| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | signal transducer and activator of transcription 3 (acute-phase response factor)|The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6774) |
| External Link | https://ncbi.nlm.nih.gov/gene/6774 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the STAT3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 0.0100189 |
| SYT1 | synaptotagmin I | 0.00881469 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00868637 |
| NTS | neurotensin | 0.00864461 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00854546 |
| ADIRF | adipogenesis regulatory factor | 0.00839953 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00815529 |
| PON2 | paraoxonase 2 | 0.00772762 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00772529 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00771658 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00745572 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00728544 |
| LXN | latexin | 0.00727492 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00727336 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00725004 |
| OLFM4 | olfactomedin 4 | 0.00714368 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00701978 |
| LEFTY1 | left-right determination factor 1 | 0.00697824 |
| JAG1 | jagged 1 | 0.00669704 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00664073 |
| ADD3 | adducin 3 (gamma) | 0.00653505 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00650884 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00648179 |
| CALB1 | calbindin 1, 28kDa | 0.00625977 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00622567 |
| CLU | clusterin | 0.00603436 |
| TOB1 | transducer of ERBB2, 1 | 0.00596766 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.0059589 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00595672 |
| IL1RL1 | interleukin 1 receptor-like 1 | 0.00591342 |
| GPM6B | glycoprotein M6B | 0.00588686 |
| KRT20 | keratin 20, type I | 0.00587854 |
| GOLM1 | golgi membrane protein 1 | 0.00587479 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00585034 |
| IDE | insulin-degrading enzyme | 0.00582381 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00580825 |
| RHOB | ras homolog family member B | 0.00574465 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00573957 |
| MAP7 | microtubule-associated protein 7 | 0.00573288 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00572094 |
| MT1X | metallothionein 1X | 0.00571833 |
| CYCS | cytochrome c, somatic | 0.00569502 |
| MID1 | midline 1 | 0.00567533 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | 0.00564956 |
| GALC | galactosylceramidase | 0.00564364 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00559383 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0055433 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00550877 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00544986 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00544857 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.00544222 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00542167 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00531808 |
| AGR2 | anterior gradient 2 | 0.00529468 |
| GDF15 | growth differentiation factor 15 | 0.00527869 |
| HEPH | hephaestin | 0.00526698 |
| GGCT | gamma-glutamylcyclotransferase | 0.00516406 |
| HAT1 | histone acetyltransferase 1 | 0.00511551 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00511375 |
| VWF | von Willebrand factor | 0.00510402 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00510203 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.0050845 |
| MMD | monocyte to macrophage differentiation-associated | 0.00507108 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00506216 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.00500373 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00499081 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.00498429 |
| EDN1 | endothelin 1 | 0.00493225 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.0049058 |
| RGS1 | regulator of G-protein signaling 1 | 0.00490493 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0048927 |
| CBR3 | carbonyl reductase 3 | 0.00487133 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00484195 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00484101 |
| WWC1 | WW and C2 domain containing 1 | 0.00483129 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00482629 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00482272 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00481814 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00480455 |
| TYRP1 | tyrosinase-related protein 1 | 0.00479816 |
| XIC | X chromosome inactivation center | 0.00479161 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | 0.00475621 |
| CTBP2 | C-terminal binding protein 2 | 0.00475127 |
| CFD | complement factor D (adipsin) | 0.00474629 |
| GLUD1 | glutamate dehydrogenase 1 | 0.0046966 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00469464 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00469307 |
| ACE2 | angiotensin I converting enzyme 2 | 0.00468095 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00467867 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00465346 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00464966 |
| EVI2A | ecotropic viral integration site 2A | 0.00464501 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00463776 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00457336 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00457107 |
