| Dataset | JASPAR Predicted Transcription Factor Targets |
| Category | genomics |
| Type | transcription factor |
| Description | SRY (sex determining region Y)-box 2|This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6657) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/6657 |
| Similar Terms | |
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5 target genes of the SOX2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
