| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | Spi-B transcription factor (Spi-1/PU.1 related)|The protein encoded by this gene is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 6689) |
| External Link | https://ncbi.nlm.nih.gov/gene/6689 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the SPIB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0280714 |
| CA2 | carbonic anhydrase II | 0.0150689 |
| MMP12 | matrix metallopeptidase 12 | 0.0150052 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0142496 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0140103 |
| DCK | deoxycytidine kinase | 0.0137332 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0134101 |
| GLUL | glutamate-ammonia ligase | 0.013105 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0125819 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0125434 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0121347 |
| CCNB1 | cyclin B1 | 0.0120668 |
| CLCA1 | chloride channel accessory 1 | 0.0119441 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.0118016 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.0117595 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0117281 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0117069 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0116732 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0113243 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.0111665 |
| CDC42 | cell division cycle 42 | 0.0111097 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0110907 |
| TMEM14A | transmembrane protein 14A | 0.0110663 |
| TSPAN6 | tetraspanin 6 | 0.0110333 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0109756 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.010871 |
| RPA3 | replication protein A3, 14kDa | 0.0107852 |
| CLDND1 | claudin domain containing 1 | 0.0107393 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0107154 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.0107032 |
| CPE | carboxypeptidase E | 0.0106579 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.0106165 |
| CCNA2 | cyclin A2 | 0.0105031 |
| PTTG1 | pituitary tumor-transforming 1 | 0.0103877 |
| CLEC7A | C-type lectin domain family 7, member A | 0.0103716 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.0102773 |
| RHOB | ras homolog family member B | 0.0101893 |
| TFF1 | trefoil factor 1 | 0.00996939 |
| SDC2 | syndecan 2 | 0.00994647 |
| FCGBP | Fc fragment of IgG binding protein | 0.00994401 |
| COMMD10 | COMM domain containing 10 | 0.00989447 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00985 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00977319 |
| SRP9 | signal recognition particle 9kDa | 0.00973763 |
| PLPP3 | phospholipid phosphatase 3 | 0.00965414 |
| NUP37 | nucleoporin 37kDa | 0.00962887 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00958181 |
| COPS4 | COP9 signalosome subunit 4 | 0.00955605 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00954284 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00951628 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00942722 |
| TMEM50B | transmembrane protein 50B | 0.00939592 |
| ADM | adrenomedullin | 0.00939585 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.0093427 |
| CENPX | centromere protein X | 0.00931698 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00929249 |
| CD69 | CD69 molecule | 0.00925692 |
| PCLAF | PCNA clamp associated factor | 0.00925148 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00924472 |
| SIRT3 | sirtuin 3 | 0.00922601 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00920833 |
| DUT | deoxyuridine triphosphatase | 0.0091998 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00915931 |
| SELENOF | selenoprotein F | 0.00907525 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00904993 |
| TMEM126B | transmembrane protein 126B | 0.00903441 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00901798 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00893274 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00892028 |
| KRT20 | keratin 20, type I | 0.00888793 |
| HMGB2 | high mobility group box 2 | 0.0088417 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.0088377 |
| RANBP1 | RAN binding protein 1 | 0.00882584 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00880536 |
| ATG5 | autophagy related 5 | 0.00877791 |
| OIP5 | Opa interacting protein 5 | 0.00876907 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.00873511 |
| ACTB | actin, beta | 0.00870393 |
| TSPAN5 | tetraspanin 5 | 0.00869765 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.00864461 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 0.00858889 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00858633 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0085009 |
| TMEM176B | transmembrane protein 176B | 0.00848349 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00847736 |
| EVI2A | ecotropic viral integration site 2A | 0.00846642 |
| NMU | neuromedin U | 0.00845558 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00843359 |
| MRPL42 | mitochondrial ribosomal protein L42 | 0.00841081 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00839059 |
| AOC1 | amine oxidase, copper containing 1 | 0.00838482 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.0083747 |
| TMEM230 | transmembrane protein 230 | 0.00835939 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.00830562 |
| EXOC5 | exocyst complex component 5 | 0.00828104 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00826456 |
