SP3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description Sp3 transcription factor|This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 6670)
External Link http://www.ncbi.nlm.nih.gov/gene/6670
Similar Terms
Downloads & Tools

Genes

106 interacting proteins for SP3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARID1A AT rich interactive domain 1A (SWI-like)
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
BRCA1 breast cancer 1, early onset
BRD7 bromodomain containing 7
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
C4ORF27 chromosome 4 open reading frame 27
CABIN1 calcineurin binding protein 1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHRAC1 chromatin accessibility complex 1
CKAP5 cytoskeleton associated protein 5
CLOCK clock circadian regulator
CREBBP CREB binding protein
CRX cone-rod homeobox
CTBP1 C-terminal binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1
E2F1 E2F transcription factor 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EP300 E1A binding protein p300
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCH1 GTP cyclohydrolase 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GTF2I general transcription factor IIi
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HLTF helicase-like transcription factor
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGB3 high mobility group box 3
HTT huntingtin
INO80E INO80 complex subunit E
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MBD2 methyl-CpG binding domain protein 2
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MTA3 metastasis associated 1 family, member 3
NAV3 neuron navigator 3
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFIA nuclear factor I/A
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NGEF neuronal guanine nucleotide exchange factor
NKX3-1 NK3 homeobox 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
PARP2 poly (ADP-ribose) polymerase 2
PCNA proliferating cell nuclear antigen
PIAS1 protein inhibitor of activated STAT, 1
PKNOX1 PBX/knotted 1 homeobox 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRDM16 PR domain containing 16
RAD50 RAD50 homolog (S. cerevisiae)
RAN RAN, member RAS oncogene family
RB1 retinoblastoma 1
RBBP4 retinoblastoma binding protein 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100A8 S100 calcium binding protein A8
SAP130 Sin3A-associated protein, 130kDa
SENP1 SUMO1/sentrin specific peptidase 1
SFPQ splicing factor proline/glutamine-rich
SIN3B SIN3 transcription regulator family member B
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SOGA3 SOGA family member 3
SP1 Sp1 transcription factor
STK19 serine/threonine kinase 19
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFCP2 transcription factor CP2
TFCP2L1 transcription factor CP2-like 1
THYN1 thymocyte nuclear protein 1
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TTF2 transcription termination factor, RNA polymerase II
TTK TTK protein kinase
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
UBP1 upstream binding protein 1 (LBP-1a)
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
USF2 upstream transcription factor 2, c-fos interacting
VRK1 vaccinia related kinase 1
WIZ widely interspaced zinc finger motifs
YEATS2 YEATS domain containing 2
YY1 YY1 transcription factor
ZBTB7A zinc finger and BTB domain containing 7A
ZBTB7B zinc finger and BTB domain containing 7B
ZHX3 zinc fingers and homeoboxes 3
ZNF335 zinc finger protein 335
ZNF462 zinc finger protein 462
ZZZ3 zinc finger, ZZ-type containing 3