SREBF1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description sterol regulatory element binding transcription factor 1|This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6720)
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Genes

384 genes differentially expressed following the SREBF1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TMPRSS11F transmembrane protease, serine 11F 3.15328
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 3.15328
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 3.15328
DSG3 desmoglein 3 3.15328
FETUB fetuin B 3.15328
SSTR3 somatostatin receptor 3 3.15328
SFXN3 sideroflexin 3 3.15328
DIRAS3 DIRAS family, GTP-binding RAS-like 3 3.15328
MYOM2 myomesin 2 3.15328
SPINT3 serine peptidase inhibitor, Kunitz type, 3 3.15328
LYNX1 Ly6/neurotoxin 1 3.15328
RIMBP2 RIMS binding protein 2 3.15328
PNMA5 paraneoplastic Ma antigen family member 5 3.15328
SCG2 secretogranin II 3.15328
FBXL8 F-box and leucine-rich repeat protein 8 3.15328
CTRC chymotrypsin C (caldecrin) 3.15328
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 3.15328
CD19 CD19 molecule 3.15328
MUC6 mucin 6, oligomeric mucus/gel-forming 3.15328
CELA3A chymotrypsin-like elastase family, member 3A 3.15328
PCDHB7 protocadherin beta 7 3.15328
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 3.15328
HGD homogentisate 1,2-dioxygenase 3.15328
SFTPB surfactant protein B 3.15328
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.15328
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 3.15328
LEP leptin 3.15328
OTOL1 otolin 1 3.15328
CCDC83 coiled-coil domain containing 83 3.15328
BTBD16 BTB (POZ) domain containing 16 3.15328
PRSS22 protease, serine, 22 3.15328
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 3.15328
OR5A1 olfactory receptor, family 5, subfamily A, member 1 3.15328
GALP galanin-like peptide 3.15328
IRX1 iroquois homeobox 1 3.15328
RTP3 receptor (chemosensory) transporter protein 3 3.15328
NMUR1 neuromedin U receptor 1 3.15328
GMFG glia maturation factor, gamma 3.15328
CD68 CD68 molecule 3.15328
CPB2 carboxypeptidase B2 (plasma) 3.15328
FAM216B family with sequence similarity 216, member B 3.15328
IL2RG interleukin 2 receptor, gamma 3.15328
MRC1 mannose receptor, C type 1 3.15328
CPLX4 complexin 4 3.15328
OR4D9 olfactory receptor, family 4, subfamily D, member 9 3.15328
ATG4A autophagy related 4A, cysteine peptidase 3.15328
LVRN laeverin 3.15328
IRX4 iroquois homeobox 4 3.15328
CIMIP2C ciliary microtubule inner protein 2C 3.15328
ERVW-1 endogenous retrovirus group W, member 1 3.15328
MT4 metallothionein 4 3.15328
PTH1R parathyroid hormone 1 receptor 3.15328
GBP4 guanylate binding protein 4 3.15328
MGAT4D MGAT4 family, member D 3.15328
ELOVL3 ELOVL fatty acid elongase 3 3.15328
SPRR2A small proline-rich protein 2A 3.15328
FOXN4 forkhead box N4 3.15328
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 3.15328
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 3.15328
AJM1 apical junction component 1 homolog 3.15328
RNF227 ring finger protein 227 3.15328
C1ORF232 chromosome 1 open reading frame 230 3.15328
H2BK1 H2B.K variant histone 1 3.15328
H3C13 H3 clustered histone 13 3.15328
RAMACL RNA guanine-7 methyltransferase activating subunit like 3.15328
SPAAR small regulatory polypeptide of amino acid response 3.15328
SMIM35 small integral membrane protein 35 3.15328
GLYATL1B glycine-N-acyltransferase like 1B 3.15328
UBE2L5 ubiquitin conjugating enzyme E2 L5 3.15328
FREY1 Frey regulator of sperm-oocyte fusion 1 3.15328
CFAP157 cilia and flagella associated protein 157 3.15328
MYPN myopalladin 3.15328
HSPA6 heat shock 70kDa protein 6 (HSP70B') 3.15328
SH3TC1 SH3 domain and tetratricopeptide repeats 1 3.15328
GZMM granzyme M (lymphocyte met-ase 1) 3.15328
OVOL3 ovo-like zinc finger 3 3.15328
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.15328
AKR1D1 aldo-keto reductase family 1, member D1 3.15328
