SPEN Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description spen family transcriptional repressor|This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23013)
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Genes

395 genes differentially expressed following the SPEN gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
EQTN equatorin, sperm acrosome associated 3.09309
GREM1 gremlin 1, DAN family BMP antagonist 3.09309
APOH apolipoprotein H (beta-2-glycoprotein I) 3.09309
LRRC4 leucine rich repeat containing 4 3.09309
FOXG1 forkhead box G1 3.09309
SIM1 single-minded family bHLH transcription factor 1 3.09309
MYH2 myosin, heavy chain 2, skeletal muscle, adult 3.09309
C2ORF72 chromosome 2 open reading frame 72 3.09309
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 3.09309
GATA4 GATA binding protein 4 3.09309
GTF2A1L general transcription factor IIA, 1-like 3.09309
LIX1 Lix1 homolog (chicken) 3.09309
IER5L immediate early response 5-like 3.09309
OR52H1 olfactory receptor, family 52, subfamily H, member 1 3.09309
SCN2B sodium channel, voltage gated, type II beta subunit 3.09309
PTGES prostaglandin E synthase 3.09309
CCR3 chemokine (C-C motif) receptor 3 3.09309
CCNB3 cyclin B3 3.09309
TBX15 T-box 15 3.09309
MAGED4 melanoma antigen family D4 3.09309
DND1 DND microRNA-mediated repression inhibitor 1 3.09309
ATAD3C ATPase family, AAA domain containing 3C 3.09309
BMP1 bone morphogenetic protein 1 3.09309
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 3.09309
LAMB4 laminin, beta 4 3.09309
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.09309
DEFB131B defensin beta 131B 3.09309
SPMAP2L sperm microtubule associated protein 2 like 3.09309
EPOP elongin BC and polycomb repressive complex 2 associated protein 3.09309
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 3.09309
IL4I1 interleukin 4 induced 1 2.96379
SIX2 SIX homeobox 2 2.96379
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.96379
CD96 CD96 molecule 2.96379
PRDM13 PR domain containing 13 2.96379
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.96379
CDH5 cadherin 5, type 2 (vascular endothelium) 2.96379
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.96379
TMC3 transmembrane channel-like 3 2.96379
CD5 CD5 molecule 2.96379
ZACN zinc activated ligand-gated ion channel 2.96379
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 2.96379
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.96379
WDR87 WD repeat domain 87 2.96379
SCNN1G sodium channel, non voltage gated 1 gamma subunit 2.96379
CLEC12A C-type lectin domain family 12, member A 2.96379
SP5 Sp5 transcription factor 2.96379
PDYN prodynorphin 2.96379
PEAR1 platelet endothelial aggregation receptor 1 2.96379
SFTPB surfactant protein B 2.96379
CRYGN crystallin, gamma N 2.96379
BHLHE40 basic helix-loop-helix family, member e40 2.96379
PRODH proline dehydrogenase (oxidase) 1 2.96379
TDRD1 tudor domain containing 1 2.96379
MINPP1 multiple inositol-polyphosphate phosphatase 1 2.96379
SHE Src homology 2 domain containing E 2.96379
LGI1 leucine-rich, glioma inactivated 1 2.96379
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2.96379
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.96379
SPDYE4 speedy/RINGO cell cycle regulator family member E4 2.96379
CLEC19A C-type lectin domain family 19, member A 2.96379
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.96379
CORO6 coronin 6 2.96379
PAX2 paired box 2 2.96379
FETUB fetuin B 2.96379
GFAP glial fibrillary acidic protein 2.96379
DIO3 deiodinase, iodothyronine, type III 2.96379
CLEC5A C-type lectin domain family 5, member A 2.96379
GPR75 G protein-coupled receptor 75 2.96379
SSU72L3 SSU72 like 3 2.96379
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.96379
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.96379
