SRF Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description serum response factor (c-fos serum response element-binding transcription factor)|This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 6722)
External Link https://ncbi.nlm.nih.gov/gene/6722
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Genes

500 genes differentially expressed following the SRF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 0.0124079
IFI27 interferon, alpha-inducible protein 27 0.0121883
KRT7 keratin 7, type II 0.0121545
HSPA1A heat shock 70kDa protein 1A 0.0119426
AMIGO2 adhesion molecule with Ig-like domain 2 0.0116761
MYRF myelin regulatory factor 0.0104484
LOXL2 lysyl oxidase-like 2 0.0103826
SLC38A1 solute carrier family 38, member 1 0.0103184
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0102297
PLAAT3 phospholipase A and acyltransferase 3 0.0100982
MFSD10 major facilitator superfamily domain containing 10 0.00981791
FNDC3B fibronectin type III domain containing 3B 0.00930236
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0092698
PLAU plasminogen activator, urokinase 0.00922561
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00912606
GJA1 gap junction protein, alpha 1, 43kDa 0.00912321
BIK BCL2-interacting killer (apoptosis-inducing) 0.00901634
TNS3 tensin 3 0.00890676
XIC X chromosome inactivation center 0.0088308
PEG10 paternally expressed 10 0.0087343
MGLL monoglyceride lipase 0.00867143
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00855848
MXRA5 matrix-remodelling associated 5 0.00841204
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00840904
TPD52 tumor protein D52 0.00835168
MLPH melanophilin 0.00831912
KLK10 kallikrein-related peptidase 10 0.00825249
ISG15 ISG15 ubiquitin-like modifier 0.00783213
TFPI2 tissue factor pathway inhibitor 2 0.00777978
IFI6 interferon, alpha-inducible protein 6 0.0077263
COL9A2 collagen, type IX, alpha 2 0.00770572
KLK11 kallikrein-related peptidase 11 0.00767698
IRS2 insulin receptor substrate 2 0.00766948
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00760616
INHBB inhibin, beta B 0.00758311
OLFML2A olfactomedin-like 2A 0.00755828
COL6A2 collagen, type VI, alpha 2 0.0075417
MVP major vault protein 0.00739417
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.00736426
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00735882
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00732987
SCGB1D2 secretoglobin, family 1D, member 2 0.00728308
DUSP5 dual specificity phosphatase 5 0.00721868
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00721082
IFI44L interferon-induced protein 44-like 0.00718971
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00718891
MT2A metallothionein 2A 0.0071505
MYOF myoferlin 0.00714993
EPHB2 EPH receptor B2 0.00709309
MX2 MX dynamin-like GTPase 2 0.0070617
TSPAN15 tetraspanin 15 0.00704022
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.00698823
BIRC3 baculoviral IAP repeat containing 3 0.00697312
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00692968
TICAM1 toll-like receptor adaptor molecule 1 0.00692263
KRT81 keratin 81, type II 0.00686271
PFKP phosphofructokinase, platelet 0.00685634
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00682547
IRF7 interferon regulatory factor 7 0.00680517
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 0.00675771
PNMA2 paraneoplastic Ma antigen 2 0.0067134
SQSTM1 sequestosome 1 0.00667676
COL7A1 collagen, type VII, alpha 1 0.00666845
KRT14 keratin 14, type I 0.00665483
MX1 MX dynamin-like GTPase 1 0.00665206
FTH1 ferritin, heavy polypeptide 1 0.00663701
BCL3 B-cell CLL/lymphoma 3 0.00660607
MT1G metallothionein 1G 0.00660157
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00658824
ZNF185 zinc finger protein 185 (LIM domain) 0.0065865
CA12 carbonic anhydrase XII 0.00657086
SMAD3 SMAD family member 3 0.00655622
CXCL10 chemokine (C-X-C motif) ligand 10 0.00653801
HSPB8 heat shock 22kDa protein 8 0.00651895
SCGB2A1 secretoglobin, family 2A, member 1 0.00649802
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00649057
KLK6 kallikrein-related peptidase 6 0.00648315
