ST486 Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
Description Burkitt Lymphoma cell line (Cancer Dependency Map)
External Link https://depmap.org/portal/cell_line/ACH-000567
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Genes

648 gene knockdowns changing fitness of ST486 relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
SUSD6 sushi domain containing 6 23.5641
ZNF3 zinc finger protein 3 15.862
SYNJ1 synaptojanin 1 14.3769
COPS7B COP9 signalosome subunit 7B 13.7864
LRP10 low density lipoprotein receptor-related protein 10 13.4666
CLEC16A C-type lectin domain family 16, member A 10.9472
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 10.6777
EXOC6 exocyst complex component 6 10.2329
MSL3 male-specific lethal 3 homolog (Drosophila) 10.1325
NADK2 NAD kinase 2, mitochondrial 10.1233
DEPDC5 DEP domain containing 5 10.074
PRAMEF11 PRAME family member 11 9.94988
STK11IP serine/threonine kinase 11 interacting protein 9.79091
PTEN phosphatase and tensin homolog 9.53481
LCE3B late cornified envelope 3B 9.24674
TMEM161B transmembrane protein 161B 9.13331
TSC22D3 TSC22 domain family, member 3 8.99141
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 8.8351
LAPTM5 lysosomal protein transmembrane 5 8.70103
SFXN1 sideroflexin 1 8.31723
TFEB transcription factor EB 8.30437
NDRG3 NDRG family member 3 8.16401
CYB561A3 cytochrome b561 family, member A3 8.07226
DENND1A DENN/MADD domain containing 1A 7.97834
GAPVD1 GTPase activating protein and VPS9 domains 1 7.96885
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 7.92021
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 7.75414
USP11 ubiquitin specific peptidase 11 7.66071
PCGF5 polycomb group ring finger 5 7.51756
RAMP1 receptor (G protein-coupled) activity modifying protein 1 7.45032
PLCL2 phospholipase C-like 2 7.44026
ALG3 ALG3, alpha-1,3- mannosyltransferase 7.32539
ITSN2 intersectin 2 7.23836
SEC14L1 SEC14-like 1 (S. cerevisiae) 7.0951
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 7.09049
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 7.09047
GCLM glutamate-cysteine ligase, modifier subunit 7.0823
HDAC11 histone deacetylase 11 6.99709
BTK Bruton agammaglobulinemia tyrosine kinase 6.79895
RAB42 RAB42, member RAS oncogene family 6.7725
SLC38A1 solute carrier family 38, member 1 6.71394
USP21 ubiquitin specific peptidase 21 6.70047
GSS glutathione synthetase 6.65515
CSTB cystatin B (stefin B) 6.65392
ANKH ANKH inorganic pyrophosphate transport regulator 6.56441
WDR45B WD repeat domain 45B 6.48351
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 6.42927
BEND3 BEN domain containing 3 6.39613
MICU1 mitochondrial calcium uptake 1 6.36832
HIST1H3H histone cluster 1, H3h 6.32903
ZFYVE26 zinc finger, FYVE domain containing 26 6.31874
ESPN espin 6.29197
AP5M1 adaptor-related protein complex 5, mu 1 subunit 6.28693
ZNF133 zinc finger protein 133 6.15968
ZNF251 zinc finger protein 251 6.13969
UVSSA UV-stimulated scaffold protein A 6.1235
HIST1H3B histone cluster 1, H3b 6.0965
MFSD12 major facilitator superfamily domain containing 12 6.02151
ALG9 ALG9, alpha-1,2-mannosyltransferase 6.01537
FOXO1 forkhead box O1 5.99524
METTL13 methyltransferase like 13 5.98043
DMXL1 Dmx-like 1 5.95855
CELF3 CUGBP, Elav-like family member 3 5.94692
DENND4A DENN/MADD domain containing 4A 5.94097
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 5.93642
GDI2 GDP dissociation inhibitor 2 5.92998
MEF2B myocyte enhancer factor 2B 5.80335
LCE3D late cornified envelope 3D 5.77139
RHOH ras homolog family member H 5.66432
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 5.66379
AP5B1 adaptor-related protein complex 5, beta 1 subunit 5.65308
BLNK B-cell linker 5.58561
FBXW2 F-box and WD repeat domain containing 2 5.57231
PAX5 paired box 5 5.553
SLC12A9 solute carrier family 12, member 9 5.55176
SIAH3 siah E3 ubiquitin protein ligase family member 3 5.48176
CUL7 cullin 7 5.45133
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 5.41412
