SOX14 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SRY (sex determining region Y)-box 14|This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8403)
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Genes

341 genes differentially expressed following the SOX14 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PCDHA8 protocadherin alpha 8 2.99352
WNT3A wingless-type MMTV integration site family, member 3A 2.99352
OSGIN1 oxidative stress induced growth inhibitor 1 2.99352
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.99352
DUSP10 dual specificity phosphatase 10 2.99352
DUSP15 dual specificity phosphatase 15 2.99352
PROB1 proline-rich basic protein 1 2.99352
FFAR4 free fatty acid receptor 4 2.99352
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.99352
GFAP glial fibrillary acidic protein 2.99352
FGL1 fibrinogen-like 1 2.99352
HCRTR1 hypocretin (orexin) receptor 1 2.99352
IL36G interleukin 36, gamma 2.99352
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 2.99352
MEP1B meprin A, beta 2.99352
RHOXF2B Rhox homeobox family, member 2B 2.99352
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.99352
ASB15 ankyrin repeat and SOCS box containing 15 2.99352
TREM2 triggering receptor expressed on myeloid cells 2 2.99352
LRRTM1 leucine rich repeat transmembrane neuronal 1 2.99352
SPINK6 serine peptidase inhibitor, Kazal type 6 2.99352
OLFM4 olfactomedin 4 2.99352
SLC30A2 solute carrier family 30 (zinc transporter), member 2 2.99352
NEU4 sialidase 4 2.99352
ACTL7A actin-like 7A 2.99352
SPNS2 spinster homolog 2 (Drosophila) 2.99352
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.99352
LGI3 leucine-rich repeat LGI family, member 3 2.99352
LBX2 ladybird homeobox 2 2.99352
ATOH8 atonal homolog 8 (Drosophila) 2.99352
ATOH1 atonal homolog 1 (Drosophila) 2.99352
PRDM12 PR domain containing 12 2.99352
LDHC lactate dehydrogenase C 2.99352
USP50 ubiquitin specific peptidase 50 2.99352
PCDH8 protocadherin 8 2.99352
SHCBP1L SHC SH2-domain binding protein 1-like 2.99352
ADAD2 adenosine deaminase domain containing 2 2.99352
PECAM1 platelet/endothelial cell adhesion molecule 1 2.99352
FHL5 four and a half LIM domains 5 2.99352
ANKRD34A ankyrin repeat domain 34A 2.99352
C11ORF87 chromosome 11 open reading frame 87 2.99352
UBE2U ubiquitin-conjugating enzyme E2U (putative) 2.99352
ADAMTSL5 ADAMTS-like 5 2.99352
SFTPB surfactant protein B 2.99352
EFS embryonal Fyn-associated substrate 2.99352
PTGDR2 prostaglandin D2 receptor 2 2.99352
LOC107986837 uncharacterized LOC107986837 2.99352
TLE7 TLE family member 7 2.99352
ERVW-1 endogenous retrovirus group W, member 1 2.99352
ALDOB aldolase B, fructose-bisphosphate 2.99352
HBG2 hemoglobin, gamma G 2.99352
CD300LF CD300 molecule-like family member f 2.99352
ALX4 ALX homeobox 4 2.99352
VN1R2 vomeronasal 1 receptor 2 2.99352
ELOVL3 ELOVL fatty acid elongase 3 2.99352
FMO2 flavin containing monooxygenase 2 (non-functional) 2.99352
VSIR V-set immunoregulatory receptor 2.99352
HTD2 hydroxyacyl-thioester dehydratase type 2 2.99352
LRTM3 leucine rich repeat transmembrane protein 3 2.99352
SPATA31G1 SPATA31 subfamily G member 1 2.99352
SPMAP2L sperm microtubule associated protein 2 like 2.99352
NHERF4 NHERF family PDZ scaffold protein 4 2.99352
CIMAP1B ciliary microtubule associated protein 1B 2.99352
SPAAR small regulatory polypeptide of amino acid response 2.99352
GREP1 glycine rich extracellular protein 1 2.99352
H4C12 H4 clustered histone 12 2.99352
POU2AF2 POU class 2 homeobox associating factor 2 2.99352
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 2.99352
KLB klotho beta 2.99352
ACSL6 acyl-CoA synthetase long-chain family member 6 2.99352
C9 complement component 9 2.99352
BARX2 BARX homeobox 2 2.99352
FOXI2 forkhead box I2 2.99352
PIWIL3 piwi-like RNA-mediated gene silencing 3 2.99352
SCIMP SLP adaptor and CSK interacting membrane protein 2.99352
TFEC transcription factor EC 2.99352
OR2A12 olfactory receptor, family 2, subfamily A, member 12 2.99352
UROC1 urocanate hydratase 1 2.99352
PTP4A1 protein tyrosine phosphatase type IVA, member 1 2.99352
PGA3 pepsinogen 3, group I (pepsinogen A) 2.99352
FMR1NB fragile X mental retardation 1 neighbor 2.99352
