STAT1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description signal transducer and activator of transcription 1, 91kDa|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6772)
External Link https://ncbi.nlm.nih.gov/gene/6772
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Genes

499 genes differentially expressed following the STAT1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 0.0192732
MAP7 microtubule-associated protein 7 0.0169442
SEPP1 selenoprotein P, plasma, 1 0.0160486
NUSAP1 nucleolar and spindle associated protein 1 0.0159958
S100A9 S100 calcium binding protein A9 0.0157442
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.015629
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0142724
AEBP1 AE binding protein 1 0.0135648
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0134685
COMP cartilage oligomeric matrix protein 0.0128892
SDC2 syndecan 2 0.012791
HMGB2 high mobility group box 2 0.0127193
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.0126745
SMC1A structural maintenance of chromosomes 1A 0.0126401
COL6A2 collagen, type VI, alpha 2 0.0120792
FASN fatty acid synthase 0.0117358
CALD1 caldesmon 1 0.0117053
GJA1 gap junction protein, alpha 1, 43kDa 0.0114466
CTSK cathepsin K 0.0114114
SPON2 spondin 2, extracellular matrix protein 0.0112569
DCK deoxycytidine kinase 0.0111537
FBLN1 fibulin 1 0.0110493
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.0108606
HOPX HOP homeobox 0.010637
ADIRF adipogenesis regulatory factor 0.0105923
SPARCL1 SPARC-like 1 (hevin) 0.0104856
COLEC12 collectin sub-family member 12 0.0103753
GPX3 glutathione peroxidase 3 0.0102997
VCAM1 vascular cell adhesion molecule 1 0.0102393
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.0101573
TSPAN4 tetraspanin 4 0.0101495
FGFR3 fibroblast growth factor receptor 3 0.0100763
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00994501
CD14 CD14 molecule 0.00991962
GLUL glutamate-ammonia ligase 0.00986514
TMEM14B transmembrane protein 14B 0.0097134
INSIG1 insulin induced gene 1 0.00963991
NPTX2 neuronal pentraxin II 0.00961548
ISYNA1 inositol-3-phosphate synthase 1 0.00953833
TGFB3 transforming growth factor, beta 3 0.00945088
DYNLT1 dynein, light chain, Tctex-type 1 0.00937393
CD99 CD99 molecule 0.00933066
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.00929815
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00918231
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00906694
IGFBP1 insulin-like growth factor binding protein 1 0.00905363
LYZ lysozyme 0.00904483
TMEM176B transmembrane protein 176B 0.00897072
CD300A CD300a molecule 0.00895741
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00888123
CPE carboxypeptidase E 0.00886352
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00885463
SPON1 spondin 1, extracellular matrix protein 0.0088254
TYROBP TYRO protein tyrosine kinase binding protein 0.00881363
HMGB3 high mobility group box 3 0.00881328
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.0088115
CLEC2B C-type lectin domain family 2, member B 0.00880624
CEL carboxyl ester lipase 0.00877124
RIN2 Ras and Rab interactor 2 0.0087456
COL6A1 collagen, type VI, alpha 1 0.00872952
PLK1 polo-like kinase 1 0.00872147
CRYL1 crystallin, lambda 1 0.00862108
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00860638
ASPN asporin 0.00860334
TIMP3 TIMP metallopeptidase inhibitor 3 0.00858603
GLOD4 glyoxalase domain containing 4 0.00856599
MMP9 matrix metallopeptidase 9 0.00853662
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00849478
PLN phospholamban 0.00848368
AKAP7 A kinase (PRKA) anchor protein 7 0.00845816
RAPSN receptor-associated protein of the synapse 0.0084523
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00843902
DAPK1 death-associated protein kinase 1 0.00841862
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00833814
FRZB frizzled-related protein 0.00833105
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00832539
RGS5 regulator of G-protein signaling 5 0.0083058
NNMT nicotinamide N-methyltransferase 0.00825047
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00820737
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00820075
PERP PERP, TP53 apoptosis effector 0.00816659