PCDH20 protocadherin 20 5.38781
WWP2 WW domain containing E3 ubiquitin protein ligase 2 5.3878
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 5.31453
FAM167A family with sequence similarity 167, member A 5.29335
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 5.29285
CLCN3 chloride channel, voltage-sensitive 3 5.28035
TCF3 transcription factor 3 5.25297
SZT2 seizure threshold 2 homolog (mouse) 5.22412
DOCK2 dedicator of cytokinesis 2 5.22266
ARHGAP45 Rho GTPase activating protein 45 5.19526
ELOVL1 ELOVL fatty acid elongase 1 5.14293
AGFG1 ArfGAP with FG repeats 1 5.12472
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 5.11487
CD3E CD3e molecule, epsilon (CD3-TCR complex) 5.11473
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 5.10466
TMEM98 transmembrane protein 98 5.06014
WDR91 WD repeat domain 91 5.05378
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 5.04822
SPG11 spastic paraplegia 11 (autosomal recessive) 5.04449
ZNF80 zinc finger protein 80 4.99919
RAD50 RAD50 homolog (S. cerevisiae) 4.96171
SENP1 SUMO1/sentrin specific peptidase 1 4.93432
LDB3 LIM domain binding 3 4.92027
LDLRAP1 low density lipoprotein receptor adaptor protein 1 4.91618
AZIN1 antizyme inhibitor 1 4.91347
ZNF592 zinc finger protein 592 4.907
POU2AF1 POU class 2 associating factor 1 4.8748
CUEDC1 CUE domain containing 1 4.84708
CSNK2A1 casein kinase 2, alpha 1 polypeptide 4.75661
EPO erythropoietin 4.75082
FBN1 fibrillin 1 4.70299
BLVRA biliverdin reductase A 4.69803
BCO1 beta-carotene oxygenase 1 4.69583
ERCC8 excision repair cross-complementation group 8 4.68586
KL klotho 4.68481
EBF1 early B-cell factor 1 4.68017
CABP1 calcium binding protein 1 4.63238
RING1 ring finger protein 1 4.61994
GCLC glutamate-cysteine ligase, catalytic subunit 4.58591
PTRH2 peptidyl-tRNA hydrolase 2 4.55538
ANKFY1 ankyrin repeat and FYVE domain containing 1 4.53849
PMEL premelanosome protein 4.47205
S100A8 S100 calcium binding protein A8 4.47085
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 4.46782
FANK1 fibronectin type III and ankyrin repeat domains 1 4.46631
KCTD9 potassium channel tetramerization domain containing 9 4.46616
PRAMEF1 PRAME family member 1 4.45211
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 4.44945
MUC17 mucin 17, cell surface associated 4.41379
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 4.38192
ALG12 ALG12, alpha-1,6-mannosyltransferase 4.37588
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 4.36527
BAG4 BCL2-associated athanogene 4 4.34328
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 4.29414
HGFAC HGF activator 4.2927
PRDX6 peroxiredoxin 6 4.27502
HOMER2 homer scaffolding protein 2 4.26715
NPC1 Niemann-Pick disease, type C1 4.25464
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 4.24588
ELF1 E74-like factor 1 (ets domain transcription factor) 4.2222
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 4.22023
SH3GL1 SH3-domain GRB2-like 1 4.21372
WIPF1 WAS/WASL interacting protein family, member 1 4.21332
GABPB2 GA binding protein transcription factor, beta subunit 2 4.1989
LZIC leucine zipper and CTNNBIP1 domain containing 4.18719
HEATR5B HEAT repeat containing 5B 4.15359
MAF1 MAF1 homolog (S. cerevisiae) 4.14446
CDK5 cyclin-dependent kinase 5 4.13951
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 4.13171
MNT MAX network transcriptional repressor 4.1101
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) 4.10978
MED13 mediator complex subunit 13 4.10351
ACOT12 acyl-CoA thioesterase 12 4.08496
TMED8 transmembrane emp24 protein transport domain containing 8 4.07651
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 4.04219
LAMB1 laminin, beta 1 4.03198
NMUR2 neuromedin U receptor 2 4.03141
SCARB1 scavenger receptor class B, member 1 4.02631
S100A11 S100 calcium binding protein A11 4.01504
TGIF2 TGFB-induced factor homeobox 2 3.96853
KRTAP13-1 keratin associated protein 13-1 3.96844