| RUNX3 | runt-related transcription factor 3 | 0.00456137 |
| RCAN1 | regulator of calcineurin 1 | 0.00455646 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00455623 |
| POMZP3 | POM121 and ZP3 fusion | 0.00454722 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 0.00452407 |
| CCNB2 | cyclin B2 | 0.00451752 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00450597 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00449547 |
| DACH1 | dachshund family transcription factor 1 | 0.00449129 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00443165 |
| REG3A | regenerating islet-derived 3 alpha | 0.00443127 |
| FJX1 | four jointed box 1 (Drosophila) | 0.00440787 |
| FST | follistatin | 0.00440315 |
| SMAD3 | SMAD family member 3 | 0.00439393 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00437491 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00434594 |
| TM4SF20 | transmembrane 4 L six family member 20 | 0.00434465 |
| PNMA8A | PNMA family member 8A | 0.00433648 |
| NGRN | neugrin, neurite outgrowth associated | 0.00432275 |
| TAC1 | tachykinin, precursor 1 | 0.00431579 |
| RGS20 | regulator of G-protein signaling 20 | 0.0043137 |
| SELE | selectin E | 0.00430475 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00429092 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 0.00428668 |
| HOXB7 | homeobox B7 | 0.004283 |
| FAM107A | family with sequence similarity 107, member A | 0.0042769 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.00427386 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00426079 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00425565 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.00425288 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00424755 |
| SPRR3 | small proline-rich protein 3 | 0.00424374 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00423357 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00422877 |
| SEC61G | Sec61 gamma subunit | 0.00422344 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00421833 |
| CAST | calpastatin | 0.0042179 |
| MGAM | maltase-glucoamylase | 0.00421456 |
| PRSS3 | protease, serine, 3 | 0.00414566 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00414133 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0041409 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00413758 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00412606 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.00412467 |
| PDCD10 | programmed cell death 10 | 0.00409409 |
| FANCI | Fanconi anemia, complementation group I | 0.00409315 |
| EFCAB11 | EF-hand calcium binding domain 11 | 0.00409169 |
| TARP | TCR gamma alternate reading frame protein | 0.00407794 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.00404708 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00404591 |
| PAX5 | paired box 5 | 0.00403917 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.00403187 |
| CAPN1 | calpain 1, (mu/I) large subunit | 0.00402697 |
| ODC1 | ornithine decarboxylase 1 | 0.00402296 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00401934 |
| ABLIM1 | actin binding LIM protein 1 | 0.00401282 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | 0.00401269 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0040117 |
| NANS | N-acetylneuraminic acid synthase | 0.00400967 |
| SYBU | syntabulin (syntaxin-interacting) | 0.0040027 |
| TRIM29 | tripartite motif containing 29 | 0.0039975 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00397765 |
| RNF187 | ring finger protein 187 | 0.0039534 |
| AOC1 | amine oxidase, copper containing 1 | 0.00395276 |
| HOXC6 | homeobox C6 | 0.00394689 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00394596 |
| COL5A2 | collagen, type V, alpha 2 | 0.00394245 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00394165 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.0039347 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00393029 |
| CRAT | carnitine O-acetyltransferase | 0.00391946 |
| KLK10 | kallikrein-related peptidase 10 | 0.0039136 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00391111 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00390801 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0038913 |
| MT1H | metallothionein 1H | 0.00388558 |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | 0.00388094 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00387047 |
| CALML4 | calmodulin-like 4 | 0.00386577 |
| GMPS | guanine monphosphate synthase | 0.00386422 |
| MT1F | metallothionein 1F | 0.00386247 |
| CHMP4A | charged multivesicular body protein 4A | 0.00385737 |
| SFN | stratifin | 0.00385298 |
| BLNK | B-cell linker | 0.00385185 |
| HOXB6 | homeobox B6 | 0.00384834 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00384762 |
| MINK1 | misshapen-like kinase 1 | 0.00384692 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00383933 |
| NDE1 | nudE neurodevelopment protein 1 | 0.00383527 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00381699 |
| RNF144A | ring finger protein 144A | 0.00381526 |
| BTBD1 | BTB (POZ) domain containing 1 | 0.00380456 |
| METRN | meteorin, glial cell differentiation regulator | 0.00380022 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00379978 |
| MT1E | metallothionein 1E | 0.00378015 |
| NEK2 | NIMA-related kinase 2 | 0.00377771 |
