SOX10 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description SRY (sex determining region Y)-box 10|This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6663)
External Link http://www.ncbi.nlm.nih.gov/gene/6663
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31 interacting proteins for SOX10 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ALX4 ALX homeobox 4
CDK6 cyclin-dependent kinase 6
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
DLX5 distal-less homeobox 5
EGR2 early growth response 2
EPAS1 endothelial PAS domain protein 1
EXOC5 exocyst complex component 5
HHEX hematopoietically expressed homeobox
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HNF4A hepatocyte nuclear factor 4, alpha
HOXA3 homeobox A3
HOXC4 homeobox C4
JUN jun proto-oncogene
MEOX1 mesenchyme homeobox 1
NMI N-myc (and STAT) interactor
OLIG2 oligodendrocyte lineage transcription factor 2
PAX3 paired box 3
PAX6 paired box 6
POU3F2 POU class 3 homeobox 2
POU3F3 POU class 3 homeobox 3
POU5F1 POU class 5 homeobox 1
PRRX1 paired related homeobox 1
PRRX2 paired related homeobox 2
SP1 Sp1 transcription factor
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TCF12 transcription factor 12
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
UTF1 undifferentiated embryonic cell transcription factor 1