NOSIP nitric oxide synthase interacting protein 3.95088
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 3.94462
ZDHHC19 zinc finger, DHHC-type containing 19 3.93286
PTN pleiotrophin 3.93005
TREM2 triggering receptor expressed on myeloid cells 2 3.92491
ERCC6 excision repair cross-complementation group 6 3.92181
EPHA1 EPH receptor A1 3.91687
SCAF4 SR-related CTD-associated factor 4 3.906
CPLX1 complexin 1 3.9035
THBS4 thrombospondin 4 3.8914
AP1B1 adaptor-related protein complex 1, beta 1 subunit 3.88748
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 3.88448
SLC25A30 solute carrier family 25, member 30 3.88275
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 3.87197
PDCD10 programmed cell death 10 3.8708
TCEA1 transcription elongation factor A (SII), 1 3.86994
ERCC1 excision repair cross-complementation group 1 3.8651
UCN2 urocortin 2 3.86348
TMEM200B transmembrane protein 200B 3.85984
SRD5A3 steroid 5 alpha-reductase 3 3.8569
ZBTB21 zinc finger and BTB domain containing 21 3.85019
VPS26C VPS26 endosomal protein sorting factor C 3.83265
RER1 retention in endoplasmic reticulum sorting receptor 1 3.8322
PON1 paraoxonase 1 3.83173
ELMO1 engulfment and cell motility 1 3.83028
IRF4 interferon regulatory factor 4 3.80877
EXOC3L4 exocyst complex component 3-like 4 3.79692
APOD apolipoprotein D 3.79492
WASHC3 WASH complex subunit 3 3.7886
SNX29 sorting nexin 29 3.78781
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 3.76131
ECM1 extracellular matrix protein 1 3.74529
EXOC7 exocyst complex component 7 3.73045
NCK1 NCK adaptor protein 1 3.67989
SLC26A11 solute carrier family 26 (anion exchanger), member 11 3.67298
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 3.66498
PTPN21 protein tyrosine phosphatase, non-receptor type 21 3.65858
NUP37 nucleoporin 37kDa 3.65761
RAB14 RAB14, member RAS oncogene family 3.64119
API5 apoptosis inhibitor 5 3.63165
IFNA17 interferon, alpha 17 3.58626
CD79A CD79a molecule, immunoglobulin-associated alpha 3.57543
CCNF cyclin F 3.57411
ACSL4 acyl-CoA synthetase long-chain family member 4 3.56545
ARL8B ADP-ribosylation factor-like 8B 3.56243
SPATA32 spermatogenesis associated 32 3.55634
SPDYE4 speedy/RINGO cell cycle regulator family member E4 3.55379
C1QL2 complement component 1, q subcomponent-like 2 3.55231
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 3.54893
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 3.53705
DRD4 dopamine receptor D4 3.5353
HIST1H2AA histone cluster 1, H2aa 3.53197
UNC79 unc-79 homolog (C. elegans) 3.53152
AHDC1 AT hook, DNA binding motif, containing 1 3.51246
CHD1L chromodomain helicase DNA binding protein 1-like 3.50238
TRIM40 tripartite motif containing 40 3.50176
MOGS mannosyl-oligosaccharide glucosidase 3.49965
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 3.49908
CABIN1 calcineurin binding protein 1 3.49879
USP34 ubiquitin specific peptidase 34 3.47615
GLIS2 GLIS family zinc finger 2 3.46304
OR51V1 olfactory receptor, family 51, subfamily V, member 1 3.4602
ITGAD integrin, alpha D 3.44867
C12ORF66 chromosome 12 open reading frame 66 3.42782
POU3F1 POU class 3 homeobox 1 3.42568
UBE2J1 ubiquitin-conjugating enzyme E2, J1 3.42369
VWA1 von Willebrand factor A domain containing 1 3.41347
CTBP1 C-terminal binding protein 1 3.3948
AP3B1 adaptor-related protein complex 3, beta 1 subunit 3.39197
MATN3 matrilin 3 3.38588
CCM2 cerebral cavernous malformation 2 3.37654
SUCLG1 succinate-CoA ligase, alpha subunit 3.37458
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 3.36043
DOT1L DOT1-like histone H3K79 methyltransferase 3.34739
ZBTB44 zinc finger and BTB domain containing 44 3.33465
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 3.33233
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 3.3222
UROS uroporphyrinogen III synthase 3.31258
TRIM33 tripartite motif containing 33 3.31213
AUH AU RNA binding protein/enoyl-CoA hydratase 3.30558
TKTL1 transketolase-like 1 3.30311