HOMER3 homer scaffolding protein 3 0.00647645
HSPB1 heat shock 27kDa protein 1 0.00646727
DMTF1 cyclin D binding myb-like transcription factor 1 0.00640203
MTUS1 microtubule associated tumor suppressor 1 0.00639663
IL32 interleukin 32 0.00639135
HMOX1 heme oxygenase 1 0.00637178
MITF microphthalmia-associated transcription factor 0.0063505
SGCE sarcoglycan, epsilon 0.00631071
TPP1 tripeptidyl peptidase I 0.00628672
COL6A1 collagen, type VI, alpha 1 0.00625076
FGF1 fibroblast growth factor 1 (acidic) 0.00623129
TJP2 tight junction protein 2 0.00620842
CNTN1 contactin 1 0.00617762
FSCN1 fascin actin-bundling protein 1 0.00615203
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00612997
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00612171
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00610649
GPR137B G protein-coupled receptor 137B 0.00609565
NLRP2 NLR family, pyrin domain containing 2 0.00609487
AGRN agrin 0.00609224
CXCL8 chemokine (C-X-C motif) ligand 8 0.00608932
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00608607
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00608333
SNAI2 snail family zinc finger 2 0.00603067
RAB9A RAB9A, member RAS oncogene family 0.00602187
COL5A2 collagen, type V, alpha 2 0.00601446
GRB10 growth factor receptor-bound protein 10 0.00600809
PLK2 polo-like kinase 2 0.00599693
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.00599273
MT1X metallothionein 1X 0.00598685
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00598181
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00593911
AOC1 amine oxidase, copper containing 1 0.00592893
ZC3H12A zinc finger CCCH-type containing 12A 0.00589177
CALML5 calmodulin-like 5 0.00588655
MT1H metallothionein 1H 0.0058789
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00587075
LYST lysosomal trafficking regulator 0.00586404
DOCK9 dedicator of cytokinesis 9 0.00585418
GGT1 gamma-glutamyltransferase 1 0.00582148
SPRED2 sprouty-related, EVH1 domain containing 2 0.00581387
AMDHD2 amidohydrolase domain containing 2 0.00581127
CCNB1 cyclin B1 0.00578046
SST somatostatin 0.0057789
CTSG cathepsin G 0.00577111
ANKRD10 ankyrin repeat domain 10 0.00573528
RIN2 Ras and Rab interactor 2 0.00570889
PALLD palladin, cytoskeletal associated protein 0.00570726
CALB1 calbindin 1, 28kDa 0.0056972
CCNG2 cyclin G2 0.00567874
OASL 2'-5'-oligoadenylate synthetase-like 0.00567216
NPC1 Niemann-Pick disease, type C1 0.00565946
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.00563945
PTGES prostaglandin E synthase 0.00561663
FNBP1 formin binding protein 1 0.00561517
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00559815
RHOBTB3 Rho-related BTB domain containing 3 0.00559674
ADRB2 adrenoceptor beta 2, surface 0.00559207
S100A11 S100 calcium binding protein A11 0.00558894
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00555974
ACTN4 actinin, alpha 4 0.00554087
FCHO1 FCH domain only 1 0.00549273
CLTB clathrin, light chain B 0.00548613
LY75 lymphocyte antigen 75 0.00546827
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.00546781
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00543643
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.00542867
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00542858
RUNX3 runt-related transcription factor 3 0.00542594
WASL Wiskott-Aldrich syndrome-like 0.00540614
CAV1 caveolin 1, caveolae protein, 22kDa 0.00540216
SOX9 SRY (sex determining region Y)-box 9 0.00539862
RHOF ras homolog family member F (in filopodia) 0.00539816
CTSL cathepsin L 0.00538101
MET MET proto-oncogene, receptor tyrosine kinase 0.00537034
CXCL13 chemokine (C-X-C motif) ligand 13 0.00536904
COL15A1 collagen, type XV, alpha 1 0.00535975
MID1 midline 1 0.00534669
FA2H fatty acid 2-hydroxylase 0.00533292
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.00533125
ALCAM activated leukocyte cell adhesion molecule 0.00532433
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.0053179
EZR ezrin 0.00531356
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00530857
CTNND1 catenin (cadherin-associated protein), delta 1 0.00530855
