SPPL2A Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description signal peptide peptidase like 2A|This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012] (NCBI Entrez Gene Database, 84888)
External Link http://www.ncbi.nlm.nih.gov/gene/84888
Similar Terms
Downloads & Tools

Genes

47 interacting proteins for SPPL2A from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADGRL4 adhesion G protein-coupled receptor L4
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BSG basigin (Ok blood group)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD47 CD47 molecule
CD59 CD59 molecule, complement regulatory protein
CD63 CD63 molecule
CLDND1 claudin domain containing 1
EMP1 epithelial membrane protein 1
EMP3 epithelial membrane protein 3
FAP fibroblast activation protein, alpha
GLMP glycosylated lysosomal membrane protein
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
ICAM2 intercellular adhesion molecule 2
IL13RA2 interleukin 13 receptor, alpha 2
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LNPEP leucyl/cystinyl aminopeptidase
MPZL1 myelin protein zero-like 1
MPZL2 myelin protein zero-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPC1 Niemann-Pick disease, type C1
NPTN neuroplastin
PPAP2C phosphatidic acid phosphatase type 2C
PRNP prion protein
PTPRJ protein tyrosine phosphatase, receptor type, J
SCARB2 scavenger receptor class B, member 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC43A3 solute carrier family 43, member 3
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SYPL1 synaptophysin-like 1
TFRC transferrin receptor
TMEM181 transmembrane protein 181
TMEM206 transmembrane protein 206
TMEM87A transmembrane protein 87A
TSPAN3 tetraspanin 3