RAB5C RAB5C, member RAS oncogene family 3.30302
CHST10 carbohydrate sulfotransferase 10 3.29408
C1QTNF2 C1q and tumor necrosis factor related protein 2 3.29349
AP1M1 adaptor-related protein complex 1, mu 1 subunit 3.29015
PRSS50 protease, serine, 50 3.28783
COMMD3 COMM domain containing 3 3.2872
PRG3 proteoglycan 3 3.2865
PAN2 PAN2 poly(A) specific ribonuclease subunit 3.28309
GLUL glutamate-ammonia ligase 3.28202
AKAP1 A kinase (PRKA) anchor protein 1 3.28182
FAM181A family with sequence similarity 181, member A 3.27251
ADCY9 adenylate cyclase 9 3.27001
SMR3A submaxillary gland androgen regulated protein 3A 3.26167
SPATC1 spermatogenesis and centriole associated 1 3.25433
OR8S1 olfactory receptor, family 8, subfamily S, member 1 3.253
SETD1B SET domain containing 1B 3.23701
XPR1 xenotropic and polytropic retrovirus receptor 1 3.237
ZNF629 zinc finger protein 629 3.23622
VPS35L VPS35 endosomal protein sorting factor like 3.23451
TMEM127 transmembrane protein 127 3.22004
SYK spleen tyrosine kinase 3.21168
KIDINS220 kinase D-interacting substrate, 220kDa 3.21038
ANO9 anoctamin 9 3.20697
OR8B12 olfactory receptor, family 8, subfamily B, member 12 3.20646
SLX4 SLX4 structure-specific endonuclease subunit 3.20578
ARHGAP23 Rho GTPase activating protein 23 3.19934
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 3.19852
ZMYM3 zinc finger, MYM-type 3 3.18604
CCNT1 cyclin T1 3.18435
KSR2 kinase suppressor of ras 2 3.18139
GLS glutaminase 3.17773
COL17A1 collagen, type XVII, alpha 1 3.17411
ASXL1 additional sex combs like transcriptional regulator 1 3.15899
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 3.15586
CORO7 coronin 7 3.14469
IQSEC2 IQ motif and Sec7 domain 2 3.14222
STXBP1 syntaxin binding protein 1 3.13946
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 3.13044
GP1BB glycoprotein Ib (platelet), beta polypeptide 3.12251
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 3.12065
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 3.11614
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 3.06814
GPC2 glypican 2 3.06491
CCDC93 coiled-coil domain containing 93 3.06213
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 3.0539
CCDC32 coiled-coil domain containing 32 3.04927
CLEC12A C-type lectin domain family 12, member A 3.03478
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 3.02927
KIAA1211L KIAA1211-like 3.01474
MPG N-methylpurine-DNA glycosylase 3.00878
RAB11A RAB11A, member RAS oncogene family 3.00864
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 2.99972
PRRC2C proline-rich coiled-coil 2C 2.99539
ADAMTSL4 ADAMTS-like 4 2.98803
WDR4 WD repeat domain 4 2.97855
AUP1 ancient ubiquitous protein 1 2.97316
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 2.96804
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 2.9678
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 2.96701
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 2.96298
TMEM192 transmembrane protein 192 2.95977
MBD6 methyl-CpG binding domain protein 6 2.95819
MYB v-myb avian myeloblastosis viral oncogene homolog 2.94973
ZNF589 zinc finger protein 589 2.94861
FH fumarate hydratase 2.94638
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 2.9446
TTC7A tetratricopeptide repeat domain 7A 2.94426
MTCH2 mitochondrial carrier 2 2.94278
PPP1R26 protein phosphatase 1, regulatory subunit 26 2.94059
COMP cartilage oligomeric matrix protein 2.93769
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 2.93419
MRPL52 mitochondrial ribosomal protein L52 2.93105
ADSS1 adenylosuccinate synthase 1 2.92586
PRRT3 proline-rich transmembrane protein 3 2.92531
LSP1 lymphocyte-specific protein 1 2.92312
MBNL1 muscleblind-like splicing regulator 1 2.92179
HHLA2 HERV-H LTR-associating 2 2.92133
FEM1A fem-1 homolog a (C. elegans) 2.91346
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.9107
CLMN calmin (calponin-like, transmembrane) 2.90732
RC3H1 ring finger and CCCH-type domains 1 2.90726
