| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | SRY (sex determining region Y)-box 4|This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6659) |
| External Link | https://ncbi.nlm.nih.gov/gene/6659 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the SOX4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHEK2 | checkpoint kinase 2 | 0.0108339 |
| CA2 | carbonic anhydrase II | 0.0082317 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0081667 |
| GPX2 | glutathione peroxidase 2 | 0.00799498 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00797617 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00793029 |
| ABLIM1 | actin binding LIM protein 1 | 0.00776413 |
| TFF1 | trefoil factor 1 | 0.00766043 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00748325 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00744806 |
| RNASET2 | ribonuclease T2 | 0.00740163 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00738066 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00732897 |
| MX1 | MX dynamin-like GTPase 1 | 0.00723528 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00720828 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00720051 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00714933 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00714018 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00697121 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00697099 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00691269 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00679657 |
| TPD52 | tumor protein D52 | 0.00659487 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0065835 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0065534 |
| MT1M | metallothionein 1M | 0.00655308 |
| SP110 | SP110 nuclear body protein | 0.00641098 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00632143 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00629882 |
| CH25H | cholesterol 25-hydroxylase | 0.00629105 |
| GAS6 | growth arrest-specific 6 | 0.00623925 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00622037 |
| MT1X | metallothionein 1X | 0.0061985 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0061271 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00610734 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.0060133 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00599734 |
| ADCY9 | adenylate cyclase 9 | 0.00595474 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00589914 |
| HOMER1 | homer scaffolding protein 1 | 0.00587922 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00587218 |
| MAP7 | microtubule-associated protein 7 | 0.00586827 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00585542 |
| GATA6 | GATA binding protein 6 | 0.00583624 |
| NRCAM | neuronal cell adhesion molecule | 0.0056891 |
| MX2 | MX dynamin-like GTPase 2 | 0.005677 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00566685 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00566235 |
| FBLN5 | fibulin 5 | 0.00559891 |
| MGLL | monoglyceride lipase | 0.00559133 |
| KRT20 | keratin 20, type I | 0.0055824 |
| RAB21 | RAB21, member RAS oncogene family | 0.0055776 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00557124 |
| FCGBP | Fc fragment of IgG binding protein | 0.00556319 |
| GUCY2C | guanylate cyclase 2C | 0.00554543 |
| RBM34 | RNA binding motif protein 34 | 0.00554124 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00553726 |
| CAPN3 | calpain 3, (p94) | 0.00553651 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00552606 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00552413 |
| LAMB1 | laminin, beta 1 | 0.00550413 |
| FA2H | fatty acid 2-hydroxylase | 0.00548416 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00547926 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00545285 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00542282 |
| TSPAN1 | tetraspanin 1 | 0.00539422 |
| MYRF | myelin regulatory factor | 0.00539126 |
| GOLGA8H | golgin A8 family, member H | 0.00537456 |
| TRIM14 | tripartite motif containing 14 | 0.00537001 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00536676 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0053346 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00529353 |
| LAMA2 | laminin, alpha 2 | 0.00526927 |
| LIF | leukemia inhibitory factor | 0.00526401 |
| CFD | complement factor D (adipsin) | 0.00525031 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00523384 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00523353 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00519766 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00519729 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00516375 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.0051161 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00511044 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.0050948 |
| MALL | mal, T-cell differentiation protein-like | 0.00505186 |
| FBN1 | fibrillin 1 | 0.00505123 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00503876 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00503844 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00500839 |
| C3 | complement component 3 | 0.00497781 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.00495545 |
| MT1F | metallothionein 1F | 0.00494029 |
| MUC13 | mucin 13, cell surface associated | 0.0049261 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0049177 |
| CLIC5 | chloride intracellular channel 5 | 0.00491492 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00490288 |