EDAR ectodysplasin A receptor 3.15328
CLDN9 claudin 9 3.15328
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 3.15328
PRB3 proline-rich protein BstNI subfamily 3 3.15328
PCDHA7 protocadherin alpha 7 3.15328
GJD2 gap junction protein, delta 2, 36kDa 3.15328
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 3.15328
OR52E6 olfactory receptor, family 52, subfamily E, member 6 3.15328
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 3.15328
BEST3 bestrophin 3 3.15328
LGSN lengsin, lens protein with glutamine synthetase domain 3.15328
GDF6 growth differentiation factor 6 3.15328
IL1R1 interleukin 1 receptor, type I 3.15328
BLNK B-cell linker 3.15328
PGA5 pepsinogen 5, group I (pepsinogen A) 3.15328
SAA4 serum amyloid A4, constitutive 3.15328
CELA2A chymotrypsin-like elastase family, member 2A 3.15328
FPR2 formyl peptide receptor 2 3.15328
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 3.15328
NOBOX NOBOX oogenesis homeobox 3.15328
RGS11 regulator of G-protein signaling 11 3.15328
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 3.15328
NLRC3 NLR family, CARD domain containing 3 3.15328
ANKRD55 ankyrin repeat domain 55 3.15328
EVI2A ecotropic viral integration site 2A 3.15328
KLHL1 kelch-like family member 1 3.15328
RBM25 RNA binding motif protein 25 3.15328
FGR FGR proto-oncogene, Src family tyrosine kinase 3.15328
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 3.15328
PCDHGB4 protocadherin gamma subfamily B, 4 3.15328
PRSS33 protease, serine, 33 3.15328
IL12B interleukin 12B 3.15328
SOSTDC1 sclerostin domain containing 1 3.15328
HSPB9 heat shock protein, alpha-crystallin-related, B9 3.15328
ZMYND10 zinc finger, MYND-type containing 10 3.15328
OR4D6 olfactory receptor, family 4, subfamily D, member 6 3.15328
ANKRD63 ankyrin repeat domain 63 3.15328
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 3.15328
PHOSPHO1 phosphatase, orphan 1 3.15328
HGFAC HGF activator 3.15328
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 3.15328
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 3.15328
WFDC6 WAP four-disulfide core domain 6 3.15328
AGXT2 alanine--glyoxylate aminotransferase 2 3.15328
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 3.15328
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 3.15328
TEKT3 tektin 3 3.15328
OPTC opticin 3.15328
RGCC regulator of cell cycle 3.15328
HRCT1 histidine rich carboxyl terminus 1 3.15328
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 3.15328
CATIP ciliogenesis associated TTC17 interacting protein 3.15328
IL25 interleukin 25 3.15328
SIRPG signal-regulatory protein gamma 3.15328
UTS2B urotensin 2B 3.15328
TRADD TNFRSF1A-associated via death domain 3.15328
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 3.15328
APOC4 apolipoprotein C-IV 3.15328
SST somatostatin 3.15328
MAMLD1 mastermind-like domain containing 1 3.15328
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 3.15328
SERP2 stress-associated endoplasmic reticulum protein family member 2 3.15328
PCDHGA3 protocadherin gamma subfamily A, 3 3.15328
C20ORF144 chromosome 20 open reading frame 144 3.15328
ITGA8 integrin, alpha 8 3.15328
C1ORF105 chromosome 1 open reading frame 105 3.15328
IFITM10 interferon induced transmembrane protein 10 3.15328
ITPKA inositol-trisphosphate 3-kinase A 3.15328
COL22A1 collagen, type XXII, alpha 1 3.15328
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.15328
MAEL maelstrom spermatogenic transposon silencer 3.15328
ADAM20 ADAM metallopeptidase domain 20 3.15328
TMPRSS12 transmembrane (C-terminal) protease, serine 12 3.15328
RBBP8NL RBBP8 N-terminal like 3.15328
TBC1D21 TBC1 domain family, member 21 3.15328
CARD6 caspase recruitment domain family, member 6 3.15328
CETP cholesteryl ester transfer protein, plasma 3.15328
MKRN3 makorin ring finger protein 3 3.15328
TRPM5 transient receptor potential cation channel, subfamily M, member 5 3.15328
