SPC25 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description SPC25, NDC80 kinetochore complex component|This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 57405)
External Link https://ncbi.nlm.nih.gov/gene/57405
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Genes

500 genes differentially expressed following the SPC25 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL9 chemokine (C-X-C motif) ligand 9 0.0160951
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0143987
COLEC12 collectin sub-family member 12 0.0126139
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0122414
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0120881
SDC2 syndecan 2 0.0117268
SEPP1 selenoprotein P, plasma, 1 0.0109941
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.0109505
LOX lysyl oxidase 0.0103473
ENO2 enolase 2 (gamma, neuronal) 0.0101956
IDO1 indoleamine 2,3-dioxygenase 1 0.0101319
RAPSN receptor-associated protein of the synapse 0.0100797
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.0100147
KIF20A kinesin family member 20A 0.0098575
GBP1 guanylate binding protein 1, interferon-inducible 0.00978099
PRC1 protein regulator of cytokinesis 1 0.00971091
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00969226
MMP12 matrix metallopeptidase 12 0.00944917
EXOSC4 exosome component 4 0.00944369
TMSB15A thymosin beta 15a 0.00932623
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00906086
CXCL10 chemokine (C-X-C motif) ligand 10 0.00874925
SRSF1 serine/arginine-rich splicing factor 1 0.0084672
RXRA retinoid X receptor, alpha 0.00843921
H1-0 H1.0 linker histone 0.00841916
GLUL glutamate-ammonia ligase 0.00840714
HNMT histamine N-methyltransferase 0.00835897
EMP3 epithelial membrane protein 3 0.00826483
NUSAP1 nucleolar and spindle associated protein 1 0.00826185
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00826052
SFTPC surfactant protein C 0.00815821
CENPX centromere protein X 0.00810471
SFTPD surfactant protein D 0.00808719
ADAMDEC1 ADAM-like, decysin 1 0.00807628
TIMP3 TIMP metallopeptidase inhibitor 3 0.00807203
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00805072
EPHB2 EPH receptor B2 0.00804695
SFTPA2 surfactant protein A2 0.00803191
PER3 period circadian clock 3 0.00799946
KDM5D lysine (K)-specific demethylase 5D 0.00798736
GANAB glucosidase, alpha; neutral AB 0.00796654
CCNA2 cyclin A2 0.00793864
DPYD dihydropyrimidine dehydrogenase 0.00791991
CNN3 calponin 3, acidic 0.00788382
CDC20 cell division cycle 20 0.00785413
FAM13A family with sequence similarity 13, member A 0.00783587
OLFM1 olfactomedin 1 0.00782984
MPP1 membrane protein, palmitoylated 1, 55kDa 0.00781197
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0077842
MDFIC MyoD family inhibitor domain containing 0.00776734
SYNGR3 synaptogyrin 3 0.00776505
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00775241
TNC tenascin C 0.00775123
SIRT3 sirtuin 3 0.00773111
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00769727
HMGB1 high mobility group box 1 0.00763709
PLD3 phospholipase D family, member 3 0.00761406
DUT deoxyuridine triphosphatase 0.00761211
HMGB2 high mobility group box 2 0.00756536
CD163 CD163 molecule 0.00753206
TMEM106C transmembrane protein 106C 0.00750205
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00747792
PTMS parathymosin 0.00743766
ANPEP alanyl (membrane) aminopeptidase 0.00741471
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00740137
IDE insulin-degrading enzyme 0.00736515
IGSF6 immunoglobulin superfamily, member 6 0.00734712
C1QA complement component 1, q subcomponent, A chain 0.00732795
MAMLD1 mastermind-like domain containing 1 0.00728279
BAD BCL2-associated agonist of cell death 0.00727521
CIT citron rho-interacting serine/threonine kinase 0.00723295
KIF1B kinesin family member 1B 0.00722717
TYMP thymidine phosphorylase 0.00721287
MCOLN1 mucolipin 1 0.00719478
BIRC5 baculoviral IAP repeat containing 5 0.007164
OIP5 Opa interacting protein 5 0.00712725
CDC45 cell division cycle 45 0.00707868
TNS3 tensin 3 0.00705763
RAD23A RAD23 homolog A (S. cerevisiae) 0.00704377
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00703849
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00703431