MROH6 maestro heat-like repeat family member 6 2.90491
KLHL14 kelch-like family member 14 2.8931
ZNF135 zinc finger protein 135 2.89031
TBX6 T-box 6 2.87699
MYPN myopalladin 2.8724
PPCDC phosphopantothenoylcysteine decarboxylase 2.86865
ATAD5 ATPase family, AAA domain containing 5 2.86061
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 2.85738
GFM2 G elongation factor, mitochondrial 2 2.85716
RORC RAR-related orphan receptor C 2.85455
ARID5A AT rich interactive domain 5A (MRF1-like) 2.85292
TMSB15A thymosin beta 15a 2.85103
CAPRIN1 cell cycle associated protein 1 2.83773
DERL1 derlin 1 2.83772
CDIP1 cell death-inducing p53 target 1 2.82989
AUTS2 autism susceptibility candidate 2 2.82767
AK2 adenylate kinase 2 2.82642
EIPR1 EARP complex and GARP complex interacting protein 1 2.82632
ALG6 ALG6, alpha-1,3-glucosyltransferase 2.82536
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.82512
ERCC4 excision repair cross-complementation group 4 2.82086
WASHC4 WASH complex subunit 4 2.8187
PIPOX pipecolic acid oxidase 2.80747
HSF4 heat shock transcription factor 4 2.80602
PRSS57 protease, serine, 57 2.80529
RAB35 RAB35, member RAS oncogene family 2.80244
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.7989
FLYWCH2 FLYWCH family member 2 2.79808
ARMCX6 armadillo repeat containing, X-linked 6 2.79723
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 2.79542
PRAMEF20 PRAME family member 20 2.78787
TSC1 tuberous sclerosis 1 2.77993
EFNB3 ephrin-B3 2.77988
CCDC47 coiled-coil domain containing 47 2.77392
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 2.76869
PTPRF protein tyrosine phosphatase, receptor type, F 2.76742
NBPF3 neuroblastoma breakpoint family, member 3 2.76528
KAT7 K(lysine) acetyltransferase 7 2.76251
NINJ2 ninjurin 2 2.76082
OR52E4 olfactory receptor, family 52, subfamily E, member 4 2.75782
CHID1 chitinase domain containing 1 2.75486
LYPLA2 lysophospholipase II 2.74087
PPCS phosphopantothenoylcysteine synthetase 2.73902
CFC1 cripto, FRL-1, cryptic family 1 2.73189
PRR9 proline rich 9 2.73113
EIF4E2 eukaryotic translation initiation factor 4E family member 2 2.73076
PGLYRP3 peptidoglycan recognition protein 3 2.73051
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.72746
WDR37 WD repeat domain 37 2.72603
ERP29 endoplasmic reticulum protein 29 2.72508
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.72236
DIXDC1 DIX domain containing 1 2.71613
RBM38 RNA binding motif protein 38 2.70631
HCCS holocytochrome c synthase 2.69413
RPL22L1 ribosomal protein L22-like 1 2.69413
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 2.69314
CTRB2 chymotrypsinogen B2 2.69181
KDM4A lysine (K)-specific demethylase 4A 2.69067
SLCO4C1 solute carrier organic anion transporter family, member 4C1 2.69047
CCL7 chemokine (C-C motif) ligand 7 2.69029
HDAC5 histone deacetylase 5 2.68019
DPH6 diphthamine biosynthesis 6 2.67729
TRIM28 tripartite motif containing 28 2.67414
CIDEC cell death-inducing DFFA-like effector c 2.6726
OXSM 3-oxoacyl-ACP synthase, mitochondrial 2.67248
MPDU1 mannose-P-dolichol utilization defect 1 2.66594
TPM2 tropomyosin 2 (beta) 2.66469
SPOCD1 SPOC domain containing 1 2.66386
UBE2G2 ubiquitin-conjugating enzyme E2G 2 2.6622
RIF1 replication timing regulatory factor 1 2.66134
CFAP410 cilia and flagella associated protein 410 2.65995
NTN4 netrin 4 2.65771
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 2.65711
TMEM40 transmembrane protein 40 2.65592
PRR30 proline rich 30 2.64381
MIER3 mesoderm induction early response 1, family member 3 2.64018
PDCL2 phosducin-like 2 2.63767
LCE3E late cornified envelope 3E 2.63696
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.63504
OR5B3 olfactory receptor, family 5, subfamily B, member 3 2.63502
SEZ6 seizure related 6 homolog (mouse) 2.62795
AFF1 AF4/FMR2 family, member 1 2.62199
LIMD1 LIM domains containing 1 2.62175
TGFBR1 transforming growth factor, beta receptor 1 2.61953