MYH7 myosin, heavy chain 7, cardiac muscle, beta 2.96379
HTRA4 HtrA serine peptidase 4 2.96379
DUSP1 dual specificity phosphatase 1 2.96379
STMN4 stathmin-like 4 2.96379
TMEM40 transmembrane protein 40 2.96379
MYL10 myosin, light chain 10, regulatory 2.96379
TSPAN8 tetraspanin 8 2.96379
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.96379
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 2.96379
ZNF726 zinc finger protein 726 2.96379
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.96379
CPNE8-AS1 CPNE8 antisense RNA 1 2.96379
ZNF593OS ZNF593 opposite strand 2.96379
RHEX regulator of hemoglobinization and erythroid cell expansion 2.96379
AKAIN1 A-kinase anchor inhibitor 1 2.96379
SPDYE9 speedy/RINGO cell cycle regulator family member E9 2.96379
ELOA2 elongin A2 2.96379
ERFE erythroferrone 2.96379
JAML junction adhesion molecule like 2.96379
TCIM transcriptional and immune response regulator 2.96379
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) 2.96379
HAO2 hydroxyacid oxidase 2 (long chain) 2.96379
FRMD4B FERM domain containing 4B 2.96379
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.96379
SCRT1 scratch family zinc finger 1 2.96379
PTP4A1 protein tyrosine phosphatase type IVA, member 1 2.96379
CKM creatine kinase, muscle 2.96379
HPR haptoglobin-related protein 2.96379
DMP1 dentin matrix acidic phosphoprotein 1 2.96379
ACTL8 actin-like 8 2.96379
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.96379
IZUMO1 izumo sperm-egg fusion 1 2.96379
OR2A1 olfactory receptor, family 2, subfamily A, member 1 2.96379
FPR2 formyl peptide receptor 2 2.96379
SYCP1 synaptonemal complex protein 1 2.96379
IL5 interleukin 5 2.96379
TLR3 toll-like receptor 3 2.96379
HNF1B HNF1 homeobox B 2.96379
LTA lymphotoxin alpha 2.96379
DLK1 delta-like 1 homolog (Drosophila) 2.96379
PNPLA1 patatin-like phospholipase domain containing 1 2.96379
HAL histidine ammonia-lyase 2.96379
PLEK2 pleckstrin 2 2.96379
FGFBP1 fibroblast growth factor binding protein 1 2.96379
SPAG4 sperm associated antigen 4 2.96379
PRR4 proline rich 4 (lacrimal) 2.96379
NPFF neuropeptide FF-amide peptide precursor 2.96379
KCNT1 potassium channel, sodium activated subfamily T, member 1 2.96379
HNF4A hepatocyte nuclear factor 4, alpha 2.96379
RNF39 ring finger protein 39 2.96379
GHR growth hormone receptor 2.96379
PFN4 profilin family, member 4 2.96379
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 2.96379
PCDHGB5 protocadherin gamma subfamily B, 5 2.96379
PCDHGB1 protocadherin gamma subfamily B, 1 2.96379
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2.96379
INSM1 insulinoma-associated 1 2.96379
ERICH4 glutamate-rich 4 2.96379
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 2.96379
EDN3 endothelin 3 2.96379
DYTN dystrotelin 2.96379
TTYH1 tweety family member 1 2.96379
ACKR2 atypical chemokine receptor 2 2.96379
LPAR5 lysophosphatidic acid receptor 5 2.96379
ECM1 extracellular matrix protein 1 2.96379
ACSM5 acyl-CoA synthetase medium-chain family member 5 2.96379
ACSM1 acyl-CoA synthetase medium-chain family member 1 2.96379
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 2.96379
TSPAN32 tetraspanin 32 2.96379
NXNL1 nucleoredoxin-like 1 2.96379
CPO carboxypeptidase O 2.96379
GPR12 G protein-coupled receptor 12 2.96379
TMEM31 transmembrane protein 31 2.96379
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.96379
LRRK2 leucine-rich repeat kinase 2 2.96379
TEX12 testis expressed 12 2.96379
KLK6 kallikrein-related peptidase 6 2.96379
PABPN1L poly(A) binding protein, nuclear 1-like (cytoplasmic) 2.96379
CHIT1 chitinase 1 (chitotriosidase) 2.96379
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.96379
KRT86 keratin 86, type II 2.96379
DMRT1 doublesex and mab-3 related transcription factor 1 2.96379
NRIP2 nuclear receptor interacting protein 2 2.96379
MUC15 mucin 15, cell surface associated 2.96379
