SOX10 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description SRY (sex determining region Y)-box 10|This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6663)
External Link https://ncbi.nlm.nih.gov/gene/6663
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Genes

498 genes differentially expressed following the SOX10 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center 0.0154684
CXCL12 chemokine (C-X-C motif) ligand 12 0.0118541
CXCL8 chemokine (C-X-C motif) ligand 8 0.0110351
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.010816
PEG3 paternally expressed 3 0.0107955
MBD1 methyl-CpG binding domain protein 1 0.0107392
CLC Charcot-Leyden crystal galectin 0.0105911
S100A7 S100 calcium binding protein A7 0.0104401
PLAT plasminogen activator, tissue 0.0101914
JMJD6 jumonji domain containing 6 0.0101412
HSPA8 heat shock 70kDa protein 8 0.00959959
STK10 serine/threonine kinase 10 0.00947793
LGALS13 lectin, galactoside-binding, soluble, 13 0.00936105
S100P S100 calcium binding protein P 0.00933555
MRPS16 mitochondrial ribosomal protein S16 0.00931179
CCN2 cellular communication network factor 2 0.00927227
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00921549
SYNM synemin, intermediate filament protein 0.00921076
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00919142
ZDHHC6 zinc finger, DHHC-type containing 6 0.00910382
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00899483
IRS2 insulin receptor substrate 2 0.00891941
SFRP1 secreted frizzled-related protein 1 0.00888517
HMGA1 high mobility group AT-hook 1 0.0086853
ATF3 activating transcription factor 3 0.00850584
GOLGA8A golgin A8 family, member A 0.0084443
HOXC6 homeobox C6 0.00830931
DAXX death-domain associated protein 0.00822897
BASP1 brain abundant, membrane attached signal protein 1 0.00822341
SAMD4A sterile alpha motif domain containing 4A 0.00820943
ABLIM1 actin binding LIM protein 1 0.00803768
AKAP12 A kinase (PRKA) anchor protein 12 0.00801156
MPO myeloperoxidase 0.00795819
CALML5 calmodulin-like 5 0.00791532
CTSG cathepsin G 0.00783322
CLEC11A C-type lectin domain family 11, member A 0.00773622
MCAM melanoma cell adhesion molecule 0.00772555
MTUS1 microtubule associated tumor suppressor 1 0.00771364
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00767397
CDC20 cell division cycle 20 0.00766887
NVL nuclear VCP-like 0.00755376
MME membrane metallo-endopeptidase 0.0075052
SCGB2A2 secretoglobin, family 2A, member 2 0.0074745
GREM1 gremlin 1, DAN family BMP antagonist 0.00741281
CRISP3 cysteine-rich secretory protein 3 0.00740215
PI3 peptidase inhibitor 3, skin-derived 0.00727339
TUBB6 tubulin, beta 6 class V 0.00723618
DEFA4 defensin, alpha 4, corticostatin 0.0071014
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00708429
SLC43A3 solute carrier family 43, member 3 0.00700387
C7 complement component 7 0.00690056
ELANE elastase, neutrophil expressed 0.00689398
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00688537
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00687451
RUNX3 runt-related transcription factor 3 0.00682158
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00682152
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.00679973
PLK2 polo-like kinase 2 0.00676002
S100A9 S100 calcium binding protein A9 0.00674895
PDLIM5 PDZ and LIM domain 5 0.00673275
PRKCA protein kinase C, alpha 0.00671535
KRT7 keratin 7, type II 0.00671385
EGR3 early growth response 3 0.00670201
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00669823
ZC3H12A zinc finger CCCH-type containing 12A 0.00669325
GOLM1 golgi membrane protein 1 0.00668712
PPIF peptidylprolyl isomerase F 0.00667349
BTG3 BTG family, member 3 0.00660208
NPTX2 neuronal pentraxin II 0.00656017
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00653466
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00653433
CLIC5 chloride intracellular channel 5 0.0065316
LCN2 lipocalin 2 0.00650757
TFRC transferrin receptor 0.00647257
HOXB2 homeobox B2 0.00643279
MPDZ multiple PDZ domain protein 0.00642278
SLPI secretory leukocyte peptidase inhibitor 0.00636793
HBEGF heparin-binding EGF-like growth factor 0.00635793
PITX3 paired-like homeodomain 3 0.0063564
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00635401
