SR-95531-1316 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the SR-95531-1316 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARFRP1 ADP-ribosylation factor related protein 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BAHCC1 BAH domain and coiled-coil containing 1
BBS7 Bardet-Biedl syndrome 7
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2L1 BCL2-like 1
BLVRA biliverdin reductase A
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C22ORF29 chromosome 22 open reading frame 29
CAMKMT calmodulin-lysine N-methyltransferase
CDCP1 CUB domain containing protein 1
CHML choroideremia-like (Rab escort protein 2)
CHMP6 charged multivesicular body protein 6
CLGN calmegin
CTSL cathepsin L
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DENND1A DENN/MADD domain containing 1A
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DUSP1 dual specificity phosphatase 1
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FCMR Fc fragment of IgM receptor
FUZ fuzzy planar cell polarity protein
GIMAP6 GTPase, IMAP family member 6
GK3P glycerol kinase 3 pseudogene
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HEMK1 HemK methyltransferase family member 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIPK3 homeodomain interacting protein kinase 3
HK2 hexokinase 2
HLA-DMA major histocompatibility complex, class II, DM alpha
HSPA4 heat shock 70kDa protein 4
ICOSLG inducible T-cell co-stimulator ligand
IL11RA interleukin 11 receptor, alpha
IL24 interleukin 24
IRF8 interferon regulatory factor 8
KCTD2 potassium channel tetramerization domain containing 2
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMP5 lysosomal-associated membrane protein family, member 5
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPAR1 lysophosphatidic acid receptor 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
NADK NAD kinase
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NRCAM neuronal cell adhesion molecule
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDLIM7 PDZ and LIM domain 7 (enigma)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMFBP1 polyamine modulated factor 1 binding protein 1
PMM2 phosphomannomutase 2
PYCR1 pyrroline-5-carboxylate reductase 1
QTRT1 queuine tRNA-ribosyltransferase 1
RBKS ribokinase
RCAN1 regulator of calcineurin 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPAIN RPA interacting protein
RPL13P5 ribosomal protein L13 pseudogene 5
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SRR serine racemase
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STARD13 StAR-related lipid transfer (START) domain containing 13
STAT5A signal transducer and activator of transcription 5A
STK16 serine/threonine kinase 16
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TEC tec protein tyrosine kinase
THBS1 thrombospondin 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRA T cell receptor alpha locus
TRAF1 TNF receptor-associated factor 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE3A ubiquitin protein ligase E3A
UPB1 ureidopropionase, beta
USF2 upstream transcription factor 2, c-fos interacting
VCAN versican
VDAC3 voltage-dependent anion channel 3
VNN2 vanin 2
WT1 Wilms tumor 1
XAF1 XIAP associated factor 1
ZDHHC17 zinc finger, DHHC-type containing 17
ZMYM6 zinc finger, MYM-type 6
ZMYND8 zinc finger, MYND-type containing 8
ZNF37BP zinc finger protein 37B, pseudogene
ZNF473 zinc finger protein 473
ZNF668 zinc finger protein 668
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
AKTIP AKT interacting protein
ALPK1 alpha-kinase 1
ANO10 anoctamin 10
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARMC6 armadillo repeat containing 6
BAD BCL2-associated agonist of cell death
BATF basic leucine zipper transcription factor, ATF-like
BRMS1 breast cancer metastasis suppressor 1
BTBD18 BTB (POZ) domain containing 18
C1ORF35 chromosome 1 open reading frame 35
C5AR1 complement component 5a receptor 1
C6ORF47 chromosome 6 open reading frame 47
C8ORF44 chromosome 8 open reading frame 44
CBX7 chromobox homolog 7
CBY1 chibby homolog 1 (Drosophila)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK3 cyclin-dependent kinase 3
CECR1 cat eye syndrome chromosome region, candidate 1
CEP97 centrosomal protein 97kDa
CINP cyclin-dependent kinase 2 interacting protein
CLCN6 chloride channel, voltage-sensitive 6
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
COL9A2 collagen, type IX, alpha 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DNAL4 dynein, axonemal, light chain 4
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DVL1 dishevelled segment polarity protein 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECHDC2 enoyl CoA hydratase domain containing 2
EPHB6 EPH receptor B6
ERCC6L excision repair cross-complementation group 6-like
EXD2 exonuclease 3'-5' domain containing 2
FAM63A family with sequence similarity 63, member A
FHIT fragile histidine triad
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCH1 GTP cyclohydrolase 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPN2 GPN-loop GTPase 2
GPR65 G protein-coupled receptor 65
GRAMD1B GRAM domain containing 1B
GSTM2 glutathione S-transferase mu 2 (muscle)
HHLA3 HERV-H LTR-associating 3
HPSE heparanase
HS1BP3 HCLS1 binding protein 3
HYAL3 hyaluronoglucosaminidase 3
INPPL1 inositol polyphosphate phosphatase-like 1
IRX5 iroquois homeobox 5
LHFP lipoma HMGIC fusion partner
LIMD2 LIM domain containing 2
LMAN2L lectin, mannose-binding 2-like
MAGOHB mago-nashi homolog B (Drosophila)
MBD5 methyl-CpG binding domain protein 5
MED15 mediator complex subunit 15
MOGS mannosyl-oligosaccharide glucosidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYO19 myosin XIX
NINJ1 ninjurin 1
NMB neuromedin B
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5M 5',3'-nucleotidase, mitochondrial
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PHC1 polyhomeotic homolog 1 (Drosophila)
PKN1 protein kinase N1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLS1 plastin 1
POLH polymerase (DNA directed), eta
PTTG3P pituitary tumor-transforming 3, pseudogene
RBL1 retinoblastoma-like 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHOBTB1 Rho-related BTB domain containing 1
RNF25 ring finger protein 25
RPL23AP7 ribosomal protein L23a pseudogene 7
SAP30L SAP30-like
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SMA4 glucuronidase, beta pseudogene
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
SYNJ2BP synaptojanin 2 binding protein
TCEA2 transcription elongation factor A (SII), 2
THBS3 thrombospondin 3
TJP2 tight junction protein 2
TOLLIP toll interacting protein
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
ZBTB3 zinc finger and BTB domain containing 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZMAT5 zinc finger, matrin-type 5
ZNF222 zinc finger protein 222
ZNF350 zinc finger protein 350
ZNF506 zinc finger protein 506