S100A14 S100 calcium binding protein A14 2.96379
PRH2 proline-rich protein HaeIII subfamily 2 2.96379
CXCR4 chemokine (C-X-C motif) receptor 4 2.96379
KLF2 Kruppel-like factor 2 2.96379
CRHBP corticotropin releasing hormone binding protein 2.96379
NTN5 netrin 5 2.96379
CALHM1 calcium homeostasis modulator 1 2.96379
BAHCC1 BAH domain and coiled-coil containing 1 2.96379
AGXT2 alanine--glyoxylate aminotransferase 2 2.96379
CSF1R colony stimulating factor 1 receptor 2.96379
GRAP2 GRB2-related adaptor protein 2 2.96379
TGM4 transglutaminase 4 2.96379
CCDC70 coiled-coil domain containing 70 2.96379
HEPN1 hepatocellular carcinoma, down-regulated 1 2.96379
IRX5 iroquois homeobox 5 2.96379
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.96379
MROH2A maestro heat-like repeat family member 2A 2.96379
ANGPTL7 angiopoietin-like 7 2.96379
IL33 interleukin 33 2.96379
OXER1 oxoeicosanoid (OXE) receptor 1 2.96379
GLYATL3 glycine-N-acyltransferase-like 3 2.96379
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.96379
CHRDL2 chordin-like 2 2.96379
VPREB3 pre-B lymphocyte 3 2.96379
CNR2 cannabinoid receptor 2 (macrophage) 2.96379
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.96379
SFN stratifin 2.96379
PROM2 prominin 2 2.96379
MB myoglobin 2.96379
CYSRT1 cysteine-rich tail protein 1 2.96379
PRSS21 protease, serine, 21 (testisin) 2.96379
DRC7 dynein regulatory complex subunit 7 2.96379
ZNF804A zinc finger protein 804A 2.96379
SPAG8 sperm associated antigen 8 2.96379
RBP2 retinol binding protein 2, cellular 2.96379
LPO lactoperoxidase 2.96379
RAB8B RAB8B, member RAS oncogene family 2.95864
IGSF9B immunoglobulin superfamily, member 9B 2.9569
C17ORF114 chromosome 17 open reading frame 114 2.89269
EHD3 EH-domain containing 3 2.89269
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 2.89269
PQBP1 polyglutamine binding protein 1 2.89269
TMED5 transmembrane emp24 protein transport domain containing 5 2.85386
CUZD1 CUB and zona pellucida-like domains 1 2.80724
FBN2 fibrillin 2 2.79346
HEBP1 heme binding protein 1 2.76985
CAPN7 calpain 7 2.74645
WIF1 WNT inhibitory factor 1 2.69968
IZUMO2 IZUMO family member 2 2.65834
IER5 immediate early response 5 2.61056
ZCCHC24 zinc finger, CCHC domain containing 24 2.57627
TBC1D2 TBC1 domain family, member 2 2.56439
AQP5 aquaporin 5 2.53546
FERMT3 fermitin family member 3 2.53211
PCDHA5 protocadherin alpha 5 2.53211
WNK3 WNK lysine deficient protein kinase 3 2.51806
COX5B cytochrome c oxidase subunit Vb 2.51434
CFP complement factor properdin 2.50976
MEI1 meiosis inhibitor 1 2.48677
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 2.48677
CD58 CD58 molecule 2.47679
SYBU syntabulin (syntaxin-interacting) 2.46736
TMEM74B transmembrane protein 74B 2.46736
TTBK1 tau tubulin kinase 1 2.45755
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 2.44643
CBY3 chibby homolog 3 (Drosophila) 2.43828
ERAS ES cell expressed Ras 2.43828
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 2.43828
ECI1 enoyl-CoA delta isomerase 1 2.42409
PLAT plasminogen activator, tissue 2.41313
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.40466
C6ORF141 chromosome 6 open reading frame 141 2.36517
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.35846
DYNLT1 dynein, light chain, Tctex-type 1 2.35846
TTC3 tetratricopeptide repeat domain 3 2.3527
ISG15 ISG15 ubiquitin-like modifier 2.35069
SLC45A4 solute carrier family 45, member 4 2.34962
RHOC ras homolog family member C 2.33296
PBLD phenazine biosynthesis-like protein domain containing 2.33251
MIMS2 mitochondrial inner membrane scaffold 2 2.33251
TNNI3 troponin I type 3 (cardiac) 2.32646
MTCL1 microtubule crosslinking factor 1 2.32275
ACYP1 acylphosphatase 1, erythrocyte (common) type 2.31683
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.30609