GRAMD4 GRAM domain containing 4 0.00816304
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.00815114
CD320 CD320 molecule 0.00812832
NUP54 nucleoporin 54kDa 0.00812474
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00811191
LPAR1 lysophosphatidic acid receptor 1 0.00810962
COL6A3 collagen, type VI, alpha 3 0.00809347
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00808513
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.008077
LPAR6 lysophosphatidic acid receptor 6 0.00806952
LST1 leukocyte specific transcript 1 0.00801103
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00797367
RACGAP1 Rac GTPase activating protein 1 0.00796722
DCXR dicarbonyl/L-xylulose reductase 0.00795751
ANXA4 annexin A4 0.00794764
F13A1 coagulation factor XIII, A1 polypeptide 0.0079252
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00785421
PRDX4 peroxiredoxin 4 0.00785184
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00782048
TNS3 tensin 3 0.00778065
TXLNA taxilin alpha 0.00777753
FUCA1 fucosidase, alpha-L- 1, tissue 0.00777435
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.0077577
NMU neuromedin U 0.00773987
TBC1D16 TBC1 domain family, member 16 0.0077264
APMAP adipocyte plasma membrane associated protein 0.00766945
MCF2L MCF.2 cell line derived transforming sequence-like 0.00766544
LRRC15 leucine rich repeat containing 15 0.00762218
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.0076219
SDC1 syndecan 1 0.0076173
COPS7A COP9 signalosome subunit 7A 0.00757718
TYMS thymidylate synthetase 0.00756092
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00754689
PDGFA platelet-derived growth factor alpha polypeptide 0.00751797
C1R complement component 1, r subcomponent 0.00740952
PDGFD platelet derived growth factor D 0.00740112
BLNK B-cell linker 0.00739408
CEP43 centrosomal protein 43 0.00737553
FAM149A family with sequence similarity 149, member A 0.00734276
TMEM106C transmembrane protein 106C 0.00732411
CSTA cystatin A (stefin A) 0.00730688
RAB20 RAB20, member RAS oncogene family 0.00729755
DCN decorin 0.00729172
RAB40B RAB40B, member RAS oncogene family 0.00724323
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00722404
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00718176
BAD BCL2-associated agonist of cell death 0.00717186
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.00716974
PDLIM3 PDZ and LIM domain 3 0.00716317
PI3 peptidase inhibitor 3, skin-derived 0.0071537
CLEC7A C-type lectin domain family 7, member A 0.00714456
CPT1A carnitine palmitoyltransferase 1A (liver) 0.00712919
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00709128
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.00705743
AMBP alpha-1-microglobulin/bikunin precursor 0.00705006
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00702176
FAIM Fas apoptotic inhibitory molecule 0.00701949
RNASE6 ribonuclease, RNase A family, k6 0.00701399
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00698741
EVL Enah/Vasp-like 0.0069871
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.00698459
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 0.00696289
LGALS2 lectin, galactoside-binding, soluble, 2 0.00696118
PLXNC1 plexin C1 0.0069391
NELL1 NEL-like 1 (chicken) 0.00692516
WTAP Wilms tumor 1 associated protein 0.0069247
ATF1 activating transcription factor 1 0.00692378
GPNMB glycoprotein (transmembrane) nmb 0.00690659
SORBS1 sorbin and SH3 domain containing 1 0.00690574
HMGB1 high mobility group box 1 0.00689215
BAG6 BCL2-associated athanogene 6 0.00689027
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00688953
WISP2 WNT1 inducible signaling pathway protein 2 0.00688607
CDK1 cyclin-dependent kinase 1 0.00685351
ESR1 estrogen receptor 1 0.00681533
CLEC10A C-type lectin domain family 10, member A 0.00681271
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.00678712
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00678258
CREBL2 cAMP responsive element binding protein-like 2 0.00678255
ALDOA aldolase A, fructose-bisphosphate 0.00677929
MAOA monoamine oxidase A 0.00677744
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00677557
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00677478
