SOX13 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SRY (sex determining region Y)-box 13|This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9580)
Similar Terms
Downloads & Tools

Genes

332 genes differentially expressed following the SOX13 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC35D3 solute carrier family 35, member D3 2.93574
CCNB3 cyclin B3 2.93574
PDZD9 PDZ domain containing 9 2.93574
LMO1 LIM domain only 1 (rhombotin 1) 2.93574
LRRC55 leucine rich repeat containing 55 2.93574
PDE7B phosphodiesterase 7B 2.93574
GFAP glial fibrillary acidic protein 2.93574
ASB12 ankyrin repeat and SOCS box containing 12 2.93574
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.93574
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 2.93574
OPRL1 opiate receptor-like 1 2.93574
ECEL1 endothelin converting enzyme-like 1 2.93574
PCDHB7 protocadherin beta 7 2.93574
ZNF436 zinc finger protein 436 2.93574
FAM3D family with sequence similarity 3, member D 2.93574
SLC22A14 solute carrier family 22, member 14 2.93574
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 2.93574
SMOC1 SPARC related modular calcium binding 1 2.93574
ZACN zinc activated ligand-gated ion channel 2.93574
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 2.93574
AKAP14 A kinase (PRKA) anchor protein 14 2.93574
COLEC10 collectin sub-family member 10 (C-type lectin) 2.93574
GLUD2 glutamate dehydrogenase 2 2.93574
GPR26 G protein-coupled receptor 26 2.93574
GPR22 G protein-coupled receptor 22 2.93574
C1GALT1C1L C1GALT1-specific chaperone 1 like 2.93574
GNRHR gonadotropin-releasing hormone receptor 2.93574
RHO rhodopsin 2.93574
DIO1 deiodinase, iodothyronine, type I 2.93574
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 2.93574
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.93574
MYO1G myosin IG 2.93574
TSHZ1 teashirt zinc finger homeobox 1 2.93574
ASGR2 asialoglycoprotein receptor 2 2.93574
SPHK1 sphingosine kinase 1 2.93574
NPIPA8 nuclear pore complex interacting protein family, member A8 2.93574
DLX4 distal-less homeobox 4 2.93574
TAL2 T-cell acute lymphocytic leukemia 2 2.93574
RFPL2 ret finger protein-like 2 2.93574
SPRR1B small proline-rich protein 1B 2.93574
HSBP1L1 heat shock factor binding protein 1-like 1 2.93574
SFTPD surfactant protein D 2.93574
BSX brain-specific homeobox 2.93574
C3ORF22 chromosome 3 open reading frame 22 2.93574
TMEM217 transmembrane protein 217 2.93574
UBA7 ubiquitin-like modifier activating enzyme 7 2.93574
SMIM5 small integral membrane protein 5 2.93574
HMX3 H6 family homeobox 3 2.93574
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 2.93574
RNF227 ring finger protein 227 2.93574
RTL5 retrotransposon Gag like 5 2.93574
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) 2.93574
STYXL2 serine/threonine/tyrosine interacting like 2 2.93574
CCER2 coiled-coil glutamate-rich protein 2 2.93574
FMO2 flavin containing monooxygenase 2 (non-functional) 2.93574
PKD2L1 polycystic kidney disease 2-like 1 2.93574
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.93574
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 2.93574
SMPX small muscle protein, X-linked 2.93574
TEKTIP1 tektin bundle interacting protein 1 2.93574
CFAP157 cilia and flagella associated protein 157 2.93574
SPMAP2L sperm microtubule associated protein 2 like 2.93574
SAXO5 stabilizer of axonemal microtubules 5 2.93574
THSD8 thrombospondin type 1 domain containing 8 2.93574
ZNF606-AS1 ZNF606 antisense RNA 1 2.93574
NOTCH2NLB notch 2 N-terminal like B 2.93574
H3C13 H3 clustered histone 13 2.93574
FYB2 FYN binding protein 2 2.93574
PEAK3 PEAK family member 3 2.93574
CHCT1 CHD1 helical C-terminal domain containing 1 2.93574
CFAP68 cilia and flagella associated protein 68 2.93574
WNT16 wingless-type MMTV integration site family, member 16 2.93574
SPATA22 spermatogenesis associated 22 2.93574
MIP major intrinsic protein of lens fiber 2.93574
MYH13 myosin, heavy chain 13, skeletal muscle 2.93574
OVOL3 ovo-like zinc finger 3 2.93574
HAPLN2 hyaluronan and proteoglycan link protein 2 2.93574
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.93574