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00700153
ALPL alkaline phosphatase, liver/bone/kidney 0.00697469
C4BPA complement component 4 binding protein, alpha 0.00697339
FOXM1 forkhead box M1 0.00692279
APOC1 apolipoprotein C-I 0.00687696
C1QB complement component 1, q subcomponent, B chain 0.00687062
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.00685916
BST2 bone marrow stromal cell antigen 2 0.00685905
COL5A1 collagen, type V, alpha 1 0.00682997
KLHDC3 kelch domain containing 3 0.00680137
DCXR dicarbonyl/L-xylulose reductase 0.00677049
TMEM45A transmembrane protein 45A 0.0067702
GCHFR GTP cyclohydrolase I feedback regulator 0.00674828
GBAP1 glucosidase, beta, acid pseudogene 1 0.00672526
PRDX2 peroxiredoxin 2 0.0066553
FASN fatty acid synthase 0.00661075
FADS1 fatty acid desaturase 1 0.00660903
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00658
SEPTIN10 septin 10 0.0065765
MECOM MDS1 and EVI1 complex locus 0.00655466
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00655142
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.00654231
MCTP1 multiple C2 domains, transmembrane 1 0.00653668
FGFR3 fibroblast growth factor receptor 3 0.00653316
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00653104
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00651995
UBE2S ubiquitin-conjugating enzyme E2S 0.00649225
BASP1 brain abundant, membrane attached signal protein 1 0.00644566
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00644519
ANO10 anoctamin 10 0.00642227
LDOC1 leucine zipper, down-regulated in cancer 1 0.0064159
AURKA aurora kinase A 0.00639687
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.0063913
IFI30 interferon, gamma-inducible protein 30 0.00638397
CLIC2 chloride intracellular channel 2 0.00638348
CLEC7A C-type lectin domain family 7, member A 0.00637406
STMN1 stathmin 1 0.0063719
TMCO3 transmembrane and coiled-coil domains 3 0.006366
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00636068
PRMT1 protein arginine methyltransferase 1 0.00635593
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00635062
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.00634415
GSTA4 glutathione S-transferase alpha 4 0.00633527
METTL7A methyltransferase like 7A 0.00633497
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.00632858
ECI1 enoyl-CoA delta isomerase 1 0.00632679
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.00630165
MCM5 minichromosome maintenance complex component 5 0.00629375
CPM carboxypeptidase M 0.00628655
LST1 leukocyte specific transcript 1 0.00628423
TMEM259 transmembrane protein 259 0.00627141
RHOA ras homolog family member A 0.00624954
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.00623307
PDZD2 PDZ domain containing 2 0.00622647
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.00621888
CXCL13 chemokine (C-X-C motif) ligand 13 0.00620062
NCAPD3 non-SMC condensin II complex, subunit D3 0.00618809
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00618117
TK1 thymidine kinase 1, soluble 0.00617071
MEX3D mex-3 RNA binding family member D 0.00616615
PCLAF PCNA clamp associated factor 0.00615905
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00614871
PPP5C protein phosphatase 5, catalytic subunit 0.00614727
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.00614384
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00612592
CDC25B cell division cycle 25B 0.0061244
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 0.00612302
AMH anti-Mullerian hormone 0.00609259
TMEM14A transmembrane protein 14A 0.00608486
DAPK1 death-associated protein kinase 1 0.00607765
CST3 cystatin C 0.00607763
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.00607357
GOLIM4 golgi integral membrane protein 4 0.00606238
SH3GLB2 SH3-domain GRB2-like endophilin B2 0.00604215
NNT nicotinamide nucleotide transhydrogenase 0.00603569
EPAS1 endothelial PAS domain protein 1 0.00603389
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00603246
AHNAK AHNAK nucleoprotein 0.00602059
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.00601548
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00601265
HP haptoglobin 0.00600875
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00600519