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.29941
JARID2 jumonji, AT rich interactive domain 2 2.25463
RPL3 ribosomal protein L3 2.23874
EPHB4 EPH receptor B4 2.23729
ZMIZ1 zinc finger, MIZ-type containing 1 2.23529
SMOX spermine oxidase 2.22864
GPBP1 GC-rich promoter binding protein 1 2.21905
AKAP1 A kinase (PRKA) anchor protein 1 2.21787
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 2.20681
GGNBP2 gametogenetin binding protein 2 2.15812
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 2.15169
CYSTM1 cysteine-rich transmembrane module containing 1 2.14775
SCG3 secretogranin III 2.14261
HMG20A high mobility group 20A 2.13743
SCX scleraxis basic helix-loop-helix transcription factor 2.12888
CLDN6 claudin 6 2.11967
KIF27 kinesin family member 27 2.11967
MRPS21 mitochondrial ribosomal protein S21 2.07172
PHB2 prohibitin 2 2.07172
ATG9A autophagy related 9A 2.07017
ANO1 anoctamin 1, calcium activated chloride channel 2.06428
NR6A1 nuclear receptor subfamily 6, group A, member 1 2.06428
PROSER1 proline and serine rich 1 2.06224
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 2.05554
SGMS2 sphingomyelin synthase 2 2.05502
IRX2 iroquois homeobox 2 2.05024
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 2.03282
CYB5A cytochrome b5 type A (microsomal) 2.02048
SART3 squamous cell carcinoma antigen recognized by T cells 3 2.01601
MARK4 MAP/microtubule affinity-regulating kinase 4 2.01211

decreased expression

Symbol Name Standardized Value
LOC107985101 uncharacterized LOC107985101 -3.09309
SMAD9 SMAD family member 9 -3.09309
NEFH neurofilament, heavy polypeptide -3.09309
TMEM106C transmembrane protein 106C -3.09309
TCL1B T-cell leukemia/lymphoma 1B -3.01922
PABPC4L poly(A) binding protein, cytoplasmic 4-like -3.01922
PPP1R42 protein phosphatase 1, regulatory subunit 42 -3.01922
NEURL1 neuralized E3 ubiquitin protein ligase 1 -3.01922
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) -2.96379
PRKCQ protein kinase C, theta -2.96379
SSBP3 single stranded DNA binding protein 3 -2.96379
GRID2 glutamate receptor, ionotropic, delta 2 -2.96379
AZI2 5-azacytidine induced 2 -2.96379
GPC6 glypican 6 -2.96379
RHEB Ras homolog enriched in brain -2.96379
SLC51A solute carrier family 51, alpha subunit -2.93715
KANK4 KN motif and ankyrin repeat domains 4 -2.93443
LEKR1 leucine, glutamate and lysine rich 1 -2.93443
SPX spexin hormone -2.93443
UNC45B unc-45 homolog B (C. elegans) -2.93443
MROH6 maestro heat-like repeat family member 6 -2.93443
SNAP25 synaptosomal-associated protein, 25kDa -2.93443
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -2.93443
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -2.93443
SYTL4 synaptotagmin-like 4 -2.93443
EYA4 EYA transcriptional coactivator and phosphatase 4 -2.93443
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.93443
AKAP14 A kinase (PRKA) anchor protein 14 -2.93443
INHBC inhibin, beta C -2.93443
SLC35D3 solute carrier family 35, member D3 -2.93443
NHLH1 nescient helix loop helix 1 -2.93443
GPR34 G protein-coupled receptor 34 -2.93443
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 -2.93443
XK X-linked Kx blood group -2.93443
CRHR1 corticotropin releasing hormone receptor 1 -2.93443
CYS1 cystin 1 -2.93443
DCTN4 dynactin 4 (p62) -2.93443
DNAAF19 dynein axonemal assembly factor 19 -2.93443
CCDC194 coiled-coil domain containing 194 -2.93443
G0S2 G0/G1 switch 2 -2.93443
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 -2.93443
DUSP26 dual specificity phosphatase 26 (putative) -2.93443
MZB1 marginal zone B and B1 cell-specific protein -2.93443
SUGCT succinyl-CoA:glutarate-CoA transferase -2.93191
COL2A1 collagen, type II, alpha 1 -2.92978
NPTN neuroplastin -2.91369
MT1F metallothionein 1F -2.89163
ICE2 interactor of little elongation complex ELL subunit 2 -2.85386
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -2.7954
