STAT3_01_49 Gene Set

Dataset KnockTF Gene Expression Profiles with Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description STAT3 siRNA knock from prostate cell line (KnockTF, DataSet_01_49)
External Link http://www.licpathway.net/KnockTF/search/search_sample_result.php?sample_id=DataSet_01_49
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Genes

200 genesdifferentially expressed following the STAT3_01_49 trascription factor perturbation from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
TST thiosulfate sulfurtransferase (rhodanese) 5.14265
NME3 NME/NM23 nucleoside diphosphate kinase 3 3.94901
TXNIP thioredoxin interacting protein 3.91415
IRF9 interferon regulatory factor 9 3.80845
SERTAD3 SERTA domain containing 3 3.76538
NINJ1 ninjurin 1 3.75494
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 3.69432
SDF2L1 stromal cell-derived factor 2-like 1 3.68652
HIST1H1C histone cluster 1, H1c 3.67324
HIST3H2A histone cluster 3, H2a 3.65872
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 3.59064
SCAND1 SCAN domain containing 1 3.57557
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 3.5088
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 3.48702
PLK1 polo-like kinase 1 3.48626
PRR14 proline rich 14 3.46354
PRRX2 paired related homeobox 2 3.46293
IP6K2 inositol hexakisphosphate kinase 2 3.46037
POMT1 protein-O-mannosyltransferase 1 3.42514
PTGES prostaglandin E synthase 3.41492
ACOT8 acyl-CoA thioesterase 8 3.37799
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 3.36417
LAGE3 L antigen family, member 3 3.35016
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 3.28906
GPRC5C G protein-coupled receptor, class C, group 5, member C 3.2459
IL17RA interleukin 17 receptor A 3.22635
NT5C 5', 3'-nucleotidase, cytosolic 3.22625
EXOSC5 exosome component 5 3.22415
DDIT3 DNA-damage-inducible transcript 3 3.20014
PTGES2 prostaglandin E synthase 2 3.19603
TIMP2 TIMP metallopeptidase inhibitor 2 3.19097
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) 3.18492
ABHD11 abhydrolase domain containing 11 3.17738
AIP aryl hydrocarbon receptor interacting protein 3.17358
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 3.13402
KIFC3 kinesin family member C3 3.11042
HS1BP3 HCLS1 binding protein 3 3.1007
SCAMP2 secretory carrier membrane protein 2 3.10009
TRIB3 tribbles pseudokinase 3 3.09309
MPST mercaptopyruvate sulfurtransferase 3.06514
TUSC2 tumor suppressor candidate 2 3.03262
TPST1 tyrosylprotein sulfotransferase 1 2.98937
RHOD ras homolog family member D 2.98044
MUL1 mitochondrial E3 ubiquitin protein ligase 1 2.96472
TESC tescalcin 2.95304
DDAH2 dimethylarginine dimethylaminohydrolase 2 2.9517
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 2.95031
ZMYM3 zinc finger, MYM-type 3 2.94985
EGFL7 EGF-like-domain, multiple 7 2.93785
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.93759
NMB neuromedin B 2.93515
TWF2 twinfilin actin binding protein 2 2.93193
TMEM187 transmembrane protein 187 2.93168
LCMT1 leucine carboxyl methyltransferase 1 2.93158
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.92544
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 2.92191
SIRT2 sirtuin 2 2.92129
NLRX1 NLR family member X1 2.9028
SLC41A3 solute carrier family 41, member 3 2.89933
PANK4 pantothenate kinase 4 2.89056
OCEL1 occludin/ELL domain containing 1 2.88331
ANAPC2 anaphase promoting complex subunit 2 2.87425
ETFB electron-transfer-flavoprotein, beta polypeptide 2.85981
BAD BCL2-associated agonist of cell death 2.85445
MIIP migration and invasion inhibitory protein 2.85128
PNPLA6 patatin-like phospholipase domain containing 6 2.83836
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 2.83414
ISG15 ISG15 ubiquitin-like modifier 2.83212
EPS8L2 EPS8-like 2 2.82822
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 2.8231
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 2.81989
SIPA1 signal-induced proliferation-associated 1 2.81359
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 2.81319
ISOC2 isochorismatase domain containing 2 2.80303
CAPG capping protein (actin filament), gelsolin-like 2.77589
MLPH melanophilin 2.77308
COG4 component of oligomeric golgi complex 4 2.75359
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.74312
CDA cytidine deaminase 2.73916
MPPE1 metallophosphoesterase 1 2.73763
TCEA2 transcription elongation factor A (SII), 2 2.73326
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.72845
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.7091
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 2.70514
EPHB4 EPH receptor B4 2.70488
PMVK phosphomevalonate kinase 2.70229
CST3 cystatin C 2.69546
NAGK N-acetylglucosamine kinase 2.69511
CLK3 CDC-like kinase 3 2.68736
ORAI3 ORAI calcium release-activated calcium modulator 3 2.67668
TMEM161A transmembrane protein 161A 2.67298
TMEM106C transmembrane protein 106C 2.66728
ACADVL acyl-CoA dehydrogenase, very long chain 2.65996
ANKZF1 ankyrin repeat and zinc finger domain containing 1 2.65733
LMAN2L lectin, mannose-binding 2-like 2.64752
TECR trans-2,3-enoyl-CoA reductase 2.64312
RABEPK Rab9 effector protein with kelch motifs 2.63377
DVL2 dishevelled segment polarity protein 2 2.63357
GMPPA GDP-mannose pyrophosphorylase A 2.62635
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 2.62567

