SPERMINE Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description A polyazaalkane that is tetradecane in which the carbons at positions 1, 5, 10 and 14 are replaced by nitrogens. Spermine has broad actions on cellular metabolism. (Chemical Entities of Biological Interest Ontology, CHEBI_15746)
External Link https://dgidb.org/results?searchType=drug&searchTerms=SPERMINE
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Genes

9 interacting proteins for the SPERMINE drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.96044
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.735167
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.490111
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.345961
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.261393
CASR calcium-sensing receptor 0.147033
DRD1 dopamine receptor D1 0.032315
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.0123298
EHMT2 euchromatic histone-lysine N-methyltransferase 2 0.00672921