FAM194C family with sequence similarity 149 member C -2.77401
DEGS2 delta(4)-desaturase, sphingolipid 2 -2.77401
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -2.77401
C2ORF81 chromosome 2 open reading frame 81 -2.77401
HRK harakiri, BCL2 interacting protein -2.76301
SH3RF2 SH3 domain containing ring finger 2 -2.76301
PKLR pyruvate kinase, liver and RBC -2.76301
CLK4 CDC-like kinase 4 -2.75409
PHC1 polyhomeotic homolog 1 (Drosophila) -2.74036
PEX11G peroxisomal biogenesis factor 11 gamma -2.73304
RCAN1 regulator of calcineurin 1 -2.72476
LIN28B lin-28 homolog B (C. elegans) -2.66624
PF4 platelet factor 4 -2.61056
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 -2.55175
ADRA2B adrenoceptor alpha 2B -2.52986
NINJ2 ninjurin 2 -2.52986
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -2.48677
STAU1 staufen double-stranded RNA binding protein 1 -2.46926
NT5C3A 5'-nucleotidase, cytosolic IIIA -2.46656
PPP6R2 protein phosphatase 6, regulatory subunit 2 -2.42409
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 -2.42409
ZNF660 zinc finger protein 660 -2.41184
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.37354
ZMIZ2 zinc finger, MIZ-type containing 2 -2.37058
ALG11 ALG11, alpha-1,2-mannosyltransferase -2.36517
ZNF408 zinc finger protein 408 -2.3587
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -2.35846
PGRMC1 progesterone receptor membrane component 1 -2.31683
TAS2R4 taste receptor, type 2, member 4 -2.27917
FBXL16 F-box and leucine-rich repeat protein 16 -2.27917
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -2.26089
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 -2.25463
RFT1 RFT1 homolog (S. cerevisiae) -2.24813
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 -2.23088
TIMELESS timeless circadian clock -2.22627
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -2.21295
CIT citron rho-interacting serine/threonine kinase -2.19851
OR2H2 olfactory receptor, family 2, subfamily H, member 2 -2.19851
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 -2.18303
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -2.18303
SUSD5 sushi domain containing 5 -2.18303
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -2.18303
OXTR oxytocin receptor -2.18303
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -2.17629
BBS10 Bardet-Biedl syndrome 10 -2.17554
NLRP12 NLR family, pyrin domain containing 12 -2.17554
TELO2 telomere maintenance 2 -2.17479
NCKAP5 NCK-associated protein 5 -2.16742
HELLS helicase, lymphoid-specific -2.15812
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -2.15184
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -2.15169
RPRD1B regulation of nuclear pre-mRNA domain containing 1B -2.14775
SNX13 sorting nexin 13 -2.14775
GRIP1 glutamate receptor interacting protein 1 -2.13034
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -2.13034
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -2.11967
GLRX3 glutaredoxin 3 -2.11967
SEPTIN8 septin 8 -2.11967
PSRC1 proline/serine-rich coiled-coil 1 -2.11967
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 -2.11967
NUP214 nucleoporin 214kDa -2.11777
CHRM5 cholinergic receptor, muscarinic 5 -2.11777
ARRDC4 arrestin domain containing 4 -2.11777
PCLO piccolo presynaptic cytomatrix protein -2.09693
SERP1 stress-associated endoplasmic reticulum protein 1 -2.09527
FMN1 formin 1 -2.07712
OSCAR osteoclast associated, immunoglobulin-like receptor -2.05607
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 -2.05204
IRS1 insulin receptor substrate 1 -2.03951
H4C16 H4 histone 16 -2.03891
MPDZ multiple PDZ domain protein -2.02373
ZMYM2 zinc finger, MYM-type 2 -2.02177
ZNF79 zinc finger protein 79 -2.02048
PDE5A phosphodiesterase 5A, cGMP-specific -2.01418
TYK2 tyrosine kinase 2 -2.00847
SOD1 superoxide dismutase 1, soluble -2.00274