MT1E metallothionein 1E 0.00530155
IFI44 interferon-induced protein 44 0.0052977
AIM2 absent in melanoma 2 0.00529753
RTN2 reticulon 2 0.00529745
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00528569
SAMD9 sterile alpha motif domain containing 9 0.00527339
PLAT plasminogen activator, tissue 0.0052582
TENT5A terminal nucleotidyltransferase 5A 0.00525515
PLPP2 phospholipid phosphatase 2 0.0052522
RBM47 RNA binding motif protein 47 0.00524911
CLIP2 CAP-GLY domain containing linker protein 2 0.00523791
AMOTL2 angiomotin like 2 0.00521434
ZMYM2 zinc finger, MYM-type 2 0.00520871
LYPD3 LY6/PLAUR domain containing 3 0.00520755
RGS2 regulator of G-protein signaling 2 0.00520644
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00520258
JAG1 jagged 1 0.0051976
HOXB6 homeobox B6 0.00518779
DUSP10 dual specificity phosphatase 10 0.00518496
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00518272
ASS1 argininosuccinate synthase 1 0.00516591
SPATA20 spermatogenesis associated 20 0.00514471
TUFT1 tuftelin 1 0.00513486
FAM50A family with sequence similarity 50, member A 0.00512799
AHNAK AHNAK nucleoprotein 0.00512114
IGFBP4 insulin-like growth factor binding protein 4 0.00511313
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00508778
KLF4 Kruppel-like factor 4 (gut) 0.0050873
CRYBG1 crystallin beta-gamma domain containing 1 0.00508446
ZEB1 zinc finger E-box binding homeobox 1 0.00507691
ACTN1 actinin, alpha 1 0.00507644
LIMCH1 LIM and calponin homology domains 1 0.00505468
PDGFD platelet derived growth factor D 0.00505089
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00504626
HSPA2 heat shock 70kDa protein 2 0.00504287
TNIP1 TNFAIP3 interacting protein 1 0.0050301
IL6 interleukin 6 0.00500502
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.00498072
TFRC transferrin receptor 0.00497922
SAMD4A sterile alpha motif domain containing 4A 0.00497597
MBNL2 muscleblind-like splicing regulator 2 0.00495861
DAPK1 death-associated protein kinase 1 0.00495381
ITGAV integrin, alpha V 0.00495165
SPON1 spondin 1, extracellular matrix protein 0.00494546
ETHE1 ethylmalonic encephalopathy 1 0.00493599
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.0049357
FSTL1 follistatin-like 1 0.00493175
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00492333
MTCL1 microtubule crosslinking factor 1 0.00491558
SP110 SP110 nuclear body protein 0.00491496
FGFR1 fibroblast growth factor receptor 1 0.00490937
TUBA4A tubulin, alpha 4a 0.00490459
LAMB3 laminin, beta 3 0.00489704
UPP1 uridine phosphorylase 1 0.00488942
H1-2 H1.2 linker histone, cluster member 0.00487758
C14ORF132 chromosome 14 open reading frame 132 0.00487124
JUNB jun B proto-oncogene 0.00487082
CTSD cathepsin D 0.00486643
ATF7IP activating transcription factor 7 interacting protein 0.00486571
STAB1 stabilin 1 0.00486414
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00486159
GOLIM4 golgi integral membrane protein 4 0.00486091
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00485933
FOXO4 forkhead box O4 0.0048588
CST6 cystatin E/M 0.00485798
ADAM8 ADAM metallopeptidase domain 8 0.00484719
RSAD2 radical S-adenosyl methionine domain containing 2 0.00484415
TUBB6 tubulin, beta 6 class V 0.00484411
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00484235
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.0048408
WWC1 WW and C2 domain containing 1 0.00484069
DST dystonin 0.00484023
KLK8 kallikrein-related peptidase 8 0.00482952
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00482878
OPTN optineurin 0.00482713
ANGPTL2 angiopoietin-like 2 0.00482431
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00481833
BCAS1 breast carcinoma amplified sequence 1 0.00481406
DEFB1 defensin, beta 1 0.0048117
CTSK cathepsin K 0.00480718
TM9SF3 transmembrane 9 superfamily member 3 0.00480281
RGS13 regulator of G-protein signaling 13 0.00478689
TRIB3 tribbles pseudokinase 3 0.00477628
PRSS3 protease, serine, 3 0.00477087
IGF1R insulin-like growth factor 1 receptor 0.00476926
GRAMD2B GRAM domain containing 2B 0.00476892
EPHA2 EPH receptor A2 0.00476731
