SR-95531-4236 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the SR-95531-4236 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACTN2 actinin, alpha 2
ADAP2 ArfGAP with dual PH domains 2
ADGRL3 adhesion G protein-coupled receptor L3
APLP2 amyloid beta (A4) precursor-like protein 2
APOE apolipoprotein E
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARNT aryl hydrocarbon receptor nuclear translocator
ATXN2L ataxin 2-like
ATXN7L1 ataxin 7-like 1
BCL2 B-cell CLL/lymphoma 2
BMP7 bone morphogenetic protein 7
BTBD18 BTB (POZ) domain containing 18
C18ORF25 chromosome 18 open reading frame 25
C1ORF54 chromosome 1 open reading frame 54
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CD248 CD248 molecule, endosialin
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEMIP cell migration inducing protein, hyaluronan binding
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
COL21A1 collagen, type XXI, alpha 1
COL4A6 collagen, type IV, alpha 6
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CXXC4 CXXC finger protein 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCTN2 dynactin 2 (p50)
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DLL3 delta-like 3 (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DTX2 deltex 2, E3 ubiquitin ligase
EGR1 early growth response 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FETUB fetuin B
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FKRP fukutin related protein
FRMD4B FERM domain containing 4B
GGTLC1 gamma-glutamyltransferase light chain 1
GK3P glycerol kinase 3 pseudogene
GLRA1 glycine receptor, alpha 1
GLRA2 glycine receptor, alpha 2
GP6 glycoprotein VI (platelet)
GRIK5 glutamate receptor, ionotropic, kainate 5
HABP4 hyaluronan binding protein 4
HAP1 huntingtin-associated protein 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HEMK1 HemK methyltransferase family member 1
HOXA1 homeobox A1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LTK leukocyte receptor tyrosine kinase
LYRM9 LYR motif containing 9
MAPK10 mitogen-activated protein kinase 10
MST1 macrophage stimulating 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOL12 nucleolar protein 12
NPTX1 neuronal pentraxin I
NR1H4 nuclear receptor subfamily 1, group H, member 4
OCLM oculomedin
OSBPL10 oxysterol binding protein-like 10
OXCT2 3-oxoacid CoA transferase 2
PBX2 pre-B-cell leukemia homeobox 2
PITX2 paired-like homeodomain 2
PKNOX2 PBX/knotted 1 homeobox 2
PKP4 plakophilin 4
PLK3 polo-like kinase 3
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PTBP3 polypyrimidine tract binding protein 3
PTK2B protein tyrosine kinase 2 beta
PTPRJ protein tyrosine phosphatase, receptor type, J
REPS1 RALBP1 associated Eps domain containing 1
RGS5 regulator of G-protein signaling 5
RHBDD3 rhomboid domain containing 3
RPS14 ribosomal protein S14
SELPLG selectin P ligand
SLC35F5 solute carrier family 35, member F5
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SUGP1 SURP and G patch domain containing 1
SYT2 synaptotagmin II
TAT tyrosine aminotransferase
TBX1 T-box 1
TGS1 trimethylguanosine synthase 1
THBD thrombomodulin
TLK1 tousled-like kinase 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRGV5 T cell receptor gamma variable 5
TXK TXK tyrosine kinase
UBOX5 U-box domain containing 5
ZNF137P zinc finger protein 137, pseudogene
ZNF219 zinc finger protein 219
ZNF287 zinc finger protein 287
ZNF334 zinc finger protein 334
ZNF500 zinc finger protein 500
ZNF507 zinc finger protein 507
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALOX12 arachidonate 12-lipoxygenase
ANKRD36 ankyrin repeat domain 36
ANXA2P1 annexin A2 pseudogene 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMCX2 armadillo repeat containing, X-linked 2
ATF7IP2 activating transcription factor 7 interacting protein 2
BFSP1 beaded filament structural protein 1, filensin
C14ORF105 chromosome 14 open reading frame 105
C19ORF40 chromosome 19 open reading frame 40
C22ORF46 chromosome 22 open reading frame 46
C7ORF69 chromosome 7 open reading frame 69
CAPN15 calpain 15
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CIDEB cell death-inducing DFFA-like effector b
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNGB3 cyclic nucleotide gated channel beta 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
CXCR2 chemokine (C-X-C motif) receptor 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DOK5 docking protein 5
DSPP dentin sialophosphoprotein
EDAR ectodysplasin A receptor
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM120C family with sequence similarity 120C
FRMPD1 FERM and PDZ domain containing 1
GRM4 glutamate receptor, metabotropic 4
HAMP hepcidin antimicrobial peptide
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST2H2AA3 histone cluster 2, H2aa3
HPR haptoglobin-related protein
IL12RB1 interleukin 12 receptor, beta 1
IL2 interleukin 2
IL36RN interleukin 36 receptor antagonist
IRF2BP1 interferon regulatory factor 2 binding protein 1
JUNB jun B proto-oncogene
KANSL3 KAT8 regulatory NSL complex subunit 3
KIAA1456 KIAA1456
KIRREL kin of IRRE like (Drosophila)
KLF13 Kruppel-like factor 13
LIME1 Lck interacting transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LTC4S leukotriene C4 synthase
LY6D lymphocyte antigen 6 complex, locus D
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MFGE8 milk fat globule-EGF factor 8 protein
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTA2 metastasis associated 1 family, member 2
MTSS1L metastasis suppressor 1-like
MYO15A myosin XVA
MYO1D myosin ID
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
OCLN occludin
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBP2 oxysterol binding protein 2
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHEX phosphate regulating endopeptidase homolog, X-linked
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRM2 protamine 2
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3A RAB3A, member RAS oncogene family
RAPSN receptor-associated protein of the synapse
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RNF39 ring finger protein 39
RPP25 ribonuclease P/MRP 25kDa subunit
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC16A6 solute carrier family 16, member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMR3A submaxillary gland androgen regulated protein 3A
SOX12 SRY (sex determining region Y)-box 12
SPTBN2 spectrin, beta, non-erythrocytic 2
SRD5A3 steroid 5 alpha-reductase 3
SSBP3 single stranded DNA binding protein 3
STX5 syntaxin 5
TBC1D17 TBC1 domain family, member 17
TBC1D22B TBC1 domain family, member 22B
TIGD6 tigger transposable element derived 6
TLN1 talin 1
TMEM212 transmembrane protein 212
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNS2 tensin 2
TSNAXIP1 translin-associated factor X interacting protein 1
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
WNT1 wingless-type MMTV integration site family, member 1
XAB2 XPA binding protein 2
ZNF580 zinc finger protein 580
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2