| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | serglycin|This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 5552) |
| External Link | https://ncbi.nlm.nih.gov/gene/5552 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the SRGN gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PUF60 | poly-U binding splicing factor 60KDa | 0.0225958 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.0193455 |
| GAS1 | growth arrest-specific 1 | 0.0167448 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0166421 |
| SYNM | synemin, intermediate filament protein | 0.0144847 |
| TNC | tenascin C | 0.01394 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0130656 |
| CHRDL1 | chordin-like 1 | 0.0129396 |
| NFIB | nuclear factor I/B | 0.0128329 |
| HELLS | helicase, lymphoid-specific | 0.012743 |
| HEATR1 | HEAT repeat containing 1 | 0.0125961 |
| C7 | complement component 7 | 0.0125068 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0123527 |
| GOLGA8A | golgin A8 family, member A | 0.0123367 |
| TPM2 | tropomyosin 2 (beta) | 0.0122129 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.0120673 |
| DES | desmin | 0.0120632 |
| MPDZ | multiple PDZ domain protein | 0.0119884 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0119224 |
| SLC43A3 | solute carrier family 43, member 3 | 0.0118916 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0116632 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0115344 |
| MCAM | melanoma cell adhesion molecule | 0.0111964 |
| HSPA1A | heat shock 70kDa protein 1A | 0.011156 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0110895 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0110893 |
| ABLIM1 | actin binding LIM protein 1 | 0.011061 |
| C1S | complement component 1, s subcomponent | 0.0109691 |
| PROM1 | prominin 1 | 0.0109088 |
| C1R | complement component 1, r subcomponent | 0.0108058 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0107838 |
| MAOB | monoamine oxidase B | 0.0107684 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0105289 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.0104499 |
| MATN2 | matrilin 2 | 0.0104414 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0103965 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0103306 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.0102849 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0102282 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0102264 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.0102237 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.0101407 |
| MYBPC1 | myosin binding protein C, slow type | 0.0100826 |
| SETBP1 | SET binding protein 1 | 0.00997685 |
| IRS2 | insulin receptor substrate 2 | 0.00993602 |
| KRT23 | keratin 23, type I | 0.00985307 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.0098394 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00972359 |
| CRYAB | crystallin, alpha B | 0.00960133 |
| SACS | sacsin molecular chaperone | 0.00955026 |
| RBPMS | RNA binding protein with multiple splicing | 0.00950979 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00947099 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00938717 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00927218 |
| AOX1 | aldehyde oxidase 1 | 0.00925087 |
| NES | nestin | 0.0091187 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00906121 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00901599 |
| PALMD | palmdelphin | 0.00896493 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00893713 |
| GPM6B | glycoprotein M6B | 0.00891537 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00888715 |
| CFH | complement factor H | 0.0088848 |
| KRT14 | keratin 14, type I | 0.00880923 |
| LHFP | lipoma HMGIC fusion partner | 0.00878787 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00877638 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0087041 |
| C3 | complement component 3 | 0.00869079 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00863412 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00862406 |
| DPT | dermatopontin | 0.00858877 |
| TSPYL5 | TSPY-like 5 | 0.00858459 |
| TUBB6 | tubulin, beta 6 class V | 0.0085631 |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.00855119 |
| FBLN5 | fibulin 5 | 0.0085142 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00849904 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00849344 |
| TNS1 | tensin 1 | 0.0084745 |
| OXTR | oxytocin receptor | 0.00843003 |
| MMP3 | matrix metallopeptidase 3 | 0.00842073 |
| ADAMTSL3 | ADAMTS-like 3 | 0.00840745 |
| GLA | galactosidase, alpha | 0.00840559 |
| RET | ret proto-oncogene | 0.00832364 |
| KLHL41 | kelch-like family member 41 | 0.00828048 |
| KLK6 | kallikrein-related peptidase 6 | 0.008238 |
| NRCAM | neuronal cell adhesion molecule | 0.00818067 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00815821 |
| FHL1 | four and a half LIM domains 1 | 0.00813747 |
| GSDME | gasdermin E | 0.00811302 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00809655 |
| CHEK2 | checkpoint kinase 2 | 0.00800738 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00799337 |
| NOTCH2NL | notch 2 N-terminal like | 0.00795863 |
| RBM39 | RNA binding motif protein 39 | 0.00794118 |
| INSR | insulin receptor | 0.00793391 |
| SCRIB | scribbled planar cell polarity protein | 0.00791334 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00790536 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00789826 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00785416 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00780614 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00779527 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00777381 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00775667 |