TARP TCR gamma alternate reading frame protein 0.00632152
FABP4 fatty acid binding protein 4, adipocyte 0.00628358
GRAMD1C GRAM domain containing 1C 0.0062639
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.00622239
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00619316
C3ORF14 chromosome 3 open reading frame 14 0.00618693
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.0061055
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00608738
WT1 Wilms tumor 1 0.00608599
FBL fibrillarin 0.00606131
PDZD2 PDZ domain containing 2 0.0060558
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00604559
PDE4B phosphodiesterase 4B, cAMP-specific 0.00601304
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00600117
IFRD2 interferon-related developmental regulator 2 0.00599716
MPHOSPH8 M-phase phosphoprotein 8 0.00596455
MTA1 metastasis associated 1 0.00593608
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00587616
MAGEA3 melanoma antigen family A3 0.00585928
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00581662
AZU1 azurocidin 1 0.00576765
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00576362
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00574542
TWIST1 twist family bHLH transcription factor 1 0.00573195
VIM vimentin 0.00572049
ASCL1 achaete-scute family bHLH transcription factor 1 0.00567916
ANXA1 annexin A1 0.00567027
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.0056645
PLCE1 phospholipase C, epsilon 1 0.00565432
MATN2 matrilin 2 0.00565394
BCL2A1 BCL2-related protein A1 0.0056535
MSL1 male-specific lethal 1 homolog (Drosophila) 0.00563436
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00563202
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00562109
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00559712
PRTN3 proteinase 3 0.00558303
CXCL6 chemokine (C-X-C motif) ligand 6 0.00557728
CLGN calmegin 0.00557718
MLH1 mutL homolog 1 0.00557558
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0055725
RBM5 RNA binding motif protein 5 0.00554978
MCM2 minichromosome maintenance complex component 2 0.00552025
EXOSC8 exosome component 8 0.00551294
S100A12 S100 calcium binding protein A12 0.00550412
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00550125
CAPN2 calpain 2, (m/II) large subunit 0.00549554
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 0.0054924
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.00548307
AMIGO2 adhesion molecule with Ig-like domain 2 0.00547765
PTPRE protein tyrosine phosphatase, receptor type, E 0.00547637
NXF1 nuclear RNA export factor 1 0.00544726
C1ORF115 chromosome 1 open reading frame 115 0.00544123
MYH10 myosin, heavy chain 10, non-muscle 0.0054255
NOP56 NOP56 ribonucleoprotein 0.00541501
RGCC regulator of cell cycle 0.00541365
MCM4 minichromosome maintenance complex component 4 0.00540683
PCGF2 polycomb group ring finger 2 0.00540612
SCGB2A1 secretoglobin, family 2A, member 1 0.00539627
AHCY adenosylhomocysteinase 0.00539093
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00538718
NES nestin 0.00538588
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00537253
RPL10 ribosomal protein L10 0.00535364
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 0.00535262
MLPH melanophilin 0.00534397
SETD5 SET domain containing 5 0.0053437
LY6D lymphocyte antigen 6 complex, locus D 0.00534015
TM4SF4 transmembrane 4 L six family member 4 0.00533922
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.00533614
TFDP1 transcription factor Dp-1 0.00532934
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00532244
ANK2 ankyrin 2, neuronal 0.00529507
EDN3 endothelin 3 0.00529306
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.0052896
LAMP5 lysosomal-associated membrane protein family, member 5 0.00527616
EIF4B eukaryotic translation initiation factor 4B 0.00526323
SRSF6 serine/arginine-rich splicing factor 6 0.00525964
TNIK TRAF2 and NCK interacting kinase 0.00524363
THBS1 thrombospondin 1 0.00523852
TUFM Tu translation elongation factor, mitochondrial 0.00523533
MSLN mesothelin 0.00523167
SUSD4 sushi domain containing 4 0.00521839
WBP5 WW domain binding protein 5 0.00521709
TBX3 T-box 3 0.0051954
HOMER1 homer scaffolding protein 1 0.00518591