CLIC2 chloride intracellular channel 2 0.00676993
TMPO thymopoietin 0.00675672
ZSCAN31 zinc finger and SCAN domain containing 31 0.00675521
CLEC3B C-type lectin domain family 3, member B 0.0067435
TBCD tubulin folding cofactor D 0.00672717
APIP APAF1 interacting protein 0.00672587
MN1 meningioma (disrupted in balanced translocation) 1 0.00671516
ANGPTL2 angiopoietin-like 2 0.00669737
RAB25 RAB25, member RAS oncogene family 0.00668163
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00665755
HBB hemoglobin, beta 0.00664038
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00662629
FPR1 formyl peptide receptor 1 0.00662199
PROM1 prominin 1 0.00660108
PRRX1 paired related homeobox 1 0.00660015
IDO1 indoleamine 2,3-dioxygenase 1 0.00659603
RRM2 ribonucleotide reductase M2 0.00658191
HMGN5 high mobility group nucleosome binding domain 5 0.00657147
TBP TATA box binding protein 0.00655885
PANK3 pantothenate kinase 3 0.00655754
MREG melanoregulin 0.00653051
CA2 carbonic anhydrase II 0.00652698
PEX3 peroxisomal biogenesis factor 3 0.00649493
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00649221
KANK2 KN motif and ankyrin repeat domains 2 0.00649099
NUP43 nucleoporin 43kDa 0.00648189
LCN2 lipocalin 2 0.00645961
HDAC1 histone deacetylase 1 0.00645301
TDO2 tryptophan 2,3-dioxygenase 0.00644053
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.00643923
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.00643576
CFI complement factor I 0.00643551
PDGFRL platelet-derived growth factor receptor-like 0.00643421
UNC119B unc-119 homolog B (C. elegans) 0.00639076
ANPEP alanyl (membrane) aminopeptidase 0.00636823
EPYC epiphycan 0.00635929
CD34 CD34 molecule 0.00633983
IFNGR1 interferon gamma receptor 1 0.00633536
S100A2 S100 calcium binding protein A2 0.00632022
S100A7 S100 calcium binding protein A7 0.00631883
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.00631539
SKAP2 src kinase associated phosphoprotein 2 0.00631064
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.00630098
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00628901
ELP5 elongator acetyltransferase complex subunit 5 0.00628697
ST18 suppression of tumorigenicity 18, zinc finger 0.00627217
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00626408
ADAM9 ADAM metallopeptidase domain 9 0.00625403
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.00624558
BIRC5 baculoviral IAP repeat containing 5 0.00624401
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.0062417
NEMP1 nuclear envelope integral membrane protein 1 0.00624167
S100A12 S100 calcium binding protein A12 0.00623901
SLIT2 slit homolog 2 (Drosophila) 0.00623773
FBXO5 F-box protein 5 0.00622805
PEX2 peroxisomal biogenesis factor 2 0.00622696
MAT1A methionine adenosyltransferase I, alpha 0.00618978
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.00617776
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.0061777
TMEM70 transmembrane protein 70 0.00617194
C6 complement component 6 0.00617166
STON1 stonin 1 0.00617009
ENO1 enolase 1, (alpha) 0.00616651
RAD21 RAD21 homolog (S. pombe) 0.0061588
NEK4 NIMA-related kinase 4 0.00614831
TRAPPC2L trafficking protein particle complex 2-like 0.00614818
SNRPG small nuclear ribonucleoprotein polypeptide G 0.00614811
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00614274
LGALS4 lectin, galactoside-binding, soluble, 4 0.00614201
PAGE4 P antigen family, member 4 (prostate associated) 0.00614084
EML3 echinoderm microtubule associated protein like 3 0.00613374
CD209 CD209 molecule 0.00612909
TPSAB1 tryptase alpha/beta 1 0.00612838
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.00612365
MEA1 male-enhanced antigen 1 0.00612021
GRHL2 grainyhead-like 2 (Drosophila) 0.00611969
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.00611772
SLC38A1 solute carrier family 38, member 1 0.00609787
SEC23A Sec23 homolog A (S. cerevisiae) 0.0060969
KATNA1 katanin p60 (ATPase containing) subunit A 1 0.00609303
MYO5C myosin VC 0.00607988
TEX30 testis expressed 30 0.00607174
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00606885
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 0.006068
IL7R interleukin 7 receptor 0.00606256
CCNG2 cyclin G2 0.00604542

decreased expression

