SOX15 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SRY (sex determining region Y)-box 15|This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6665)
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Genes

334 genes differentially expressed following the SOX15 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CIROZ ciliated left-right organizer protein containing ZP-N domains 3.53983
CLDN9 claudin 9 3.53983
AKNAD1 AKNA domain containing 1 3.53983
SOSTDC1 sclerostin domain containing 1 3.53983
CTSF cathepsin F 3.53983
TPH1 tryptophan hydroxylase 1 3.53983
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 3.53983
GLYATL3 glycine-N-acyltransferase-like 3 3.53983
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.53983
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 3.53983
IL33 interleukin 33 3.53983
PECAM1 platelet/endothelial cell adhesion molecule 1 3.53983
LIX1 Lix1 homolog (chicken) 3.53983
LPA lipoprotein, Lp(a) 3.53983
PATE2 prostate and testis expressed 2 3.53983
BNIP5 BCL2 interacting protein 5 3.53983
LRRC8C-DT LRRC8C divergent transcript 3.53983
EVI2A ecotropic viral integration site 2A 3.53983
SFTA2 surfactant associated 2 3.53983
RBBP8NL RBBP8 N-terminal like 3.53983
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 3.53983
RGS8 regulator of G-protein signaling 8 3.53983
FGFBP2 fibroblast growth factor binding protein 2 3.53983
FMR1NB fragile X mental retardation 1 neighbor 3.53983
NR4A3 nuclear receptor subfamily 4, group A, member 3 3.53983
NYX nyctalopin 3.53983
S100A14 S100 calcium binding protein A14 3.53983
TDO2 tryptophan 2,3-dioxygenase 3.53983
PGBDF plakoglobin binding and degradation factor 3.46864
AADACL4 arylacetamide deacetylase-like 4 3.46864
OR2B2 olfactory receptor, family 2, subfamily B, member 2 3.46864
CRISP1 cysteine-rich secretory protein 1 3.46864
SSTR1 somatostatin receptor 1 3.46864
HES7 hes family bHLH transcription factor 7 3.46864
CD96 CD96 molecule 3.46864
ZACN zinc activated ligand-gated ion channel 3.46864
ENTHD1 ENTH domain containing 1 3.46864
PRELP proline/arginine-rich end leucine-rich repeat protein 3.46864
AKR1C2 aldo-keto reductase family 1, member C2 3.46864
CELA3B chymotrypsin-like elastase family, member 3B 3.46864
PLIN4 perilipin 4 3.46864
TNNI2 troponin I type 2 (skeletal, fast) 3.46864
SOX1 SRY (sex determining region Y)-box 1 3.46864
LRRC55 leucine rich repeat containing 55 3.46864
MAGED4 melanoma antigen family D4 3.46864
SOWAHB sosondowah ankyrin repeat domain family member B 3.46864
MUC22 mucin 22 3.46864
SPDYE11 speedy/RINGO cell cycle regulator family member E11 3.46864
LGI1 leucine-rich, glioma inactivated 1 3.46864
HBM hemoglobin, mu 3.46864
CRYGA crystallin, gamma A 3.46864
MMP20 matrix metallopeptidase 20 3.46864
CPB2 carboxypeptidase B2 (plasma) 3.46864
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 3.46864
RFPL3 ret finger protein-like 3 3.46864
FETUB fetuin B 3.46864
ADAMTSL5 ADAMTS-like 5 3.46864
ASB12 ankyrin repeat and SOCS box containing 12 3.46864
DIRAS3 DIRAS family, GTP-binding RAS-like 3 3.46864
PBOV1 prostate and breast cancer overexpressed 1 3.46864
SHCBP1L SHC SH2-domain binding protein 1-like 3.46864
GPR26 G protein-coupled receptor 26 3.46864
SLC23A3 solute carrier family 23, member 3 3.46864
LGALS4 lectin, galactoside-binding, soluble, 4 3.46864
MDFIC2 MyoD family inhibitor domain containing 2 3.46864
GIPC3 GIPC PDZ domain containing family, member 3 3.46864
ARX aristaless related homeobox 3.46864
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 3.46864
GPR35 G protein-coupled receptor 35 3.46864
CXCL13 chemokine (C-X-C motif) ligand 13 3.46864
FOXN4 forkhead box N4 3.46864
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 3.46864
SMPX small muscle protein, X-linked 3.46864
ASB5 ankyrin repeat and SOCS box containing 5 3.46864
STING1 stimulator of interferon response cGAMP interactor 1 3.46864
P3R3URF PIK3R3 upstream open reading frame 3.46864
CD8B2 CD8b2 molecule 3.46864
H4C14 H4 clustered histone 14 3.46864
CFAP276 cilia and flagella associated protein 276 3.46864
CPHXL cytoplasmic polyadenylated homeobox like 3.46864