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.0051795
OLFML3 olfactomedin-like 3 0.00517191
CA2 carbonic anhydrase II 0.00515269
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 0.00514537
C6ORF48 chromosome 6 open reading frame 48 0.00513134
TRIP6 thyroid hormone receptor interactor 6 0.00512873
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0051286
PLAUR plasminogen activator, urokinase receptor 0.00511965
CADPS2 Ca++-dependent secretion activator 2 0.00509886
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00509578
PBX1 pre-B-cell leukemia homeobox 1 0.00507998
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00507484
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00505263
HELLS helicase, lymphoid-specific 0.00504639
HSPA2 heat shock 70kDa protein 2 0.00504109
POPDC3 popeye domain containing 3 0.00501802
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00501302
PHGDH phosphoglycerate dehydrogenase 0.00500621
TMC5 transmembrane channel-like 5 0.00500201
EIF6 eukaryotic translation initiation factor 6 0.00498663
BAMBI BMP and activin membrane-bound inhibitor 0.00498541
IER5 immediate early response 5 0.00497955
IARS1 isoleucyl-tRNA synthetase 1 0.00497237
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00496896
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.00496027
PRKD1 protein kinase D1 0.0049502
BPI bactericidal/permeability-increasing protein 0.00494988
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.0049407
NPIPA1 nuclear pore complex interacting protein family, member A1 0.00493415
TPBG trophoblast glycoprotein 0.00491411
GRAMD2B GRAM domain containing 2B 0.00490364
RRAD Ras-related associated with diabetes 0.00489984
CTNND1 catenin (cadherin-associated protein), delta 1 0.00488066
PFKM phosphofructokinase, muscle 0.00486279
CFAP20 cilia and flagella associated protein 20 0.00486122
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00485669
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00485133
VCL vinculin 0.00484417
GTSE1 G-2 and S-phase expressed 1 0.00483101
SORBS3 sorbin and SH3 domain containing 3 0.00482279
TCEAL2 transcription elongation factor A (SII)-like 2 0.0048114
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00479187
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00478867
PDE8B phosphodiesterase 8B 0.00478447
ZCCHC24 zinc finger, CCHC domain containing 24 0.00478294
CDR2L cerebellar degeneration-related protein 2-like 0.00477911
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00477229
IPP intracisternal A particle-promoted polypeptide 0.00476443
FOXL2 forkhead box L2 0.00476399
NID1 nidogen 1 0.00475486
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.00474046
NAP1L1 nucleosome assembly protein 1-like 1 0.00473956
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.0047365
RGS1 regulator of G-protein signaling 1 0.00472608
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.00470997
DLG5 discs, large homolog 5 (Drosophila) 0.0047065
ACTN1 actinin, alpha 1 0.00468185
COLEC11 collectin sub-family member 11 0.0046736
PRNP prion protein 0.00466811
NDC1 NDC1 transmembrane nucleoporin 0.00466731
KIF14 kinesin family member 14 0.00466187
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.00466071
TMCO6 transmembrane and coiled-coil domains 6 0.00465564
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00465125
LHFP lipoma HMGIC fusion partner 0.00463399
MDK midkine (neurite growth-promoting factor 2) 0.0046292
HOXB7 homeobox B7 0.00461044
AZIN1 antizyme inhibitor 1 0.00460823
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.00459983
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.00459561
KLK10 kallikrein-related peptidase 10 0.00459302
PEG10 paternally expressed 10 0.00459141
PITX1 paired-like homeodomain 1 0.00458771
TUBB2A tubulin, beta 2A class IIa 0.00458391
RBM39 RNA binding motif protein 39 0.00458217
APOD apolipoprotein D 0.00457483
MAMLD1 mastermind-like domain containing 1 0.00457187
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.0045713
MUC4 mucin 4, cell surface associated 0.00456967
ALCAM activated leukocyte cell adhesion molecule 0.00455722
MRC2 mannose receptor, C type 2 0.00451568
WWC2 WW and C2 domain containing 2 0.00450833
