosine kinase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THRAP3 thyroid hormone receptor associated protein 3
TIAF1 TGFB1-induced anti-apoptotic factor 1
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNIK TRAF2 and NCK interacting kinase
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TRAT1 T cell receptor associated transmembrane adaptor 1
TREM2 triggering receptor expressed on myeloid cells 2
TRIM24 tripartite motif containing 24
TSG101 tumor susceptibility 101
TTBK2 tau tubulin kinase 2
TTYH2 tweety family member 2
TUBA1B tubulin, alpha 1b
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
TUFM Tu translation elongation factor, mitochondrial
TXK TXK tyrosine kinase
TYROBP TYRO protein tyrosine kinase binding protein
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBASH3A ubiquitin associated and SH3 domain containing A
UBASH3B ubiquitin associated and SH3 domain containing B
UBB ubiquitin B
UBC ubiquitin C
UGCG UDP-glucose ceramide glucosyltransferase
UGDH UDP-glucose 6-dehydrogenase
USP9X ubiquitin specific peptidase 9, X-linked
USP9Y ubiquitin specific peptidase 9, Y-linked
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WASF3 WAS protein family, member 3
WASL Wiskott-Aldrich syndrome-like
WDR1 WD repeat domain 1
WDR44 WD repeat domain 44
WDR6 WD repeat domain 6
WDR77 WD repeat domain 77
WIPF1 WAS/WASL interacting protein family, member 1
WIPF2 WAS/WASL interacting protein family, member 2
WIPF3 WAS/WASL interacting protein family, member 3
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFYVE28 zinc finger, FYVE domain containing 28
ZMYM2 zinc finger, MYM-type 2