| MT1G | metallothionein 1G | 0.00488931 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0048832 |
| LAMA3 | laminin, alpha 3 | 0.00484419 |
| PPIF | peptidylprolyl isomerase F | 0.00482174 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00481942 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00481728 |
| IL1R1 | interleukin 1 receptor, type I | 0.00481611 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00477791 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00475541 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.004743 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00473981 |
| MT1E | metallothionein 1E | 0.00473595 |
| IL6 | interleukin 6 | 0.004731 |
| PTHLH | parathyroid hormone-like hormone | 0.00472379 |
| EDN3 | endothelin 3 | 0.00471109 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00468794 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00468778 |
| EPCAM | epithelial cell adhesion molecule | 0.00468463 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00468259 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.00467052 |
| OPTN | optineurin | 0.00466836 |
| PTK6 | protein tyrosine kinase 6 | 0.00465311 |
| TPCN1 | two pore segment channel 1 | 0.00463143 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00461907 |
| IL1R2 | interleukin 1 receptor, type II | 0.0046172 |
| RETREG1 | reticulophagy regulator 1 | 0.00461448 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00460951 |
| TRIM22 | tripartite motif containing 22 | 0.00458611 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00458364 |
| CFH | complement factor H | 0.00457955 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00456689 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00456626 |
| QDPR | quinoid dihydropteridine reductase | 0.00455573 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00455013 |
| MCL1 | myeloid cell leukemia 1 | 0.00452199 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00452127 |
| MT1H | metallothionein 1H | 0.00451857 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00451515 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00450953 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.00449241 |
| NDRG1 | N-myc downstream regulated 1 | 0.00448682 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.00447518 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00446223 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00446049 |
| XAF1 | XIAP associated factor 1 | 0.00444228 |
| KLK10 | kallikrein-related peptidase 10 | 0.00443976 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00443185 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.00442585 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00442418 |
| GCH1 | GTP cyclohydrolase 1 | 0.00442202 |
| PON3 | paraoxonase 3 | 0.00441637 |
| MOCOS | molybdenum cofactor sulfurase | 0.0044111 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00439517 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00439292 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.00436823 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00436325 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00435842 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00434889 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00434854 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0043468 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00434678 |
| RUNX3 | runt-related transcription factor 3 | 0.00433471 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00433177 |
| CTSS | cathepsin S | 0.00431547 |
| DUSP5 | dual specificity phosphatase 5 | 0.00430522 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00429787 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.00429386 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00428503 |
| MLXIP | MLX interacting protein | 0.00426698 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00425334 |
| IFI44L | interferon-induced protein 44-like | 0.00425227 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.004222 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00418747 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00418185 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00417389 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00417326 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00416909 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00413843 |
| IL32 | interleukin 32 | 0.00413763 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.00413106 |
| RAB8A | RAB8A, member RAS oncogene family | 0.00413049 |
| PLAU | plasminogen activator, urokinase | 0.00412847 |
| STC1 | stanniocalcin 1 | 0.00411479 |
| NOP56 | NOP56 ribonucleoprotein | 0.00411111 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00411056 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00410418 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00410196 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00409762 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | 0.00409573 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00409425 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00409265 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00407932 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00407451 |
| TRIM38 | tripartite motif containing 38 | 0.00407319 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00407054 |
| HAL | histidine ammonia-lyase | 0.00406265 |
| TPP1 | tripeptidyl peptidase I | 0.00406117 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00405215 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.0040518 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00404831 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00404669 |