PAPOLB poly(A) polymerase beta (testis specific) 2.99352
LY6H lymphocyte antigen 6 complex, locus H 2.99352
F5 coagulation factor V (proaccelerin, labile factor) 2.99352
GATA4 GATA binding protein 4 2.99352
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 2.99352
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.99352
LTK leukocyte receptor tyrosine kinase 2.99352
GPR83 G protein-coupled receptor 83 2.99352
TAS1R1 taste receptor, type 1, member 1 2.99352
CD48 CD48 molecule 2.99352
LRRC32 leucine rich repeat containing 32 2.99352
GOLGA6A golgin A6 family, member A 2.99352
WFDC8 WAP four-disulfide core domain 8 2.99352
AKNAD1 AKNA domain containing 1 2.99352
HKDC1 hexokinase domain containing 1 2.99352
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.99352
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.99352
ODF1 outer dense fiber of sperm tails 1 2.99352
C2CD4B C2 calcium-dependent domain containing 4B 2.99352
MUCL1 mucin-like 1 2.99352
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.99352
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.99352
NGB neuroglobin 2.99352
CABP7 calcium binding protein 7 2.99352
A3GALT2 alpha 1,3-galactosyltransferase 2 2.99352
CCL27 chemokine (C-C motif) ligand 27 2.99352
SHOX2 short stature homeobox 2 2.99352
CERKL ceramide kinase-like 2.99352
TNN tenascin N 2.99352
CPA2 carboxypeptidase A2 (pancreatic) 2.99352
SCML4 sex comb on midleg-like 4 (Drosophila) 2.99352
FOXE3 forkhead box E3 2.99352
MUC13 mucin 13, cell surface associated 2.99352
IL19 interleukin 19 2.99352
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.99352
ARHGAP40 Rho GTPase activating protein 40 2.99352
CCNA1 cyclin A1 2.99352
GBX1 gastrulation brain homeobox 1 2.99352
IL18RAP interleukin 18 receptor accessory protein 2.99352
TTC24 tetratricopeptide repeat domain 24 2.99352
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 2.99352
BTG4 B-cell translocation gene 4 2.99352
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.99352
LGALS14 lectin, galactoside-binding, soluble, 14 2.99352
LHX5 LIM homeobox 5 2.99352
FBXO40 F-box protein 40 2.99352
ZNF596 zinc finger protein 596 2.99352
COL9A2 collagen, type IX, alpha 2 2.99352
ANKRD55 ankyrin repeat domain 55 2.99352
NT5DC4 5'-nucleotidase domain containing 4 2.99352
DLX3 distal-less homeobox 3 2.99352
PRSS37 protease, serine, 37 2.99352
GPR62 G protein-coupled receptor 62 2.99352
IDI2 isopentenyl-diphosphate delta isomerase 2 2.99352
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.99352
MYL4 myosin, light chain 4, alkali; atrial, embryonic 2.99352
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.99352
MSLN mesothelin 2.99352
WFDC10A WAP four-disulfide core domain 10A 2.99352
CHRM4 cholinergic receptor, muscarinic 4 2.99352
PXT1 peroxisomal, testis specific 1 2.99352
IFNK interferon, kappa 2.99352
ACKR3 atypical chemokine receptor 3 2.99352
ALOX15B arachidonate 15-lipoxygenase, type B 2.99352
TMPRSS13 transmembrane protease, serine 13 2.99352
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.99352
NUTM2D NUT family member 2D 2.99352
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 2.99352
NMUR2 neuromedin U receptor 2 2.99352
EBI3 Epstein-Barr virus induced 3 2.99352
HOXB3 homeobox B3 2.99352
CD3G CD3g molecule, gamma (CD3-TCR complex) 2.99352
PITX2 paired-like homeodomain 2 2.99352
NLRP13 NLR family, pyrin domain containing 13 2.99352
LPA lipoprotein, Lp(a) 2.99352
PRAM1 PML-RARA regulated adaptor molecule 1 2.99352
HEMGN hemogen 2.99352
DHRS7C dehydrogenase/reductase (SDR family) member 7C 2.99352
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.99352
TOPAZ1 testis and ovary specific PAZ domain containing 1 2.99352
GPR50 G protein-coupled receptor 50 2.99352
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.99352
CALML6 calmodulin-like 6 2.99352
TBPL2 TATA box binding protein like 2 2.99352
ECHDC3 enoyl CoA hydratase domain containing 3 2.98227
PINK1 PTEN induced putative kinase 1 2.86976
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 2.86976
ALK anaplastic lymphoma receptor tyrosine kinase 2.8633
IL11RA interleukin 11 receptor, alpha 2.8633
NXPH4 neurexophilin 4 2.8633
TRIM44 tripartite motif containing 44 2.84057