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 0.00450568
INAVA innate immunity activator 0.00450288

decreased expression

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0162286
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0146019
PCP4 Purkinje cell protein 4 -0.0122075
MAP7 microtubule-associated protein 7 -0.0121378
KDM5D lysine (K)-specific demethylase 5D -0.0116877
GLUL glutamate-ammonia ligase -0.0107336
TPSAB1 tryptase alpha/beta 1 -0.0103743
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0103711
FGFR3 fibroblast growth factor receptor 3 -0.0103186
AKR1C3 aldo-keto reductase family 1, member C3 -0.0101537
TXNIP thioredoxin interacting protein -0.00947857
HOPX HOP homeobox -0.009444
SEPP1 selenoprotein P, plasma, 1 -0.00910026
TGFBI transforming growth factor, beta-induced, 68kDa -0.00899295
EIF5A eukaryotic translation initiation factor 5A -0.00895617
CTSZ cathepsin Z -0.00860204
CLU clusterin -0.00858436
ADM adrenomedullin -0.00826858
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00818336
IFI6 interferon, alpha-inducible protein 6 -0.00800319
SNX10 sorting nexin 10 -0.00797932
SIRT3 sirtuin 3 -0.00793939
FUCA1 fucosidase, alpha-L- 1, tissue -0.00793651
TPD52L1 tumor protein D52-like 1 -0.00781562
IGFBP5 insulin-like growth factor binding protein 5 -0.00779777
CST3 cystatin C -0.00776361
SYNGR3 synaptogyrin 3 -0.00768046
AKR1C2 aldo-keto reductase family 1, member C2 -0.00756567
PHACTR2 phosphatase and actin regulator 2 -0.0075228
AQP1 aquaporin 1 (Colton blood group) -0.00750878
AKR1C1 aldo-keto reductase family 1, member C1 -0.00744055
SFTPA2 surfactant protein A2 -0.00741484
ZIC1 Zic family member 1 -0.00735357
IFITM1 interferon induced transmembrane protein 1 -0.00729924
FOLR1 folate receptor 1 (adult) -0.00720306
PAX6 paired box 6 -0.00705704
ELN elastin -0.00702824
BAD BCL2-associated agonist of cell death -0.00701032
HPN hepsin -0.00699792
SFTPC surfactant protein C -0.00699766
AUTS2 autism susceptibility candidate 2 -0.00687581
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.0067637
NDRG1 N-myc downstream regulated 1 -0.00676363
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.00671478
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00660323
PERP PERP, TP53 apoptosis effector -0.00656635
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00655259
DHDDS dehydrodolichyl diphosphate synthase -0.00648763
CADM1 cell adhesion molecule 1 -0.00647594
SV2B synaptic vesicle glycoprotein 2B -0.00647206
DEPTOR DEP domain containing MTOR-interacting protein -0.00644448
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0064393
AMACR alpha-methylacyl-CoA racemase -0.00640964
RNF43 ring finger protein 43 -0.00640778
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00636367
COMMD8 COMM domain containing 8 -0.00635641
IGFBP6 insulin-like growth factor binding protein 6 -0.00634662
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00629454
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00628391
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00627844
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00624211
CA12 carbonic anhydrase XII -0.00621351
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00618241
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00615552
GSTT1 glutathione S-transferase theta 1 -0.00609002
FXYD2 FXYD domain containing ion transport regulator 2 -0.00605184
SFTPB surfactant protein B -0.00604267
LRRC17 leucine rich repeat containing 17 -0.00601261
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00600719
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00599508
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00593736
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00592516
ST18 suppression of tumorigenicity 18, zinc finger -0.00592498
EREG epiregulin -0.00591722
QDPR quinoid dihydropteridine reductase -0.0059118
CD9 CD9 molecule -0.00590036
MB myoglobin -0.00588981
TMEM176A transmembrane protein 176A -0.00587439
CD99 CD99 molecule -0.00584577
METTL7A methyltransferase like 7A -0.00584447
CYBA cytochrome b-245, alpha polypeptide -0.00581981
SFTPD surfactant protein D -0.00581869
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00581119