| PLSCR4 | phospholipid scramblase 4 | 0.0077438 |
| COL4A1 | collagen, type IV, alpha 1 | 0.00774054 |
| FMO3 | flavin containing monooxygenase 3 | 0.00773552 |
| PLCE1 | phospholipase C, epsilon 1 | 0.00772501 |
| DZIP1 | DAZ interacting zinc finger protein 1 | 0.007711 |
| TMEM100 | transmembrane protein 100 | 0.00770169 |
| RCAN1 | regulator of calcineurin 1 | 0.00769748 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00768481 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00764708 |
| NUCLEOLIN | nucleolin multifunctional protein | 0.00763769 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | 0.00762591 |
| DMD | dystrophin | 0.00762531 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00760714 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00759057 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 | 0.00759015 |
| PXDN | peroxidasin | 0.0075813 |
| TYRP1 | tyrosinase-related protein 1 | 0.00754525 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.00753772 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00751655 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00750168 |
| MFAP5 | microfibrillar associated protein 5 | 0.00747245 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00746743 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00746376 |
| DST | dystonin | 0.00746134 |
| PDLIM4 | PDZ and LIM domain 4 | 0.0074347 |
| IL1R1 | interleukin 1 receptor, type I | 0.00741849 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00740739 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00739156 |
| FNBP1 | formin binding protein 1 | 0.00736229 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00735728 |
| APOD | apolipoprotein D | 0.00735416 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00734459 |
| MYOZ2 | myozenin 2 | 0.007316 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00729277 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00729215 |
| BIN1 | bridging integrator 1 | 0.00729081 |
| BICC1 | BicC family RNA binding protein 1 | 0.00728715 |
| ASRGL1 | asparaginase like 1 | 0.00727242 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00725562 |
| GPC4 | glypican 4 | 0.00724753 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00723138 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.00722401 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00722319 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0072167 |
| LEPR | leptin receptor | 0.00718501 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00716063 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | 0.00712924 |
| KLK10 | kallikrein-related peptidase 10 | 0.00711608 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00711103 |
| NNMT | nicotinamide N-methyltransferase | 0.00709003 |
| FGL1 | fibrinogen-like 1 | 0.00707612 |
| GRB14 | growth factor receptor-bound protein 14 | 0.0070689 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0070138 |
| CALCA | calcitonin-related polypeptide alpha | 0.00697675 |
| SMTN | smoothelin | 0.00696239 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00694998 |
| MIPEP | mitochondrial intermediate peptidase | 0.00694804 |
| MME | membrane metallo-endopeptidase | 0.00694765 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00694395 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00693721 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00693523 |
| KRT7 | keratin 7, type II | 0.00693344 |
| NFASC | neurofascin | 0.00690838 |
| RBM26 | RNA binding motif protein 26 | 0.00689833 |
| BMP6 | bone morphogenetic protein 6 | 0.00687795 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00687596 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00686648 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00686575 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00685819 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.0068489 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00684047 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00683741 |
| FADS1 | fatty acid desaturase 1 | 0.00683016 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00682158 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00679975 |
| ITGA7 | integrin, alpha 7 | 0.00679408 |
| SASH1 | SAM and SH3 domain containing 1 | 0.00678543 |
| HMG20B | high mobility group 20B | 0.00678416 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00677494 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00675289 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00674957 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00672731 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | 0.0067253 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00671425 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00669172 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.00667771 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00667649 |
| FBLN2 | fibulin 2 | 0.00667599 |
| TTN | titin | 0.00664533 |
| KLHL21 | kelch-like family member 21 | 0.00663835 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.00662262 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00661932 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00661639 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00658825 |
| MT1X | metallothionein 1X | 0.00658646 |
| FSTL1 | follistatin-like 1 | 0.00658137 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.00657931 |
