SPINK1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description serine peptidase inhibitor, Kazal type 1|The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 6690)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_SPINK1
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Genes

27 co-expressed genes for SPINK1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
CEL carboxyl ester lipase
CELA2A chymotrypsin-like elastase family, member 2A
CELA3A chymotrypsin-like elastase family, member 3A
CELA3B chymotrypsin-like elastase family, member 3B
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLPS colipase, pancreatic
CPA1 carboxypeptidase A1 (pancreatic)
CPA2 carboxypeptidase A2 (pancreatic)
CPB1 carboxypeptidase B1 (tissue)
CTRB1 chymotrypsinogen B1
CTRC chymotrypsin C (caldecrin)
CTRL chymotrypsin-like
CUZD1 CUB and zona pellucida-like domains 1
GP2 glycoprotein 2 (zymogen granule membrane)
PDIA2 protein disulfide isomerase family A, member 2
PLA2G1B phospholipase A2, group IB (pancreas)
PNLIP pancreatic lipase
PNLIPRP1 pancreatic lipase-related protein 1
PNLIPRP2 pancreatic lipase-related protein 2
PRSS1 protease, serine, 1 (trypsin 1)
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
PRSS3P2 protease, serine, 3 pseudogene 2
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SPINK1 serine peptidase inhibitor, Kazal type 1