HEBP2 heme binding protein 2 -0.00576206
STC1 stanniocalcin 1 -0.00574619
EFR3A EFR3 homolog A (S. cerevisiae) -0.00572635
ADAM28 ADAM metallopeptidase domain 28 -0.00569105
CRYL1 crystallin, lambda 1 -0.00568518
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00566559
RNF167 ring finger protein 167 -0.00566358
TMEM176B transmembrane protein 176B -0.00563473
SSBP2 single-stranded DNA binding protein 2 -0.00562925
VSNL1 visinin-like 1 -0.00561118
GCLC glutamate-cysteine ligase, catalytic subunit -0.00560609
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -0.00560274
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -0.00559687
SERINC5 serine incorporator 5 -0.005588
ANGPTL4 angiopoietin-like 4 -0.0055711
GPX3 glutathione peroxidase 3 -0.0055563
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00555395
CHMP6 charged multivesicular body protein 6 -0.00554179
DSP desmoplakin -0.00553203
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00552874
CD244 CD244 molecule, natural killer cell receptor 2B4 -0.00552673
GPX2 glutathione peroxidase 2 -0.00545339
CLEC3B C-type lectin domain family 3, member B -0.00544461
RIDA reactive intermediate imine deaminase A homolog -0.00542966
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00542902
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00540531
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00539827
CTSH cathepsin H -0.00538777
PLAGL1 pleiomorphic adenoma gene-like 1 -0.00535948
RGS17 regulator of G-protein signaling 17 -0.00530589
S100A4 S100 calcium binding protein A4 -0.00530118
FBXL5 F-box and leucine-rich repeat protein 5 -0.00530107
TATDN2 TatD DNase domain containing 2 -0.00528725
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00528607
BSG basigin (Ok blood group) -0.0052829
WDR91 WD repeat domain 91 -0.00526582
POLB polymerase (DNA directed), beta -0.00525143
MN1 meningioma (disrupted in balanced translocation) 1 -0.00525068
DCLK1 doublecortin-like kinase 1 -0.0052464
STC2 stanniocalcin 2 -0.00522315
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00520395
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00518297
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00518205
CCN3 cellular communication network factor 3 -0.00517295
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.00516088
AHR aryl hydrocarbon receptor -0.00514053
TLR2 toll-like receptor 2 -0.00513868
HDDC2 HD domain containing 2 -0.0051361
HILPDA hypoxia inducible lipid droplet-associated -0.00512674
GAS7 growth arrest-specific 7 -0.00511788
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -0.00511267
GPNMB glycoprotein (transmembrane) nmb -0.00511044
SLA Src-like-adaptor -0.00510729
IFITM2 interferon induced transmembrane protein 2 -0.00510531
RWDD1 RWD domain containing 1 -0.00509783
SNX11 sorting nexin 11 -0.00509226
CD84 CD84 molecule -0.00508229
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa -0.00507948
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -0.00506595
NOTCH3 notch 3 -0.00505945
RBPMS RNA binding protein with multiple splicing -0.0050475
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.0050245
E2F2 E2F transcription factor 2 -0.00502388
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00500136
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 -0.00498291
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.0049228
RBM47 RNA binding motif protein 47 -0.0048971
SPTSSA serine palmitoyltransferase, small subunit A -0.00489287
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00488862
KIAA0513 KIAA0513 -0.00488577
LRP2 low density lipoprotein receptor-related protein 2 -0.00488096
STK39 serine threonine kinase 39 -0.00487781
SMYD3 SET and MYND domain containing 3 -0.00485872
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.00485791
IDO1 indoleamine 2,3-dioxygenase 1 -0.0048525
NRCAM neuronal cell adhesion molecule -0.00484031
WFDC2 WAP four-disulfide core domain 2 -0.00483502
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00483255
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00483227
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase -0.0048127
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.0048036
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.0047723