| RAPSN | receptor-associated protein of the synapse | 0.00656704 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.00656028 |
| MGLL | monoglyceride lipase | 0.00653222 |
| BCHE | butyrylcholinesterase | 0.00652807 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0065221 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00651799 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.0065144 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 | 0.0065117 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00651118 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00649957 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00649499 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00647502 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.00647181 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00646916 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00645566 |
| FERMT2 | fermitin family member 2 | 0.00645271 |
| CASQ2 | calsequestrin 2 (cardiac muscle) | 0.00642786 |
| BBX | bobby sox homolog (Drosophila) | 0.00642381 |
| KLF6 | Kruppel-like factor 6 | 0.00640553 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00637644 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00636926 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.00636576 |
| SRRT | serrate, RNA effector molecule | 0.00636563 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00636121 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00635693 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00635465 |
| ADCY9 | adenylate cyclase 9 | 0.00635299 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00633801 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00632782 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00632562 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00631545 |
| OGN | osteoglycin | 0.0063034 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00630094 |
| FAM13B | family with sequence similarity 13, member B | 0.00629826 |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.00629145 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00627825 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00627465 |
| PSPC1 | paraspeckle component 1 | 0.00625668 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.0062337 |
| SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | 0.00619336 |
| MMP1 | matrix metallopeptidase 1 | 0.00618092 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00614884 |
| C8ORF33 | chromosome 8 open reading frame 33 | 0.0061442 |
| FANCI | Fanconi anemia, complementation group I | 0.00610937 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00609718 |
| MEOX2 | mesenchyme homeobox 2 | 0.00608515 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00608312 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | 0.00607831 |
| ESR1 | estrogen receptor 1 | 0.00607694 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00605806 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SYNGR3 | synaptogyrin 3 | -0.0192268 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0179083 |
| GNAS | GNAS complex locus | -0.0174109 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0165219 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0154528 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0153011 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0149429 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.0142931 |
| SIRT3 | sirtuin 3 | -0.0138556 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0137702 |
| S100A9 | S100 calcium binding protein A9 | -0.0137606 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0127294 |
| EVI2A | ecotropic viral integration site 2A | -0.0123525 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.0122793 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.012168 |
| CLEC7A | C-type lectin domain family 7, member A | -0.0121121 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0120525 |
| PLBD1 | phospholipase B domain containing 1 | -0.0120419 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0118465 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0118375 |
| S100A8 | S100 calcium binding protein A8 | -0.0115919 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.0114241 |
| GPR65 | G protein-coupled receptor 65 | -0.0111653 |
| H1-2 | H1.2 linker histone, cluster member | -0.0111529 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.0110219 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.0110188 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.0108592 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0108178 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0107988 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.0106844 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0105734 |
| DCK | deoxycytidine kinase | -0.0104277 |
| ACOT13 | acyl-CoA thioesterase 13 | -0.0103704 |
| KRT19 | keratin 19, type I | -0.0102605 |
| CLIC3 | chloride intracellular channel 3 | -0.0102565 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0101394 |
| TGFB1 | transforming growth factor, beta 1 | -0.0101208 |
| NMU | neuromedin U | -0.0100239 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00991928 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00990085 |
| HOPX | HOP homeobox | -0.00985821 |
| MAGEA3 | melanoma antigen family A3 | -0.00979746 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00975154 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00964577 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | -0.00961656 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00961476 |
