| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/SRC_UP.V1_UP |
| Similar Terms | |
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350 genes differentially expressed following the SRC_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| A1BG-AS1 | A1BG antisense RNA 1 |
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AADAC | arylacetamide deacetylase |
| ABTB1 | ankyrin repeat and BTB (POZ) domain containing 1 |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
| ACY3 | aminoacylase 3 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AIM2 | absent in melanoma 2 |
| AMER1 | APC membrane recruitment protein 1 |
| ANGPTL6 | angiopoietin-like 6 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APC2 | adenomatosis polyposis coli 2 |
| APOA5 | apolipoprotein A-V |
| ARRDC1-AS1 | ARRDC1 antisense RNA 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATOX1 | antioxidant 1 copper chaperone |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCRP3 | breakpoint cluster region pseudogene 3 |
| BMF | Bcl2 modifying factor |
| BRWD1-IT2 | BRWD1 intronic transcript 2 (non-protein coding) |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C2ORF73 | chromosome 2 open reading frame 73 |
| CABP2 | calcium binding protein 2 |
| CALML5 | calmodulin-like 5 |
| CAPS | calcyphosine |
| CCDC23 | coiled-coil domain containing 23 |
| CCDC65 | coiled-coil domain containing 65 |
| CD70 | CD70 molecule |
| CDRT15 | CMT1A duplicated region transcript 15 |
| CEACAM19 | carcinoembryonic antigen-related cell adhesion molecule 19 |
| CFAP45 | cilia and flagella associated protein 45 |
| CFAP46 | cilia and flagella associated protein 46 |
| CFAP74 | cilia and flagella associated protein 74 |
| CHCHD10 | coiled-coil-helix-coiled-coil-helix domain containing 10 |
| CLDN9 | claudin 9 |
| CLIP3 | CAP-GLY domain containing linker protein 3 |
| COL26A1 | collagen, type XXVI, alpha 1 |
| COL4A4 | collagen, type IV, alpha 4 |
| COX4I2 | cytochrome c oxidase subunit IV isoform 2 (lung) |
| CPLX2 | complexin 2 |
| CRTAC1 | cartilage acidic protein 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DLL3 | delta-like 3 (Drosophila) |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUOXA2 | dual oxidase maturation factor 2 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| ESR2 | estrogen receptor 2 (ER beta) |
| ETV7 | ets variant 7 |
| FAM182B | family with sequence similarity 182, member B |
| FBLN2 | fibulin 2 |
| FBXO44 | F-box protein 44 |
| FES | FES proto-oncogene, tyrosine kinase |
| FGF23 | fibroblast growth factor 23 |
| FMN2 | formin 2 |
| FNDC4 | fibronectin type III domain containing 4 |
| FNDC8 | fibronectin type III domain containing 8 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXO4 | forkhead box O4 |
| FUT5 | fucosyltransferase 5 (alpha (1,3) fucosyltransferase) |
| GALK1 | galactokinase 1 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPR15 | G protein-coupled receptor 15 |
| GPR55 | G protein-coupled receptor 55 |
| GPX5 | glutathione peroxidase 5 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HDLBP | high density lipoprotein binding protein |
| HMX1 | H6 family homeobox 1 |
| HPX | hemopexin |
| IBA57-AS1 | IBA57 antisense RNA 1 (head to head) |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IPO5 | importin 5 |
| IRF8 | interferon regulatory factor 8 |
| KCNH3 | potassium channel, voltage gated eag related subfamily H, member 3 |
| KCNQ1DN | KCNQ1 downstream neighbor (non-protein coding) |
| LAMC3 | laminin, gamma 3 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LCE3D | late cornified envelope 3D |
| LEKR1 | leucine, glutamate and lysine rich 1 |
| LELP1 | late cornified envelope-like proline-rich 1 |
| LGI4 | leucine-rich repeat LGI family, member 4 |
| LINC00112 | long intergenic non-protein coding RNA 112 |
| LOC100289650 | uncharacterized LOC100289650 |
| LOC100506127 | putative uncharacterized protein FLJ37770-like |
| LOC254896 | uncharacterized LOC254896 |
| LOC283194 | uncharacterized LOC283194 |
| LOC283475 | uncharacterized LOC283475 |
| LPO | lactoperoxidase |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
| LYZL4 | lysozyme-like 4 |
| MAMDC4 | MAM domain containing 4 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBD3L1 | methyl-CpG binding domain protein 3-like 1 |
| MED10 | mediator complex subunit 10 |
| MGC39584 | uncharacterized LOC441058 |
| MIOX | myo-inositol oxygenase |
| MLXIPL | MLX interacting protein-like |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MORN3 | MORN repeat containing 3 |
| MRPS34 | mitochondrial ribosomal protein S34 |
| MTMR9LP | myotubularin related protein 9-like, pseudogene |