| TYMS | thymidylate synthetase | 0.00826442 |
| SRP72 | signal recognition particle 72kDa | 0.00823767 |
| FGL2 | fibrinogen-like 2 | 0.00821013 |
| GLO1 | glyoxalase I | 0.0082069 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.0082047 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00819146 |
| NMD3 | NMD3 ribosome export adaptor | 0.00818626 |
| CD99 | CD99 molecule | 0.00817195 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00817158 |
| CLEC4A | C-type lectin domain family 4, member A | 0.00814558 |
| AURKB | aurora kinase B | 0.00814328 |
| CALD1 | caldesmon 1 | 0.00813228 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00812514 |
| TRAM1 | translocation associated membrane protein 1 | 0.00812353 |
| PBK | PDZ binding kinase | 0.00809946 |
| GCH1 | GTP cyclohydrolase 1 | 0.00808572 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00806538 |
| SELENOT | selenoprotein T | 0.00806298 |
| TPM4 | tropomyosin 4 | 0.00805284 |
| SORD | sorbitol dehydrogenase | 0.00801226 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00800058 |
| FAM198B | family with sequence similarity 198, member B | 0.0080003 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00799964 |
| PON3 | paraoxonase 3 | 0.00798721 |
| CA9 | carbonic anhydrase IX | 0.0079781 |
| ITGA6 | integrin, alpha 6 | 0.00797039 |
| TMEM176A | transmembrane protein 176A | 0.0079391 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00793321 |
| COMMD8 | COMM domain containing 8 | 0.0079271 |
| OLFM4 | olfactomedin 4 | 0.0079257 |
| CDK1 | cyclin-dependent kinase 1 | 0.00790983 |
| LYZ | lysozyme | 0.00790069 |
| TPD52L1 | tumor protein D52-like 1 | 0.00788692 |
| RCAN2 | regulator of calcineurin 2 | 0.00786927 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0078401 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.0078401 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00783842 |
| CD2 | CD2 molecule | 0.00783535 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00781333 |
| RHOA | ras homolog family member A | 0.00774861 |
| LMNB1 | lamin B1 | 0.00773256 |
| PRDX2 | peroxiredoxin 2 | 0.00772608 |
| RPS5 | ribosomal protein S5 | 0.00771243 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.0076898 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00766936 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00766847 |
| ATF1 | activating transcription factor 1 | 0.00764134 |
| GFAP | glial fibrillary acidic protein | 0.00763495 |
| REEP5 | receptor accessory protein 5 | 0.00760286 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.00756738 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00756395 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00754525 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00753197 |
| PRDX4 | peroxiredoxin 4 | 0.00751341 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.0075101 |
| MRPL39 | mitochondrial ribosomal protein L39 | 0.00750035 |
| PLS3 | plastin 3 | 0.00749797 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00747763 |
| CRLF3 | cytokine receptor-like factor 3 | 0.00745827 |
| CNTNAP2 | contactin associated protein-like 2 | 0.00743926 |
| PGD | phosphogluconate dehydrogenase | 0.00743725 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00741997 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00741621 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00740544 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.0073965 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00738889 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00738613 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00737459 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00737322 |
| PDCD10 | programmed cell death 10 | 0.00734585 |
| DAZAP2 | DAZ associated protein 2 | 0.0073383 |
| TMEM14B | transmembrane protein 14B | 0.00733452 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00732488 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00731359 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0073108 |
| STMN1 | stathmin 1 | 0.00729395 |
| ARMC1 | armadillo repeat containing 1 | 0.00729229 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00728207 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.0072813 |
| SNX7 | sorting nexin 7 | 0.00727935 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.00724989 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0072468 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00717789 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.00716577 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | 0.00716196 |
| COMP | cartilage oligomeric matrix protein | 0.00716178 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.0071558 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 0.00714916 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00712517 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00712455 |
| PDAP1 | PDGFA associated protein 1 | 0.00707811 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00705597 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00705515 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00705212 |
| LMAN1 | lectin, mannose-binding, 1 | 0.00703978 |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 | 0.00703014 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00702674 |
| CAPRIN1 | cell cycle associated protein 1 | 0.00701747 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | 0.00700822 |
| S100A10 | S100 calcium binding protein A10 | 0.00699436 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00698958 |
| GPX2 | glutathione peroxidase 2 | 0.00698721 |