| LYZ | lysozyme | -0.0095752 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00951915 |
| CHKB | choline kinase beta | -0.00944621 |
| MARCKSL1 | MARCKS-like 1 | -0.00934537 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00925092 |
| MECOM | MDS1 and EVI1 complex locus | -0.00918536 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0091648 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00913767 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.0090792 |
| PEG10 | paternally expressed 10 | -0.00906934 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00906195 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00893574 |
| LCN2 | lipocalin 2 | -0.008899 |
| LRRC17 | leucine rich repeat containing 17 | -0.00888087 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00886104 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00884457 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00881622 |
| COPS4 | COP9 signalosome subunit 4 | -0.00881159 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00880671 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.0087187 |
| REEP5 | receptor accessory protein 5 | -0.00871723 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.0086956 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00865717 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00863481 |
| BIN2 | bridging integrator 2 | -0.0086146 |
| PDGFC | platelet derived growth factor C | -0.00854298 |
| DUOX2 | dual oxidase 2 | -0.00846116 |
| GPR171 | G protein-coupled receptor 171 | -0.00844676 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00844425 |
| ANXA4 | annexin A4 | -0.00844365 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00844157 |
| OLFM4 | olfactomedin 4 | -0.00843265 |
| TMEM50B | transmembrane protein 50B | -0.00836063 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00826617 |
| CDC42 | cell division cycle 42 | -0.00826173 |
| S100A10 | S100 calcium binding protein A10 | -0.00823288 |
| CD48 | CD48 molecule | -0.00819584 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00818645 |
| FPR1 | formyl peptide receptor 1 | -0.00818178 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.00817634 |
| S100A2 | S100 calcium binding protein A2 | -0.00816524 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00814083 |
| CLDN4 | claudin 4 | -0.00812319 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0080564 |
| AREG | amphiregulin | -0.00805596 |
| PCP4 | Purkinje cell protein 4 | -0.00805175 |
| CLCA1 | chloride channel accessory 1 | -0.0080132 |
| HDDC2 | HD domain containing 2 | -0.0079803 |
| MRPL40 | mitochondrial ribosomal protein L40 | -0.00790937 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00790779 |
| PRSS3 | protease, serine, 3 | -0.00789133 |
| CLDN7 | claudin 7 | -0.00788496 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00786325 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00785237 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00775619 |
| POLB | polymerase (DNA directed), beta | -0.00775603 |
| MXRA7 | matrix-remodelling associated 7 | -0.00771071 |
| LY96 | lymphocyte antigen 96 | -0.00765408 |
| C3AR1 | complement component 3a receptor 1 | -0.00764258 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00761824 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00759562 |
| AOC1 | amine oxidase, copper containing 1 | -0.00759381 |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 | -0.00757882 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00757643 |
| MAP7 | microtubule-associated protein 7 | -0.00757397 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00756254 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00755256 |
| CTSZ | cathepsin Z | -0.00754772 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00751105 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | -0.0074905 |
| SNX10 | sorting nexin 10 | -0.00748993 |
| RNF141 | ring finger protein 141 | -0.00748919 |
| ADSL | adenylosuccinate lyase | -0.00748277 |
| COMMD3 | COMM domain containing 3 | -0.00743591 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00743017 |
| CDA | cytidine deaminase | -0.00740006 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.00739845 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00738898 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | -0.00733792 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00730517 |
| IFI44L | interferon-induced protein 44-like | -0.0072833 |
| PRSS8 | protease, serine, 8 | -0.00727442 |
| MRPL17 | mitochondrial ribosomal protein L17 | -0.00724475 |
| CTSS | cathepsin S | -0.00724029 |
| ARG2 | arginase 2 | -0.00722774 |
| C5AR1 | complement component 5a receptor 1 | -0.00718948 |
| MED28 | mediator complex subunit 28 | -0.0071795 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.00717354 |
| KRT18 | keratin 18, type I | -0.00714752 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00713511 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | -0.00713312 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.00707527 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00707425 |
| CTSE | cathepsin E | -0.0070717 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00705158 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00702359 |
| FAM198B | family with sequence similarity 198, member B | -0.00701992 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | -0.00698291 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00698282 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00697717 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00694187 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | -0.00693965 |
