SREBF2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description sterol regulatory element binding transcription factor 2|This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 6721)
External Link https://ncbi.nlm.nih.gov/gene/6721
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Genes

499 genes differentially expressed following the SREBF2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPB1 heat shock 27kDa protein 1 0.0155883
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.0122512
GNAS GNAS complex locus 0.0115503
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0101376
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0098814
CA12 carbonic anhydrase XII 0.0098345
SIK1 salt-inducible kinase 1 0.00978375
KRT15 keratin 15, type I 0.00917191
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00907389
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00891647
TFPI2 tissue factor pathway inhibitor 2 0.00885839
E2F2 E2F transcription factor 2 0.00873609
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00844974
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00829585
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00829406
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.008258
HSPA1A heat shock 70kDa protein 1A 0.0082551
VEGFA vascular endothelial growth factor A 0.00823151
MYOF myoferlin 0.00809871
FN1 fibronectin 1 0.00792862
SIRT3 sirtuin 3 0.00788805
STC2 stanniocalcin 2 0.00784964
MYBPC1 myosin binding protein C, slow type 0.00779782
PITX3 paired-like homeodomain 3 0.0075326
CD9 CD9 molecule 0.00747874
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00743692
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00725705
PNMA2 paraneoplastic Ma antigen 2 0.00715961
NRCAM neuronal cell adhesion molecule 0.0071524
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.00713004
ZFAND5 zinc finger, AN1-type domain 5 0.00711764
HTRA1 HtrA serine peptidase 1 0.00711179
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00710574
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00701943
RGS4 regulator of G-protein signaling 4 0.00697585
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.00695549
UPK1B uroplakin 1B 0.00693907
PLBD1 phospholipase B domain containing 1 0.00692614
KRT5 keratin 5, type II 0.0069196
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00690432
TGM2 transglutaminase 2 0.00684932
EMX2 empty spiracles homeobox 2 0.00684822
ANXA1 annexin A1 0.00683849
FOLR1 folate receptor 1 (adult) 0.00682454
ECM1 extracellular matrix protein 1 0.00681057
KRT14 keratin 14, type I 0.00674526
IGSF1 immunoglobulin superfamily, member 1 0.00669305
CAPN3 calpain 3, (p94) 0.00664561
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00663631
PDHX pyruvate dehydrogenase complex, component X 0.00661727
SCPEP1 serine carboxypeptidase 1 0.00660673
KDM5A lysine (K)-specific demethylase 5A 0.00656172
KRT7 keratin 7, type II 0.00655533
WARS1 tryptophanyl-tRNA synthetase 1 0.00654663
OXTR oxytocin receptor 0.00650242
TNNT1 troponin T type 1 (skeletal, slow) 0.00649575
KRT17 keratin 17, type I 0.00648016
DLK1 delta-like 1 homolog (Drosophila) 0.00646487
SPRR3 small proline-rich protein 3 0.0064585
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00637908
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00631191
TCTA T-cell leukemia translocation altered 0.00630714
PRSS21 protease, serine, 21 (testisin) 0.00629842
CTSB cathepsin B 0.00627286
PADI2 peptidyl arginine deiminase, type II 0.00625909
IFRD1 interferon-related developmental regulator 1 0.00624699
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00623485
JUNB jun B proto-oncogene 0.00620197
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.00618753
TNNC1 troponin C type 1 (slow) 0.00617345
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00617295
MAGEA3 melanoma antigen family A3 0.00615445
PKM pyruvate kinase, muscle 0.00614951
PDE8B phosphodiesterase 8B 0.00613713
SLPI secretory leukocyte peptidase inhibitor 0.00612024
P3H2 prolyl 3-hydroxylase 2 0.00610474
TNS3 tensin 3 0.00609274
FHOD3 formin homology 2 domain containing 3 0.00603103
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00601084
LBH limb bud and heart development 0.00599826