| MTIF2 | mitochondrial translational initiation factor 2 | 0.00377579 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00377068 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00376583 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00375546 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00375386 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00375372 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00374639 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00374492 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00373962 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00373506 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.00371844 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00371726 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00370663 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00369817 |
| MT1G | metallothionein 1G | 0.00369649 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.00368221 |
| MMP10 | matrix metallopeptidase 10 | 0.00367995 |
| EAF2 | ELL associated factor 2 | 0.00367884 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.00367695 |
| DOCK4 | dedicator of cytokinesis 4 | 0.00367592 |
| SST | somatostatin | 0.00366605 |
| GPX2 | glutathione peroxidase 2 | 0.00365047 |
| IFT27 | intraflagellar transport 27 | 0.00365022 |
| ADI1 | acireductone dioxygenase 1 | 0.00364647 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00364106 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.00363843 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.00363672 |
| TEX30 | testis expressed 30 | 0.00363246 |
| CLDN5 | claudin 5 | 0.00362646 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | 0.0036215 |
| PYCARD | PYD and CARD domain containing | 0.00362104 |
| STON1 | stonin 1 | 0.00361436 |
| BMP7 | bone morphogenetic protein 7 | 0.00360678 |
| CD9 | CD9 molecule | 0.00360514 |
| MAGEA3 | melanoma antigen family A3 | 0.00360412 |
| IQCK | IQ motif containing K | 0.0035995 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00359666 |
| REG1A | regenerating islet-derived 1 alpha | 0.00359361 |
| KIF5C | kinesin family member 5C | 0.00359347 |
| ADNP2 | ADNP homeobox 2 | 0.00359142 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.00358865 |
| EML1 | echinoderm microtubule associated protein like 1 | 0.00358498 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00358416 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | 0.00357307 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00356858 |
| PLA1A | phospholipase A1 member A | 0.00356126 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | 0.00356102 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00353867 |
| FDXR | ferredoxin reductase | 0.00353816 |
| S1PR1 | sphingosine-1-phosphate receptor 1 | 0.00353619 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00352967 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00352835 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00352331 |
| WISP1 | WNT1 inducible signaling pathway protein 1 | 0.00351922 |
| ANXA1 | annexin A1 | 0.00351757 |
| LCN2 | lipocalin 2 | 0.00351488 |
| JMJD6 | jumonji domain containing 6 | 0.00349613 |
| MID1IP1 | MID1 interacting protein 1 | 0.00349459 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00977859 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00975005 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0096732 |
| SDC2 | syndecan 2 | -0.00890766 |
| GPX3 | glutathione peroxidase 3 | -0.00882346 |
| POSTN | periostin, osteoblast specific factor | -0.00866651 |
| TCTA | T-cell leukemia translocation altered | -0.00838569 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00819996 |
| ITM2A | integral membrane protein 2A | -0.00804617 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00783364 |
| GPER1 | G protein-coupled estrogen receptor 1 | -0.00775118 |
| FGG | fibrinogen gamma chain | -0.00749969 |
| CTSH | cathepsin H | -0.0073767 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00732519 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00730046 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00695875 |
| FN1 | fibronectin 1 | -0.00693962 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00676937 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00675952 |
| G0S2 | G0/G1 switch 2 | -0.00675071 |
| PEG3 | paternally expressed 3 | -0.00672786 |
| CD164 | CD164 molecule, sialomucin | -0.00666255 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00661959 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00660248 |
| SLN | sarcolipin | -0.00660168 |
| COL1A2 | collagen, type I, alpha 2 | -0.00636938 |
| DNM1L | dynamin 1-like | -0.00623487 |
| HNMT | histamine N-methyltransferase | -0.00614438 |
| PLD3 | phospholipase D family, member 3 | -0.00611985 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00611558 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00608451 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00606602 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00596241 |
| LAMB3 | laminin, beta 3 | -0.00593622 |
| CKM | creatine kinase, muscle | -0.0059278 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.0058733 |
| OBSL1 | obscurin-like 1 | -0.00585744 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00580333 |
| TTN | titin | -0.0057941 |
| ALB | albumin | -0.00578343 |
| RTN2 | reticulon 2 | -0.00575047 |
| SIRT3 | sirtuin 3 | -0.00572838 |
| TNNC2 | troponin C type 2 (fast) | -0.00572749 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00566512 |
| ORM1 | orosomucoid 1 | -0.00563111 |
| COLEC12 | collectin sub-family member 12 | -0.00561595 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00561269 |