LPAR1 lysophosphatidic acid receptor 1 0.00476

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0165144
MGP matrix Gla protein -0.0125274
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.010422
LTF lactotransferrin -0.0102621
NTS neurotensin -0.00973479
TSPYL5 TSPY-like 5 -0.00948247
GSTA1 glutathione S-transferase alpha 1 -0.00903832
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00881778
GLUL glutamate-ammonia ligase -0.00864901
NUSAP1 nucleolar and spindle associated protein 1 -0.00863652
CD52 CD52 molecule -0.00841821
PRDX2 peroxiredoxin 2 -0.0083911
AUTS2 autism susceptibility candidate 2 -0.00835864
NRGN neurogranin (protein kinase C substrate, RC3) -0.00807543
NELL2 NEL-like 2 (chicken) -0.0077825
NPTX2 neuronal pentraxin II -0.00773961
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00759032
CES1 carboxylesterase 1 -0.00739615
FHL1 four and a half LIM domains 1 -0.00732569
GTPBP8 GTP-binding protein 8 (putative) -0.00726667
CD2 CD2 molecule -0.00720367
NRN1 neuritin 1 -0.00715876
FGG fibrinogen gamma chain -0.0071329
HBB hemoglobin, beta -0.00707401
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00704873
RPIA ribose 5-phosphate isomerase A -0.00703148
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00696748
AKAP7 A kinase (PRKA) anchor protein 7 -0.00689045
NDN necdin, melanoma antigen (MAGE) family member -0.00676108
LTA4H leukotriene A4 hydrolase -0.00670592
OLFM1 olfactomedin 1 -0.00669465
KRT13 keratin 13, type I -0.00668223
KDM5D lysine (K)-specific demethylase 5D -0.00666606
ZBTB16 zinc finger and BTB domain containing 16 -0.00666437
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.00666428
TMEM14B transmembrane protein 14B -0.00658606
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00655169
LTBP1 latent transforming growth factor beta binding protein 1 -0.00648909
RNASE6 ribonuclease, RNase A family, k6 -0.00645691
RAB4A RAB4A, member RAS oncogene family -0.00645519
SPC25 SPC25, NDC80 kinetochore complex component -0.0064344
ACAT2 acetyl-CoA acetyltransferase 2 -0.00639473
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0063829
C7 complement component 7 -0.00636164
MPZL2 myelin protein zero-like 2 -0.00633036
NPY1R neuropeptide Y receptor Y1 -0.00629328
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00621441
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00618869
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00617296
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00617244
ORM1 orosomucoid 1 -0.00615805
SNX10 sorting nexin 10 -0.00609089
LARS1 leucyl-tRNA synthetase 1 -0.00607348
CPVL carboxypeptidase, vitellogenic-like -0.0060401
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -0.00603536
GRB14 growth factor receptor-bound protein 14 -0.00600554
HMGN3 high mobility group nucleosomal binding domain 3 -0.00598643
THYN1 thymocyte nuclear protein 1 -0.00597424
THAP11 THAP domain containing 11 -0.00592583
AHSG alpha-2-HS-glycoprotein -0.00592134
APOB apolipoprotein B -0.0059059
ADI1 acireductone dioxygenase 1 -0.0059037
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00588568
AKR1C2 aldo-keto reductase family 1, member C2 -0.00579966
PLN phospholamban -0.00579047
SFTPD surfactant protein D -0.0057828
LYZ lysozyme -0.00571757
SORBS2 sorbin and SH3 domain containing 2 -0.00570186
CHEK2 checkpoint kinase 2 -0.0056805
WIF1 WNT inhibitory factor 1 -0.0056777
ZNF652 zinc finger protein 652 -0.00560967
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00559623
OIP5 Opa interacting protein 5 -0.00558269
KIF20A kinesin family member 20A -0.00551374
TSPYL1 TSPY-like 1 -0.00547919
SDC2 syndecan 2 -0.00545423
SIRT3 sirtuin 3 -0.00544877
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00543946
GPC3 glypican 3 -0.00542876
NREP neuronal regeneration related protein -0.0054261
CLIC1 chloride intracellular channel 1 -0.00541212
CADPS2 Ca++-dependent secretion activator 2 -0.00540366
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00539114
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.0053722
ARG2 arginase 2 -0.00537045
TMSB15A thymosin beta 15a -0.0053675