MSX1 msh homeobox 1 2.93574
GOLGA6L4 golgin A6 family-like 4 2.93574
FOSL2 FOS-like antigen 2 2.93574
SCPPPQ1 secretory calcium-binding phosphoprotein proline-glutamine rich 1 2.93574
VIT vitrin 2.93574
SH3TC1 SH3 domain and tetratricopeptide repeats 1 2.93574
C1QL3 complement component 1, q subcomponent-like 3 2.93574
OSTN osteocrin 2.93574
MLANA melan-A 2.93574
SYT15 synaptotagmin XV 2.93574
FAM107A family with sequence similarity 107, member A 2.93574
SMCP sperm mitochondria-associated cysteine-rich protein 2.93574
GDF9 growth differentiation factor 9 2.93574
PGLYRP1 peptidoglycan recognition protein 1 2.93574
CNTFR ciliary neurotrophic factor receptor 2.93574
INSRR insulin receptor-related receptor 2.93574
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.93574
PCDHB12 protocadherin beta 12 2.93574
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.93574
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.93574
CYS1 cystin 1 2.93574
SHISA8 shisa family member 8 2.93574
BCO1 beta-carotene oxygenase 1 2.93574
COMP cartilage oligomeric matrix protein 2.93574
PCDH12 protocadherin 12 2.93574
RGCC regulator of cell cycle 2.93574
EGR3 early growth response 3 2.93574
KLK6 kallikrein-related peptidase 6 2.93574
PSKH2 protein serine kinase H2 2.93574
PEBP4 phosphatidylethanolamine-binding protein 4 2.93574
APOC4 apolipoprotein C-IV 2.93574
FBXO39 F-box protein 39 2.93574
CNTF ciliary neurotrophic factor 2.93574
EDN3 endothelin 3 2.93574
FHL1 four and a half LIM domains 1 2.93574
CXCR5 chemokine (C-X-C motif) receptor 5 2.93574
CTAGE9 CTAGE family, member 9 2.93574
WFDC6 WAP four-disulfide core domain 6 2.93574
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.93574
RIPPLY2 ripply transcriptional repressor 2 2.93574
ARL13A ADP-ribosylation factor-like 13A 2.93574
NT5DC4 5'-nucleotidase domain containing 4 2.93574
NKX6-1 NK6 homeobox 1 2.93574
TSPAN19 tetraspanin 19 2.93574
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.93574
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.93574
LAMB4 laminin, beta 4 2.93574
TEX29 testis expressed 29 2.93574
TMEM255A transmembrane protein 255A 2.93574
BHLHA15 basic helix-loop-helix family, member a15 2.93574
LGALS14 lectin, galactoside-binding, soluble, 14 2.93574
MOS v-mos Moloney murine sarcoma viral oncogene homolog 2.93574
FAT2 FAT atypical cadherin 2 2.93574
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 2.93574
DLX3 distal-less homeobox 3 2.93574
PRH2 proline-rich protein HaeIII subfamily 2 2.93574
NT5C1B 5'-nucleotidase, cytosolic IB 2.93574
CTSS cathepsin S 2.93574
DAPL1 death associated protein-like 1 2.93574
SLC38A3 solute carrier family 38, member 3 2.93574
LHX5 LIM homeobox 5 2.93574
C18ORF63 chromosome 18 open reading frame 63 2.93574
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.93574
SDSL serine dehydratase-like 2.93574
TGM4 transglutaminase 4 2.93574
PDCD1 programmed cell death 1 2.93574
ZNF829 zinc finger protein 829 2.93574
SUN3 Sad1 and UNC84 domain containing 3 2.93574
NNMT nicotinamide N-methyltransferase 2.93574
GRAP2 GRB2-related adaptor protein 2 2.93574
NUTM2D NUT family member 2D 2.93574
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.93574
LAMP3 lysosomal-associated membrane protein 3 2.93574
RNF224 ring finger protein 224 2.93574
ANXA1 annexin A1 2.93574
C17ORF78 chromosome 17 open reading frame 78 2.93574
PARD3B par-3 family cell polarity regulator beta 2.93574
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.93574
OR56B1 olfactory receptor, family 56, subfamily B, member 1 2.93574
BTBD16 BTB (POZ) domain containing 16 2.93574
ASCL1 achaete-scute family bHLH transcription factor 1 2.93574
FAM199X family with sequence similarity 199, X-linked 2.93574
BOLL boule-like RNA-binding protein 2.93574
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.93574
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.91355
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.85966
MICALL2 MICAL-like 2 2.84252
EFCAB11 EF-hand calcium binding domain 11 2.77894
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 2.69604
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 2.69417