| A2M | alpha-2-macroglobulin | -0.00559616 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.0055878 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00556243 |
| TLR4 | toll-like receptor 4 | -0.00554663 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00554162 |
| COL3A1 | collagen, type III, alpha 1 | -0.00553489 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00553428 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00550917 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00550439 |
| C4BPA | complement component 4 binding protein, alpha | -0.00547815 |
| CDA | cytidine deaminase | -0.00547499 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00547207 |
| GANAB | glucosidase, alpha; neutral AB | -0.00543041 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00542625 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.0053936 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00539197 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.00539107 |
| GPC3 | glypican 3 | -0.00536337 |
| CAPNS1 | calpain, small subunit 1 | -0.00536158 |
| HAMP | hepcidin antimicrobial peptide | -0.00536154 |
| CD14 | CD14 molecule | -0.00533717 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00531266 |
| YME1L1 | YME1-like 1 ATPase | -0.00529649 |
| C4BPB | complement component 4 binding protein, beta | -0.00528379 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.0051854 |
| MYOT | myotilin | -0.00515733 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00514416 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00510183 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00509667 |
| GSN | gelsolin | -0.00507513 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00506943 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00506451 |
| CES1 | carboxylesterase 1 | -0.00505968 |
| BCHE | butyrylcholinesterase | -0.00504714 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00501809 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.00501419 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00501102 |
| SPART | spartin | -0.00501059 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00498643 |
| CFI | complement factor I | -0.00496451 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00496276 |
| SFTPB | surfactant protein B | -0.00494178 |
| MGLL | monoglyceride lipase | -0.00492651 |
| VWA1 | von Willebrand factor A domain containing 1 | -0.0049265 |
| CD151 | CD151 molecule (Raph blood group) | -0.00492149 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00489612 |
| TMEM259 | transmembrane protein 259 | -0.00489445 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00488184 |
| HLA-C | major histocompatibility complex, class I, C | -0.00487981 |
| EXPH5 | exophilin 5 | -0.00485244 |
| TXNIP | thioredoxin interacting protein | -0.00484538 |
| REEP1 | receptor accessory protein 1 | -0.00483903 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00481757 |
| GAS2 | growth arrest-specific 2 | -0.00479612 |
| MIA | melanoma inhibitory activity | -0.00478015 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00476312 |
| C5 | complement component 5 | -0.00474774 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00474451 |
| RAPSN | receptor-associated protein of the synapse | -0.00473526 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00473297 |
| AHSG | alpha-2-HS-glycoprotein | -0.0047284 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00471898 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00470713 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00470393 |
| DAPK1 | death-associated protein kinase 1 | -0.0046909 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00468548 |
| KLHDC3 | kelch domain containing 3 | -0.00467048 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00466771 |
| CCND1 | cyclin D1 | -0.00465653 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | -0.00463411 |
| MCOLN1 | mucolipin 1 | -0.00461926 |
| EGR2 | early growth response 2 | -0.00461654 |
| HLA-B | major histocompatibility complex, class I, B | -0.00460007 |
| CA9 | carbonic anhydrase IX | -0.00458273 |
| GSAP | gamma-secretase activating protein | -0.00455351 |
| PER3 | period circadian clock 3 | -0.00454032 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00452179 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00450907 |
| TSPAN8 | tetraspanin 8 | -0.0044905 |
| TMEM45A | transmembrane protein 45A | -0.00448659 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | -0.00446786 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.00446259 |
| APOA2 | apolipoprotein A-II | -0.00445264 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0044506 |
| RCAN2 | regulator of calcineurin 2 | -0.00443705 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.00442078 |
| BSG | basigin (Ok blood group) | -0.00441046 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00439151 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00439083 |
| PFKL | phosphofructokinase, liver | -0.00438633 |
| NEK7 | NIMA-related kinase 7 | -0.00434415 |
| MB | myoglobin | -0.00434366 |
| KLHL41 | kelch-like family member 41 | -0.00434245 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -0.00434195 |
| TNC | tenascin C | -0.00433441 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00432777 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | -0.00431797 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.00430523 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00429938 |
| RGN | regucalcin | -0.00429604 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.00426689 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.00426183 |