AGR3 anterior gradient 3 3.15328
CSF3R colony stimulating factor 3 receptor (granulocyte) 3.15328
UPK1B uroplakin 1B 3.15328
NLRP7 NLR family, pyrin domain containing 7 3.15328
TRPM8 transient receptor potential cation channel, subfamily M, member 8 3.15328
GPR179 G protein-coupled receptor 179 3.15328
NXF2B nuclear RNA export factor 2B 3.15328
NAT10 N-acetyltransferase 10 (GCN5-related) 3.11413
COL6A6 collagen, type VI, alpha 6 3.09166
PARP10 poly (ADP-ribose) polymerase family, member 10 3.09166
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 3.09166
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 2.95477
LY6L lymphocyte antigen 6 family member L 2.95477
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 2.84652
CD37 CD37 molecule 2.82139
TMEM38A transmembrane protein 38A 2.79633
H2AC21 H2A clustered histone 21 2.70629
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 2.70257
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 2.70054
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 2.67755
KHSRP KH-type splicing regulatory protein 2.6749
PLPP2 phospholipid phosphatase 2 2.64401
TMEM192 transmembrane protein 192 2.64124
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 2.6157
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 2.58988
FXYD3 FXYD domain containing ion transport regulator 3 2.58988
KDM5B lysine (K)-specific demethylase 5B 2.56009
RPS3A ribosomal protein S3A 2.56009
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 2.54491
DSEL dermatan sulfate epimerase-like 2.52147
FRMD5 FERM domain containing 5 2.52147
SYCE1L synaptonemal complex central element protein 1-like 2.50838
APMAP adipocyte plasma membrane associated protein 2.49621
PRIMA1 proline rich membrane anchor 1 2.49139
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.47543
YJU2B YJU2 splicing factor homolog B 2.44716
BPIFC BPI fold containing family C 2.43812
MYT1L myelin transcription factor 1-like 2.43812
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.42414
RHOD ras homolog family member D 2.42414
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.41497
ARRDC3 arrestin domain containing 3 2.41176
FANCB Fanconi anemia, complementation group B 2.39846
PNPLA8 patatin-like phospholipase domain containing 8 2.38502
USP8 ubiquitin specific peptidase 8 2.37758
INO80C INO80 complex subunit C 2.37211
LIMS1 LIM and senescent cell antigen-like domains 1 2.36163
CCSER1 coiled-coil serine-rich protein 1 2.36163
PKN3 protein kinase N3 2.36163
TMEM39B transmembrane protein 39B 2.36163
CCDC148 coiled-coil domain containing 148 2.36163
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.35901
POLR1B polymerase (RNA) I polypeptide B, 128kDa 2.34881
SYT7 synaptotagmin VII 2.33812
BAMBI BMP and activin membrane-bound inhibitor 2.33202
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.32221
AGRN agrin 2.30864
ZFP1 ZFP1 zinc finger protein 2.29906
PLAAT4 phospholipase A and acyltransferase 4 2.29036
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 2.29036
PLA2G4B phospholipase A2, group IVB (cytosolic) 2.29036
PTPRB protein tyrosine phosphatase, receptor type, B 2.29036
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.29036
H3C14 H3 clustered histone 14 2.29036
C1ORF122 chromosome 1 open reading frame 122 2.28863
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 2.28571
METTL13 methyltransferase like 13 2.28539
ZNF561 zinc finger protein 561 2.28229
FSD1 fibronectin type III and SPRY domain containing 1 2.26195
PIERCE1 piercer of microtubule wall 1 2.25877
STXBP4 syntaxin binding protein 4 2.25755
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor 2.24847
RGL3 ral guanine nucleotide dissociation stimulator-like 3 2.24191
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 2.23587
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 2.23259
