Dataset | KnockTF Gene Expression Profiles with Transcription Factor Perturbations |
Category | transcriptomics |
Type | transcription factor perturbation |
Description | STAT3 siRNA knock from prostate cell line (KnockTF, DataSet_01_49) |
External Link | http://www.licpathway.net/KnockTF/search/search_sample_result.php?sample_id=DataSet_01_49 |
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200 genesdifferentially expressed following the STAT3_01_49 trascription factor perturbation from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
Symbol | Name | Standardized Value |
---|---|---|
TST | thiosulfate sulfurtransferase (rhodanese) | 5.14265 |
NME3 | NME/NM23 nucleoside diphosphate kinase 3 | 3.94901 |
TXNIP | thioredoxin interacting protein | 3.91415 |
IRF9 | interferon regulatory factor 9 | 3.80845 |
SERTAD3 | SERTA domain containing 3 | 3.76538 |
NINJ1 | ninjurin 1 | 3.75494 |
PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 3.69432 |
SDF2L1 | stromal cell-derived factor 2-like 1 | 3.68652 |
HIST1H1C | histone cluster 1, H1c | 3.67324 |
HIST3H2A | histone cluster 3, H2a | 3.65872 |
VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) | 3.59064 |
SCAND1 | SCAN domain containing 1 | 3.57557 |
RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | 3.5088 |
BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide | 3.48702 |
PLK1 | polo-like kinase 1 | 3.48626 |
PRR14 | proline rich 14 | 3.46354 |
PRRX2 | paired related homeobox 2 | 3.46293 |
IP6K2 | inositol hexakisphosphate kinase 2 | 3.46037 |
POMT1 | protein-O-mannosyltransferase 1 | 3.42514 |
PTGES | prostaglandin E synthase | 3.41492 |
ACOT8 | acyl-CoA thioesterase 8 | 3.37799 |
LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | 3.36417 |
LAGE3 | L antigen family, member 3 | 3.35016 |
ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | 3.28906 |
GPRC5C | G protein-coupled receptor, class C, group 5, member C | 3.2459 |
IL17RA | interleukin 17 receptor A | 3.22635 |
NT5C | 5', 3'-nucleotidase, cytosolic | 3.22625 |
EXOSC5 | exosome component 5 | 3.22415 |
DDIT3 | DNA-damage-inducible transcript 3 | 3.20014 |
PTGES2 | prostaglandin E synthase 2 | 3.19603 |
TIMP2 | TIMP metallopeptidase inhibitor 2 | 3.19097 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) | 3.18492 |
ABHD11 | abhydrolase domain containing 11 | 3.17738 |
AIP | aryl hydrocarbon receptor interacting protein | 3.17358 |
TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) | 3.13402 |
KIFC3 | kinesin family member C3 | 3.11042 |
HS1BP3 | HCLS1 binding protein 3 | 3.1007 |
SCAMP2 | secretory carrier membrane protein 2 | 3.10009 |
TRIB3 | tribbles pseudokinase 3 | 3.09309 |
MPST | mercaptopyruvate sulfurtransferase | 3.06514 |
TUSC2 | tumor suppressor candidate 2 | 3.03262 |
TPST1 | tyrosylprotein sulfotransferase 1 | 2.98937 |
RHOD | ras homolog family member D | 2.98044 |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 2.96472 |
TESC | tescalcin | 2.95304 |
DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 2.9517 |
NDUFA13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | 2.95031 |
ZMYM3 | zinc finger, MYM-type 3 | 2.94985 |
EGFL7 | EGF-like-domain, multiple 7 | 2.93785 |
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 2.93759 |
NMB | neuromedin B | 2.93515 |
TWF2 | twinfilin actin binding protein 2 | 2.93193 |
TMEM187 | transmembrane protein 187 | 2.93168 |
LCMT1 | leucine carboxyl methyltransferase 1 | 2.93158 |
POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.92544 |
AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 2.92191 |
SIRT2 | sirtuin 2 | 2.92129 |
NLRX1 | NLR family member X1 | 2.9028 |
SLC41A3 | solute carrier family 41, member 3 | 2.89933 |
PANK4 | pantothenate kinase 4 | 2.89056 |
OCEL1 | occludin/ELL domain containing 1 | 2.88331 |