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.00598649
RHOBTB3 Rho-related BTB domain containing 3 0.00595218
ZNF395 zinc finger protein 395 0.00593507
LARP4B La ribonucleoprotein domain family, member 4B 0.00593319
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00592981
DDIT3 DNA-damage-inducible transcript 3 0.00588801
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00585402
NCOA3 nuclear receptor coactivator 3 0.00584684
MB myoglobin 0.0058251
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00581829
AKR1C2 aldo-keto reductase family 1, member C2 0.00581133
RFTN1 raftlin, lipid raft linker 1 0.0057605
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00573283
FXYD3 FXYD domain containing ion transport regulator 3 0.00571612
MET MET proto-oncogene, receptor tyrosine kinase 0.00570423
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0057024
HK2 hexokinase 2 0.00570229
LTF lactotransferrin 0.00566584
FABP7 fatty acid binding protein 7, brain 0.00565968
TACSTD2 tumor-associated calcium signal transducer 2 0.00563088
PRAME preferentially expressed antigen in melanoma 0.00560649
TRIM44 tripartite motif containing 44 0.00557499
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00555254
C10ORF10 chromosome 10 open reading frame 10 0.00547124
TPM4 tropomyosin 4 0.00543242
KLF9 Kruppel-like factor 9 0.00541443
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00541216
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00540873
TRIM29 tripartite motif containing 29 0.00540846
PFKP phosphofructokinase, platelet 0.0054019
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00539906
MBD2 methyl-CpG binding domain protein 2 0.00538894
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00536497
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00536475
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.00534614
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00534068
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00531429
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00531262
CCNA1 cyclin A1 0.00531157
TM4SF1 transmembrane 4 L six family member 1 0.00530682
ZBED2 zinc finger, BED-type containing 2 0.00530274
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.00527733
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00527601
COL6A3 collagen, type VI, alpha 3 0.00526745
KRT6A keratin 6A, type II 0.00526015
WNK1 WNK lysine deficient protein kinase 1 0.00525065
PFN2 profilin 2 0.00524671
KRT13 keratin 13, type I 0.00523828
ADAM10 ADAM metallopeptidase domain 10 0.00522317
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00522022
ASCL1 achaete-scute family bHLH transcription factor 1 0.00521088
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.00520555
TRIM22 tripartite motif containing 22 0.00519513
LTBP1 latent transforming growth factor beta binding protein 1 0.00518229
PSG5 pregnancy specific beta-1-glycoprotein 5 0.00518196
GBP2 guanylate binding protein 2, interferon-inducible 0.00517716
S100P S100 calcium binding protein P 0.0051703
HK1 hexokinase 1 0.00516229
CPM carboxypeptidase M 0.00515725
YME1L1 YME1-like 1 ATPase 0.00514928
CEMIP cell migration inducing protein, hyaluronan binding 0.00510154
PRKCI protein kinase C, iota 0.00510002
CRH corticotropin releasing hormone 0.00509181
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00509134
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.00508796
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00508643
CDC123 cell division cycle 123 0.00508457
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00508228
ZNF185 zinc finger protein 185 (LIM domain) 0.00507512
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00507374
SLN sarcolipin 0.00506954
PARD3 par-3 family cell polarity regulator 0.00505904
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00504676
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00502873
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.00502126
MAST4 microtubule associated serine/threonine kinase family member 4 0.00501685
CRCT1 cysteine-rich C-terminal 1 0.00500738
CDH18 cadherin 18, type 2 0.00500465
PLCB4 phospholipase C, beta 4 0.00495254
OSBPL9 oxysterol binding protein-like 9 0.00495093
FTH1 ferritin, heavy polypeptide 1 0.00494308