| TMEM126B | transmembrane protein 126B | -0.00692882 |
| IL2RB | interleukin 2 receptor, beta | -0.00691471 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00688032 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.0068729 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00687215 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00685778 |
| EPCAM | epithelial cell adhesion molecule | -0.00683786 |
| CYTIP | cytohesin 1 interacting protein | -0.00682358 |
| TSPAN6 | tetraspanin 6 | -0.00681566 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00681419 |
| IL32 | interleukin 32 | -0.00680973 |
| CD86 | CD86 molecule | -0.00680653 |
| ITK | IL2-inducible T-cell kinase | -0.00680587 |
| VAMP5 | vesicle-associated membrane protein 5 | -0.00679548 |
| GALC | galactosylceramidase | -0.00679119 |
| CCDC85B | coiled-coil domain containing 85B | -0.00678771 |
| CREM | cAMP responsive element modulator | -0.00678544 |
| VIL1 | villin 1 | -0.00677682 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00676383 |
| SNRPD2 | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | -0.00674881 |
| CHMP5 | charged multivesicular body protein 5 | -0.00674463 |
| RNF19B | ring finger protein 19B | -0.00673349 |
| PAAF1 | proteasomal ATPase-associated factor 1 | -0.00673037 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.0067275 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00671718 |
| MGAM | maltase-glucoamylase | -0.00670611 |
| CD2 | CD2 molecule | -0.00670519 |
| MLF1 | myeloid leukemia factor 1 | -0.00667933 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00666342 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.0066611 |
| HK2 | hexokinase 2 | -0.00665418 |
| CPE | carboxypeptidase E | -0.0066538 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00664859 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -0.00662855 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00661953 |
| GLUL | glutamate-ammonia ligase | -0.00661452 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00660443 |
| PPT1 | palmitoyl-protein thioesterase 1 | -0.00659802 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.00659394 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00658648 |
| TALDO1 | transaldolase 1 | -0.00657228 |
| PRDX4 | peroxiredoxin 4 | -0.00654608 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00654009 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00653439 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | -0.00652301 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00652087 |
| DENND1B | DENN/MADD domain containing 1B | -0.0065168 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.00650583 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00649862 |
| PLS3 | plastin 3 | -0.00647666 |
| TBL2 | transducin (beta)-like 2 | -0.006443 |
| TLR1 | toll-like receptor 1 | -0.00642945 |
| MAGEA10 | melanoma antigen family A10 | -0.00641456 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0064096 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00640506 |
| GM2A | GM2 ganglioside activator | -0.00639879 |
| GCG | glucagon | -0.00639764 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00639552 |
| TMPRSS2 | transmembrane protease, serine 2 | -0.00638832 |
| PGD | phosphogluconate dehydrogenase | -0.00637033 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00635286 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00634294 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00632953 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | -0.00631881 |
| RGS16 | regulator of G-protein signaling 16 | -0.00630019 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00629747 |
| COLEC12 | collectin sub-family member 12 | -0.00628888 |
| BPI | bactericidal/permeability-increasing protein | -0.00627219 |
| KRT20 | keratin 20, type I | -0.00625567 |
| HIC2 | hypermethylated in cancer 2 | -0.00623653 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.00622774 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | -0.00621097 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00620704 |
| SORT1 | sortilin 1 | -0.00619709 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00616479 |
| TMEM135 | transmembrane protein 135 | -0.00616011 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00615254 |
| DNASE1L1 | deoxyribonuclease I-like 1 | -0.00614388 |
| HBD | hemoglobin, delta | -0.00613548 |
| GOLT1B | golgi transport 1B | -0.00612657 |
| ZNF277 | zinc finger protein 277 | -0.00611938 |
| SST | somatostatin | -0.00610769 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.00610766 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.0061056 |
| RPS5 | ribosomal protein S5 | -0.00610089 |
| TSPAN5 | tetraspanin 5 | -0.00609373 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00608886 |
| TMEM230 | transmembrane protein 230 | -0.00608736 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00608612 |
| TLR4 | toll-like receptor 4 | -0.00608016 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00607566 |
| PKM | pyruvate kinase, muscle | -0.00607359 |
| CTBS | chitobiase, di-N-acetyl- | -0.00605609 |
| DEAF1 | DEAF1 transcription factor | -0.00604511 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00604284 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00604175 |
| TMEM14A | transmembrane protein 14A | -0.00603375 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00602459 |
| ZNF195 | zinc finger protein 195 | -0.00602285 |
| MMP11 | matrix metallopeptidase 11 | -0.00602098 |
