| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/9872438 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in SSR 69071 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMOX1 | heme oxygenase 1 | 2.43 |
| DCHS2 | dachsous cadherin-related 2 | 1.85 |
| ALPK3 | alpha-kinase 3 | 1.64 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | 1.26 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 | 1.12 |
| MIDN | midnolin | 1.03 |
| GPANK1 | G patch domain and ankyrin repeats 1 | 0.92 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 0.91 |
| PUM1 | pumilio RNA-binding family member 1 | 0.86 |
| CCDC18 | coiled-coil domain containing 18 | 0.75 |
| SMOX | spermine oxidase | 0.74 |
| ZNF385B | zinc finger protein 385B | 0.74 |
| PLAUR | plasminogen activator, urokinase receptor | 0.73 |
| DUSP5 | dual specificity phosphatase 5 | 0.72 |
| TGFB1 | transforming growth factor, beta 1 | 0.71 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 0.7 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.69 |
| ADCY10 | adenylate cyclase 10 (soluble) | 0.65 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.65 |
| SRXN1 | sulfiredoxin 1 | 0.64 |
| TRIB1 | tribbles pseudokinase 1 | 0.63 |
| S100A6 | S100 calcium binding protein A6 | 0.61 |
| MIS12 | MIS12 kinetochore complex component | 0.59 |
| TSPYL2 | TSPY-like 2 | 0.59 |
| FHIT | fragile histidine triad | 0.59 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.59 |
| PMF1 | polyamine-modulated factor 1 | 0.59 |
| APOE | apolipoprotein E | 0.58 |
| TXNRD1 | thioredoxin reductase 1 | 0.57 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.57 |
| IFRD1 | interferon-related developmental regulator 1 | 0.57 |
| EWSR1 | EWS RNA-binding protein 1 | 0.57 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | 0.56 |
| ADIRF | adipogenesis regulatory factor | 0.56 |
| SGSH | N-sulfoglucosamine sulfohydrolase | 0.54 |
| SESN2 | sestrin 2 | 0.53 |
| TMEM134 | transmembrane protein 134 | 0.53 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.53 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 0.52 |
| KLHL15 | kelch-like family member 15 | 0.52 |
| RELT | RELT tumor necrosis factor receptor | 0.52 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.52 |
| CBARP | CACN subunit beta associated regulatory protein | 0.51 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.51 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.5 |
| SLC12A8 | solute carrier family 12, member 8 | 0.5 |
| BOLA1 | bolA family member 1 | 0.5 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.5 |
| RAB30 | RAB30, member RAS oncogene family | 0.49 |
| ZNF581 | zinc finger protein 581 | 0.49 |
| ATF6B | activating transcription factor 6 beta | 0.48 |
| RGPD5 | RANBP2-like and GRIP domain containing 5 | 0.47 |
| SFXN5 | sideroflexin 5 | 0.47 |
| S100A14 | S100 calcium binding protein A14 | 0.47 |
| CTSL | cathepsin L | 0.47 |
| BID | BH3 interacting domain death agonist | 0.46 |
| LIN37 | lin-37 DREAM MuvB core complex component | 0.46 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | 0.46 |
| PTRHD1 | peptidyl-tRNA hydrolase domain containing 1 | 0.46 |
| GLCCI1 | glucocorticoid induced 1 | 0.46 |
| ZNRD2 | zinc ribbon domain containing 2 | 0.46 |
| ACTN4 | actinin, alpha 4 | 0.46 |
| ZNF444 | zinc finger protein 444 | 0.46 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.45 |
| SLC38A2 | solute carrier family 38, member 2 | 0.45 |
| SMTN | smoothelin | 0.45 |
| PHLDB3 | pleckstrin homology-like domain, family B, member 3 | 0.44 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.44 |
| TYMP | thymidine phosphorylase | 0.44 |
| FTL | ferritin, light polypeptide | 0.44 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.44 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.44 |
| UBXN8 | UBX domain protein 8 | 0.44 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.44 |
| HBA1 | hemoglobin, alpha 1 | 0.44 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.44 |
| PTRH1 | peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) | 0.44 |
| GPATCH4 | G patch domain containing 4 | 0.43 |
| HAS3 | hyaluronan synthase 3 | 0.43 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.43 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.43 |
| KCTD2 | potassium channel tetramerization domain containing 2 | 0.42 |
| ZSCAN25 | zinc finger and SCAN domain containing 25 | 0.42 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.42 |
| NABP1 | nucleic acid binding protein 1 | 0.42 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.42 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 | 0.42 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.41 |
| MRPL12 | mitochondrial ribosomal protein L12 | 0.41 |
| CBR1 | carbonyl reductase 1 | 0.41 |
| REX1BD | required for excision 1-B domain containing | 0.41 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.41 |
| CCPG1 | cell cycle progression 1 | 0.41 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.4 |
| B3GALT6 | UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 | 0.4 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.4 |
| RNF185 | ring finger protein 185 | 0.4 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.39 |