ITPKC inositol-trisphosphate 3-kinase C 0.00491887
DCT dopachrome tautomerase 0.0049149
KRT23 keratin 23, type I 0.00490724
DYNLL1 dynein, light chain, LC8-type 1 0.00490135
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00489405
PCSK2 proprotein convertase subtilisin/kexin type 2 0.00487255
MMP7 matrix metallopeptidase 7 0.00484755
SCEL sciellin 0.00483574
ZBTB38 zinc finger and BTB domain containing 38 0.00482752
LIMS1 LIM and senescent cell antigen-like domains 1 0.00480813
RALBP1 ralA binding protein 1 0.00479889
CAPRIN2 caprin family member 2 0.00478714
NEFH neurofilament, heavy polypeptide 0.00477874
PEG10 paternally expressed 10 0.00476792
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00476051
COCH cochlin 0.00475851
BHMT betaine--homocysteine S-methyltransferase 0.00475048
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00475021
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.00474026
NPC2 Niemann-Pick disease, type C2 0.00471972
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00471858
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00471598
OGFRL1 opioid growth factor receptor-like 1 0.00471121
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.0046953
MYO7A myosin VIIA 0.00469432
CALB1 calbindin 1, 28kDa 0.00467604
ELF5 E74-like factor 5 (ets domain transcription factor) 0.0046672
PRKCA protein kinase C, alpha 0.00465813
IL1B interleukin 1, beta 0.00465396
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00464834
PGBD5 piggyBac transposable element derived 5 0.0046339
RRAS related RAS viral (r-ras) oncogene homolog 0.004625
CTSH cathepsin H 0.00461052
LTA4H leukotriene A4 hydrolase 0.00460966
ALOX15B arachidonate 15-lipoxygenase, type B 0.004601
SYNGR3 synaptogyrin 3 0.00459879
RABGAP1 RAB GTPase activating protein 1 0.00459561
EPX eosinophil peroxidase 0.00459495
GDI2 GDP dissociation inhibitor 2 0.00459293
CKM creatine kinase, muscle 0.00458955
IGFBP6 insulin-like growth factor binding protein 6 0.00458095
PLD3 phospholipase D family, member 3 0.00457455
NOX1 NADPH oxidase 1 0.00457406
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00456419
CD59 CD59 molecule, complement regulatory protein 0.00454641
EIF5 eukaryotic translation initiation factor 5 0.00454123
LGALS3 lectin, galactoside-binding, soluble, 3 0.00453309
PKP1 plakophilin 1 0.00453286
CHMP4A charged multivesicular body protein 4A 0.00452659
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.00450121
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00449781
MAP1A microtubule-associated protein 1A 0.00448765
C1S complement component 1, s subcomponent 0.00448234
C3 complement component 3 0.0044802
TBX2 T-box 2 0.00447513
PORCN porcupine homolog (Drosophila) 0.00447199
PTPRK protein tyrosine phosphatase, receptor type, K 0.00446829
CTSE cathepsin E 0.00446005
SLC16A4 solute carrier family 16, member 4 0.00445325
RAP2A RAP2A, member of RAS oncogene family 0.00443889
F3 coagulation factor III (thromboplastin, tissue factor) 0.00442771
SCGB2A1 secretoglobin, family 2A, member 1 0.0044111
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.0044091
TRIM24 tripartite motif containing 24 0.00440846
ZNF580 zinc finger protein 580 0.00440759
TRIP6 thyroid hormone receptor interactor 6 0.00440711
LRRC17 leucine rich repeat containing 17 0.00439701
PSG4 pregnancy specific beta-1-glycoprotein 4 0.00436917
MIR22HG MIR22 host gene 0.00435871
FNDC3B fibronectin type III domain containing 3B 0.00435643
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00435601
ANGPT1 angiopoietin 1 0.00435465
CNTNAP1 contactin associated protein 1 0.00434098
IGFBP5 insulin-like growth factor binding protein 5 0.00433947
BTF3P11 basic transcription factor 3 pseudogene 11 0.00433613
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.00433443
CDA cytidine deaminase 0.00433346
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00433152
TCEAL4 transcription elongation factor A (SII)-like 4 0.00432997
CNN3 calponin 3, acidic 0.00432759
GJA1 gap junction protein, alpha 1, 43kDa 0.00432603
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00432487
CYB561 cytochrome b561 0.00432359
S100A11 S100 calcium binding protein A11 0.00432144
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.00431317