| BST2 | bone marrow stromal cell antigen 2 | 0.0040428 |
| UBAP2 | ubiquitin associated protein 2 | 0.00403945 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00403578 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.004033 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.0040165 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.00401282 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00400953 |
| GPI | glucose-6-phosphate isomerase | 0.0039864 |
| PCNA | proliferating cell nuclear antigen | 0.00397472 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.00397456 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.00397201 |
| PCDH9 | protocadherin 9 | 0.00396708 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 0.00396505 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.00396089 |
| STX3 | syntaxin 3 | 0.00396051 |
| ECM1 | extracellular matrix protein 1 | 0.00395848 |
| HEATR1 | HEAT repeat containing 1 | 0.00395654 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00395623 |
| PYCARD | PYD and CARD domain containing | 0.00395199 |
| PDZD2 | PDZ domain containing 2 | 0.00394936 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0039479 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00393856 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.00393336 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 0.00392942 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00392873 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.0039201 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00391532 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00391164 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00390142 |
| PHB | prohibitin | 0.00390102 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00389937 |
| GSDMB | gasdermin B | 0.00389525 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00389391 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00388483 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00388361 |
| COQ8A | coenzyme Q8A | 0.0038792 |
| KIAA0930 | KIAA0930 | 0.00387898 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00387433 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00387084 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00387077 |
| IL6ST | interleukin 6 signal transducer | 0.00387076 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00386932 |
| HMBOX1 | homeobox containing 1 | 0.00386123 |
| INSR | insulin receptor | 0.00385853 |
| IRF7 | interferon regulatory factor 7 | 0.00385622 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00385522 |
| DST | dystonin | 0.00385125 |
| RBPMS | RNA binding protein with multiple splicing | 0.00383892 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00382733 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00382057 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00382031 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00381938 |
| TSPAN8 | tetraspanin 8 | 0.0038166 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 0.00380563 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB15A | thymosin beta 15a | -0.0130496 |
| BEX1 | brain expressed, X-linked 1 | -0.0100499 |
| S100A8 | S100 calcium binding protein A8 | -0.00949261 |
| PCP4 | Purkinje cell protein 4 | -0.00902307 |
| CLU | clusterin | -0.00821495 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00818932 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00790421 |
| MMP9 | matrix metallopeptidase 9 | -0.00786022 |
| KRT15 | keratin 15, type I | -0.00741656 |
| MEIS1 | Meis homeobox 1 | -0.00735619 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00716202 |
| CRIP2 | cysteine-rich protein 2 | -0.00715231 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00674292 |
| S100A9 | S100 calcium binding protein A9 | -0.00660326 |
| TUBA1A | tubulin, alpha 1a | -0.00656154 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00654416 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.0064515 |
| PFN2 | profilin 2 | -0.00621039 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00584792 |
| ORM1 | orosomucoid 1 | -0.00583867 |
| CDK19 | cyclin-dependent kinase 19 | -0.00570514 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00566167 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00562112 |
| CCNB2 | cyclin B2 | -0.00557773 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.0055682 |
| RTN1 | reticulon 1 | -0.00556454 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00553823 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00547004 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00539715 |
| EREG | epiregulin | -0.00537168 |
| KRT5 | keratin 5, type II | -0.00536326 |
| PDGFC | platelet derived growth factor C | -0.00522072 |
| OBSL1 | obscurin-like 1 | -0.00521576 |
| DCK | deoxycytidine kinase | -0.0051906 |
| ABHD6 | abhydrolase domain containing 6 | -0.00518768 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | -0.00518596 |
| TSPAN6 | tetraspanin 6 | -0.00518189 |
| CD8A | CD8a molecule | -0.0051673 |
| APOA2 | apolipoprotein A-II | -0.00503673 |
| ZBED8 | zinc finger, BED-type containing 8 | -0.00503226 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0050183 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00500138 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00496908 |
| HIST3H2A | histone cluster 3, H2a | -0.00492981 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00492961 |
| CD200 | CD200 molecule | -0.00492865 |
| TSPAN5 | tetraspanin 5 | -0.0049256 |
