SPC25 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SPC25, NDC80 kinetochore complex component|This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 57405)
Similar Terms
Downloads & Tools

Genes

232 genes differentially expressed following the SPC25 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
MTMR4 myotubularin related protein 4 2.44969
LURAP1 leucine rich adaptor protein 1 2.44969
C5ORF22 chromosome 5 open reading frame 22 2.41932
CPED1 cadherin-like and PC-esterase domain containing 1 2.41932
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2.41932
RHOJ ras homolog family member J 2.41932
SYT12 synaptotagmin XII 2.41932
KIF6 kinesin family member 6 2.41932
NT5C1A 5'-nucleotidase, cytosolic IA 2.41932
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 2.41932
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.41932
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 2.41932
MYCBP MYC binding protein 2.41932
BICDL2 BICD family like cargo adaptor 2 2.41932
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.41932
TENT5A terminal nucleotidyltransferase 5A 2.41366
PRICKLE1 prickle homolog 1 (Drosophila) 2.41366
ANKRD18B ankyrin repeat domain 18B 2.41366
RCCD1 RCC1 domain containing 1 2.41366
WLS wntless Wnt ligand secretion mediator 2.41366
CIC capicua transcriptional repressor 2.41366
HMGN2 high mobility group nucleosomal binding domain 2 2.41366
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 2.41366
ROGDI rogdi homolog (Drosophila) 2.41366
CELF4 CUGBP, Elav-like family member 4 2.41366
CELF1 CUGBP, Elav-like family member 1 2.41366
MEGF9 multiple EGF-like-domains 9 2.41366
TUBGCP6 tubulin, gamma complex associated protein 6 2.41366
ZNF223 zinc finger protein 223 2.41366
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 2.41366
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.41366
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.41366
ZNF687 zinc finger protein 687 2.41366
PRR11 proline rich 11 2.41366
IL27RA interleukin 27 receptor, alpha 2.41366
LCAT lecithin-cholesterol acyltransferase 2.41366
IRF1 interferon regulatory factor 1 2.41366
SAXO1 stabilizer of axonemal microtubules 1 2.41366
ZCWPW1 zinc finger, CW type with PWWP domain 1 2.41366
CHDH choline dehydrogenase 2.41366
TUBG2 tubulin, gamma 2 2.41366
MKS1 Meckel syndrome, type 1 2.41366
PREB prolactin regulatory element binding 2.41366
PALM paralemmin 2.41366
TTLL10 tubulin tyrosine ligase-like family member 10 2.41366
ATP10A ATPase, class V, type 10A 2.41366
RASEF RAS and EF-hand domain containing 2.41366
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 2.41366
PAOX polyamine oxidase (exo-N4-amino) 2.41366
USHBP1 Usher syndrome 1C binding protein 1 2.41366
TWF1 twinfilin actin binding protein 1 2.41366
FUT2 fucosyltransferase 2 (secretor status included) 2.41366
CREB5 cAMP responsive element binding protein 5 2.41366
KLHL15 kelch-like family member 15 2.41366
MANBAL mannosidase, beta A, lysosomal-like 2.41366
TPGS1 tubulin polyglutamylase complex subunit 1 2.41366
VLDLR very low density lipoprotein receptor 2.41366
RAVER1 ribonucleoprotein, PTB-binding 1 2.41366
TNNT2 troponin T type 2 (cardiac) 2.41366
PRPF4B pre-mRNA processing factor 4B 2.41366
BAG3 BCL2-associated athanogene 3 2.41366
PROSER3 proline and serine rich 3 2.41366
PSD4 pleckstrin and Sec7 domain containing 4 2.41366
TMUB1 transmembrane and ubiquitin-like domain containing 1 2.41366
TMOD3 tropomodulin 3 (ubiquitous) 2.38238
ZSCAN16 zinc finger and SCAN domain containing 16 2.27916
C12ORF57 chromosome 12 open reading frame 57 2.27916
IKZF4 IKAROS family zinc finger 4 (Eos) 2.27916
SPNS1 spinster homolog 1 (Drosophila) 2.27916
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.27916
KCTD9 potassium channel tetramerization domain containing 9 2.27916
ANKEF1 ankyrin repeat and EF-hand domain containing 1 2.27916
BNC2 basonuclin 2 2.2746
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.24679
ALKAL2 ALK and LTK ligand 2 2.24679
DUSP5 dual specificity phosphatase 5 2.24679