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.0060041
GLOD4 glyoxalase domain containing 4 0.00598296
CTNND1 catenin (cadherin-associated protein), delta 1 0.00598228
TMEM126B transmembrane protein 126B 0.00594406
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00594081
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00593587
PRDX4 peroxiredoxin 4 0.00593115
PBK PDZ binding kinase 0.00591739
CBS cystathionine-beta-synthase 0.00591444
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00591362
FEN1 flap structure-specific endonuclease 1 0.00591339
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.00588887
MRPL12 mitochondrial ribosomal protein L12 0.00588731
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00588306
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00586771
NCKIPSD NCK interacting protein with SH3 domain 0.0058665
TRMT5 tRNA methyltransferase 5 0.00585459
STMN2 stathmin 2 0.00584637
KIF18B kinesin family member 18B 0.00580943
PSRC1 proline/serine-rich coiled-coil 1 0.0058059
AURKB aurora kinase B 0.0058059
CCNL2 cyclin L2 0.00579779
NADK NAD kinase 0.00578798
NRGN neurogranin (protein kinase C substrate, RC3) 0.00576523
RTL8C retrotransposon Gag like 8C 0.00576344
SULF1 sulfatase 1 0.00575976
SSBP2 single-stranded DNA binding protein 2 0.00575692
CENPF centromere protein F, 350/400kDa 0.00573115
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00571898
FPR3 formyl peptide receptor 3 0.00570403
ZWINT ZW10 interacting kinetochore protein 0.00569804
SELENBP1 selenium binding protein 1 0.00566697
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00566159
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 0.00566026
DEPDC1 DEP domain containing 1 0.00565091
NUPR1 nuclear protein, transcriptional regulator, 1 0.00564718
KIF4A kinesin family member 4A 0.0056459
TACC3 transforming, acidic coiled-coil containing protein 3 0.0056267
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00562628
ECI2 enoyl-CoA delta isomerase 2 0.00562256
RAD23B RAD23 homolog B (S. cerevisiae) 0.00561742
CAMK1 calcium/calmodulin-dependent protein kinase I 0.00560608
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00556991
CXCL11 chemokine (C-X-C motif) ligand 11 0.00555946
MCM2 minichromosome maintenance complex component 2 0.00555932
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00555039
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 0.00554613
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0055447
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.00552269
PLEK pleckstrin 0.00551818
NSD2 nuclear receptor binding SET domain protein 2 0.00551484
RNASEH2A ribonuclease H2, subunit A 0.00550733
GAMT guanidinoacetate N-methyltransferase 0.0054982
DRAM1 DNA-damage regulated autophagy modulator 1 0.00549015
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00548041
NINJ2 ninjurin 2 0.00547514
ACTL6A actin-like 6A 0.00545458
CD320 CD320 molecule 0.00544956
THY1 Thy-1 cell surface antigen 0.00544746
MRPS12 mitochondrial ribosomal protein S12 0.00544623
NNMT nicotinamide N-methyltransferase 0.00544214
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.00543276
EHBP1 EH domain binding protein 1 0.00542609
SIAH2 siah E3 ubiquitin protein ligase 2 0.00541814
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.00540119
LMNB1 lamin B1 0.00539099
ASF1B anti-silencing function 1B histone chaperone 0.00538773
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.00537736
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00537403
CDKN3 cyclin-dependent kinase inhibitor 3 0.00536965
ENO1 enolase 1, (alpha) 0.00535854
GET1 guided entry of tail-anchored proteins factor 1 0.00535635
C10ORF10 chromosome 10 open reading frame 10 0.00533157
TPX2 TPX2, microtubule-associated 0.00531882
SMC4 structural maintenance of chromosomes 4 0.00530457
NCOR2 nuclear receptor corepressor 2 0.00529986
HMGB3 high mobility group box 3 0.00529145
CCDC92 coiled-coil domain containing 92 0.00529132
TGM2 transglutaminase 2 0.0052912
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00528925
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00528084
SPTSSA serine palmitoyltransferase, small subunit A 0.00528053
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.00526693