NQO2 NAD(P)H dehydrogenase, quinone 2 2.69417
GRB10 growth factor receptor-bound protein 10 2.6769
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 2.6769
MRPL49 mitochondrial ribosomal protein L49 2.64449
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.62454
TRIT1 tRNA isopentenyltransferase 1 2.6149
WDR1 WD repeat domain 1 2.61485
SNX21 sorting nexin family member 21 2.6121
PBX3 pre-B-cell leukemia homeobox 3 2.55595
BICD1 bicaudal D homolog 1 (Drosophila) 2.54542
ING1 inhibitor of growth family, member 1 2.54542
ARID3B AT rich interactive domain 3B (BRIGHT-like) 2.53659
SCARA3 scavenger receptor class A, member 3 2.51702
GET3 guided entry of tail-anchored proteins factor 3, ATPase 2.50743
DAGLA diacylglycerol lipase, alpha 2.50227
FLRT3 fibronectin leucine rich transmembrane protein 3 2.42558
UBE2C ubiquitin-conjugating enzyme E2C 2.41997
CFLAR CASP8 and FADD-like apoptosis regulator 2.41448
VSTM2A V-set and transmembrane domain containing 2A 2.4036
PTK7 protein tyrosine kinase 7 (inactive) 2.4036
MYO7A myosin VIIA 2.4036
RGS2 regulator of G-protein signaling 2 2.38199
LYRM2 LYR motif containing 2 2.35858
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 2.30077
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 2.24381
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) 2.21808
ERI1 exoribonuclease 1 2.19695
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 2.19472
TM9SF2 transmembrane 9 superfamily member 2 2.19472
ZSCAN18 zinc finger and SCAN domain containing 18 2.15956
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 2.13996
ZNF207 zinc finger protein 207 2.12176
KLF7 Kruppel-like factor 7 (ubiquitous) 2.1187
SEC23A Sec23 homolog A (S. cerevisiae) 2.11792
IGFBP4 insulin-like growth factor binding protein 4 2.11481
ENDOD1 endonuclease domain containing 1 2.10179
CYTH1 cytohesin 1 2.0962
TMEM134 transmembrane protein 134 2.09158
CCDC172 coiled-coil domain containing 172 2.08155
PCSK5 proprotein convertase subtilisin/kexin type 5 2.07396
FOXK2 forkhead box K2 2.07142
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 2.06106
GLIPR2 GLI pathogenesis-related 2 2.04586
ZNF804B zinc finger protein 804B 2.04443
TNNI3K TNNI3 interacting kinase 2.04443
BHMT betaine--homocysteine S-methyltransferase 2.04443
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.04443
FKBP1B FK506 binding protein 1B, 12.6 kDa 2.04443
RSPO2 R-spondin 2 2.04443
PPP1R3B protein phosphatase 1, regulatory subunit 3B 2.0418
SENP1 SUMO1/sentrin specific peptidase 1 2.02529
PRKCQ protein kinase C, theta 2.02529
PHF21B PHD finger protein 21B 2.01815
NRG3 neuregulin 3 2.01575
GNA14 guanine nucleotide binding protein (G protein), alpha 14 2.01497
AASS aminoadipate-semialdehyde synthase 2.01409
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 2.01025
ATP11A ATPase, class VI, type 11A 2.01025
SMIM15 small integral membrane protein 15 2.00876

decreased expression

Symbol Name Standardized Value
DYNLT3 dynein, light chain, Tctex-type 3 -2.93574
PMFBP1 polyamine modulated factor 1 binding protein 1 -2.93574
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -2.93574
PRR36 proline rich 36 -2.93574
PITPNM3 PITPNM family member 3 -2.93574
MAT1A methionine adenosyltransferase I, alpha -2.93574
TPP1 tripeptidyl peptidase I -2.93574
CLDN1 claudin 1 -2.93574
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A -2.93574
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa -2.93574
ANKRD37 ankyrin repeat domain 37 -2.93574
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.93574
SPC24 SPC24, NDC80 kinetochore complex component -2.93447
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit -2.71283
TMC8 transmembrane channel-like 8 -2.69417
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.69417
CATSPERQ catsper channel auxiliary subunit theta -2.69417
FAM181B family with sequence similarity 181, member B -2.69417
PADI3 peptidyl arginine deiminase, type III -2.69417
ZPLD1 zona pellucida-like domain containing 1 -2.69417
IRX5 iroquois homeobox 5 -2.69417
ZNF804A zinc finger protein 804A -2.69417
ACADL acyl-CoA dehydrogenase, long chain -2.69417