ANAPC2 | anaphase promoting complex subunit 2 | 2.87425 |
ETFB | electron-transfer-flavoprotein, beta polypeptide | 2.85981 |
BAD | BCL2-associated agonist of cell death | 2.85445 |
MIIP | migration and invasion inhibitory protein | 2.85128 |
PNPLA6 | patatin-like phospholipase domain containing 6 | 2.83836 |
NAA10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit | 2.83414 |
ISG15 | ISG15 ubiquitin-like modifier | 2.83212 |
EPS8L2 | EPS8-like 2 | 2.82822 |
PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | 2.8231 |
OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 | 2.81989 |
SIPA1 | signal-induced proliferation-associated 1 | 2.81359 |
GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 2.81319 |
ISOC2 | isochorismatase domain containing 2 | 2.80303 |
CAPG | capping protein (actin filament), gelsolin-like | 2.77589 |
MLPH | melanophilin | 2.77308 |
COG4 | component of oligomeric golgi complex 4 | 2.75359 |
DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | 2.74312 |
CDA | cytidine deaminase | 2.73916 |
MPPE1 | metallophosphoesterase 1 | 2.73763 |
TCEA2 | transcription elongation factor A (SII), 2 | 2.73326 |
PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.72845 |
P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.7091 |
REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | 2.70514 |
EPHB4 | EPH receptor B4 | 2.70488 |
PMVK | phosphomevalonate kinase | 2.70229 |
CST3 | cystatin C | 2.69546 |
NAGK | N-acetylglucosamine kinase | 2.69511 |
CLK3 | CDC-like kinase 3 | 2.68736 |
ORAI3 | ORAI calcium release-activated calcium modulator 3 | 2.67668 |
TMEM161A | transmembrane protein 161A | 2.67298 |
TMEM106C | transmembrane protein 106C | 2.66728 |
ACADVL | acyl-CoA dehydrogenase, very long chain | 2.65996 |
ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 2.65733 |
LMAN2L | lectin, mannose-binding 2-like | 2.64752 |
TECR | trans-2,3-enoyl-CoA reductase | 2.64312 |
RABEPK | Rab9 effector protein with kelch motifs | 2.63377 |
DVL2 | dishevelled segment polarity protein 2 | 2.63357 |
GMPPA | GDP-mannose pyrophosphorylase A | 2.62635 |
ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 2.62567 |
Symbol | Name | Standardized Value |
---|---|---|
ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.65547 |
COX7B | cytochrome c oxidase subunit VIIb | -0.65174 |
SLC39A9 | solute carrier family 39, member 9 | -0.6517 |
CLGN | calmegin | -0.65098 |
HELZ | helicase with zinc finger | -0.64979 |
DROSHA | drosha, ribonuclease type III | -0.64952 |
SNX24 | sorting nexin 24 | -0.64937 |
GPHN | gephyrin | -0.64821 |
RPL27A | ribosomal protein L27a | -0.64747 |
ERH | enhancer of rudimentary homolog (Drosophila) | -0.64635 |
TBL2 | transducin (beta)-like 2 | -0.64622 |
SOX9 | SRY (sex determining region Y)-box 9 | -0.64428 |
ZNF432 | zinc finger protein 432 | -0.64426 |
CC2D1A | coiled-coil and C2 domain containing 1A | -0.64323 |
EML4 | echinoderm microtubule associated protein like 4 | -0.64317 |
HMGN2 | high mobility group nucleosomal binding domain 2 | -0.64203 |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.64139 |
SH2D4A | SH2 domain containing 4A | -0.64115 |
IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.64113 |
MKI67 | marker of proliferation Ki-67 | -0.6409 |
POMZP3 | POM121 and ZP3 fusion | -0.64016 |
NCOA6 | nuclear receptor coactivator 6 | -0.63902 |
TPST2 | tyrosylprotein sulfotransferase 2 | -0.63831 |
SMAD7 | SMAD family member 7 | -0.63806 |
STK4 | serine/threonine kinase 4 | -0.63659 |
PTK2 | protein tyrosine kinase 2 | -0.63599 |
ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.63598 |
POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.63586 |
EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.63429 |
ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.63374 |
ANAPC13 | anaphase promoting complex subunit 13 | -0.63289 |
