SR-95639A-4977 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the SR-95639A-4977 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRA1A adrenoceptor alpha 1A
AGFG2 ArfGAP with FG repeats 2
AHI1 Abelson helper integration site 1
AK1 adenylate kinase 1
AK2 adenylate kinase 2
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APC adenomatous polyposis coli
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BBC3 BCL2 binding component 3
BMP4 bone morphogenetic protein 4
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CABIN1 calcineurin binding protein 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CASKIN2 CASK interacting protein 2
CD52 CD52 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD82 CD82 molecule
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL5A2 collagen, type V, alpha 2
DAPK3 death-associated protein kinase 3
DFNB31 deafness, autosomal recessive 31
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
DOCK6 dedicator of cytokinesis 6
DPY19L1P1 DPY19L1 pseudogene 1
DVL3 dishevelled segment polarity protein 3
EDAR ectodysplasin A receptor
ELK1 ELK1, member of ETS oncogene family
ENO3 enolase 3 (beta, muscle)
EPHB6 EPH receptor B6
FAM134B family with sequence similarity 134, member B
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAMT guanidinoacetate N-methyltransferase
GSTTP1 glutathione S-transferase theta pseudogene 1
HIPK2 homeodomain interacting protein kinase 2
HIRA histone cell cycle regulator
HOMER3 homer scaffolding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KMT2A lysine (K)-specific methyltransferase 2A
LEPR leptin receptor
LIF leukemia inhibitory factor
LOC440895 two pore channel 3 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LTBP4 latent transforming growth factor beta binding protein 4
MAP1S microtubule-associated protein 1S
MAP2K5 mitogen-activated protein kinase kinase 5
MC5R melanocortin 5 receptor
MIA3 melanoma inhibitory activity family, member 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOBP myelin-associated oligodendrocyte basic protein
MTCP1 mature T-cell proliferation 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NFIB nuclear factor I/B
NID1 nidogen 1
NLE1 notchless homolog 1 (Drosophila)
NME5 NME/NM23 family member 5
NOP16 NOP16 nucleolar protein
NR4A1 nuclear receptor subfamily 4, group A, member 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCNX pecanex homolog (Drosophila)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTGIS prostaglandin I2 (prostacyclin) synthase
RARG retinoic acid receptor, gamma
RIMS2 regulating synaptic membrane exocytosis 2
RIMS3 regulating synaptic membrane exocytosis 3
RPLP2 ribosomal protein, large, P2
RSU1 Ras suppressor protein 1
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
SAYSD1 SAYSVFN motif domain containing 1
SECTM1 secreted and transmembrane 1
SIDT2 SID1 transmembrane family, member 2
SMG7 SMG7 nonsense mediated mRNA decay factor
STEAP4 STEAP family member 4
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SZT2 seizure threshold 2 homolog (mouse)
THOC5 THO complex 5
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPMT thiopurine S-methyltransferase
TRIM29 tripartite motif containing 29
UBQLN4 ubiquilin 4
ULBP1 UL16 binding protein 1
USP19 ubiquitin specific peptidase 19
ZFAND5 zinc finger, AN1-type domain 5
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF493 zinc finger protein 493
ZNF783 zinc finger family member 783
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AMT aminomethyltransferase
BIRC3 baculoviral IAP repeat containing 3
C14ORF93 chromosome 14 open reading frame 93
C5ORF45 chromosome 5 open reading frame 45
CASZ1 castor zinc finger 1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD34 CD34 molecule
CDK20 cyclin-dependent kinase 20
CGA glycoprotein hormones, alpha polypeptide
CHRM3 cholinergic receptor, muscarinic 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLDN1 claudin 1
COCH cochlin
CRIP1 cysteine-rich protein 1 (intestinal)
CST6 cystatin E/M
DGKD diacylglycerol kinase, delta 130kDa
DGKE diacylglycerol kinase, epsilon 64kDa
DRD1 dopamine receptor D1
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ETNK2 ethanolamine kinase 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FILIP1L filamin A interacting protein 1-like
FRMD1 FERM domain containing 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
HIST1H1D histone cluster 1, H1d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOOK1 hook microtubule-tethering protein 1
HOXC10 homeobox C10
HOXC5 homeobox C5
IFI27 interferon, alpha-inducible protein 27
ISG15 ISG15 ubiquitin-like modifier
JUNB jun B proto-oncogene
KIZ kizuna centrosomal protein
KLHL12 kelch-like family member 12
KLHL28 kelch-like family member 28
LOC729164 hCG1732469
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MRPL41 mitochondrial ribosomal protein L41
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NDE1 nudE neurodevelopment protein 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NT5E 5'-nucleotidase, ecto (CD73)
ONECUT2 one cut homeobox 2
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSMR oncostatin M receptor
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIBF1 progesterone immunomodulatory binding factor 1
POM121 POM121 transmembrane nucleoporin
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB3D RAB3D, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS20 regulator of G-protein signaling 20
RLN1 relaxin 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
RUNDC3B RUN domain containing 3B
SCGB2A2 secretoglobin, family 2A, member 2
SIRT2 sirtuin 2
SLC12A8 solute carrier family 12, member 8
SLC41A3 solute carrier family 41, member 3
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SP140L SP140 nuclear body protein-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D17 TBC1 domain family, member 17
TMEM242 transmembrane protein 242
TMEM45A transmembrane protein 45A
TOM1 target of myb1 (chicken)
TRAIP TRAF interacting protein
TRIM21 tripartite motif containing 21
TUBA3C tubulin, alpha 3c
UCN urocortin
USP27X ubiquitin specific peptidase 27, X-linked
VAX2 ventral anterior homeobox 2
WFDC2 WAP four-disulfide core domain 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZIC3 Zic family member 3
ZNF205 zinc finger protein 205
ZNF250 zinc finger protein 250
ZNF571 zinc finger protein 571
ZNF606 zinc finger protein 606
ZNF668 zinc finger protein 668
ZNF750 zinc finger protein 750
ZNF862 zinc finger protein 862