APOA1 apolipoprotein A-I -0.00535464
NGRN neugrin, neurite outgrowth associated -0.00533328
A2M alpha-2-macroglobulin -0.00532822
GREB1 growth regulation by estrogen in breast cancer 1 -0.00531314
METTL7A methyltransferase like 7A -0.00527784
GIMAP6 GTPase, IMAP family member 6 -0.00525332
HMGN4 high mobility group nucleosomal binding domain 4 -0.00522761
MYH11 myosin, heavy chain 11, smooth muscle -0.00520134
ZW10 zw10 kinetochore protein -0.00519382
APOA2 apolipoprotein A-II -0.0051883
IGFBP5 insulin-like growth factor binding protein 5 -0.00517479
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00516321
FZD6 frizzled class receptor 6 -0.00516215
TRPS1 trichorhinophalangeal syndrome I -0.0051411
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00513871
CCNA2 cyclin A2 -0.00513341
CCR2 chemokine (C-C motif) receptor 2 -0.00512173
PAK1IP1 PAK1 interacting protein 1 -0.00511246
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00509738
SOX11 SRY (sex determining region Y)-box 11 -0.00508717
SFTPA2 surfactant protein A2 -0.0050817
PGD phosphogluconate dehydrogenase -0.00505214
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -0.00503146
DCAF10 DDB1 and CUL4 associated factor 10 -0.00500259
SPRR3 small proline-rich protein 3 -0.00500096
PER1 period circadian clock 1 -0.00499878
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.00499458
PSRC1 proline/serine-rich coiled-coil 1 -0.00498117
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -0.00497882
TAGLN transgelin -0.00494487
IFT52 intraflagellar transport 52 -0.00493499
PRKD3 protein kinase D3 -0.00493154
F3 coagulation factor III (thromboplastin, tissue factor) -0.00493012
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00492006
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00491669
HAT1 histone acetyltransferase 1 -0.00491071
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00489358
IGSF6 immunoglobulin superfamily, member 6 -0.00487683
AKIRIN1 akirin 1 -0.00484373
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00483589
TSPAN6 tetraspanin 6 -0.0048187
CTSZ cathepsin Z -0.00481183
FABP1 fatty acid binding protein 1, liver -0.00480449
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00478882
SSR1 signal sequence receptor, alpha -0.0047586
ICAM2 intercellular adhesion molecule 2 -0.00475629
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00473468
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.00472031
HMGB2 high mobility group box 2 -0.00471545
NMT2 N-myristoyltransferase 2 -0.00470931
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0047091
SRSF7 serine/arginine-rich splicing factor 7 -0.00470407
GPX7 glutathione peroxidase 7 -0.00468899
PRKCQ protein kinase C, theta -0.00467596
ADK adenosine kinase -0.00467226
POMZP3 POM121 and ZP3 fusion -0.0046651
MAP2K6 mitogen-activated protein kinase kinase 6 -0.00466064
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.00464429
BRD2 bromodomain containing 2 -0.00460987
ING3 inhibitor of growth family, member 3 -0.00460881
NEK2 NIMA-related kinase 2 -0.00459761
APOH apolipoprotein H (beta-2-glycoprotein I) -0.00459053
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00457598
ZNF274 zinc finger protein 274 -0.00456269
GTF2H5 general transcription factor IIH, polypeptide 5 -0.00456224
PCYOX1 prenylcysteine oxidase 1 -0.00449845
MOCOS molybdenum cofactor sulfurase -0.00449497
TBC1D16 TBC1 domain family, member 16 -0.00449347
ISYNA1 inositol-3-phosphate synthase 1 -0.00449347
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00448787
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -0.00448519
ODC1 ornithine decarboxylase 1 -0.004479
CCNF cyclin F -0.00445157
AKR1C1 aldo-keto reductase family 1, member C1 -0.00443184
HMGB3 high mobility group box 3 -0.00442959
TMEM204 transmembrane protein 204 -0.0044271
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) -0.00442647
POLB polymerase (DNA directed), beta -0.00442489
CCDC69 coiled-coil domain containing 69 -0.00441577
FMO3 flavin containing monooxygenase 3 -0.00441329
RPL13 ribosomal protein L13 -0.00441232