| KIF20A | kinesin family member 20A | -0.00491976 |
| CHIT1 | chitinase 1 (chitotriosidase) | -0.00490634 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00486409 |
| BEX4 | brain expressed, X-linked 4 | -0.00483756 |
| KIAA0232 | KIAA0232 | -0.00483394 |
| RAPSN | receptor-associated protein of the synapse | -0.00481878 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00477661 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.00473531 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00469256 |
| TSPYL4 | TSPY-like 4 | -0.00467753 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00467636 |
| ATXN1 | ataxin 1 | -0.00465443 |
| TAGLN3 | transgelin 3 | -0.00461309 |
| MMP1 | matrix metallopeptidase 1 | -0.00460285 |
| FADS1 | fatty acid desaturase 1 | -0.00458119 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | -0.00452087 |
| SIRT3 | sirtuin 3 | -0.00451738 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00451431 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00450517 |
| TNC | tenascin C | -0.00450309 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.00448659 |
| KRT13 | keratin 13, type I | -0.00446525 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.0044649 |
| MAL | mal, T-cell differentiation protein | -0.00445072 |
| SELL | selectin L | -0.0044471 |
| NREP | neuronal regeneration related protein | -0.00444528 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00443901 |
| CCNA2 | cyclin A2 | -0.00442496 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00438267 |
| RAP2C | RAP2C, member of RAS oncogene family | -0.00437802 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00436883 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00435472 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00435296 |
| LMNB1 | lamin B1 | -0.00433641 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00433434 |
| RHOB | ras homolog family member B | -0.00432783 |
| HMGB2 | high mobility group box 2 | -0.00431456 |
| PCGF3 | polycomb group ring finger 3 | -0.00430684 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00429393 |
| NUP54 | nucleoporin 54kDa | -0.00425617 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00424882 |
| FBXO3 | F-box protein 3 | -0.00424005 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00422885 |
| LTF | lactotransferrin | -0.00421498 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00420328 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00419456 |
| DENND2D | DENN/MADD domain containing 2D | -0.00418375 |
| COPS4 | COP9 signalosome subunit 4 | -0.00418233 |
| BCL2A1 | BCL2-related protein A1 | -0.00417065 |
| CD2 | CD2 molecule | -0.00416253 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 | -0.00416049 |
| SELENBP1 | selenium binding protein 1 | -0.00414331 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00414295 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00414177 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.00414118 |
| PANK3 | pantothenate kinase 3 | -0.00412798 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00412735 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | -0.00412287 |
| RSBN1 | round spermatid basic protein 1 | -0.00408605 |
| CD99 | CD99 molecule | -0.00407097 |
| MAT2B | methionine adenosyltransferase II, beta | -0.00405976 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00405313 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00404636 |
| CD52 | CD52 molecule | -0.00404634 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | -0.00404135 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00403993 |
| SYT11 | synaptotagmin XI | -0.00402062 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00402024 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00401505 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00401317 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00399891 |
| NES | nestin | -0.00399363 |
| DUSP2 | dual specificity phosphatase 2 | -0.00398402 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00396604 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00396556 |
| STAG2 | stromal antigen 2 | -0.00396306 |
| CCNG2 | cyclin G2 | -0.00395874 |
| FASN | fatty acid synthase | -0.00395305 |
| LDB2 | LIM domain binding 2 | -0.00394957 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00394805 |
| FZD2 | frizzled class receptor 2 | -0.0039468 |
| H1-10 | H1.10 linker histone | -0.00394431 |
| RAB33A | RAB33A, member RAS oncogene family | -0.00394391 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | -0.00393265 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -0.00393048 |
| MB | myoglobin | -0.00391377 |
| SALL2 | spalt-like transcription factor 2 | -0.00390699 |
| HMGB3 | high mobility group box 3 | -0.00388842 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | -0.0038619 |
| SLC35E2B | solute carrier family 35, member E2B | -0.00385779 |
| TMEM35 | transmembrane protein 35 | -0.00385111 |
| CHKB | choline kinase beta | -0.00383743 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00383351 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00382838 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00382748 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00382692 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00382183 |
| NOTCH1 | notch 1 | -0.00381913 |
| ISCA1 | iron-sulfur cluster assembly 1 | -0.00381284 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00380543 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00379645 |
| S100A4 | S100 calcium binding protein A4 | -0.00378805 |