CFAP107 cilia and flagella associated protein 107 3.46864
DNAAF6 dynein axonemal assembly factor 6 3.46864
CATSPERZ catsper channel auxiliary subunit zeta 3.46864
MSANTD5 Myb/SANT DNA binding domain containing 5 3.46864
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 3.46864
MYEOV myeloma overexpressed 3.46864
IMPG1 interphotoreceptor matrix proteoglycan 1 3.46864
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 3.46864
IRF8 interferon regulatory factor 8 3.46864
PCDHB13 protocadherin beta 13 3.46864
ZNF436 zinc finger protein 436 3.46864
CPNE6 copine VI (neuronal) 3.46864
ZNF98 zinc finger protein 98 3.46864
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 3.46864
SYCP2 synaptonemal complex protein 2 3.46864
ACR acrosin 3.46864
TSSK4 testis-specific serine kinase 4 3.46864
CBLN3 cerebellin 3 precursor 3.46864
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.46864
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.46864
BEST3 bestrophin 3 3.46864
OPN5 opsin 5 3.46864
BARX2 BARX homeobox 2 3.46864
ARMS2 age-related maculopathy susceptibility 2 3.46864
SPDYC speedy/RINGO cell cycle regulator family member C 3.46864
TBX3 T-box 3 3.46864
MYH13 myosin, heavy chain 13, skeletal muscle 3.46864
SCRT1 scratch family zinc finger 1 3.46864
TSHB thyroid stimulating hormone, beta 3.46864
CLRN1 clarin 1 3.46864
PLA1A phospholipase A1 member A 3.46864
NUTM2F NUT family member 2F 3.46864
LST1 leukocyte specific transcript 1 3.46864
KLK7 kallikrein-related peptidase 7 3.46864
CPSF4L cleavage and polyadenylation specific factor 4-like 3.46864
HK3 hexokinase 3 (white cell) 3.46864
HHIPL2 HHIP-like 2 3.46864
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.46864
LRRC74A leucine rich repeat containing 74A 3.46864
TF transferrin 3.46864
APOL1 apolipoprotein L, 1 3.46864
IL10RA interleukin 10 receptor, alpha 3.46864
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 3.46864
ANKRD53 ankyrin repeat domain 53 3.46864
CDH17 cadherin 17, LI cadherin (liver-intestine) 3.46864
WDFY4 WDFY family member 4 3.46864
ACSM5 acyl-CoA synthetase medium-chain family member 5 3.46864
CSTA cystatin A (stefin A) 3.46864
CLDN34 claudin 34 3.46864
SPATA3 spermatogenesis associated 3 3.46864
CNTF ciliary neurotrophic factor 3.46864
MR1 major histocompatibility complex, class I-related 3.46864
RFPL1 ret finger protein-like 1 3.46864
NIM1K NIM1 serine/threonine protein kinase 3.46864
CABP7 calcium binding protein 7 3.46864
RGCC regulator of cell cycle 3.46864
ZCCHC10 zinc finger, CCHC domain containing 10 3.46864
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 3.46864
ERMN ermin, ERM-like protein 3.46864
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 3.46864
PDCD1 programmed cell death 1 3.46864
RUFY4 RUN and FYVE domain containing 4 3.46864
TEX36 testis expressed 36 3.46864
TGM3 transglutaminase 3 3.46864
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) 3.46864
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 3.46864
CPN2 carboxypeptidase N, polypeptide 2 3.46864
OR10G3 olfactory receptor, family 10, subfamily G, member 3 3.46864
CD22 CD22 molecule 3.46864
ADAM18 ADAM metallopeptidase domain 18 3.46864
IRX1 iroquois homeobox 1 3.46864
CXORF58 chromosome X open reading frame 58 3.46864
MAST1 microtubule associated serine/threonine kinase 1 3.46864
VMO1 vitelline membrane outer layer 1 homolog (chicken) 3.46864
LVRN laeverin 3.46864
TMC3 transmembrane channel-like 3 3.46864
LY6G6C lymphocyte antigen 6 complex, locus G6C 3.46864
LGALS2 lectin, galactoside-binding, soluble, 2 3.46864
CCR10 chemokine (C-C motif) receptor 10 3.46864
PASD1 PAS domain containing 1 3.46864
PRH2 proline-rich protein HaeIII subfamily 2 3.46864
PRSS37 protease, serine, 37 3.46864
AHSG alpha-2-HS-glycoprotein 3.46864
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 3.46864
SH2D1A SH2 domain containing 1A 3.46864
ZNF648 zinc finger protein 648 3.46864
VWC2L von Willebrand factor C domain containing protein 2-like 3.46864
KCTD4 potassium channel tetramerization domain containing 4 3.46864
ICAM2 intercellular adhesion molecule 2 3.46864
ASCL3 achaete-scute family bHLH transcription factor 3 3.46864