QTRT1 queuine tRNA-ribosyltransferase 1 2.22823
IL4R interleukin 4 receptor 2.21541
NPW neuropeptide W 2.21226
PDE4A phosphodiesterase 4A, cAMP-specific 2.19164
LIPG lipase, endothelial 2.18399
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 2.18365
CERS1 ceramide synthase 1 2.18349
CABLES2 Cdk5 and Abl enzyme substrate 2 2.18116
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.17708
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 2.17676
DDIAS DNA damage-induced apoptosis suppressor 2.16103
KIZ kizuna centrosomal protein 2.13005
TMEM237 transmembrane protein 237 2.13005
NMI N-myc (and STAT) interactor 2.12686
RAVER2 ribonucleoprotein, PTB-binding 2 2.12506
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) 2.11931
PYROXD2 pyridine nucleotide-disulphide oxidoreductase domain 2 2.11903
PHLDB3 pleckstrin homology-like domain, family B, member 3 2.10903
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.10237
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 2.10237
ZNF454 zinc finger protein 454 2.07129
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 2.06124
ZNF721 zinc finger protein 721 2.04825
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 2.04725
B3GAT3 beta-1,3-glucuronyltransferase 3 2.04666
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.03244
CTCF CCCTC-binding factor (zinc finger protein) 2.03024
SARM1 sterile alpha and TIR motif containing 1 2.02372
GRHPR glyoxylate reductase/hydroxypyruvate reductase 2.02372
KIDINS220 kinase D-interacting substrate, 220kDa 2.02132

decreased expression

Symbol Name Standardized Value
TMEM81 transmembrane protein 81 -3.15328
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 -3.15328
ZC2HC1A zinc finger, C2HC-type containing 1A -3.15328
METTL24 methyltransferase like 24 -3.15328
DNAH11 dynein, axonemal, heavy chain 11 -3.15328
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 -3.15328
CCDC183 coiled-coil domain containing 183 -3.15328
INSL3 insulin-like 3 (Leydig cell) -3.15328
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -3.15328
POLH polymerase (DNA directed), eta -3.06117
FASTKD3 FAST kinase domains 3 -3.02687
FAM86B2 family with sequence similarity 86, member B2 -2.99914
FXYD2 FXYD domain containing ion transport regulator 2 -2.98964
TMEM45B transmembrane protein 45B -2.98964
TMEM171 transmembrane protein 171 -2.98964
TMEM86A transmembrane protein 86A -2.98964
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 -2.98964
RLN1 relaxin 1 -2.98964
NUTM2A NUT family member 2A -2.98964
HCRTR2 hypocretin (orexin) receptor 2 -2.98964
ADAD2 adenosine deaminase domain containing 2 -2.98964
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) -2.98964
LTB lymphotoxin beta (TNF superfamily, member 3) -2.98964
CCR9 chemokine (C-C motif) receptor 9 -2.98964
FAM186B family with sequence similarity 186, member B -2.98964
ACTA1 actin, alpha 1, skeletal muscle -2.98964
OR8D4 olfactory receptor, family 8, subfamily D, member 4 -2.98964
AMBP alpha-1-microglobulin/bikunin precursor -2.98964
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 -2.98964
LOX lysyl oxidase -2.98964
NDRG1 N-myc downstream regulated 1 -2.98964
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -2.98964
NOTO notochord homeobox -2.98964
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -2.98964
DUSP15 dual specificity phosphatase 15 -2.98964
TEKTL1 tektin like 1 -2.98964
NTSR1 neurotensin receptor 1 (high affinity) -2.98964
HCRT hypocretin (orexin) neuropeptide precursor -2.98964
EBF2 early B-cell factor 2 -2.98964
ORM2 orosomucoid 2 -2.98964
DAW1 dynein assembly factor with WDR repeat domains 1 -2.98964
CTXN2 cortexin 2 -2.98964
SOD3 superoxide dismutase 3, extracellular -2.98964
PAPOLB poly(A) polymerase beta (testis specific) -2.98964
GP1BB glycoprotein Ib (platelet), beta polypeptide -2.98964
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -2.98964