GALR1 galanin receptor 1 2.24679
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 2.24679
SETD9 SET domain containing 9 2.24679
LHFPL3 lipoma HMGIC fusion partner-like 3 2.24679
ICAM3 intercellular adhesion molecule 3 2.24679
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 2.24679
COPA coatomer protein complex, subunit alpha 2.19778
ZNF555 zinc finger protein 555 2.13127
MXRA7 matrix-remodelling associated 7 2.13127
LRP10 low density lipoprotein receptor-related protein 10 2.13127
MYLK3 myosin light chain kinase 3 2.13127
TUBE1 tubulin, epsilon 1 2.13127
STPG2 sperm-tail PG-rich repeat containing 2 2.13127
SFT2D3 SFT2 domain containing 3 2.13127
OOEP oocyte expressed protein 2.12308
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 2.11012
TOR2A torsin family 2, member A 2.11012
NSRP1 nuclear speckle splicing regulatory protein 1 2.10686

decreased expression

Symbol Name Standardized Value
PPIF peptidylprolyl isomerase F -2.44969
GOLPH3L golgi phosphoprotein 3-like -2.44969
SRF serum response factor (c-fos serum response element-binding transcription factor) -2.44969
ERRFI1 ERBB receptor feedback inhibitor 1 -2.44969
RHPN2 rhophilin, Rho GTPase binding protein 2 -2.44969
BICD2 bicaudal D homolog 2 (Drosophila) -2.44969
SLC25A46 solute carrier family 25, member 46 -2.44969
LAMB1 laminin, beta 1 -2.44969
BIRC2 baculoviral IAP repeat containing 2 -2.44969
TRIP4 thyroid hormone receptor interactor 4 -2.41932
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) -2.41932
PEDS1 plasmanylethanolamine desaturase 1 -2.41932
C1ORF174 chromosome 1 open reading frame 174 -2.41932
BAD BCL2-associated agonist of cell death -2.41932
ANKRD46 ankyrin repeat domain 46 -2.41932
SWT1 SWT1 RNA endoribonuclease homolog (S. cerevisiae) -2.41366
SERTAD2 SERTA domain containing 2 -2.41366
ELL elongation factor RNA polymerase II -2.41366
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) -2.41366
PXDNL peroxidasin-like -2.41366
RNF6 ring finger protein (C3H2C3 type) 6 -2.41366
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -2.41366
CYTL1 cytokine-like 1 -2.41366
ADO 2-aminoethanethiol (cysteamine) dioxygenase -2.41366
FAM229B family with sequence similarity 229, member B -2.41366
RAB23 RAB23, member RAS oncogene family -2.41366
DMAP1 DNA methyltransferase 1 associated protein 1 -2.41366
IRS1 insulin receptor substrate 1 -2.41366
FABP3 fatty acid binding protein 3, muscle and heart -2.41366
FKTN fukutin -2.41366
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -2.41366
NOA1 nitric oxide associated 1 -2.41366
A1BG alpha-1-B glycoprotein -2.41366
THAP2 THAP domain containing, apoptosis associated protein 2 -2.41366
PRMT8 protein arginine methyltransferase 8 -2.41366
LAMC2 laminin, gamma 2 -2.41366
ING3 inhibitor of growth family, member 3 -2.41366
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 -2.41366
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) -2.41366
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -2.41366
TWNK twinkle mtDNA helicase -2.41366
TEDC2 tubulin epsilon and delta complex 2 -2.41366
RIGI RNA sensor RIG-I -2.41366
CFAP161 cilia and flagella associated protein 161 -2.41366
MIMS2 mitochondrial inner membrane scaffold 2 -2.41366
ODAD3 outer dynein arm docking complex subunit 3 -2.41366
STMP1 short transmembrane mitochondrial protein 1 -2.41366
LOC122455342 testis-specific serine/proline-rich protein -2.41366
CEP15 centrosomal protein 15 -2.41366
EMID1 EMI domain containing 1 -2.41366
HSPA2 heat shock 70kDa protein 2 -2.41366
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -2.41366
TEK TEK tyrosine kinase, endothelial -2.41366
METAP1D methionyl aminopeptidase type 1D (mitochondrial) -2.41366
CDK5 cyclin-dependent kinase 5 -2.41366
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3 -2.41366
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) -2.41366
TFE3 transcription factor binding to IGHM enhancer 3 -2.41366
LZTS1 leucine zipper, putative tumor suppressor 1 -2.41366
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -2.41366