Symbol Name Standardized Value
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0251563
HSPA1A heat shock 70kDa protein 1A -0.0213799
MX1 MX dynamin-like GTPase 1 -0.0212868
IFI44L interferon-induced protein 44-like -0.01962
ISG15 ISG15 ubiquitin-like modifier -0.0188412
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0178709
IFI27 interferon, alpha-inducible protein 27 -0.0171608
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0142431
BAMBI BMP and activin membrane-bound inhibitor -0.0141658
CRYAB crystallin, alpha B -0.0139582
SFTPB surfactant protein B -0.0138638
KRT7 keratin 7, type II -0.013436
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0134102
ZMAT3 zinc finger, matrin-type 3 -0.0133192
IL32 interleukin 32 -0.0132626
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0130308
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0127668
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0125916
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.0125163
LMCD1 LIM and cysteine-rich domains 1 -0.0124607
TP53I3 tumor protein p53 inducible protein 3 -0.0122568
IFI44 interferon-induced protein 44 -0.0122433
WDR7 WD repeat domain 7 -0.0121856
MAMLD1 mastermind-like domain containing 1 -0.0121364
MAGEA3 melanoma antigen family A3 -0.0120183
ALCAM activated leukocyte cell adhesion molecule -0.0119987
LBH limb bud and heart development -0.0119768
IRF9 interferon regulatory factor 9 -0.0119578
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.0117146
IFI6 interferon, alpha-inducible protein 6 -0.0117053
CEMIP cell migration inducing protein, hyaluronan binding -0.0117004
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.0115452
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.0113497
TRIM22 tripartite motif containing 22 -0.0112121
MVP major vault protein -0.0110385
ABLIM1 actin binding LIM protein 1 -0.0110126
WIF1 WNT inhibitory factor 1 -0.010986
OXTR oxytocin receptor -0.0109386
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.0109066
PLIN2 perilipin 2 -0.0108896
ARL4A ADP-ribosylation factor-like 4A -0.0108813
ARMCX2 armadillo repeat containing, X-linked 2 -0.0108358
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0107995
FOLR1 folate receptor 1 (adult) -0.0105104
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.0105053
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.0105039
BST2 bone marrow stromal cell antigen 2 -0.0104884
COBL cordon-bleu WH2 repeat protein -0.0104487
PRSS21 protease, serine, 21 (testisin) -0.010427
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0104166
RBM34 RNA binding motif protein 34 -0.0103416
LRRN3 leucine rich repeat neuronal 3 -0.0102976
CHD7 chromodomain helicase DNA binding protein 7 -0.0101366
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.010086
MT1X metallothionein 1X -0.0100765
CADM1 cell adhesion molecule 1 -0.0100756
C8ORF4 chromosome 8 open reading frame 4 -0.0100744
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.0100584
TENT5A terminal nucleotidyltransferase 5A -0.0100505
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0100372
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00992554
TNNC1 troponin C type 1 (slow) -0.00981402
KLK11 kallikrein-related peptidase 11 -0.00978649
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0097297
NKX2-1 NK2 homeobox 1 -0.00967142
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00961569
ZNF91 zinc finger protein 91 -0.00957343
RTN2 reticulon 2 -0.00956256
PDLIM1 PDZ and LIM domain 1 -0.00955344
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00953271
SP100 SP100 nuclear antigen -0.00933756
OXA1L oxidase (cytochrome c) assembly 1-like -0.00929734
KLF6 Kruppel-like factor 6 -0.00924329
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00920978
RTCA RNA 3'-terminal phosphate cyclase -0.00918453
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00917473
SOX10 SRY (sex determining region Y)-box 10 -0.00913157
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00912164
GALC galactosylceramidase -0.0091199
ANXA1 annexin A1 -0.00909779
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00909578
MAGEA12 melanoma antigen family A12 -0.00907313
RND3 Rho family GTPase 3 -0.00906315
