SRF Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description serum response factor (c-fos serum response element-binding transcription factor)|This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 6722)
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Genes

40 target genes of the SRF transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BZRAP1-AS1 BZRAP1 antisense RNA 1
CALD1 caldesmon 1
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
DGKH diacylglycerol kinase, eta
DIXDC1 DIX domain containing 1
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EPSTI1 epithelial stromal interaction 1 (breast)
FGFRL1 fibroblast growth factor receptor-like 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
HOXB-AS3 HOXB cluster antisense RNA 3
IER2 immediate early response 2
KDM3A lysine (K)-specific demethylase 3A
LINC00841 long intergenic non-protein coding RNA 841
LOC100240735 uncharacterized LOC100240735
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAT2A methionine adenosyltransferase II, alpha
MBNL1 muscleblind-like splicing regulator 1
MBTD1 mbt domain containing 1
MIR4270 microRNA 4270
MIR4505 microRNA 4505
MT-TA tRNA
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NPAS2 neuronal PAS domain protein 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
PRM1 protamine 1
RNF167 ring finger protein 167
RYR3 ryanodine receptor 3
SHROOM3 shroom family member 3
SMTN smoothelin
SNAP25 synaptosomal-associated protein, 25kDa
SNORD112 small nucleolar RNA, C/D box 112
SON SON DNA binding protein
SRF serum response factor (c-fos serum response element-binding transcription factor)
TAGLN transgelin
TNNC1 troponin C type 1 (slow)
TPM4 tropomyosin 4
VCL vinculin