NEBL nebulette 0.00431146
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.00430111
CKAP4 cytoskeleton-associated protein 4 0.00430013

decreased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II -0.0146586
GREM1 gremlin 1, DAN family BMP antagonist -0.0143749
HOXC6 homeobox C6 -0.0122126
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0121588
PROM1 prominin 1 -0.0121509
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0120663
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0118598
HBB hemoglobin, beta -0.0112946
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0106556
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0102969
CXCL12 chemokine (C-X-C motif) ligand 12 -0.0102718
BMP4 bone morphogenetic protein 4 -0.010098
MFAP5 microfibrillar associated protein 5 -0.0100909
ARHGAP29 Rho GTPase activating protein 29 -0.0100135
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00974752
CPVL carboxypeptidase, vitellogenic-like -0.00968063
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00959447
PRDX2 peroxiredoxin 2 -0.00930134
TMSB15A thymosin beta 15a -0.00929269
FABP4 fatty acid binding protein 4, adipocyte -0.0087817
COL10A1 collagen, type X, alpha 1 -0.00858522
LYZ lysozyme -0.00856744
MMP3 matrix metallopeptidase 3 -0.00845189
AMDHD2 amidohydrolase domain containing 2 -0.00834482
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00831564
TOX3 TOX high mobility group box family member 3 -0.00825365
CD99 CD99 molecule -0.00796998
TNC tenascin C -0.00795997
CCL8 chemokine (C-C motif) ligand 8 -0.0078673
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00779411
CFD complement factor D (adipsin) -0.00763895
EIF5A eukaryotic translation initiation factor 5A -0.0075978
PDLIM3 PDZ and LIM domain 3 -0.0075499
SPARCL1 SPARC-like 1 (hevin) -0.00742686
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.0073781
CCL19 chemokine (C-C motif) ligand 19 -0.00733725
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00732897
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0072685
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00726519
ZBTB18 zinc finger and BTB domain containing 18 -0.00721635
SPON1 spondin 1, extracellular matrix protein -0.007177
DPT dermatopontin -0.00717018
PDGFRL platelet-derived growth factor receptor-like -0.00714802
ASPN asporin -0.00711816
ALDOB aldolase B, fructose-bisphosphate -0.00710316
REEP1 receptor accessory protein 1 -0.00703511
GAS1 growth arrest-specific 1 -0.00702543
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00702278
PLN phospholamban -0.00698862
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00697504
STK10 serine/threonine kinase 10 -0.00687083
CPE carboxypeptidase E -0.00686038
GUSBP3 glucuronidase, beta pseudogene 3 -0.00681187
CCL13 chemokine (C-C motif) ligand 13 -0.00676701
CCL21 chemokine (C-C motif) ligand 21 -0.00673739
GOLM1 golgi membrane protein 1 -0.00672803
COL14A1 collagen, type XIV, alpha 1 -0.0067112
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00669855
FCGBP Fc fragment of IgG binding protein -0.00665368
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -0.0065726
CRIP1 cysteine-rich protein 1 (intestinal) -0.00652334
COL6A2 collagen, type VI, alpha 2 -0.00644789
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00643046
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00643001
FGF13 fibroblast growth factor 13 -0.00640879
CD36 CD36 molecule (thrombospondin receptor) -0.00639419
CLEC2B C-type lectin domain family 2, member B -0.00637547
FXYD6 FXYD domain containing ion transport regulator 6 -0.00636028
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.00633103
MYO1D myosin ID -0.00630422
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00628871
CFH complement factor H -0.00623865
CRIP2 cysteine-rich protein 2 -0.00623463
C7 complement component 7 -0.0062243
HOXA10 homeobox A10 -0.00622137
HAT1 histone acetyltransferase 1 -0.00620636
IRF7 interferon regulatory factor 7 -0.00618397
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00616527
GPR183 G protein-coupled receptor 183 -0.00615317
CDCA4 cell division cycle associated 4 -0.00609434
CHN2 chimerin 2 -0.00608443
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00607095
NRN1 neuritin 1 -0.00606677