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.00526617
CHN1 chimerin 1 0.00526532
GCK glucokinase (hexokinase 4) 0.00525791
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.00525166

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0265769
PROM1 prominin 1 -0.0217249
LCN2 lipocalin 2 -0.0216516
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0178824
KRT14 keratin 14, type I -0.0162731
SRPX sushi-repeat containing protein, X-linked -0.0155808
PTHLH parathyroid hormone-like hormone -0.01461
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0144034
CRYAB crystallin, alpha B -0.0139134
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.013472
TACSTD2 tumor-associated calcium signal transducer 2 -0.0133777
TFPI2 tissue factor pathway inhibitor 2 -0.0133363
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0131114
S100P S100 calcium binding protein P -0.0130461
CSTA cystatin A (stefin A) -0.0127336
KRT23 keratin 23, type I -0.0127214
DLK1 delta-like 1 homolog (Drosophila) -0.012572
PEG3 paternally expressed 3 -0.012479
HSPA1A heat shock 70kDa protein 1A -0.0119702
SOBP sine oculis binding protein homolog (Drosophila) -0.0119403
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0119071
MXRA7 matrix-remodelling associated 7 -0.0116708
CYTL1 cytokine-like 1 -0.0115929
PIP prolactin-induced protein -0.0114836
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0114355
THBS2 thrombospondin 2 -0.0114156
BHLHE41 basic helix-loop-helix family, member e41 -0.0113388
LTF lactotransferrin -0.0112902
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.0112129
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0112074
SCGB2A2 secretoglobin, family 2A, member 2 -0.0111429
IFI27 interferon, alpha-inducible protein 27 -0.0110291
NIBAN1 niban apoptosis regulator 1 -0.011009
ADD3 adducin 3 (gamma) -0.0110019
SLPI secretory leukocyte peptidase inhibitor -0.0107438
MYH11 myosin, heavy chain 11, smooth muscle -0.0106748
HOMER1 homer scaffolding protein 1 -0.0106643
IER5 immediate early response 5 -0.0106634
MMP7 matrix metallopeptidase 7 -0.0106417
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.0105912
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -0.0104798
ACTG2 actin, gamma 2, smooth muscle, enteric -0.0104347
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0104134
KRT19 keratin 19, type I -0.0103254
MPO myeloperoxidase -0.0103126
RRAGD Ras-related GTP binding D -0.0103022
KRT13 keratin 13, type I -0.0102963
JAG1 jagged 1 -0.0102033
XIC X chromosome inactivation center -0.0101789
SH3YL1 SH3 and SYLF domain containing 1 -0.0101756
HSPB8 heat shock 22kDa protein 8 -0.0101621
AQP3 aquaporin 3 (Gill blood group) -0.0101454
SYNM synemin, intermediate filament protein -0.0101014
CCL20 chemokine (C-C motif) ligand 20 -0.0100993
FABP4 fatty acid binding protein 4, adipocyte -0.010031
INAVA innate immunity activator -0.0100074
ANK2 ankyrin 2, neuronal -0.0100064
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00998997
TGFBR3 transforming growth factor, beta receptor III -0.00998084
C3 complement component 3 -0.00991175
SFRP4 secreted frizzled-related protein 4 -0.0098354
HTRA1 HtrA serine peptidase 1 -0.00980772
CRISP3 cysteine-rich secretory protein 3 -0.00976569
KRT15 keratin 15, type I -0.00969109
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00968663
GPM6B glycoprotein M6B -0.0096829
ANXA1 annexin A1 -0.00964245
JMJD6 jumonji domain containing 6 -0.00961134
LHFP lipoma HMGIC fusion partner -0.00956759
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00950687
ASS1 argininosuccinate synthase 1 -0.00942788
MCAM melanoma cell adhesion molecule -0.00940716
S100A11 S100 calcium binding protein A11 -0.00938844
OGN osteoglycin -0.00936183
APOD apolipoprotein D -0.00919605
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00917997
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.0091395
S100A8 S100 calcium binding protein A8 -0.0091019
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00907819
FBLN5 fibulin 5 -0.00903942
FABP7 fatty acid binding protein 7, brain -0.0090366
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00902345
AREG amphiregulin -0.00901743
COL14A1 collagen, type XIV, alpha 1 -0.0089468