| TMEM187 | transmembrane protein 187 | -0.00377528 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -0.00377334 |
| PTMS | parathymosin | -0.00377295 |
| CD69 | CD69 molecule | -0.0037719 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00376511 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.0037613 |
| TBXA2R | thromboxane A2 receptor | -0.00375928 |
| TPM4 | tropomyosin 4 | -0.00375906 |
| NFE2 | nuclear factor, erythroid 2 | -0.00375725 |
| PSPH | phosphoserine phosphatase | -0.00375273 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00374306 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.0037416 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00373892 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00373193 |
| WLS | wntless Wnt ligand secretion mediator | -0.00372808 |
| ZNF274 | zinc finger protein 274 | -0.00372645 |
| PTN | pleiotrophin | -0.00371975 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.00371001 |
| NEUROD1 | neuronal differentiation 1 | -0.00370994 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.00369153 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00366515 |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 | -0.00366311 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00365422 |
| RNF11 | ring finger protein 11 | -0.0036497 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00363855 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00363679 |
| SETMAR | SET domain and mariner transposase fusion gene | -0.00363541 |
| LRRC17 | leucine rich repeat containing 17 | -0.00362523 |
| NDP | Norrie disease (pseudoglioma) | -0.00362402 |
| INSM1 | insulinoma-associated 1 | -0.00362349 |
| S100A7 | S100 calcium binding protein A7 | -0.00362272 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0036146 |
| NPY | neuropeptide Y | -0.0036053 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -0.00360441 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00360197 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00360082 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.00359223 |
| EXTL2 | exostosin-like glycosyltransferase 2 | -0.00359081 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00358344 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00357542 |
| ZNF226 | zinc finger protein 226 | -0.00356889 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00356196 |
| TMEM14B | transmembrane protein 14B | -0.00354961 |
| STMN1 | stathmin 1 | -0.0035478 |
| VBP1 | von Hippel-Lindau binding protein 1 | -0.00354669 |
| DEK | DEK proto-oncogene | -0.00354302 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.00353371 |
| POSTN | periostin, osteoblast specific factor | -0.00352796 |
| SCP2 | sterol carrier protein 2 | -0.00352527 |
| MDFIC | MyoD family inhibitor domain containing | -0.00352021 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | -0.0035192 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00351879 |
| PIMREG | PICALM interacting mitotic regulator | -0.00351756 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.00351634 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.00351402 |
| ODC1 | ornithine decarboxylase 1 | -0.00351013 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00350728 |
| EFNB3 | ephrin-B3 | -0.00350722 |
| SH3GL3 | SH3-domain GRB2-like 3 | -0.0035056 |
| NCKAP1 | NCK-associated protein 1 | -0.00350348 |
| GPER1 | G protein-coupled estrogen receptor 1 | -0.00349641 |
| CRMP1 | collapsin response mediator protein 1 | -0.0034938 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00348297 |
| RGS1 | regulator of G-protein signaling 1 | -0.00347454 |
| DBN1 | drebrin 1 | -0.00347022 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00346176 |
| FOLR1 | folate receptor 1 (adult) | -0.0034588 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00345195 |
| APOB | apolipoprotein B | -0.00345099 |
| DIRAS2 | DIRAS family, GTP-binding RAS-like 2 | -0.00344909 |
| MAB21L1 | mab-21-like 1 (C. elegans) | -0.00344031 |
| MOSPD1 | motile sperm domain containing 1 | -0.00343911 |
| ANXA5 | annexin A5 | -0.00343802 |
| ADK | adenosine kinase | -0.0034379 |
| OLFM1 | olfactomedin 1 | -0.00343233 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.00343103 |
| RGS4 | regulator of G-protein signaling 4 | -0.00340099 |
| MAGEH1 | melanoma antigen family H1 | -0.00339101 |
| CBX5 | chromobox homolog 5 | -0.00338824 |
| C5AR1 | complement component 5a receptor 1 | -0.00338419 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00338171 |
| EIF1B | eukaryotic translation initiation factor 1B | -0.0033802 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00337641 |
| ZFAND5 | zinc finger, AN1-type domain 5 | -0.0033759 |
| RMI1 | RecQ mediated genome instability 1 | -0.00337529 |
| TMEM165 | transmembrane protein 165 | -0.00337328 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00336971 |
| RPA3 | replication protein A3, 14kDa | -0.0033679 |
| KIF4A | kinesin family member 4A | -0.00336153 |
| CP | ceruloplasmin (ferroxidase) | -0.00336058 |
| GPR183 | G protein-coupled receptor 183 | -0.00335311 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00334758 |
| IL2RB | interleukin 2 receptor, beta | -0.00334614 |
| CRY1 | cryptochrome circadian clock 1 | -0.00334378 |
| EAPP | E2F-associated phosphoprotein | -0.00334157 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | -0.00333428 |
| UNC119B | unc-119 homolog B (C. elegans) | -0.00333397 |
| DEPDC1 | DEP domain containing 1 | -0.00333151 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00333013 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00332766 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.00332717 |