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00604944
NELL2 NEL-like 2 (chicken) -0.00603521
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00599845
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00593649
CLU clusterin -0.00592529
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00587152
CLGN calmegin -0.00586836
SLC44A4 solute carrier family 44, member 4 -0.00586629
BCHE butyrylcholinesterase -0.00584797
LTBP2 latent transforming growth factor beta binding protein 2 -0.00583247
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) -0.00580134
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.00579044
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00579042
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00577611
SPON2 spondin 2, extracellular matrix protein -0.00573341
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.00569359
MEOX1 mesenchyme homeobox 1 -0.0056418
MYL9 myosin, light chain 9, regulatory -0.00563929
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 -0.0056343
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00563203
TMEM204 transmembrane protein 204 -0.00562562
CADPS2 Ca++-dependent secretion activator 2 -0.00562554
EPPK1 epiplakin 1 -0.00559819
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00556804
RAB25 RAB25, member RAS oncogene family -0.0055585
GPM6A glycoprotein M6A -0.00552689
REG3A regenerating islet-derived 3 alpha -0.00552236
MTUS1 microtubule associated tumor suppressor 1 -0.00551004
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00549883
CKS1B CDC28 protein kinase regulatory subunit 1B -0.00547582
SDC2 syndecan 2 -0.00545046
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00544549
TAGLN transgelin -0.00540892
PIP prolactin-induced protein -0.00540564
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00539357
HEPH hephaestin -0.00539306
FBLN2 fibulin 2 -0.00537224
GAL galanin/GMAP prepropeptide -0.00535691
ASPH aspartate beta-hydroxylase -0.00535328
S100A4 S100 calcium binding protein A4 -0.00535097
NLGN4X neuroligin 4, X-linked -0.00534139
PHF20 PHD finger protein 20 -0.00533183
DCK deoxycytidine kinase -0.00532382
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00532199
GSTM3 glutathione S-transferase mu 3 (brain) -0.00530385
MMP15 matrix metallopeptidase 15 (membrane-inserted) -0.00529508
SEPTIN10 septin 10 -0.0052824
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00527247
ELP5 elongator acetyltransferase complex subunit 5 -0.00526465
PDE2A phosphodiesterase 2A, cGMP-stimulated -0.00524896
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00524029
PALLD palladin, cytoskeletal associated protein -0.00523576
RAB38 RAB38, member RAS oncogene family -0.00523561
CTBP1 C-terminal binding protein 1 -0.00521384
TFF3 trefoil factor 3 (intestinal) -0.00521032
REG1A regenerating islet-derived 1 alpha -0.00520433
MAP7 microtubule-associated protein 7 -0.00519941
COMP cartilage oligomeric matrix protein -0.00518936
DUSP5 dual specificity phosphatase 5 -0.00517451
CTBP2 C-terminal binding protein 2 -0.00514663
CCNB1 cyclin B1 -0.00513136
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00512923
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00512779
CD320 CD320 molecule -0.00510712
CDHR5 cadherin-related family member 5 -0.00510474
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00509353
NPM3 nucleophosmin/nucleoplasmin 3 -0.0050874
SKAP2 src kinase associated phosphoprotein 2 -0.00508517
STK17A serine/threonine kinase 17a -0.00508388
TSPAN13 tetraspanin 13 -0.00508018
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -0.00507476
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00506922
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00505281
PLSCR4 phospholipid scramblase 4 -0.00504545
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00503994
FGFR2 fibroblast growth factor receptor 2 -0.00503586
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -0.0050315
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00501466
RNF144A ring finger protein 144A -0.00501148
DCXR dicarbonyl/L-xylulose reductase -0.00500483
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00499896
CXCL6 chemokine (C-X-C motif) ligand 6 -0.00499632
PDLIM2 PDZ and LIM domain 2 (mystique) -0.00496519