AP3B2 adaptor-related protein complex 3, beta 2 subunit -2.41366
PNPLA8 patatin-like phospholipase domain containing 8 -2.41366
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) -2.41366
LAMA3 laminin, alpha 3 -2.41366
VCF2 VCP nuclear cofactor family member 2 -2.41366
BEX5 brain expressed, X-linked 5 -2.41366
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein -2.41366
HDAC2 histone deacetylase 2 -2.41366
CDT1 chromatin licensing and DNA replication factor 1 -2.41366
DENND4A DENN/MADD domain containing 4A -2.41366
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -2.41366
RASGEF1B RasGEF domain family, member 1B -2.41366
CLK1 CDC-like kinase 1 -2.41366
WDR74 WD repeat domain 74 -2.41366
AK9 adenylate kinase 9 -2.41366
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 -2.41366
REEP2 receptor accessory protein 2 -2.41366
ZNF787 zinc finger protein 787 -2.41366
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -2.41366
UNC50 unc-50 homolog (C. elegans) -2.41366
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -2.41366
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 -2.41366
IGSF9 immunoglobulin superfamily, member 9 -2.41366
CFAP69 cilia and flagella associated protein 69 -2.41366
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -2.41366
PEF1 penta-EF-hand domain containing 1 -2.41366
GALNS galactosamine (N-acetyl)-6-sulfatase -2.41366
CCDC174 coiled-coil domain containing 174 -2.41366
KANSL1L KAT8 regulatory NSL complex subunit 1-like -2.41366
TMED8 transmembrane emp24 protein transport domain containing 8 -2.41366
SOBP sine oculis binding protein homolog (Drosophila) -2.41366
ANGEL1 angel homolog 1 (Drosophila) -2.41366
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -2.41366
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -2.41366
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 -2.41366
ZNF480 zinc finger protein 480 -2.41366
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -2.41366
MAP3K8 mitogen-activated protein kinase kinase kinase 8 -2.41366
EMC1 ER membrane protein complex subunit 1 -2.41366
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) -2.41366
GRN granulin -2.41366
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.41366
DGKG diacylglycerol kinase, gamma 90kDa -2.41366
SDC3 syndecan 3 -2.41366
PRDM11 PR domain containing 11 -2.41366
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -2.41366
AMDHD2 amidohydrolase domain containing 2 -2.41366
FBXO31 F-box protein 31 -2.39303
CPVL carboxypeptidase, vitellogenic-like -2.39303
RAB40C RAB40C, member RAS oncogene family -2.39303
MSI1 musashi RNA-binding protein 1 -2.39303
GUCY2C guanylate cyclase 2C -2.39303
MYOZ3 myozenin 3 -2.39303
VAMP7 vesicle-associated membrane protein 7 -2.39303
ZMYM5 zinc finger, MYM-type 5 -2.32848
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 -2.32848
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -2.24679
MARCKS myristoylated alanine-rich protein kinase C substrate -2.23469
PNPLA4 patatin-like phospholipase domain containing 4 -2.16295
UHMK1 U2AF homology motif (UHM) kinase 1 -2.16295
THOP1 thimet oligopeptidase 1 -2.16295
CMC4 C-x(9)-C motif containing 4 -2.16295
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -2.15235
RAD51 RAD51 recombinase -2.13127
PRMT9 protein arginine methyltransferase 9 -2.12631
LPAR2 lysophosphatidic acid receptor 2 -2.12631
KCTD2 potassium channel tetramerization domain containing 2 -2.12631
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -2.12631
RABL3 RAB, member of RAS oncogene family-like 3 -2.12631
LRP4 low density lipoprotein receptor-related protein 4 -2.12631
RWDD4 RWD domain containing 4 -2.12631
ANKH ANKH inorganic pyrophosphate transport regulator -2.12631
YPEL3 yippee-like 3 (Drosophila) -2.11163
NOP16 NOP16 nucleolar protein -2.11163
CYB5A cytochrome b5 type A (microsomal) -2.10686
JPT2 Jupiter microtubule associated homolog 2 -2.07792
PLD3 phospholipase D family, member 3 -2.07792
RETREG3 reticulophagy regulator family member 3 -2.00637