| TMEM230 | transmembrane protein 230 | -0.00426145 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00426013 |
| ANXA6 | annexin A6 | -0.00425698 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -0.00425394 |
| TBCB | tubulin folding cofactor B | -0.00425034 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.0042452 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00424354 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00422523 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.00421199 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00420844 |
| RRBP1 | ribosome binding protein 1 | -0.00417544 |
| TENM3 | teneurin transmembrane protein 3 | -0.00417231 |
| ANGPT1 | angiopoietin 1 | -0.00416998 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00415349 |
| PLBD1 | phospholipase B domain containing 1 | -0.00414706 |
| FGA | fibrinogen alpha chain | -0.00414704 |
| SFTPA2 | surfactant protein A2 | -0.00414122 |
| DMD | dystrophin | -0.00413408 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00412358 |
| SFTPC | surfactant protein C | -0.0041211 |
| FLOT1 | flotillin 1 | -0.00410119 |
| DENND1B | DENN/MADD domain containing 1B | -0.00410027 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0040998 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.00409553 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -0.00409548 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00408998 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00408424 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00407184 |
| DHFR | dihydrofolate reductase | -0.00405539 |
| PON3 | paraoxonase 3 | -0.00404913 |
| EPS8L2 | EPS8-like 2 | -0.0040383 |
| AMPD3 | adenosine monophosphate deaminase 3 | -0.00403721 |
| ATP13A3 | ATPase type 13A3 | -0.00403241 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00402175 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.00402069 |
| ADAMTSL3 | ADAMTS-like 3 | -0.0040141 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | -0.00401071 |
| NRN1 | neuritin 1 | -0.004007 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0039989 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00399757 |
| FHL1 | four and a half LIM domains 1 | -0.00399501 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -0.00399089 |
| NNAT | neuronatin | -0.00398369 |
| IL17B | interleukin 17B | -0.00397187 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00396721 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00396317 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00392484 |
| CSTB | cystatin B (stefin B) | -0.00392197 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00390993 |
| CPM | carboxypeptidase M | -0.00390974 |
| MPZL2 | myelin protein zero-like 2 | -0.00389307 |
| SMPX | small muscle protein, X-linked | -0.00388783 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00388114 |
| ITGA6 | integrin, alpha 6 | -0.00387362 |
| AQP5 | aquaporin 5 | -0.00386667 |
| ASGR2 | asialoglycoprotein receptor 2 | -0.00385819 |
| CALR | calreticulin | -0.00385049 |
| PRNP | prion protein | -0.00384784 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.0038335 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00383058 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00382818 |
| LUM | lumican | -0.00381974 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | -0.00381366 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00380301 |
| PPL | periplakin | -0.00378643 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0037854 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.0037839 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | -0.00378348 |
| HK2 | hexokinase 2 | -0.00378197 |
| LAMA4 | laminin, alpha 4 | -0.00377996 |
| TXLNA | taxilin alpha | -0.00377645 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00377519 |
| PGRMC2 | progesterone receptor membrane component 2 | -0.00377249 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00377182 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00376895 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | -0.00376462 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.00376238 |
| STK26 | serine/threonine protein kinase 26 | -0.00372773 |
| GSE1 | Gse1 coiled-coil protein | -0.00371888 |
| PCYOX1 | prenylcysteine oxidase 1 | -0.00371714 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00371561 |
| DENND2B | DENN domain containing 2B | -0.00370482 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00370431 |
| FGL2 | fibrinogen-like 2 | -0.00370299 |
| TNNC1 | troponin C type 1 (slow) | -0.00370266 |
| IL1RN | interleukin 1 receptor antagonist | -0.00369944 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00369184 |
| EHBP1 | EH domain binding protein 1 | -0.00369146 |
| NPTN | neuroplastin | -0.003687 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00367933 |
| NES | nestin | -0.00366499 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.00364994 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | -0.00363875 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00363299 |
| HLA-F | major histocompatibility complex, class I, F | -0.00363131 |
| PCNA | proliferating cell nuclear antigen | -0.00362856 |
| HCRTR1 | hypocretin (orexin) receptor 1 | -0.00361703 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00360191 |
| HOPX | HOP homeobox | -0.00359835 |
| S100A4 | S100 calcium binding protein A4 | -0.00359723 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00358938 |