| NAALADL1 | N-acetylated alpha-linked acidic dipeptidase-like 1 |
| NAT8L | N-acetyltransferase 8-like (GCN5-related, putative) |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NKX6-3 | NK6 homeobox 3 |
| NMRK2 | nicotinamide riboside kinase 2 |
| NPC1L1 | NPC1-like 1 |
| NUDT4P1 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1 |
| NYX | nyctalopin |
| OPRL1 | opiate receptor-like 1 |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PCP4 | Purkinje cell protein 4 |
| PDZD7 | PDZ domain containing 7 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| PI16 | peptidase inhibitor 16 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| POU3F2 | POU class 3 homeobox 2 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B |
| PRADC1 | protease-associated domain containing 1 |
| PRPS1L1 | phosphoribosyl pyrophosphate synthetase 1-like 1 |
| PRR3 | proline rich 3 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RFXANK | regulatory factor X-associated ankyrin-containing protein |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCARF2 | scavenger receptor class F, member 2 |
| SEC11C | SEC11 homolog C (S. cerevisiae) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC22A6 | solute carrier family 22 (organic anion transporter), member 6 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC26A1 | solute carrier family 26 (anion exchanger), member 1 |
| SLC35F4 | solute carrier family 35, member F4 |
| SLC4A9 | solute carrier family 4, sodium bicarbonate cotransporter, member 9 |
| SMO | smoothened, frizzled class receptor |
| SMTNL1 | smoothelin-like 1 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRMS | src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites |
| STAB2 | stabilin 2 |
| STAC3 | SH3 and cysteine rich domain 3 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYN1 | synapsin I |
| TAF3 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa |
| TCEAL3 | transcription elongation factor A (SII)-like 3 |
| TECTA | tectorin alpha |
| TFR2 | transferrin receptor 2 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEFF2 | transmembrane protein with EGF-like and two follistatin-like domains 2 |
| TMEM106C | transmembrane protein 106C |
| TMEM11 | transmembrane protein 11 |
| TMEM255B | transmembrane protein 255B |
| TMEM88 | transmembrane protein 88 |
| TMSB4Y | thymosin beta 4, Y-linked |
| TMUB1 | transmembrane and ubiquitin-like domain containing 1 |
| TONSL | tonsoku-like, DNA repair protein |
| TOX3 | TOX high mobility group box family member 3 |
| TRIM15 | tripartite motif containing 15 |
| TTC21A | tetratricopeptide repeat domain 21A |
| TTC25 | tetratricopeptide repeat domain 25 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| VN1R2 | vomeronasal 1 receptor 2 |
| VPS37D | vacuolar protein sorting 37 homolog D (S. cerevisiae) |
| VWA3B | von Willebrand factor A domain containing 3B |
| WTIP | Wilms tumor 1 interacting protein |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTL6A | actin-like 6A |
| ADA | adenosine deaminase |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| ADH4 | alcohol dehydrogenase 4 (class II), pi polypeptide |
| ANO7 | anoctamin 7 |
| APITD1 | apoptosis-inducing, TAF9-like domain 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARRDC3 | arrestin domain containing 3 |
| ARSJ | arylsulfatase family, member J |
| ATAD2 | ATPase family, AAA domain containing 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C11ORF72 | chromosome 11 open reading frame 72 |
| C14ORF142 | chromosome 14 open reading frame 142 |
| C17ORF64 | chromosome 17 open reading frame 64 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C8B | complement component 8, beta polypeptide |
| C9ORF41 | chromosome 9 open reading frame 41 |
| CA7 | carbonic anhydrase VII |
| CAPN12 | calpain 12 |
| CARD16 | caspase recruitment domain family, member 16 |
| CDCA7 | cell division cycle associated 7 |
| CDK11B | cyclin-dependent kinase 11B |
| CENPH | centromere protein H |
| CERKL | ceramide kinase-like |
| CHAC2 | ChaC, cation transport regulator homolog 2 (E. coli) |
| CLCA4 | chloride channel accessory 4 |
| CMTR2 | cap methyltransferase 2 |
| COBL | cordon-bleu WH2 repeat protein |
| COL8A1 | collagen, type VIII, alpha 1 |
| COMMD9 | COMM domain containing 9 |
| COQ4 | coenzyme Q4 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CSAD | cysteine sulfinic acid decarboxylase |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DISC1 | disrupted in schizophrenia 1 |
| DISP2 | dispatched homolog 2 (Drosophila) |
| DPYD | dihydropyrimidine dehydrogenase |
| DTWD1 | DTW domain containing 1 |
| E2F8 | E2F transcription factor 8 |