| H2AX | H2A.X variant histone | 0.00696943 |
| ZNF652 | zinc finger protein 652 | 0.00693813 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00692373 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00692342 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.0069136 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.00688942 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00688116 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.0068781 |
| CNN3 | calponin 3, acidic | 0.0068774 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00687043 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | 0.00685531 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00683898 |
| MRPL40 | mitochondrial ribosomal protein L40 | 0.00683222 |
| HOPX | HOP homeobox | 0.00682679 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00682507 |
| ACP6 | acid phosphatase 6, lysophosphatidic | 0.00681977 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 0.00681944 |
| FPR1 | formyl peptide receptor 1 | 0.00681891 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00681752 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00681148 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00679553 |
| RNF14 | ring finger protein 14 | 0.00678418 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0067624 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00676107 |
| CTSZ | cathepsin Z | 0.00675758 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00675717 |
| FOXF1 | forkhead box F1 | 0.0067483 |
| HEBP2 | heme binding protein 2 | 0.00674783 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | 0.00673963 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.00673856 |
| CLCA4 | chloride channel accessory 4 | 0.00673458 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00673004 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.00672968 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0067263 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 0.00671675 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00669398 |
| DUOX2 | dual oxidase 2 | 0.00667971 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00667945 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00667445 |
| MPC2 | mitochondrial pyruvate carrier 2 | 0.00666942 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.00666775 |
| NEK2 | NIMA-related kinase 2 | 0.00666256 |
| IFNGR1 | interferon gamma receptor 1 | 0.00666042 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00665611 |
| REG1A | regenerating islet-derived 1 alpha | 0.00664888 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00662813 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00662394 |
| TSPAN13 | tetraspanin 13 | 0.00660765 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00660322 |
| TMEM106B | transmembrane protein 106B | 0.00659891 |
| TMEM38B | transmembrane protein 38B | 0.00659839 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.0065884 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | -0.0175083 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0173624 |
| MX1 | MX dynamin-like GTPase 1 | -0.0171243 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.0161086 |
| SRPX | sushi-repeat containing protein, X-linked | -0.0160605 |
| OXTR | oxytocin receptor | -0.0150997 |
| APOD | apolipoprotein D | -0.0146333 |
| KRT14 | keratin 14, type I | -0.0144947 |
| MSLN | mesothelin | -0.0143564 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0140824 |
| MGLL | monoglyceride lipase | -0.0133484 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0132296 |
| NVL | nuclear VCP-like | -0.0129547 |
| CHRDL1 | chordin-like 1 | -0.0129463 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0125684 |
| MT1X | metallothionein 1X | -0.0123441 |
| SLC43A3 | solute carrier family 43, member 3 | -0.0119107 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.0117604 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0116494 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0115944 |
| C3 | complement component 3 | -0.011408 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0113402 |
| CFB | complement factor B | -0.0113295 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.0113077 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0112272 |
| MEIS1 | Meis homeobox 1 | -0.0111641 |
| IRS2 | insulin receptor substrate 2 | -0.0111515 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0109872 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.0109529 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.010788 |
| BTG2 | BTG family, member 2 | -0.010775 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0107269 |
| BST2 | bone marrow stromal cell antigen 2 | -0.010587 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0104896 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0104557 |
| GSDME | gasdermin E | -0.0103937 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0102985 |
| MX2 | MX dynamin-like GTPase 2 | -0.0101903 |
| KRT23 | keratin 23, type I | -0.0101143 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0100872 |
| TNS1 | tensin 1 | -0.0100438 |
| TSPYL5 | TSPY-like 5 | -0.00997712 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00996652 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00996553 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00977609 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00975016 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00974602 |
| MVP | major vault protein | -0.00969136 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00955713 |