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00440961
SUMO3 small ubiquitin-like modifier 3 -0.00440726
RPS5 ribosomal protein S5 -0.00440451
ITM2A integral membrane protein 2A -0.00440051
ACYP2 acylphosphatase 2, muscle type -0.00439647
ANG angiogenin, ribonuclease, RNase A family, 5 -0.00439546
DEK DEK proto-oncogene -0.00439323
BPIFA1 BPI fold containing family A, member 1 -0.00439209
MEF2C myocyte enhancer factor 2C -0.00438437
CD302 CD302 molecule -0.00437997
BAX BCL2-associated X protein -0.00437926
SIRT5 sirtuin 5 -0.00437403
SV2A synaptic vesicle glycoprotein 2A -0.00437279
RPL10A ribosomal protein L10a -0.0043715
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.00436132
NIP7 NIP7, nucleolar pre-rRNA processing protein -0.00435348
GCA grancalcin, EF-hand calcium binding protein -0.00434707
PEX11A peroxisomal biogenesis factor 11 alpha -0.00434589
BIRC5 baculoviral IAP repeat containing 5 -0.00434575
MECOM MDS1 and EVI1 complex locus -0.00434487
CPB2 carboxypeptidase B2 (plasma) -0.00434479
RWDD1 RWD domain containing 1 -0.00434334
FAM149A family with sequence similarity 149, member A -0.00434214
FLOT2 flotillin 2 -0.00433948
CPM carboxypeptidase M -0.00433656
DCXR dicarbonyl/L-xylulose reductase -0.00433609
MSMB microseminoprotein, beta- -0.0043322
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00432461
DAXX death-domain associated protein -0.00430127
NKX3-1 NK3 homeobox 1 -0.00429287
ZBED8 zinc finger, BED-type containing 8 -0.00428476
GSTT1 glutathione S-transferase theta 1 -0.00428301
TPGS2 tubulin polyglutamylase complex subunit 2 -0.00427837
DHCR7 7-dehydrocholesterol reductase -0.004275
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00426799
FOXJ2 forkhead box J2 -0.00426789
KLHL23 kelch-like family member 23 -0.00424295
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00424052
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -0.00423839
CD48 CD48 molecule -0.00423756
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -0.00422679
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00422564
PSPH phosphoserine phosphatase -0.00422396
MYL9 myosin, light chain 9, regulatory -0.00422305
SEPHS1 selenophosphate synthetase 1 -0.00421924
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00421396
CD300A CD300a molecule -0.00421266
ADCY1 adenylate cyclase 1 (brain) -0.00420987
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00420473
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -0.0042024
ERG28 ergosterol biosynthesis 28 homolog -0.00419738
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00418598
LPAR6 lysophosphatidic acid receptor 6 -0.00418566
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00418217
ATF1 activating transcription factor 1 -0.00418036
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.0041767
STK16 serine/threonine kinase 16 -0.00417536
RGCC regulator of cell cycle -0.0041736
MAGT1 magnesium transporter 1 -0.0041699
RTN1 reticulon 1 -0.0041674
GTSE1 G-2 and S-phase expressed 1 -0.00416581
PIMREG PICALM interacting mitotic regulator -0.00416493
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -0.00415783
NOTCH3 notch 3 -0.00414221
TGIF2 TGFB-induced factor homeobox 2 -0.00413543
SSBP2 single-stranded DNA binding protein 2 -0.00413172
ZNF329 zinc finger protein 329 -0.004127
EDN1 endothelin 1 -0.00411457
MYH10 myosin, heavy chain 10, non-muscle -0.00411451
ALB albumin -0.0041138
SHOX2 short stature homeobox 2 -0.00411368
TMEM231 transmembrane protein 231 -0.00411148
APOM apolipoprotein M -0.00410996
BCLAF1 BCL2-associated transcription factor 1 -0.00409744
VSNL1 visinin-like 1 -0.00409173
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -0.00409049
RSL24D1 ribosomal L24 domain containing 1 -0.00408068
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00407627
ASGR2 asialoglycoprotein receptor 2 -0.00406626
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide -0.0040564
RNF130 ring finger protein 130 -0.00405403
TREM1 triggering receptor expressed on myeloid cells 1 -0.0040539
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -0.00405351