decreased expression

Symbol Name Standardized Value
ARID4A AT rich interactive domain 4A (RBP1-like) -0.65547
COX7B cytochrome c oxidase subunit VIIb -0.65174
SLC39A9 solute carrier family 39, member 9 -0.6517
CLGN calmegin -0.65098
HELZ helicase with zinc finger -0.64979
DROSHA drosha, ribonuclease type III -0.64952
SNX24 sorting nexin 24 -0.64937
GPHN gephyrin -0.64821
RPL27A ribosomal protein L27a -0.64747
ERH enhancer of rudimentary homolog (Drosophila) -0.64635
TBL2 transducin (beta)-like 2 -0.64622
SOX9 SRY (sex determining region Y)-box 9 -0.64428
ZNF432 zinc finger protein 432 -0.64426
CC2D1A coiled-coil and C2 domain containing 1A -0.64323
EML4 echinoderm microtubule associated protein like 4 -0.64317
HMGN2 high mobility group nucleosomal binding domain 2 -0.64203
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.64139
SH2D4A SH2 domain containing 4A -0.64115
IQGAP1 IQ motif containing GTPase activating protein 1 -0.64113
MKI67 marker of proliferation Ki-67 -0.6409
POMZP3 POM121 and ZP3 fusion -0.64016
NCOA6 nuclear receptor coactivator 6 -0.63902
TPST2 tyrosylprotein sulfotransferase 2 -0.63831
SMAD7 SMAD family member 7 -0.63806
STK4 serine/threonine kinase 4 -0.63659
PTK2 protein tyrosine kinase 2 -0.63599
ERAP1 endoplasmic reticulum aminopeptidase 1 -0.63598
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.63586
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.63429
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.63374
ANAPC13 anaphase promoting complex subunit 13 -0.63289
NSL1 NSL1, MIS12 kinetochore complex component -0.63196
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -0.63195
ELOVL5 ELOVL fatty acid elongase 5 -0.63182
PLAGL1 pleiomorphic adenoma gene-like 1 -0.63139
KCNK5 potassium channel, two pore domain subfamily K, member 5 -0.62919
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.62836
FBXW2 F-box and WD repeat domain containing 2 -0.62812
APH1A APH1A gamma secretase subunit -0.62792
MACF1 microtubule-actin crosslinking factor 1 -0.627
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -0.62638
NOL11 nucleolar protein 11 -0.62505
ZNF587 zinc finger protein 587 -0.62483
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -0.62479
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -0.62364
MED15 mediator complex subunit 15 -0.62141
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -0.61799
SPATA2L spermatogenesis associated 2-like -0.61715
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -0.61708
HHLA3 HERV-H LTR-associating 3 -0.61703
CLK4 CDC-like kinase 4 -0.61387
RPS7 ribosomal protein S7 -0.61384
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.6132
MAT2B methionine adenosyltransferase II, beta -0.61308
NUP205 nucleoporin 205kDa -0.61278
FBXL18 F-box and leucine-rich repeat protein 18 -0.61207
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -0.61192
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.61176
ZNF85 zinc finger protein 85 -0.61104
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.6106
FOXJ3 forkhead box J3 -0.60926
ZBED4 zinc finger, BED-type containing 4 -0.60804
ZNF814 zinc finger protein 814 -0.60746
NCBP2 nuclear cap binding protein subunit 2, 20kDa -0.60743
ZNF143 zinc finger protein 143 -0.60703
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.60687
CEP68 centrosomal protein 68kDa -0.60682
POLR1B polymerase (RNA) I polypeptide B, 128kDa -0.60615
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.60551
TMX2 thioredoxin-related transmembrane protein 2 -0.60287
PPP1R3D protein phosphatase 1, regulatory subunit 3D -0.60058
AFF1 AF4/FMR2 family, member 1 -0.59962
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.59906
ITSN2 intersectin 2 -0.59884
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -0.59822
C11ORF24 chromosome 11 open reading frame 24 -0.59805
METRN meteorin, glial cell differentiation regulator -0.598
RC3H2 ring finger and CCCH-type domains 2 -0.59758
HTATSF1 HIV-1 Tat specific factor 1 -0.5975
LEPROT leptin receptor overlapping transcript -0.59671
CASP3 caspase 3, apoptosis-related cysteine peptidase -0.59663
MELK maternal embryonic leucine zipper kinase -0.59577
PDGFC platelet derived growth factor C -0.59488
XK X-linked Kx blood group -0.59433
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.59433
SUSD5 sushi domain containing 5 -0.59424
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.59413
TES testin LIM domain protein -0.59391
PBRM1 polybromo 1 -0.59076
TAOK3 TAO kinase 3 -0.59049
ZMYM5 zinc finger, MYM-type 5 -0.59034
ZNF273 zinc finger protein 273 -0.59025
SNORA21 small nucleolar RNA, H/ACA box 21 -0.59008
NFE2L3 nuclear factor, erythroid 2-like 3 -0.58968
CLCN3 chloride channel, voltage-sensitive 3 -0.58874
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.58815
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -0.58704
IPO9 importin 9 -0.5865
POMP proteasome maturation protein -0.58647
NBEA neurobeachin -0.5853