DLK1 delta-like 1 homolog (Drosophila) -0.00904417
PSAT1 phosphoserine aminotransferase 1 -0.00903933
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00901746
OPTN optineurin -0.00901663
RRAGD Ras-related GTP binding D -0.00900979
LAMP3 lysosomal-associated membrane protein 3 -0.00894215
CAPN3 calpain 3, (p94) -0.00893205
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00890182
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00886054
TGFBR3 transforming growth factor, beta receptor III -0.00885551
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00883393
KRT81 keratin 81, type II -0.00880922
ABAT 4-aminobutyrate aminotransferase -0.00876122
KRT14 keratin 14, type I -0.00867261
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00867083
MYBPC1 myosin binding protein C, slow type -0.00864395
MAL mal, T-cell differentiation protein -0.00863412
KLF5 Kruppel-like factor 5 (intestinal) -0.00862217
JUNB jun B proto-oncogene -0.00853755
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00851587
SGK1 serum/glucocorticoid regulated kinase 1 -0.00848921
ARMCX3 armadillo repeat containing, X-linked 3 -0.00848466
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.00845808
NRCAM neuronal cell adhesion molecule -0.008448
IFIH1 interferon induced with helicase C domain 1 -0.00842395
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00840613
HIST1H2BD histone cluster 1, H2bd -0.00839324
SNAP25 synaptosomal-associated protein, 25kDa -0.00837533
POPDC3 popeye domain containing 3 -0.00832071
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00831255
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00828587
SFTPA2 surfactant protein A2 -0.00826874
WARS1 tryptophanyl-tRNA synthetase 1 -0.00826543
PDE4B phosphodiesterase 4B, cAMP-specific -0.00823664
LAMC2 laminin, gamma 2 -0.00823471
BCL3 B-cell CLL/lymphoma 3 -0.00823307
ELMO1 engulfment and cell motility 1 -0.00819521
KLF7 Kruppel-like factor 7 (ubiquitous) -0.00819499
STATH statherin -0.00818897
IGFBP5 insulin-like growth factor binding protein 5 -0.00818281
PRKCA protein kinase C, alpha -0.00817086
AZU1 azurocidin 1 -0.00816856
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00816622
SP110 SP110 nuclear body protein -0.00814945
IL2RG interleukin 2 receptor, gamma -0.00814074
CALB1 calbindin 1, 28kDa -0.00813544
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0080958
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.0080401
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.00803854
PPARG peroxisome proliferator-activated receptor gamma -0.00803538
PTK2 protein tyrosine kinase 2 -0.00802033
TUBB6 tubulin, beta 6 class V -0.00800225
TMEM100 transmembrane protein 100 -0.00798894
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00796359
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.0079623
PON2 paraoxonase 2 -0.00795212
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00793909
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00793747
MT1HL1 metallothionein 1H-like 1 -0.0079137
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00789746
ADGRL2 adhesion G protein-coupled receptor L2 -0.00789112
PADI2 peptidyl arginine deiminase, type II -0.00789091
PDZK1IP1 PDZK1 interacting protein 1 -0.00787149
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00785488
GUCY2C guanylate cyclase 2C -0.00780794
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.00780647
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.0078026
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.00775171
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00774123
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00772788
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00771678
ENDOD1 endonuclease domain containing 1 -0.00770789
ITK IL2-inducible T-cell kinase -0.0076985
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00769521
STXBP6 syntaxin binding protein 6 (amisyn) -0.00761948
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00760513
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00759768
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00759618
ACTA1 actin, alpha 1, skeletal muscle -0.00757767
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00757604