CRABP1 cellular retinoic acid binding protein 1 -0.00880948
OAT ornithine aminotransferase -0.00879904
AKAP12 A kinase (PRKA) anchor protein 12 -0.00878017
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00872868
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00865822
KLK6 kallikrein-related peptidase 6 -0.00861929
SCGB2A1 secretoglobin, family 2A, member 1 -0.00859875
RNF167 ring finger protein 167 -0.00854805
TAC1 tachykinin, precursor 1 -0.00854076
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0085204
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00851414
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00849114
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00842498
IPO13 importin 13 -0.00841009
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00839994
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00838912
ITM2A integral membrane protein 2A -0.00831912
ATF3 activating transcription factor 3 -0.00831852
TRIM29 tripartite motif containing 29 -0.00830812
CFD complement factor D (adipsin) -0.0082889
KRT5 keratin 5, type II -0.00823805
KLK10 kallikrein-related peptidase 10 -0.00823058
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00819044
SVIL supervillin -0.008189
CNN1 calponin 1, basic, smooth muscle -0.00815262
PTK2 protein tyrosine kinase 2 -0.00814462
SPARCL1 SPARC-like 1 (hevin) -0.0081261
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00807064
LDB3 LIM domain binding 3 -0.0080258
RGS5 regulator of G-protein signaling 5 -0.00797661
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00792597
PADI2 peptidyl arginine deiminase, type II -0.00792184
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00787981
BBX bobby sox homolog (Drosophila) -0.00786992
C7 complement component 7 -0.00786405
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00785661
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00779449
ZNF721 zinc finger protein 721 -0.00778005
KLK11 kallikrein-related peptidase 11 -0.00768561
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00767844
SCGB1D2 secretoglobin, family 1D, member 2 -0.00767369
CCN2 cellular communication network factor 2 -0.00766453
HDAC9 histone deacetylase 9 -0.00765604
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00760655
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00752859
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00752225
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00746925
DDIT3 DNA-damage-inducible transcript 3 -0.00746374
LPAR6 lysophosphatidic acid receptor 6 -0.00745308
PDZK1IP1 PDZK1 interacting protein 1 -0.00743784
YPEL5 yippee-like 5 (Drosophila) -0.00742385
LBH limb bud and heart development -0.00742018
CAPN3 calpain 3, (p94) -0.00741856
S100A12 S100 calcium binding protein A12 -0.00740182
S100A9 S100 calcium binding protein A9 -0.0073895
ISG20 interferon stimulated exonuclease gene 20kDa -0.00737817
OLFM4 olfactomedin 4 -0.00736699
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.00731103
MSMB microseminoprotein, beta- -0.00730554
HBEGF heparin-binding EGF-like growth factor -0.00725264
SELE selectin E -0.00722914
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00720888
GOLGA8H golgin A8 family, member H -0.00718864
SMAD3 SMAD family member 3 -0.00714284
WT1 Wilms tumor 1 -0.00713394
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00712709
RTCA RNA 3'-terminal phosphate cyclase -0.00712142
HMOX1 heme oxygenase 1 -0.00708697
SPRR3 small proline-rich protein 3 -0.00707445
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00706689
RAB29 RAB29, member RAS oncogene family -0.00705966
DES desmin -0.00705739
PITX3 paired-like homeodomain 3 -0.00705155
IL1RN interleukin 1 receptor antagonist -0.00703434
NT5C2 5'-nucleotidase, cytosolic II -0.00703097
EGR1 early growth response 1 -0.00700713
IL1A interleukin 1, alpha -0.00699924
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 -0.00698372
MEX3C mex-3 RNA binding family member C -0.0069789
ECM1 extracellular matrix protein 1 -0.00697385
PABPC3 poly(A) binding protein, cytoplasmic 3 -0.00696169
BTG2 BTG family, member 2 -0.00695358
ELF1 E74-like factor 1 (ets domain transcription factor) -0.00694714
AUTS2 autism susceptibility candidate 2 -0.00692318