C6ORF118 chromosome 6 open reading frame 118 3.43332
OIT3 oncoprotein induced transcript 3 3.43332
GFPT1 glutamine--fructose-6-phosphate transaminase 1 3.16126
POU3F4 POU class 3 homeobox 4 3.06109
SPIN4 spindlin family, member 4 3.02466
TMEM219 transmembrane protein 219 3.01834
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 3.01834
A1CF APOBEC1 complementation factor 3.01834
DLK1 delta-like 1 homolog (Drosophila) 2.91493
TSFM Ts translation elongation factor, mitochondrial 2.87858
FBXO25 F-box protein 25 2.8316
SCT secretin 2.78673
NPR2 natriuretic peptide receptor 2 2.78673
AP3B1 adaptor-related protein complex 3, beta 1 subunit 2.74405
PDLIM7 PDZ and LIM domain 7 (enigma) 2.72095
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.70019
EDC3 enhancer of mRNA decapping 3 2.64849
TPRN taperin 2.61518
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.61407
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 2.61338
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.55396
TAS2R30 taste receptor, type 2, member 30 2.55396
CEP128 centrosomal protein 128kDa 2.55222
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.54988
MARCHF2 membrane associated ring-CH-type finger 2 2.52379
NUP50 nucleoporin 50kDa 2.52379
SGSH N-sulfoglucosamine sulfohydrolase 2.5201
RAB3D RAB3D, member RAS oncogene family 2.51422
SLC35E3 solute carrier family 35, member E3 2.47385
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 2.46762
ZNF146 zinc finger protein 146 2.44881
DGKI diacylglycerol kinase, iota 2.44803
AP3D1 adaptor-related protein complex 3, delta 1 subunit 2.4294
DCLK1 doublecortin-like kinase 1 2.42382
THRSP thyroid hormone responsive 2.42292
VIT vitrin 2.41942
CARM1 coactivator-associated arginine methyltransferase 1 2.40819
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough 2.37722
CAPS2 calcyphosine 2 2.35929
BTN3A2 butyrophilin, subfamily 3, member A2 2.31706
SPMIP2 sperm microtubule inner protein 2 2.28913
ADGRL2 adhesion G protein-coupled receptor L2 2.28651
BZW2 basic leucine zipper and W2 domains 2 2.26641
NQO1 NAD(P)H dehydrogenase, quinone 1 2.26641
DNAL1 dynein, axonemal, light chain 1 2.26641
FBLIM1 filamin binding LIM protein 1 2.25054
USP49 ubiquitin specific peptidase 49 2.24722
NTM neurotrimin 2.23169
WNK3 WNK lysine deficient protein kinase 3 2.22386
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.21213
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 2.16997
R3HDM4 R3H domain containing 4 2.13539
RARG retinoic acid receptor, gamma 2.13226
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.12577
NUP205 nucleoporin 205kDa 2.06729
RAD51D RAD51 paralog D 2.06486
LRRC27 leucine rich repeat containing 27 2.06076
ENTREP1 endosomal transmembrane epsin interactor 1 2.05329
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.04343
RAI1 retinoic acid induced 1 2.04011
HRC histidine rich calcium binding protein 2.03986
RHOQ ras homolog family member Q 2.03967
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.03013
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 2.028
RYR3 ryanodine receptor 3 2.01339
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 2.01339
TSPAN2 tetraspanin 2 2.008
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 2.00676
WDR41 WD repeat domain 41 2.00676
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 2.00605

decreased expression

Symbol Name Standardized Value
ITLN2 intelectin 2 -3.53983
UROS uroporphyrinogen III synthase -3.46864
XKRX XK, Kell blood group complex subunit-related, X-linked -3.46864
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 -3.46864
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 -3.46864
TP53INP2 tumor protein p53 inducible nuclear protein 2 -3.46864
NALCN sodium leak channel, non selective -3.37998
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -3.23985
ODAD1 outer dynein arm docking complex subunit 1 -3.21095
FADS6 fatty acid desaturase 6 -3.21095
CASS4 Cas scaffolding protein family member 4 -3.21095
OSGIN1 oxidative stress induced growth inhibitor 1 -3.21095
OR10A2 olfactory receptor, family 10, subfamily A, member 2 -3.21095