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 2.64352
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 2.62038
CFAP144 cilia and flagella associated protein 144 2.60675
MED27 mediator complex subunit 27 2.58791
CPLX1 complexin 1 2.58751
IZUMO4 IZUMO family member 4 2.58751
POU3F2 POU class 3 homeobox 2 2.58751
TPM2 tropomyosin 2 (beta) 2.52058
SWAP70 SWAP switching B-cell complex 70kDa subunit 2.47278
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component 2.46568
TMEM225B transmembrane protein 225B 2.4221
DIPK1A divergent protein kinase domain 1A 2.39797
DYSF dysferlin 2.32986
METTL3 methyltransferase like 3 2.32431
TOGARAM1 TOG array regulator of axonemal microtubules 1 2.2954
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 2.2843
UBQLN4 ubiquilin 4 2.25132
COG7 component of oligomeric golgi complex 7 2.24971
SYNPO2 synaptopodin 2 2.2436
ITK IL2-inducible T-cell kinase 2.23115
SGO1 shugoshin 1 2.23009
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.23009
SAR1A secretion associated, Ras related GTPase 1A 2.18773
B3GLCT beta 3-glucosyltransferase 2.18682
TCEAL7 transcription elongation factor A (SII)-like 7 2.17205
CIAO2A cytosolic iron-sulfur assembly component 2A 2.15077
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 2.1175
VAMP8 vesicle-associated membrane protein 8 2.1175
ZBTB17 zinc finger and BTB domain containing 17 2.098
CREBL2 cAMP responsive element binding protein-like 2 2.0975
MED17 mediator complex subunit 17 2.0793
NHSL2 NHS-like 2 2.07198
SARS1 seryl-tRNA synthetase 1 2.06217
CCL26 chemokine (C-C motif) ligand 26 2.05786
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.04929
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 2.04291
LASP1NB LASP1 neighbor 2.035
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 2.035
CARHSP1 calcium regulated heat stable protein 1, 24kDa 2.035
ZNF630 zinc finger protein 630 2.031
EXOC8 exocyst complex component 8 2.02954
KDM8 lysine (K)-specific demethylase 8 2.02572
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.02572
PTDSS2 phosphatidylserine synthase 2 2.02259
TEAD4 TEA domain family member 4 2.01935

decreased expression

Symbol Name Standardized Value
LRRD1 leucine-rich repeats and death domain containing 1 -2.99352
ZNF575 zinc finger protein 575 -2.99352
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -2.99352
TLR5 toll-like receptor 5 -2.99352
IL17D interleukin 17D -2.99352
SYBU syntabulin (syntaxin-interacting) -2.99352
ZAN zonadhesin (gene/pseudogene) -2.99352
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled -2.99352
RTN4RL1 reticulon 4 receptor-like 1 -2.99352
TULP2 tubby like protein 2 -2.99352
CSAG3 CSAG family, member 3 -2.99352
COL11A2 collagen, type XI, alpha 2 -2.99352
PLA2G10 phospholipase A2, group X -2.99352
TACSTD2 tumor-associated calcium signal transducer 2 -2.99352
NR1I3 nuclear receptor subfamily 1, group I, member 3 -2.99352
CAPN14 calpain 14 -2.99352
INHBC inhibin, beta C -2.99352
TRIM17 tripartite motif containing 17 -2.99352
HES7 hes family bHLH transcription factor 7 -2.99352
PZP pregnancy-zone protein -2.99352
IQCJ IQ motif containing J -2.99352
RCSD1 RCSD domain containing 1 -2.99352
FAM86B2 family with sequence similarity 86, member B2 -2.99352
CIITA class II, major histocompatibility complex, transactivator -2.99352
SFXN3 sideroflexin 3 -2.99352
SPDYE1 speedy/RINGO cell cycle regulator family member E1 -2.99352
TMEM82 transmembrane protein 82 -2.99352
PDZK1 PDZ domain containing 1 -2.99352
STAB2 stabilin 2 -2.99352
SMKR1 small lysine-rich protein 1 -2.99352
TEX12 testis expressed 12 -2.99352
ALX1 ALX homeobox 1 -2.99352
KISS1 KiSS-1 metastasis-suppressor -2.99352
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 -2.99352
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 -2.99352
ZNF324B zinc finger protein 324B -2.99352
DUSP29 dual specificity phosphatase 29 -2.99352
JHY junctional cadherin complex regulator -2.99352
ZGLP1 zinc finger, GATA-like protein 1 -2.99352
IFI35 interferon-induced protein 35 -2.99352
ADAP2 ArfGAP with dual PH domains 2 -2.99352
C22ORF31 chromosome 22 open reading frame 31 -2.99352
WFDC1 WAP four-disulfide core domain 1 -2.99352