STAB2 stabilin 2 -2.98964
ERCC5 excision repair cross-complementation group 5 -2.98964
CLIC5 chloride intracellular channel 5 -2.98964
FASTK Fas-activated serine/threonine kinase -2.86825
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.84414
CIAO1 cytosolic iron-sulfur assembly component 1 -2.82492
GIPC2 GIPC PDZ domain containing family, member 2 -2.79633
HELZ helicase with zinc finger -2.76635
UBE2W ubiquitin-conjugating enzyme E2W (putative) -2.72043
SH3D19 SH3 domain containing 19 -2.71513
CPEB2 cytoplasmic polyadenylation element binding protein 2 -2.64948
VWCE von Willebrand factor C and EGF domains -2.64863
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C -2.64401
AKR1C1 aldo-keto reductase family 1, member C1 -2.62178
JADE1 jade family PHD finger 1 -2.6152
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -2.53861
CTTNBP2 cortactin binding protein 2 -2.5261
MAP2K6 mitogen-activated protein kinase kinase 6 -2.50838
TIGD6 tigger transposable element derived 6 -2.50838
R3HCC1L R3H domain and coiled-coil containing 1-like -2.50224
TSPAN33 tetraspanin 33 -2.49967
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -2.49651
RIOX1 ribosomal oxygenase 1 -2.47543
OTOG otogelin -2.47543
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 -2.47543
SMYD5 SMYD family member 5 -2.42984
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 -2.41176
TSLIG1 tRNA splicing ligase complex subunit 1 -2.41095
ACSL6 acyl-CoA synthetase long-chain family member 6 -2.39846
SYNPO synaptopodin -2.39846
MYO7A myosin VIIA -2.36163
HSPA9 heat shock 70kDa protein 9 (mortalin) -2.36163
SAXO2 stabilizer of axonemal microtubules 2 -2.36163
FAM178B family with sequence similarity 178, member B -2.36163
C19ORF81 chromosome 19 open reading frame 81 -2.36163
CFAP61 cilia and flagella associated protein 61 -2.36163
TMEM200C transmembrane protein 200C -2.34881
SPOP speckle-type POZ protein -2.33783
RSU1 Ras suppressor protein 1 -2.31242
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -2.30808
C19ORF53 chromosome 19 open reading frame 53 -2.29315
ZNF624 zinc finger protein 624 -2.29097
SH3GL2 SH3-domain GRB2-like 2 -2.28863
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 -2.28229
UST uronyl-2-sulfotransferase -2.27434
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -2.25978
HDAC2 histone deacetylase 2 -2.25877
F13A1 coagulation factor XIII, A1 polypeptide -2.1892
ACSL4 acyl-CoA synthetase long-chain family member 4 -2.18821
APLP2 amyloid beta (A4) precursor-like protein 2 -2.17708
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.17286
MRM3 mitochondrial rRNA methyltransferase 3 -2.16103
KIAA1549L KIAA1549-like -2.13596
C6ORF163 chromosome 6 open reading frame 163 -2.13005
BEAN1 brain expressed, associated with NEDD4, 1 -2.13005
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -2.13005
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -2.13005
TSLP thymic stromal lymphopoietin -2.13005
HACL1 2-hydroxyacyl-CoA lyase 1 -2.13005
RAB6A RAB6A, member RAS oncogene family -2.12506
MISO1 mitochondrial inner membrane subdomain organizer 1 -2.11307
CSRP1 cysteine and glycine-rich protein 1 -2.10811
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -2.10811
DEPDC1 DEP domain containing 1 -2.10811
FGF11 fibroblast growth factor 11 -2.0937
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.0918
NUDCD1 NudC domain containing 1 -2.06136
GULP1 GULP, engulfment adaptor PTB domain containing 1 -2.06131
C1ORF226 chromosome 1 open reading frame 226 -2.04666
MARF1 meiosis regulator and mRNA stability factor 1 -2.03509
WDR82 WD repeat domain 82 -2.03396
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I -2.02423
SUMF2 sulfatase modifying factor 2 -2.02132
TRAPPC8 trafficking protein particle complex 8 -2.02132
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -2.00827
CCDC59 coiled-coil domain containing 59 -2.00375