GPSM3 G-protein signaling modulator 3 2.61516
RBP3 retinol binding protein 3, interstitial 2.60857
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 2.6076
IFITM2 interferon induced transmembrane protein 2 2.60616
SEPTIN14 septin 14 2.606
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 2.60541
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 2.59845
ARL11 ADP-ribosylation factor-like 11 2.5967
FLG filaggrin 2.58886
GUCA1B guanylate cyclase activator 1B (retina) 2.58384
CCND3 cyclin D3 2.58149
ZER1 zyg-11 related, cell cycle regulator 2.58041
KIAA0513 KIAA0513 2.57941
CORO1A coronin, actin binding protein, 1A 2.57508
DCPS decapping enzyme, scavenger 2.56478
CD79B CD79b molecule, immunoglobulin-associated beta 2.56384
EPN1 epsin 1 2.56212
ARSI arylsulfatase family, member I 2.5577
CIB4 calcium and integrin binding family member 4 2.55596
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.55351
ARID3B AT rich interactive domain 3B (BRIGHT-like) 2.5503
BAG2 BCL2-associated athanogene 2 2.54248
NPC1L1 NPC1-like 1 2.54055
FIZ1 FLT3-interacting zinc finger 1 2.53936
KRTAP9-8 keratin associated protein 9-8 2.53859
EPHA2 EPH receptor A2 2.5357
GUCY2C guanylate cyclase 2C 2.5311
UGP2 UDP-glucose pyrophosphorylase 2 2.52779
ATAD3B ATPase family, AAA domain containing 3B 2.52762
GTF2I general transcription factor IIi 2.5235
PDZK1IP1 PDZK1 interacting protein 1 2.52325
ZNF460 zinc finger protein 460 2.52233
PASK PAS domain containing serine/threonine kinase 2.5187
YJEFN3 YjeF N-terminal domain containing 3 2.51597
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.51538
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 2.51535
UVRAG UV radiation resistance associated 2.51041
MANF mesencephalic astrocyte-derived neurotrophic factor 2.51009
TMEM131L transmembrane 131 like 2.50628
TMEM147 transmembrane protein 147 2.5032
MRPL11 mitochondrial ribosomal protein L11 2.50288
TRAFD1 TRAF-type zinc finger domain containing 1 2.50165
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 2.50109
H1FNT H1 histone family, member N, testis-specific 2.50002
CAB39 calcium binding protein 39 2.49839
GOLT1B golgi transport 1B 2.49024
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.49002
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.48654
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 2.48567
HTT huntingtin 2.48522
ADGRB2 adhesion G protein-coupled receptor B2 2.48206
CYTH3 cytohesin 3 2.47992
IGFBP7 insulin-like growth factor binding protein 7 2.47788
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 2.47729
FLG2 filaggrin family member 2 2.4744
ORC2 origin recognition complex, subunit 2 2.46085
REXO2 RNA exonuclease 2 2.45864
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 2.45684
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 2.45187
FBXL19 F-box and leucine-rich repeat protein 19 2.45012
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) 2.44665
CYBA cytochrome b-245, alpha polypeptide 2.44275
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.43571
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 2.42611
FETUB fetuin B 2.42586
DERL2 derlin 2 2.42525
TEX29 testis expressed 29 2.41621
DIO3 deiodinase, iodothyronine, type III 2.41026
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 2.40829
DPH2 DPH2 homolog (S. cerevisiae) 2.4054
MEAK7 MTOR associated protein, eak-7 homolog 2.39323
HDAC8 histone deacetylase 8 2.38846
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 2.38375
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 2.38062
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 2.37874
KRT13 keratin 13, type I 2.36483
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 2.36388
CNOT11 CCR4-NOT transcription complex, subunit 11 2.36351
RIMKLB ribosomal modification protein rimK-like family member B 2.36043
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 2.36027
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 2.3587