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00756925
MFAP3L microfibrillar-associated protein 3-like -0.00755035
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00754982
IGF1R insulin-like growth factor 1 receptor -0.00751015
PLAUR plasminogen activator, urokinase receptor -0.0074751
CAPRIN2 caprin family member 2 -0.00746645
CLDN10 claudin 10 -0.00746214
RGS4 regulator of G-protein signaling 4 -0.00744864
SH3YL1 SH3 and SYLF domain containing 1 -0.00744359
HCP5 HLA complex P5 (non-protein coding) -0.00742547
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.0074087
CRISP3 cysteine-rich secretory protein 3 -0.0074072
ANOS1 anosmin 1 -0.00740222
NTS neurotensin -0.00738847
CRABP1 cellular retinoic acid binding protein 1 -0.00736786
S100A11 S100 calcium binding protein A11 -0.00735043
AIM2 absent in melanoma 2 -0.00733006
MFSD10 major facilitator superfamily domain containing 10 -0.00732337
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -0.00732069
GAP43 growth associated protein 43 -0.00730749
NEBL nebulette -0.0072904
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00728262
TUBA4A tubulin, alpha 4a -0.00727765
MXI1 MAX interactor 1, dimerization protein -0.00727184
CLIC5 chloride intracellular channel 5 -0.00725408
BMP2 bone morphogenetic protein 2 -0.00725083
HSPA12A heat shock 70kDa protein 12A -0.007211
LRRC8D leucine rich repeat containing 8 family, member D -0.0071543
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00715126
RAB29 RAB29, member RAS oncogene family -0.00714353
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00712086
KRT17 keratin 17, type I -0.00709171
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00709035
GPM6B glycoprotein M6B -0.00707975
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -0.00707751
ANXA3 annexin A3 -0.00705224
XAF1 XIAP associated factor 1 -0.0070487
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00703609
MT1G metallothionein 1G -0.0070177
ANK2 ankyrin 2, neuronal -0.00700413
TNIK TRAF2 and NCK interacting kinase -0.0069895
MYOF myoferlin -0.00698579
KRT23 keratin 23, type I -0.00698429
IRS2 insulin receptor substrate 2 -0.00697321
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00696929
IRF7 interferon regulatory factor 7 -0.00696506
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00695272
FXYD5 FXYD domain containing ion transport regulator 5 -0.00693721
NEFM neurofilament, medium polypeptide -0.0069333
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00693063
LRP4 low density lipoprotein receptor-related protein 4 -0.00692474
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00691641
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00691545
BDNF brain-derived neurotrophic factor -0.00691502
NES nestin -0.00691496
EGR1 early growth response 1 -0.00690515
S100A10 S100 calcium binding protein A10 -0.00690143
EDNRB endothelin receptor type B -0.00688404
NPR3 natriuretic peptide receptor 3 -0.00687422
ZCCHC2 zinc finger, CCHC domain containing 2 -0.00687266
BAX BCL2-associated X protein -0.00686676
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00686668
IER2 immediate early response 2 -0.00684276
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00683719
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -0.00683435
NIPSNAP1 nipsnap homolog 1 (C. elegans) -0.00683052
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.0068283
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00682732
SMAD3 SMAD family member 3 -0.00679178
PEG10 paternally expressed 10 -0.00678959
LIF leukemia inhibitory factor -0.00678909
OSBPL9 oxysterol binding protein-like 9 -0.00678275
SELL selectin L -0.00677148
MYO1C myosin IC -0.00675883
HLA-F major histocompatibility complex, class I, F -0.00674204
AFTPH aftiphilin -0.00673358
MPO myeloperoxidase -0.00672785
SMPX small muscle protein, X-linked -0.00672632
SOX9 SRY (sex determining region Y)-box 9 -0.00670591
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00670296
AQP3 aquaporin 3 (Gill blood group) -0.0067015
HIST1H2AC histone cluster 1, H2ac -0.00668226
COL9A3 collagen, type IX, alpha 3 -0.00667676
NARS1 asparaginyl-tRNA synthetase 1 -0.00666618
SLN sarcolipin -0.00663729
MT1H metallothionein 1H -0.00663434