GPRC5A G protein-coupled receptor, class C, group 5, member A -3.21095
C18ORF63 chromosome 18 open reading frame 63 -3.21095
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 -3.21095
HRG histidine-rich glycoprotein -3.21095
FGF9 fibroblast growth factor 9 -3.21095
TLDC2 TBC/LysM-associated domain containing 2 -3.21095
PODNL1 podocan-like 1 -3.21095
PTH2 parathyroid hormone 2 -3.21095
PANO1 proapoptotic nucleolar protein 1 -3.21095
LONRF2 LON peptidase N-terminal domain and ring finger 2 -3.21095
AANAT aralkylamine N-acetyltransferase -3.21095
KRTAP5-11 keratin associated protein 5-11 -3.21095
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B -3.21095
DRD4 dopamine receptor D4 -3.21095
DRD2 dopamine receptor D2 -3.21095
SLA Src-like-adaptor -3.21095
KLF4 Kruppel-like factor 4 (gut) -3.21095
GPR149 G protein-coupled receptor 149 -3.21095
LHX5 LIM homeobox 5 -3.21095
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 -3.21095
C11ORF91 chromosome 11 open reading frame 91 -3.21095
TMEM127 transmembrane protein 127 -3.14623
GCN1 GCN1 activator of EIF2AK4 -3.1196
MBLAC1 metallo-beta-lactamase domain containing 1 -3.07794
HYPK huntingtin interacting protein K -3.07794
NPIPA5 nuclear pore complex interacting protein family, member A5 -3.05388
LINGO1 leucine rich repeat and Ig domain containing 1 -2.90124
COMMD3 COMM domain containing 3 -2.86024
SIK1 salt-inducible kinase 1 -2.80741
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 -2.77622
DGCR6L DiGeorge syndrome critical region gene 6-like -2.70263
IGHMBP2 immunoglobulin mu binding protein 2 -2.7018
PEX10 peroxisomal biogenesis factor 10 -2.66689
EGLN3 egl-9 family hypoxia-inducible factor 3 -2.65516
CRACR2B calcium release activated channel regulator 2B -2.6435
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -2.63081
FAM8A1 family with sequence similarity 8, member A1 -2.60227
NOP14 NOP14 nucleolar protein -2.53295
MORN3 MORN repeat containing 3 -2.52485
WLS wntless Wnt ligand secretion mediator -2.52485
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -2.46824
SCO1 SCO1 cytochrome c oxidase assembly protein -2.42812
MISFA mitochondrial sheath formation associated -2.41625
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -2.38871
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 -2.37635
COMTD1 catechol-O-methyltransferase domain containing 1 -2.32746
CCND1 cyclin D1 -2.30792
MEX3A mex-3 RNA binding family member A -2.3066
DYNLL1 dynein, light chain, LC8-type 1 -2.29697
UBAC2 UBA domain containing 2 -2.27934
H4C11 H4 clustered histone 11 -2.26641
SV2B synaptic vesicle glycoprotein 2B -2.26641
ADI1 acireductone dioxygenase 1 -2.26641
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -2.2552
MSR1 macrophage scavenger receptor 1 -2.23589
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -2.19877
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -2.17129
ERLIN1 ER lipid raft associated 1 -2.1624
HMGXB3 HMG box domain containing 3 -2.14485
SELENBP1 selenium binding protein 1 -2.08583
PPOX protoporphyrinogen oxidase -2.06729
FLRT3 fibronectin leucine rich transmembrane protein 3 -2.06729
CFAP144 cilia and flagella associated protein 144 -2.06729
IQUB IQ motif and ubiquitin domain containing -2.06729
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -2.06729
PNCK pregnancy up-regulated nonubiquitous CaM kinase -2.06729
ACMSD aminocarboxymuconate semialdehyde decarboxylase -2.06486
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase -2.06076
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) -2.06039
MALT1 MALT1 paracaspase -2.05329
MAU2 MAU2 sister chromatid cohesion factor -2.04011
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 -2.04002
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus) -2.0205
ACTA2 actin, alpha 2, smooth muscle, aorta -2.0186
C2ORF80 chromosome 2 open reading frame 80 -2.0186
C1QTNF12 C1q and TNF related 12 -2.0186
CAVIN1 caveolae associated protein 1 -2.0186
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -2.0186
DENND2D DENN/MADD domain containing 2D -2.0186
ADGRG1 adhesion G protein-coupled receptor G1 -2.0186
FAM222A family with sequence similarity 222, member A -2.00676