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 2.35071
SAG S-antigen; retina and pineal gland (arrestin) 2.34636
BRPF1 bromodomain and PHD finger containing, 1 2.34311
NHLH1 nescient helix loop helix 1 2.34295
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 2.33834
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.33781
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.33747
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.33534
LMO4 LIM domain only 4 2.3332
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.3323
RABIF RAB interacting factor 2.32907
MAGEB2 melanoma antigen family B2 2.32551
FRG2C FSHD region gene 2 family, member C 2.31661
BRD1 bromodomain containing 1 2.31327
DPPA5 developmental pluripotency associated 5 2.31296
SIVA1 SIVA1, apoptosis-inducing factor 2.31252
FRMD7 FERM domain containing 7 2.31197
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.31064
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.31054
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.30602
PIFO primary cilia formation 2.30456
ETV7 ets variant 7 2.29445
TIPE2 TNF alpha induced protein 8 like 2 2.29362
CRACD capping protein inhibiting regulator of actin dynamics 2.2935
GTF2IRD1 GTF2I repeat domain containing 1 2.29226
CXCR3 chemokine (C-X-C motif) receptor 3 2.29061
COL15A1 collagen, type XV, alpha 1 2.28912
CPQ carboxypeptidase Q 2.28885
LCE1B late cornified envelope 1B 2.28851
ZNF12 zinc finger protein 12 2.28819
MXRA7 matrix-remodelling associated 7 2.28581
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 2.28503
ATF5 activating transcription factor 5 2.27826
FAM3A family with sequence similarity 3, member A 2.277
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2.27682
VENTX VENT homeobox 2.27595
DPH1 diphthamide biosynthesis 1 2.27491
PMM2 phosphomannomutase 2 2.27434
ATXN2L ataxin 2-like 2.27094
CEND1 cell cycle exit and neuronal differentiation 1 2.26804
EVPL envoplakin 2.26458
DPH5 diphthamide biosynthesis 5 2.2554
TADA1 transcriptional adaptor 1 2.24606
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2.23737
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 2.23125
SDHAF1 succinate dehydrogenase complex assembly factor 1 2.22742
TOMM70 translocase of outer mitochondrial membrane 70 2.22408
MPP1 membrane protein, palmitoylated 1, 55kDa 2.2216
FANCD2 Fanconi anemia, complementation group D2 2.21953
ZNF142 zinc finger protein 142 2.21664
KMT2B lysine (K)-specific methyltransferase 2B 2.21418
ZNF479 zinc finger protein 479 2.21104
SACK1G scaffolding CK1 anchoring protein G 2.20387
RNASEH2A ribonuclease H2, subunit A 2.20095
CMIP c-Maf inducing protein 2.19936
C19ORF67 chromosome 19 open reading frame 67 2.19482
CCL27 chemokine (C-C motif) ligand 27 2.19242
TALDO1 transaldolase 1 2.19068
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 2.18472
PIEZO1 piezo-type mechanosensitive ion channel component 1 2.1821
SPATC1L spermatogenesis and centriole associated 1-like 2.17821
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 2.17714
RTN4RL1 reticulon 4 receptor-like 1 2.1747
FBXO22 F-box protein 22 2.17368
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 2.17358
SYNGR4 synaptogyrin 4 2.17282
WASHC5 WASH complex subunit 5 2.17189
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 2.16851
PLIN4 perilipin 4 2.16842
C2CD4A C2 calcium-dependent domain containing 4A 2.16774
SPATA33 spermatogenesis associated 33 2.16208
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 2.16028
RPIA ribose 5-phosphate isomerase A 2.15702
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 2.14901
MPV17 MpV17 mitochondrial inner membrane protein 2.14729
SRM spermidine synthase 2.14497
SMS spermine synthase 2.14456
ARSF arylsulfatase F 2.13654
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 2.13591
CHD8 chromodomain helicase DNA binding protein 8 2.13319
HEXIM2 hexamethylene bis-acetamide inducible 2 2.13263