| CBLC | Cbl proto-oncogene C, E3 ubiquitin protein ligase | 0.39 |
| FAM219A | family with sequence similarity 219, member A | 0.39 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEKHH2 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | -3.38 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -1.38 |
| MT1F | metallothionein 1F | -1.33 |
| ENO1 | enolase 1, (alpha) | -1.3 |
| UROS | uroporphyrinogen III synthase | -1.08 |
| MBNL2 | muscleblind-like splicing regulator 2 | -1.03 |
| H3C1 | H3 clustered histone 1 | -0.93 |
| MSRB2 | methionine sulfoxide reductase B2 | -0.92 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.83 |
| SORT1 | sortilin 1 | -0.82 |
| HYKK | hydroxylysine kinase | -0.79 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | -0.73 |
| COA6 | cytochrome c oxidase assembly factor 6 | -0.72 |
| LTBP3 | latent transforming growth factor beta binding protein 3 | -0.71 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.69 |
| TBC1D30 | TBC1 domain family, member 30 | -0.68 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.67 |
| FZD2 | frizzled class receptor 2 | -0.67 |
| SAC3D1 | SAC3 domain containing 1 | -0.65 |
| MT1L | metallothionein 1L (gene/pseudogene) | -0.65 |
| ACTL8 | actin-like 8 | -0.63 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa | -0.62 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.62 |
| CFAP410 | cilia and flagella associated protein 410 | -0.62 |
| SCPEP1 | serine carboxypeptidase 1 | -0.62 |
| PRSS23 | protease, serine, 23 | -0.6 |
| ABRACL | ABRA C-terminal like | -0.6 |
| UNC13D | unc-13 homolog D (C. elegans) | -0.6 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.59 |
| RGN | regucalcin | -0.58 |
| TNS3 | tensin 3 | -0.58 |
| MT1E | metallothionein 1E | -0.57 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.57 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | -0.57 |
| FAM135A | family with sequence similarity 135, member A | -0.56 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | -0.56 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) | -0.56 |
| CAPN15 | calpain 15 | -0.56 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | -0.55 |
| ZNF827 | zinc finger protein 827 | -0.55 |
| CLIC6 | chloride intracellular channel 6 | -0.55 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.54 |
| CRTC3 | CREB regulated transcription coactivator 3 | -0.54 |
| SCARA3 | scavenger receptor class A, member 3 | -0.53 |
| AGRN | agrin | -0.51 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.51 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.51 |
| TBC1D31 | TBC1 domain family, member 31 | -0.5 |
| NADSYN1 | NAD synthetase 1 | -0.5 |
| KITLG | KIT ligand | -0.5 |
| CTSH | cathepsin H | -0.5 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.5 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | -0.5 |
| MELTF | melanotransferrin | -0.5 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | -0.49 |
| BDNF | brain-derived neurotrophic factor | -0.49 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.49 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.49 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | -0.49 |
| ZNF100 | zinc finger protein 100 | -0.49 |
| SUSD2 | sushi domain containing 2 | -0.49 |
| KLHL22 | kelch-like family member 22 | -0.47 |
| CPD | carboxypeptidase D | -0.47 |
| PRKCQ | protein kinase C, theta | -0.46 |
| COL13A1 | collagen, type XIII, alpha 1 | -0.46 |
| HOXB9 | homeobox B9 | -0.46 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.46 |
| DPP4 | dipeptidyl-peptidase 4 | -0.46 |
| SLC25A39 | solute carrier family 25, member 39 | -0.46 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 | -0.46 |
| DPP7 | dipeptidyl-peptidase 7 | -0.46 |
| HSP90AA4P | heat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene | -0.46 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.46 |
| IGF2R | insulin-like growth factor 2 receptor | -0.45 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.45 |
| LAP3 | leucine aminopeptidase 3 | -0.45 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.45 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.45 |
| ALKBH5 | AlkB family member 5, RNA demethylase | -0.44 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | -0.44 |
| RARG | retinoic acid receptor, gamma | -0.44 |
| RNF4 | ring finger protein 4 | -0.44 |
| GPC4 | glypican 4 | -0.43 |
| PAQR4 | progestin and adipoQ receptor family member IV | -0.43 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | -0.43 |
| C19ORF54 | chromosome 19 open reading frame 54 | -0.43 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | -0.43 |
| FGG | fibrinogen gamma chain | -0.43 |
| MT2A | metallothionein 2A | -0.43 |
| UVRAG | UV radiation resistance associated | -0.42 |
| CAT | catalase | -0.42 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.42 |
| CD276 | CD276 molecule | -0.42 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.42 |
| ESPN | espin | -0.42 |
| C1ORF226 | chromosome 1 open reading frame 226 | -0.41 |
| RTTN | rotatin | -0.41 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | -0.41 |
| FGA | fibrinogen alpha chain | -0.41 |
| DMXL2 | Dmx-like 2 | -0.41 |