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00692212
TSPYL5 TSPY-like 5 -0.0069215
DLD dihydrolipoamide dehydrogenase -0.00692091
GALC galactosylceramidase -0.0069207
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.0069117
FAM107A family with sequence similarity 107, member A -0.00690339
FRZB frizzled-related protein -0.00689182
FCGBP Fc fragment of IgG binding protein -0.00688843
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00687799
TRIM38 tripartite motif containing 38 -0.00685007
JUP junction plakoglobin -0.00684096
CXCL6 chemokine (C-X-C motif) ligand 6 -0.00683734
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00683516
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00682364
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00679413
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00678065
MUC16 mucin 16, cell surface associated -0.00677373
MAOB monoamine oxidase B -0.00674865
SFRP1 secreted frizzled-related protein 1 -0.00673629
ZNF160 zinc finger protein 160 -0.00673505
NKG7 natural killer cell granule protein 7 -0.00671411
PARP8 poly (ADP-ribose) polymerase family, member 8 -0.00670591
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.00669244
SLC16A4 solute carrier family 16, member 4 -0.00669156
VNN1 vanin 1 -0.00668904
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -0.00668181
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -0.00667329
ADGRG2 adhesion G protein-coupled receptor G2 -0.00663681
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00663423
LAMC2 laminin, gamma 2 -0.00661705
QPRT quinolinate phosphoribosyltransferase -0.00660573
UPK1B uroplakin 1B -0.00659831
PUF60 poly-U binding splicing factor 60KDa -0.00657598
MYBPC1 myosin binding protein C, slow type -0.00656314
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00653922
CCND3 cyclin D3 -0.00651785
EGR2 early growth response 2 -0.00651645
FGF1 fibroblast growth factor 1 (acidic) -0.0065025
IL6 interleukin 6 -0.00648608
CHD7 chromodomain helicase DNA binding protein 7 -0.00646611
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.0064585
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00644793
MMP8 matrix metallopeptidase 8 -0.00644601
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00644348
FMO1 flavin containing monooxygenase 1 -0.00644173
GEM GTP binding protein overexpressed in skeletal muscle -0.00642654
EPCAM epithelial cell adhesion molecule -0.00641784
RIPK4 receptor-interacting serine-threonine kinase 4 -0.0063666
ERP44 endoplasmic reticulum protein 44 -0.00635795
TRAPPC2 trafficking protein particle complex 2 -0.00634417
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00633947
KLHL24 kelch-like family member 24 -0.00632043
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00628838
BIK BCL2-interacting killer (apoptosis-inducing) -0.00627847
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00626437
SGCE sarcoglycan, epsilon -0.00625714
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00624591
CLEC11A C-type lectin domain family 11, member A -0.00624239
ZNF394 zinc finger protein 394 -0.0062314
PDLIM3 PDZ and LIM domain 3 -0.00622949
ERMP1 endoplasmic reticulum metallopeptidase 1 -0.0062067
CST7 cystatin F (leukocystatin) -0.00620341
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00618982
HIST1H2BD histone cluster 1, H2bd -0.00618608
RRAD Ras-related associated with diabetes -0.00617344
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00616629
DEFA4 defensin, alpha 4, corticostatin -0.00616057
FRMD4B FERM domain containing 4B -0.00616017
SSPN sarcospan -0.00614613
SERINC5 serine incorporator 5 -0.00613442
UPP1 uridine phosphorylase 1 -0.00613414
PNMA8A PNMA family member 8A -0.00612098
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00610915
LARP6 La ribonucleoprotein domain family, member 6 -0.0060956
VPREB1 pre-B lymphocyte 1 -0.00607913
NCALD neurocalcin delta -0.00605525
WFDC1 WAP four-disulfide core domain 1 -0.00605495
PEG10 paternally expressed 10 -0.00604686
C6ORF48 chromosome 6 open reading frame 48 -0.00603881
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00602095
SCPEP1 serine carboxypeptidase 1 -0.00601391
TUBB6 tubulin, beta 6 class V -0.00600204