SRGN Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description serglycin|This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 5552)
External Link http://www.ncbi.nlm.nih.gov/gene/5552
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Genes

16 interacting proteins for SRGN from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ALB albumin
BAG6 BCL2-associated athanogene 6
CCL3 chemokine (C-C motif) ligand 3
CD44 CD44 molecule (Indian blood group)
CEP70 centrosomal protein 70kDa
CRELD2 cysteine-rich with EGF-like domains 2
FHL3 four and a half LIM domains 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
MMP9 matrix metallopeptidase 9
PF4 platelet factor 4
PRF1 perforin 1 (pore forming protein)
PSRC1 proline/serine-rich coiled-coil 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
UBQLN4 ubiquilin 4
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VCAN versican