| EIF3CL | eukaryotic translation initiation factor 3, subunit C-like |
| EMB | embigin |
| EREG | epiregulin |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FAM153A | family with sequence similarity 153, member A |
| FAM173B | family with sequence similarity 173, member B |
| FANCL | Fanconi anemia, complementation group L |
| FRMD4B | FERM domain containing 4B |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GFRA3 | GDNF family receptor alpha 3 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GJB6 | gap junction protein, beta 6, 30kDa |
| GRID1 | glutamate receptor, ionotropic, delta 1 |
| GTF2H2 | general transcription factor IIH, polypeptide 2, 44kDa |
| HOXB2 | homeobox B2 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM10 | interferon induced transmembrane protein 10 |
| IL7R | interleukin 7 receptor |
| IRAK2 | interleukin-1 receptor-associated kinase 2 |
| IRGC | immunity-related GTPase family, cinema |
| IRX5 | iroquois homeobox 5 |
| IVL | involucrin |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0754 | KIAA0754 |
| KIAA1841 | KIAA1841 |
| LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| LIG1 | ligase I, DNA, ATP-dependent |
| LOC285181 | uncharacterized LOC285181 |
| LOC401131 | uncharacterized LOC401131 |
| LOC554174 | uncharacterized LOC554174 |
| LOC644295 | KIAA1143 pseudogene |
| LOC90784 | uncharacterized LOC90784 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MEGF6 | multiple EGF-like-domains 6 |
| MGARP | mitochondria-localized glutamic acid-rich protein |
| MIR17HG | miR-17-92 cluster host gene |
| MMP1 | matrix metallopeptidase 1 |
| MMP10 | matrix metallopeptidase 10 |
| MMP3 | matrix metallopeptidase 3 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MON1A | MON1 secretory trafficking family member A |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 |
| NBEAL1 | neurobeachin-like 1 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NID2 | nidogen 2 (osteonidogen) |
| NLRP8 | NLR family, pyrin domain containing 8 |
| NOL12 | nucleolar protein 12 |
| NPY5R | neuropeptide Y receptor Y5 |
| NRP1 | neuropilin 1 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OTUD6B | OTU domain containing 6B |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PC | pyruvate carboxylase |
| PCDH19 | protocadherin 19 |
| PCDHB4 | protocadherin beta 4 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIK3C2G | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma |
| PKP2 | plakophilin 2 |
| PLAT | plasminogen activator, tissue |
| PLK4 | polo-like kinase 4 |
| POLR1A | polymerase (RNA) I polypeptide A, 194kDa |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPIL1 | peptidylprolyl isomerase (cyclophilin)-like 1 |
| PRR19 | proline rich 19 |
| PRSS33 | protease, serine, 33 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RAB33B | RAB33B, member RAS oncogene family |
| RACGAP1 | Rac GTPase activating protein 1 |
| RAP1A | RAP1A, member of RAS oncogene family |
| RARA | retinoic acid receptor, alpha |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase |
| RNF220 | ring finger protein 220 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| RTN4IP1 | reticulon 4 interacting protein 1 |
| S100A9 | S100 calcium binding protein A9 |
| S1PR3 | sphingosine-1-phosphate receptor 3 |
| SCRN2 | secernin 2 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC7A14 | solute carrier family 7, member 14 |
| SNX32 | sorting nexin 32 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPDYE1 | speedy/RINGO cell cycle regulator family member E1 |
| SPNS3 | spinster homolog 3 (Drosophila) |
| SPRR1B | small proline-rich protein 1B |
| ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STK17B | serine/threonine kinase 17b |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYT1 | synaptotagmin I |
| SYT15 | synaptotagmin XV |
| TGM5 | transglutaminase 5 |
| TMCO2 | transmembrane and coiled-coil domains 2 |
| TMEM14A | transmembrane protein 14A |
| TMOD1 | tropomodulin 1 |
| TREML1 | triggering receptor expressed on myeloid cells-like 1 |
| TRIM73 | tripartite motif containing 73 |
| TTC14 | tetratricopeptide repeat domain 14 |
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| UTS2R | urotensin 2 receptor |
| WASH3P | WAS protein family homolog 3 pseudogene |
| WT1-AS | WT1 antisense RNA |
| ZBED2 | zinc finger, BED-type containing 2 |
| ZNF135 | zinc finger protein 135 |
| ZNF3 | zinc finger protein 3 |
| ZNF436 | zinc finger protein 436 |
| ZNF451 | zinc finger protein 451 |
| ZNF628 | zinc finger protein 628 |
| ZNF721 | zinc finger protein 721 |
| ZNF782 | zinc finger protein 782 |
| ZNF789 | zinc finger protein 789 |