ATP7A ATPase, Cu++ transporting, alpha polypeptide 2.13153
PEX10 peroxisomal biogenesis factor 10 2.13087
FLAD1 flavin adenine dinucleotide synthetase 1 2.13067
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 2.1274
C1ORF50 chromosome 1 open reading frame 50 2.12573
MRPL2 mitochondrial ribosomal protein L2 2.12526
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 2.12496
MAP7D1 MAP7 domain containing 1 2.1213
FCHO1 FCH domain only 1 2.12097
CEP55 centrosomal protein 55kDa 2.12004
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.11791
PIAS1 protein inhibitor of activated STAT, 1 2.11722
HK2 hexokinase 2 2.11555
DRD2 dopamine receptor D2 2.11529
CERS1 ceramide synthase 1 2.11492
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 2.11148
LTBP3 latent transforming growth factor beta binding protein 3 2.11146
SDHAF2 succinate dehydrogenase complex assembly factor 2 2.11054
C17ORF53 chromosome 17 open reading frame 53 2.11044
LIPT1 lipoyltransferase 1 2.10803
UBE2E1 ubiquitin-conjugating enzyme E2E 1 2.10773
MECR mitochondrial trans-2-enoyl-CoA reductase 2.10676
MRPS33 mitochondrial ribosomal protein S33 2.10566
IQCE IQ motif containing E 2.10369
PMVK phosphomevalonate kinase 2.1027
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 2.10234
HDC histidine decarboxylase 2.10115
LIN37 lin-37 DREAM MuvB core complex component 2.09888
SHANK1 SH3 and multiple ankyrin repeat domains 1 2.09881
MRPL42 mitochondrial ribosomal protein L42 2.09792
TSC2 tuberous sclerosis 2 2.09678
NSRP1 nuclear speckle splicing regulatory protein 1 2.09571
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.09462
LAGE3 L antigen family, member 3 2.09222
COMMD7 COMM domain containing 7 2.0897
SOCS5 suppressor of cytokine signaling 5 2.0872
SPRR3 small proline-rich protein 3 2.08637
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.08223
DCAF15 DDB1 and CUL4 associated factor 15 2.08054
COX14 COX14 cytochrome c oxidase assembly factor 2.0801
SHD Src homology 2 domain containing transforming protein D 2.07969
SSX1 synovial sarcoma, X breakpoint 1 2.07507
PTDSS1 phosphatidylserine synthase 1 2.07301
THAP3 THAP domain containing, apoptosis associated protein 3 2.0724
UNC119 unc-119 homolog (C. elegans) 2.07143
PRSS1 protease, serine, 1 (trypsin 1) 2.07041
RASL10A RAS-like, family 10, member A 2.07021
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 2.06665
KLF13 Kruppel-like factor 13 2.06153
SFTPD surfactant protein D 2.06102
STAG2 stromal antigen 2 2.06097
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 2.06048
CDR2 cerebellar degeneration-related protein 2, 62kDa 2.05904
ISCA1 iron-sulfur cluster assembly 1 2.05435
UBALD1 UBA-like domain containing 1 2.0492
ZNF19 zinc finger protein 19 2.04898
DISP2 dispatched homolog 2 (Drosophila) 2.04833
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.04556
NOA1 nitric oxide associated 1 2.0381
DEF8 differentially expressed in FDCP 8 homolog (mouse) 2.03792
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.03747
BOLA1 bolA family member 1 2.03548
BAG6 BCL2-associated athanogene 6 2.03265
HEXD hexosaminidase D 2.03041
CD40LG CD40 ligand 2.02979
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.0266
LRRC15 leucine rich repeat containing 15 2.02513
SCLY selenocysteine lyase 2.02481
KDSR 3-ketodihydrosphingosine reductase 2.02337
SLC44A4 solute carrier family 44, member 4 2.02288
DAPK3 death-associated protein kinase 3 2.02164
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 2.01749
SHB Src homology 2 domain containing adaptor protein B 2.01436
USP45 ubiquitin specific peptidase 45 2.01305
ZNF683 zinc finger protein 683 2.0099
TUFM Tu translation elongation factor, mitochondrial 2.00892
MEN1 multiple endocrine neoplasia I 2.00891
OR4C6 olfactory receptor, family 4, subfamily C, member 6 2.00889
C15ORF41 chromosome 15 open reading frame 41 2.00645
MATR3 matrin 3 2.00379
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 2.00072