| LAMC2 | laminin, gamma 2 | -0.00949832 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00946893 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0094026 |
| IER5 | immediate early response 5 | -0.00937727 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0093369 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00920219 |
| MUC16 | mucin 16, cell surface associated | -0.00916271 |
| TGFA | transforming growth factor, alpha | -0.00913538 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00907999 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00906481 |
| SYNM | synemin, intermediate filament protein | -0.00902105 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00895529 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00882065 |
| KLK11 | kallikrein-related peptidase 11 | -0.00878702 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00878082 |
| MMP1 | matrix metallopeptidase 1 | -0.00875043 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00873834 |
| RRAD | Ras-related associated with diabetes | -0.00873619 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00865741 |
| MAOB | monoamine oxidase B | -0.00863314 |
| MMP7 | matrix metallopeptidase 7 | -0.00857176 |
| INAVA | innate immunity activator | -0.00854845 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00853167 |
| CES1 | carboxylesterase 1 | -0.00847844 |
| MPDZ | multiple PDZ domain protein | -0.00845454 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00841476 |
| HMOX1 | heme oxygenase 1 | -0.00833936 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.0083139 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00830745 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00829287 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00828908 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00822329 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00821619 |
| RCAN1 | regulator of calcineurin 1 | -0.00820433 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00819542 |
| GPX7 | glutathione peroxidase 7 | -0.00817239 |
| KRT15 | keratin 15, type I | -0.00816739 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00813554 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00812015 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00810238 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | -0.00809786 |
| BCHE | butyrylcholinesterase | -0.00809033 |
| PALMD | palmdelphin | -0.00808747 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.00807795 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00807473 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00804914 |
| CRYAB | crystallin, alpha B | -0.00803562 |
| ADCY9 | adenylate cyclase 9 | -0.00802467 |
| NAV2 | neuron navigator 2 | -0.00798449 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | -0.0079806 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00797827 |
| SVIL | supervillin | -0.00797245 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.00790953 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00790227 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00787963 |
| WT1 | Wilms tumor 1 | -0.00786293 |
| SMAD3 | SMAD family member 3 | -0.00785555 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | -0.00785474 |
| RRBP1 | ribosome binding protein 1 | -0.00783149 |
| AFF1 | AF4/FMR2 family, member 1 | -0.00782522 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00782506 |
| TICAM1 | toll-like receptor adaptor molecule 1 | -0.00767265 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00766768 |
| GRN | granulin | -0.00760209 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00759974 |
| RET | ret proto-oncogene | -0.00756191 |
| HEATR1 | HEAT repeat containing 1 | -0.00754869 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00753401 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00752814 |
| NFIB | nuclear factor I/B | -0.00751421 |
| S100A11 | S100 calcium binding protein A11 | -0.00749663 |
| TAPBP | TAP binding protein (tapasin) | -0.00748011 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00747835 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00744627 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00742723 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00739911 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00739542 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00739276 |
| MIA | melanoma inhibitory activity | -0.00735115 |
| RUNX3 | runt-related transcription factor 3 | -0.00734937 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00734774 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.00732117 |
| CCND3 | cyclin D3 | -0.00731147 |
| DEFB1 | defensin, beta 1 | -0.00729534 |
| PROM1 | prominin 1 | -0.00729501 |
| NXN | nucleoredoxin | -0.00725438 |
| KRT7 | keratin 7, type II | -0.00722677 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -0.0072096 |
| IL6R | interleukin 6 receptor | -0.0071963 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00717882 |
| RAI2 | retinoic acid induced 2 | -0.00714988 |
| EGR1 | early growth response 1 | -0.00714929 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00714881 |
| KLHL21 | kelch-like family member 21 | -0.00712109 |
| ETV5 | ets variant 5 | -0.00709032 |
| SOAT1 | sterol O-acyltransferase 1 | -0.00708796 |
| HOMER1 | homer scaffolding protein 1 | -0.00707168 |
| ASRGL1 | asparaginase like 1 | -0.00707127 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00705857 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00705785 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0070517 |