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 -2.69417
BHLHE40 basic helix-loop-helix family, member e40 -2.69417
LY6L lymphocyte antigen 6 family member L -2.69417
PSPN persephin -2.69417
PLN phospholamban -2.69417
NHLH1 nescient helix loop helix 1 -2.69417
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B -2.69417
GHRHR growth hormone releasing hormone receptor -2.69417
LEF1 lymphoid enhancer-binding factor 1 -2.69417
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma -2.69417
SPINK1 serine peptidase inhibitor, Kazal type 1 -2.69417
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -2.69417
IQCC IQ motif containing C -2.69417
BMP8B bone morphogenetic protein 8b -2.69417
SYTL3 synaptotagmin-like 3 -2.69417
ARHGAP20 Rho GTPase activating protein 20 -2.69417
PRPH2 peripherin 2 (retinal degeneration, slow) -2.69417
S100A16 S100 calcium binding protein A16 -2.69417
HSPA1L heat shock 70kDa protein 1-like -2.69417
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -2.69417
PCDHA13 protocadherin alpha 13 -2.69417
KLK14 kallikrein-related peptidase 14 -2.69417
COL17A1 collagen, type XVII, alpha 1 -2.69417
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 -2.69417
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -2.69417
DAW1 dynein assembly factor with WDR repeat domains 1 -2.69417
NACA2 nascent polypeptide-associated complex alpha subunit 2 -2.69417
LYPD1 LY6/PLAUR domain containing 1 -2.69417
PFN4 profilin family, member 4 -2.69417
SLC25A34 solute carrier family 25, member 34 -2.69417
PLA2G2C phospholipase A2, group IIC -2.69417
TRIM58 tripartite motif containing 58 -2.61549
SPN sialophorin -2.61549
CNGA4 cyclic nucleotide gated channel alpha 4 -2.61207
CFAP90 cilia and flagella associated protein 90 -2.61207
COL6A3 collagen, type VI, alpha 3 -2.61207
GNS glucosamine (N-acetyl)-6-sulfatase -2.61127
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase -2.57566
PRSS35 protease, serine, 35 -2.57566
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B -2.52677
RNF212B ring finger protein 212B -2.51385
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -2.50009
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -2.46614
IPO9 importin 9 -2.44587
FASTKD3 FAST kinase domains 3 -2.43897
DRC10 dynein regulatory complex subunit 10 -2.42635
VSNL1 visinin-like 1 -2.41398
SREBF1 sterol regulatory element binding transcription factor 1 -2.4036
USP3 ubiquitin specific peptidase 3 -2.40306
HEBP1 heme binding protein 1 -2.39681
MELK maternal embryonic leucine zipper kinase -2.37341
TRIP10 thyroid hormone receptor interactor 10 -2.35826
CTSA cathepsin A -2.35422
LYSET lysosomal enzyme trafficking factor -2.34842
GCLC glutamate-cysteine ligase, catalytic subunit -2.34034
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin -2.34034
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -2.33411
NME9 NME/NM23 family member 9 -2.27862
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -2.27283
RAD54L2 RAD54-like 2 (S. cerevisiae) -2.26864
RGS7BP regulator of G-protein signaling 7 binding protein -2.24232
VWA8 von Willebrand factor A domain containing 8 -2.23991
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.19472
IFT74 intraflagellar transport 74 -2.18471
ALS2 amyotrophic lateral sclerosis 2 (juvenile) -2.17041
VPS13B vacuolar protein sorting 13 homolog B (yeast) -2.16304
BANK1 B-cell scaffold protein with ankyrin repeats 1 -2.1187
ZNF287 zinc finger protein 287 -2.07837
SHANK2 SH3 and multiple ankyrin repeat domains 2 -2.07396
HSPB8 heat shock 22kDa protein 8 -2.07396
DKKL1 dickkopf-like 1 -2.07396
ABHD8 abhydrolase domain containing 8 -2.05823
SIMC1 SUMO-interacting motifs containing 1 -2.04686
MRPL9 mitochondrial ribosomal protein L9 -2.04586
SPEF2 sperm flagellar 2 -2.04443
MLKL mixed lineage kinase domain-like -2.04443
PLSCR3 phospholipid scramblase 3 -2.04443
SACK1D scaffolding CK1 anchoring protein D -2.03843
GLS2 glutaminase 2 (liver, mitochondrial) -2.01782
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 -2.01575
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 -2.00737
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.00616