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -0.00477139
NPY neuropeptide Y -0.00476855
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00476499
ARMT1 acidic residue methyltransferase 1 -0.00476388
STK38L serine/threonine kinase 38 like -0.00474527
ZNF124 zinc finger protein 124 -0.00474094
VSIG4 V-set and immunoglobulin domain containing 4 -0.00473331
MPP1 membrane protein, palmitoylated 1, 55kDa -0.00472652
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0047195
EGFL6 EGF-like-domain, multiple 6 -0.004716
FAM162A family with sequence similarity 162, member A -0.00470845
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.00470363
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00468461
ACSM5 acyl-CoA synthetase medium-chain family member 5 -0.00467496
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.0046715
CAMK1 calcium/calmodulin-dependent protein kinase I -0.00466101
NPC2 Niemann-Pick disease, type C2 -0.00464845
H1-2 H1.2 linker histone, cluster member -0.00464824
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00464529
ABHD6 abhydrolase domain containing 6 -0.00464271
IFI30 interferon, gamma-inducible protein 30 -0.00463457
RIT1 Ras-like without CAAX 1 -0.00463363
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00462794
NRN1 neuritin 1 -0.00462243
CRYM crystallin, mu -0.00461959
SEPTIN10 septin 10 -0.00461553
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -0.00460654
COMMD3 COMM domain containing 3 -0.00459071
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.00459029
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.0045797
MPC2 mitochondrial pyruvate carrier 2 -0.00457459
FRYL FRY-like -0.00457317
TRAPPC3 trafficking protein particle complex 3 -0.00457209
FAM172A family with sequence similarity 172, member A -0.00457014
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -0.00456654
NCKAP1L NCK-associated protein 1-like -0.00456015
GLRX glutaredoxin (thioltransferase) -0.00455937
TFF3 trefoil factor 3 (intestinal) -0.00455118
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00454916
CHKB choline kinase beta -0.00454619
ZNF226 zinc finger protein 226 -0.00454028
NOX1 NADPH oxidase 1 -0.00453738
ZBTB16 zinc finger and BTB domain containing 16 -0.00452477
TMEM70 transmembrane protein 70 -0.00452272
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.00450416
CNPPD1 cyclin Pas1/PHO80 domain containing 1 -0.00449679
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00449026
TTR transthyretin -0.00446734
FNBP1L formin binding protein 1-like -0.00446214
TES testin LIM domain protein -0.00446061
WASL Wiskott-Aldrich syndrome-like -0.00445849
GPI glucose-6-phosphate isomerase -0.00444394
ACTB actin, beta -0.00444127
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00443476
CPB1 carboxypeptidase B1 (tissue) -0.00442683
FKBP5 FK506 binding protein 5 -0.00442342
CCNG2 cyclin G2 -0.00442062
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00442008
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00441699
AKAP7 A kinase (PRKA) anchor protein 7 -0.00440535
C4BPA complement component 4 binding protein, alpha -0.00440144
CD1E CD1e molecule -0.00439778
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00439576
RAB8A RAB8A, member RAS oncogene family -0.00439016
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00438132
C1QB complement component 1, q subcomponent, B chain -0.00437744
BPGM 2,3-bisphosphoglycerate mutase -0.00437593
TMEM14A transmembrane protein 14A -0.00436535
SH3BP4 SH3-domain binding protein 4 -0.00436229
RAB6A RAB6A, member RAS oncogene family -0.00435765
HIST1H2BD histone cluster 1, H2bd -0.00435087
MXD4 MAX dimerization protein 4 -0.00433172
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -0.00431514
PPL periplakin -0.00430856
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.0043003
NUTF2 nuclear transport factor 2 -0.00429089
C2 complement component 2 -0.00427853
THOC7 THO complex 7 -0.00427652
COMP cartilage oligomeric matrix protein -0.00427337
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00426513
EPHB2 EPH receptor B2 -0.00425524
CST4 cystatin S -0.00425325
MSRB2 methionine sulfoxide reductase B2 -0.00425217
TSPO translocator protein (18kDa) -0.00425188