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00496255
CD302 CD302 molecule -0.00495606
SFRP1 secreted frizzled-related protein 1 -0.00495283
ZNF652 zinc finger protein 652 -0.00494613
POGLUT2 protein O-glucosyltransferase 2 -0.0049387
HOXB6 homeobox B6 -0.00493236
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) -0.00493124
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.00492855
LINC00623 long intergenic non-protein coding RNA 623 -0.00491603
EFNA4 ephrin-A4 -0.00490001
SCAND1 SCAN domain containing 1 -0.00489448
FRZB frizzled-related protein -0.00489131
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00488789
SC5D sterol-C5-desaturase -0.00488427
MMP1 matrix metallopeptidase 1 -0.00484629
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00482741
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00481846
ISG15 ISG15 ubiquitin-like modifier -0.00480073
SHMT1 serine hydroxymethyltransferase 1 (soluble) -0.00479492
CALD1 caldesmon 1 -0.00478841
REG1B regenerating islet-derived 1 beta -0.00477762
ECI2 enoyl-CoA delta isomerase 2 -0.00477471
NXN nucleoredoxin -0.00476978
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.0047679
CCL11 chemokine (C-C motif) ligand 11 -0.00476472
MGP matrix Gla protein -0.00474866
INSR insulin receptor -0.00474791
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.00474724
C1ORF115 chromosome 1 open reading frame 115 -0.00474665
GAMT guanidinoacetate N-methyltransferase -0.00474321
TMEM255A transmembrane protein 255A -0.00472353
FAM46C family with sequence similarity 46, member C -0.00472225
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00472162
SDC1 syndecan 1 -0.00471808
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.0047129
NR3C2 nuclear receptor subfamily 3, group C, member 2 -0.00470542
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00469521
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0046869
KRT20 keratin 20, type I -0.00468465
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00468125
ZFPM2 zinc finger protein, FOG family member 2 -0.00467729
ETNK1 ethanolamine kinase 1 -0.00467436
NPTX2 neuronal pentraxin II -0.00467389
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00466465
CEP43 centrosomal protein 43 -0.0046606
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.0046562
THAP7 THAP domain containing 7 -0.00465235
CLEC3B C-type lectin domain family 3, member B -0.00462989
TMX1 thioredoxin-related transmembrane protein 1 -0.00461979
CPOX coproporphyrinogen oxidase -0.00460552
PRPF4 pre-mRNA processing factor 4 -0.00460238
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00460135
DUSP6 dual specificity phosphatase 6 -0.00459779
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00459587
TWIST1 twist family bHLH transcription factor 1 -0.00459361
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -0.00459188
EVA1B eva-1 homolog B (C. elegans) -0.00459052
EMILIN1 elastin microfibril interfacer 1 -0.00458872
EMP3 epithelial membrane protein 3 -0.00458813
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00458551
CISH cytokine inducible SH2-containing protein -0.00458106
MFSD10 major facilitator superfamily domain containing 10 -0.00458064
MAB21L2 mab-21-like 2 (C. elegans) -0.00457093
FBLN5 fibulin 5 -0.00456709
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.0045625
MCAM melanoma cell adhesion molecule -0.00455659
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -0.00455619
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00455584
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -0.00454517
DPYSL3 dihydropyrimidinase-like 3 -0.00454137
KLHL23 kelch-like family member 23 -0.00453984
DEK DEK proto-oncogene -0.0045352
CD209 CD209 molecule -0.00452731
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00451759
CXADR coxsackie virus and adenovirus receptor -0.00451635
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00450428
SMTN smoothelin -0.00449973
ITM2C integral membrane protein 2C -0.00449048
CYTIP cytohesin 1 interacting protein -0.00449015
NUP43 nucleoporin 43kDa -0.00448869
CYBRD1 cytochrome b reductase 1 -0.00448132
CLCA1 chloride channel accessory 1 -0.00448067
DAXX death-domain associated protein -0.0044641
NMU neuromedin U -0.00445394