GPR18 G protein-coupled receptor 18 -2.99352
IL21R interleukin 21 receptor -2.99352
CERS3 ceramide synthase 3 -2.99352
AMIGO1 adhesion molecule with Ig-like domain 1 -2.99352
FMO1 flavin containing monooxygenase 1 -2.99352
TTC7A tetratricopeptide repeat domain 7A -2.94896
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -2.89342
PIAS1 protein inhibitor of activated STAT, 1 -2.89019
VSIG10L V-set and immunoglobulin domain containing 10 like -2.87632
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -2.86976
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like -2.8633
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -2.85385
SLITRK4 SLIT and NTRK-like family, member 4 -2.84053
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.79923
EIF3F eukaryotic translation initiation factor 3, subunit F -2.79326
RRM2B ribonucleotide reductase M2 B (TP53 inducible) -2.74093
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -2.72501
PRMT2IP PRMT2 interacting protein -2.69481
CILP2 cartilage intermediate layer protein 2 -2.5829
MTX2 metaxin 2 -2.5829
LIMD2 LIM domain containing 2 -2.56854
PPCDC phosphopantothenoylcysteine decarboxylase -2.52062
GNMT glycine N-methyltransferase -2.51048
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -2.50326
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.4845
ICA1 islet cell autoantigen 1, 69kDa -2.47813
RSKR ribosomal protein S6 kinase related -2.45344
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -2.41975
METAP1 methionyl aminopeptidase 1 -2.38229
ANO9 anoctamin 9 -2.38063
CHN2 chimerin 2 -2.36148
GALNS galactosamine (N-acetyl)-6-sulfatase -2.35133
AHCY adenosylhomocysteinase -2.32848
MYD88 myeloid differentiation primary response 88 -2.32215
PNKP polynucleotide kinase 3'-phosphatase -2.30279
GRAMD2A GRAM domain containing 2A -2.30269
BMP8A bone morphogenetic protein 8a -2.30269
COL27A1 collagen, type XXVII, alpha 1 -2.27831
PHF10 PHD finger protein 10 -2.27238
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -2.25903
DNAI1 dynein, axonemal, intermediate chain 1 -2.25903
ZC3H12A zinc finger CCCH-type containing 12A -2.25903
FHOD3 formin homology 2 domain containing 3 -2.25903
MTNAP1 mitochondrial nucleoid associated protein 1 -2.25215
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 -2.24385
SORT1 sortilin 1 -2.23009
ZNF585A zinc finger protein 585A -2.21867
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -2.19845
FGF13 fibroblast growth factor 13 -2.19796
FXR1 fragile X mental retardation, autosomal homolog 1 -2.19155
TTN titin -2.18637
RIC8B RIC8 guanine nucleotide exchange factor B -2.18417
CADM1 cell adhesion molecule 1 -2.1754
LINC02762 long intergenic non-protein coding RNA 2762 -2.14639
CDH15 cadherin 15, type 1, M-cadherin (myotubule) -2.14639
PID1 phosphotyrosine interaction domain containing 1 -2.12947
MAT2A methionine adenosyltransferase II, alpha -2.12104
CIAO3 cytosolic iron-sulfur assembly component 3 -2.098
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 -2.09164
CENPM centromere protein M -2.09153
PPP1R7 protein phosphatase 1, regulatory subunit 7 -2.08396
GOLGA6L9 golgin A6 family-like 9 -2.0793
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.07865
MBD2 methyl-CpG binding domain protein 2 -2.0697
MCOLN1 mucolipin 1 -2.05786
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -2.05029
RELT RELT tumor necrosis factor receptor -2.04929
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -2.04032
SLC46A1 solute carrier family 46 (folate transporter), member 1 -2.03705
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) -2.03705
LINGO3 leucine rich repeat and Ig domain containing 3 -2.03705
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -2.02954
KAT14 lysine acetyltransferase 14 -2.02954
SMIM10L2A small integral membrane protein 10 like 2A -2.02882
BAALC brain and acute leukemia, cytoplasmic -2.02572
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 -2.02572
DHFR2 dihydrofolate reductase 2 -2.02572
SFT2D1 SFT2 domain containing 1 -2.02259
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 -2.02259
URGCP upregulator of cell proliferation -2.01935
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.00797