STAT1 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description signal transducer and activator of transcription 1, 91kDa|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6772)
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Genes

179 target genes of the STAT1 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ADAL adenosine deaminase-like
AGRP agouti related neuropeptide
AKAP1 A kinase (PRKA) anchor protein 1
AQR aquarius intron-binding spliceosomal factor
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASXL1 additional sex combs like transcriptional regulator 1
ATN1 atrophin 1
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATXN7L2 ataxin 7-like 2
BCAP31 B-cell receptor-associated protein 31
BCR breakpoint cluster region
BCRP3 breakpoint cluster region pseudogene 3
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRCA1 breast cancer 1, early onset
BSX brain-specific homeobox
BTBD3 BTB (POZ) domain containing 3
C11ORF73 chromosome 11 open reading frame 73
C11ORF74 chromosome 11 open reading frame 74
C19ORF66 chromosome 19 open reading frame 66
C1ORF94 chromosome 1 open reading frame 94
C2 complement component 2
C21ORF62 chromosome 21 open reading frame 62
C9ORF135 chromosome 9 open reading frame 135
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CCDC178 coiled-coil domain containing 178
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CCR3 chemokine (C-C motif) receptor 3
CD40LG CD40 ligand
CD86 CD86 molecule
COL14A1 collagen, type XIV, alpha 1
COQ9 coenzyme Q9
CREM cAMP responsive element modulator
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTNND1 catenin (cadherin-associated protein), delta 1
DACT3-AS1 DACT3 antisense RNA 1
DGKA diacylglycerol kinase, alpha 80kDa
DLL4 delta-like 4 (Drosophila)
DMTN dematin actin binding protein
DRC7 dynein regulatory complex subunit 7
DTX2 deltex 2, E3 ubiquitin ligase
DYSF dysferlin
EIF3C eukaryotic translation initiation factor 3, subunit C
ENY2 enhancer of yellow 2 homolog (Drosophila)
EVL Enah/Vasp-like
FAM65C family with sequence similarity 65, member C
FANCM Fanconi anemia, complementation group M
FBL fibrillarin
FBN2 fibrillin 2
FCHSD2 FCH and double SH3 domains 2
FGGY FGGY carbohydrate kinase domain containing
FOXA3 forkhead box A3
FOXN3-AS1 FOXN3 antisense RNA 1
FOXO3 forkhead box O3
FUS FUS RNA binding protein
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GEN1 GEN1 Holliday junction 5' flap endonuclease
GK glycerol kinase
GLB1L galactosidase, beta 1-like
GNG2 guanine nucleotide binding protein (G protein), gamma 2
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
IER3 immediate early response 3
IFT43 intraflagellar transport 43
IL10 interleukin 10
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
ITPKC inositol-trisphosphate 3-kinase C
JMJD1C jumonji domain containing 1C
KIAA1217 KIAA1217
KIAA1598
KIRREL kin of IRRE like (Drosophila)
KMT2B lysine (K)-specific methyltransferase 2B
LAPTM4B lysosomal protein transmembrane 4 beta
LEP leptin
LIMCH1 LIM and calponin homology domains 1
LIN28A lin-28 homolog A (C. elegans)
LOC100130264 uncharacterized LOC100130264
LPL lipoprotein lipase
LTA lymphotoxin alpha
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K3 mitogen-activated protein kinase kinase 3
MAP3K14-AS1 MAP3K14 antisense RNA 1
MAP7D1 MAP7 domain containing 1
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MARCKS myristoylated alanine-rich protein kinase C substrate
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGA MGA, MAX dimerization protein
MIR1205 microRNA 1205
MIR1206 microRNA 1206
MIR218-1 microRNA 218-1
MIR2392 microRNA 2392
MIR3662 microRNA 3662
MIR4257 microRNA 4257
MIR4679-1 microRNA 4679-1
MIR5047 microRNA 5047
MIR548AX microRNA 548ax
MIR548Q microRNA 548q
MRAP2 melanocortin 2 receptor accessory protein 2
MRPL54 mitochondrial ribosomal protein L54
MRPS18A mitochondrial ribosomal protein S18A
MUC1 mucin 1, cell surface associated
MYO9A myosin IXA
NKG7 natural killer cell granule protein 7
NOS3 nitric oxide synthase 3 (endothelial cell)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OCM2 oncomodulin 2
ORAI1 ORAI calcium release-activated calcium modulator 1
PAAF1 proteasomal ATPase-associated factor 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARP14 poly (ADP-ribose) polymerase family, member 14
PHACTR3 phosphatase and actin regulator 3
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PKDCC protein kinase domain containing, cytoplasmic
PODN podocan
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPARD peroxisome proliferator-activated receptor delta
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRDM5 PR domain containing 5
PROX2 prospero homeobox 2
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
RAB3D RAB3D, member RAS oncogene family
RALYL RALY RNA binding protein-like
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RBM26 RNA binding motif protein 26
RBM5 RNA binding motif protein 5
RFX4 regulatory factor X, 4 (influences HLA class II expression)
RIMKLB ribosomal modification protein rimK-like family member B
RNU6-16P RNA, U6 small nuclear 16, pseudogene
RPP40 ribonuclease P/MRP 40kDa subunit
RUNX1 runt-related transcription factor 1
SDCBP2-AS1 SDCBP2 antisense RNA 1
SDF2 stromal cell-derived factor 2
SDHAF2 succinate dehydrogenase complex assembly factor 2
SERTAD3 SERTA domain containing 3
SH3RF2 SH3 domain containing ring finger 2
SLC38A3 solute carrier family 38, member 3
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLIT3 slit homolog 3 (Drosophila)
SMLR1 small leucine-rich protein 1
SNAPIN SNAP-associated protein
SNORD112 small nucleolar RNA, C/D box 112
SOCS1 suppressor of cytokine signaling 1
SRA1 steroid receptor RNA activator 1
SSTR2 somatostatin receptor 2
STARD8 StAR-related lipid transfer (START) domain containing 8
TCEA2 transcription elongation factor A (SII), 2
TCERG1 transcription elongation regulator 1
THRAP3 thyroid hormone receptor associated protein 3
TLR7 toll-like receptor 7
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMEM208 transmembrane protein 208
TMEM43 transmembrane protein 43
TMOD3 tropomodulin 3 (ubiquitous)
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOB1-AS1 TOB1 antisense RNA 1
TPI1P2 triosephosphate isomerase 1 pseudogene 2
TRAIP TRAF interacting protein
TRIM69 tripartite motif containing 69
TSPAN33 tetraspanin 33
TSPAN8 tetraspanin 8
UBE2B ubiquitin-conjugating enzyme E2B
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VARS valyl-tRNA synthetase
VRK1 vaccinia related kinase 1
ZNF207 zinc finger protein 207
ZNF226 zinc finger protein 226
ZNF227 zinc finger protein 227
ZNF233 zinc finger protein 233
ZNF234 zinc finger protein 234
ZNF283 zinc finger protein 283
ZNF582-AS1 ZNF582 antisense RNA 1 (head to head)
ZNF79 zinc finger protein 79