NSL1 | NSL1, MIS12 kinetochore complex component | -0.63196 |
DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) | -0.63195 |
ELOVL5 | ELOVL fatty acid elongase 5 | -0.63182 |
PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.63139 |
KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -0.62919 |
ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | -0.62836 |
FBXW2 | F-box and WD repeat domain containing 2 | -0.62812 |
APH1A | APH1A gamma secretase subunit | -0.62792 |
MACF1 | microtubule-actin crosslinking factor 1 | -0.627 |
PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.62638 |
NOL11 | nucleolar protein 11 | -0.62505 |
ZNF587 | zinc finger protein 587 | -0.62483 |
PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta | -0.62479 |
MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | -0.62364 |
MED15 | mediator complex subunit 15 | -0.62141 |
PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | -0.61799 |
SPATA2L | spermatogenesis associated 2-like | -0.61715 |
NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | -0.61708 |
HHLA3 | HERV-H LTR-associating 3 | -0.61703 |
CLK4 | CDC-like kinase 4 | -0.61387 |
RPS7 | ribosomal protein S7 | -0.61384 |
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.6132 |
MAT2B | methionine adenosyltransferase II, beta | -0.61308 |
NUP205 | nucleoporin 205kDa | -0.61278 |
FBXL18 | F-box and leucine-rich repeat protein 18 | -0.61207 |
GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | -0.61192 |
ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.61176 |
ZNF85 | zinc finger protein 85 | -0.61104 |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.6106 |
FOXJ3 | forkhead box J3 | -0.60926 |
ZBED4 | zinc finger, BED-type containing 4 | -0.60804 |
ZNF814 | zinc finger protein 814 | -0.60746 |
NCBP2 | nuclear cap binding protein subunit 2, 20kDa | -0.60743 |
ZNF143 | zinc finger protein 143 | -0.60703 |
SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.60687 |
CEP68 | centrosomal protein 68kDa | -0.60682 |
POLR1B | polymerase (RNA) I polypeptide B, 128kDa | -0.60615 |
NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.60551 |
TMX2 | thioredoxin-related transmembrane protein 2 | -0.60287 |
PPP1R3D | protein phosphatase 1, regulatory subunit 3D | -0.60058 |
AFF1 | AF4/FMR2 family, member 1 | -0.59962 |
B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | -0.59906 |
ITSN2 | intersectin 2 | -0.59884 |
DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 | -0.59822 |
C11ORF24 | chromosome 11 open reading frame 24 | -0.59805 |
METRN | meteorin, glial cell differentiation regulator | -0.598 |
RC3H2 | ring finger and CCCH-type domains 2 | -0.59758 |
HTATSF1 | HIV-1 Tat specific factor 1 | -0.5975 |
LEPROT | leptin receptor overlapping transcript | -0.59671 |
CASP3 | caspase 3, apoptosis-related cysteine peptidase | -0.59663 |
MELK | maternal embryonic leucine zipper kinase | -0.59577 |
PDGFC | platelet derived growth factor C | -0.59488 |
XK | X-linked Kx blood group | -0.59433 |
MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.59433 |
SUSD5 | sushi domain containing 5 | -0.59424 |
VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.59413 |
TES | testin LIM domain protein | -0.59391 |
PBRM1 | polybromo 1 | -0.59076 |
TAOK3 | TAO kinase 3 | -0.59049 |
ZMYM5 | zinc finger, MYM-type 5 | -0.59034 |
ZNF273 | zinc finger protein 273 | -0.59025 |
SNORA21 | small nucleolar RNA, H/ACA box 21 | -0.59008 |
NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.58968 |
CLCN3 | chloride channel, voltage-sensitive 3 | -0.58874 |
NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -0.58815 |
TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -0.58704 |
IPO9 | importin 9 | -0.5865 |
POMP | proteasome maturation protein | -0.58647 |
NBEA | neurobeachin | -0.5853 |