| BMS1 | BMS1 ribosome biogenesis factor | -0.00705012 |
| STK10 | serine/threonine kinase 10 | -0.00704967 |
| IFI44L | interferon-induced protein 44-like | -0.00700032 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00699724 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.0069852 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00698399 |
| KLC1 | kinesin light chain 1 | -0.00697474 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00697277 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00696189 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00695892 |
| MOK | MOK protein kinase | -0.0069348 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00693408 |
| ESR1 | estrogen receptor 1 | -0.00693297 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00692044 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00691399 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00690919 |
| COL4A1 | collagen, type IV, alpha 1 | -0.00690334 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00690027 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00689497 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.00688963 |
| PLA1A | phospholipase A1 member A | -0.00688064 |
| NID1 | nidogen 1 | -0.00687858 |
| TP53BP1 | tumor protein p53 binding protein 1 | -0.0068672 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00684919 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0068347 |
| CCN2 | cellular communication network factor 2 | -0.00681934 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00681347 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00678495 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00677598 |
| PTN | pleiotrophin | -0.00677531 |
| JMJD6 | jumonji domain containing 6 | -0.00674219 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00673518 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00673264 |
| ADRB2 | adrenoceptor beta 2, surface | -0.00671987 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.00669212 |
| MT1H | metallothionein 1H | -0.00669067 |
| RRAGD | Ras-related GTP binding D | -0.00668617 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00668157 |
| VGLL4 | vestigial-like family member 4 | -0.00667571 |
| WFS1 | Wolfram syndrome 1 (wolframin) | -0.00667109 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00666937 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00666168 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00664736 |
| SP110 | SP110 nuclear body protein | -0.00663607 |
| TUBB6 | tubulin, beta 6 class V | -0.00662213 |
| HOMER3 | homer scaffolding protein 3 | -0.00658723 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.00657901 |
| GAS1 | growth arrest-specific 1 | -0.00657299 |
| AOC3 | amine oxidase, copper containing 3 | -0.00657268 |
| MEIS2 | Meis homeobox 2 | -0.00657151 |
| WDTC1 | WD and tetratricopeptide repeats 1 | -0.00654871 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | -0.00654281 |
| PNMA8A | PNMA family member 8A | -0.00654125 |
| TRIM8 | tripartite motif containing 8 | -0.00652459 |
| CTPS1 | CTP synthase 1 | -0.0065153 |
| RBPMS | RNA binding protein with multiple splicing | -0.00650009 |
| LONP1 | lon peptidase 1, mitochondrial | -0.00648236 |
| SFXN3 | sideroflexin 3 | -0.0064761 |
| NPR1 | natriuretic peptide receptor 1 | -0.00647506 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.00647471 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00646433 |
| PRRC2C | proline-rich coiled-coil 2C | -0.006454 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.00645249 |
| GPR137B | G protein-coupled receptor 137B | -0.0064514 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00644774 |
| IL6 | interleukin 6 | -0.00643594 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0064274 |
| INHBA | inhibin, beta A | -0.00641344 |
| ELAC2 | elaC ribonuclease Z 2 | -0.00640597 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00639645 |
| PUM3 | pumilio RNA binding family member 3 | -0.00639333 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00639227 |
| MCOLN1 | mucolipin 1 | -0.00638752 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | -0.00638283 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.00638106 |
| COL1A1 | collagen, type I, alpha 1 | -0.00636986 |
| DPT | dermatopontin | -0.00635635 |
| CPM | carboxypeptidase M | -0.00634599 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00633947 |
| CTSA | cathepsin A | -0.00633672 |
| FOXJ3 | forkhead box J3 | -0.00633278 |
| MT1G | metallothionein 1G | -0.00632439 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00632319 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00629786 |
| EHD3 | EH-domain containing 3 | -0.00629311 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.00628548 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.00625913 |
| MAGED1 | melanoma antigen family D1 | -0.00625571 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.00624435 |
| YY1AP1 | YY1 associated protein 1 | -0.00623805 |
| TMEM255A | transmembrane protein 255A | -0.00621594 |
| VLDLR | very low density lipoprotein receptor | -0.00620982 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00620609 |
| MCAM | melanoma cell adhesion molecule | -0.00620459 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | -0.00619502 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00619434 |
| ENAH | enabled homolog (Drosophila) | -0.00618933 |
| SIRPA | signal-regulatory protein alpha | -0.00618549 |
| RNF167 | ring finger protein 167 | -0.00617382 |
| IPO13 | importin 13 | -0.00617319 |
