| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | signal transducer and activator of transcription 5A|The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013] (NCBI Entrez Gene Database, 6776) |
| External Link | https://ncbi.nlm.nih.gov/gene/6776 |
| Similar Terms | |
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497 genes differentially expressed following the STAT5A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0312742 |
| CHEK2 | checkpoint kinase 2 | 0.0189078 |
| MAP7 | microtubule-associated protein 7 | 0.0141654 |
| C3 | complement component 3 | 0.0130482 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.0112979 |
| TSPAN8 | tetraspanin 8 | 0.0109662 |
| CLIC5 | chloride intracellular channel 5 | 0.0106573 |
| GATA6 | GATA binding protein 6 | 0.0104349 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.0103968 |
| ATF3 | activating transcription factor 3 | 0.010266 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0102195 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0100953 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.0100813 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00992936 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00969383 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00961547 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00922284 |
| EPCAM | epithelial cell adhesion molecule | 0.00901497 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00891963 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00859248 |
| KRT20 | keratin 20, type I | 0.00856826 |
| FABP1 | fatty acid binding protein 1, liver | 0.00842102 |
| THBS2 | thrombospondin 2 | 0.0083886 |
| HBB | hemoglobin, beta | 0.00832133 |
| NVL | nuclear VCP-like | 0.00822489 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00821333 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00821004 |
| NEBL | nebulette | 0.00816765 |
| CLDN8 | claudin 8 | 0.00811862 |
| S100A10 | S100 calcium binding protein A10 | 0.00803676 |
| C1S | complement component 1, s subcomponent | 0.00802477 |
| PLLP | plasmolipin | 0.00801854 |
| IFT52 | intraflagellar transport 52 | 0.0079979 |
| TSPAN1 | tetraspanin 1 | 0.0079546 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.00793876 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00793701 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00792433 |
| GPX2 | glutathione peroxidase 2 | 0.00790537 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00783176 |
| CSTA | cystatin A (stefin A) | 0.00782684 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.0078205 |
| PKP2 | plakophilin 2 | 0.00777167 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0077174 |
| SELENOW | selenoprotein W | 0.00768635 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0076642 |
| CCN2 | cellular communication network factor 2 | 0.00766242 |
| ATP10B | ATPase, class V, type 10B | 0.00765787 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00765425 |
| MYO6 | myosin VI | 0.00761233 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00758721 |
| KRCC1 | lysine-rich coiled-coil 1 | 0.00748729 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00747581 |
| IL1R1 | interleukin 1 receptor, type I | 0.00745812 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00745472 |
| LRRC19 | leucine rich repeat containing 19 | 0.00736427 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00736295 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00729733 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.0072956 |
| TMEM255A | transmembrane protein 255A | 0.00727801 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00725509 |
| NOX1 | NADPH oxidase 1 | 0.00719583 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.00719186 |
| CDC123 | cell division cycle 123 | 0.00717522 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00714561 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00712966 |
| CLCA4 | chloride channel accessory 4 | 0.00711625 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00710511 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | 0.00708143 |
| KRT19 | keratin 19, type I | 0.0070719 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0070692 |
| ABLIM1 | actin binding LIM protein 1 | 0.00706662 |
| GAS1 | growth arrest-specific 1 | 0.00706551 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00704057 |
| CLTB | clathrin, light chain B | 0.00702784 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00702581 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00699934 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 0.00699734 |
| FERMT1 | fermitin family member 1 | 0.0069236 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0069122 |
| VSNL1 | visinin-like 1 | 0.0068617 |
| LEFTY1 | left-right determination factor 1 | 0.00684218 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00682787 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00678677 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00676293 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00673238 |
| RGS13 | regulator of G-protein signaling 13 | 0.00670843 |
| ADD3 | adducin 3 (gamma) | 0.00667395 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00661279 |
| FDX1 | ferredoxin 1 | 0.00661072 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.00660591 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00658322 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00657729 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00657679 |
| ITM2C | integral membrane protein 2C | 0.00657677 |
| ODC1 | ornithine decarboxylase 1 | 0.00657524 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00656346 |
| THBS1 | thrombospondin 1 | 0.00656216 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.00655151 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.0065257 |
| MSLN | mesothelin | 0.0065238 |
| TRIM36 | tripartite motif containing 36 | 0.00651821 |
| SPAG6 | sperm associated antigen 6 | 0.00647092 |
| RNASET2 | ribonuclease T2 | 0.00645758 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00643789 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00641122 |
| ADRA2A | adrenoceptor alpha 2A | 0.00640372 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.0063988 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00639509 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | 0.00638048 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00637449 |
| OPTN | optineurin | 0.00633732 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00633443 |
| PRKD3 | protein kinase D3 | 0.00633206 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.00632484 |
| SHTN1 | shootin 1 | 0.00625569 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00625081 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00623577 |
| PMP2 | peripheral myelin protein 2 | 0.00622208 |
| DCHS1 | dachsous cadherin-related 1 | 0.00621726 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00620468 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 0.00620285 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00619381 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 | 0.00617235 |
| DCN | decorin | 0.00616063 |
| STMN2 | stathmin 2 | 0.00615378 |
| CHGB | chromogranin B | 0.00614549 |
| HSBP1 | heat shock factor binding protein 1 | 0.00613554 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00613153 |
| MFAP5 | microfibrillar associated protein 5 | 0.00612867 |
| ACYP2 | acylphosphatase 2, muscle type | 0.00608617 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00603838 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.00603467 |
| MAL | mal, T-cell differentiation protein | 0.00602964 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00602185 |
| ANO10 | anoctamin 10 | 0.00601886 |
| CCNG1 | cyclin G1 | 0.00601353 |
| CFAP298 | cilia and flagella associated protein 298 | 0.00600999 |
| AOC1 | amine oxidase, copper containing 1 | 0.00599595 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00599402 |
| SPAG1 | sperm associated antigen 1 | 0.00598019 |
| BTG2 | BTG family, member 2 | 0.00595756 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | 0.0059557 |
| MEN1 | multiple endocrine neoplasia I | 0.00594514 |
| DAXX | death-domain associated protein | 0.00593155 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00589193 |
| SPA17 | sperm autoantigenic protein 17 | 0.00588273 |
| ADM | adrenomedullin | 0.00586478 |
| E2F2 | E2F transcription factor 2 | 0.00585833 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00585315 |
| LUM | lumican | 0.00584559 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00582073 |
| ZG16 | zymogen granule protein 16 | 0.00581604 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | 0.00581557 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00579128 |
| RETREG1 | reticulophagy regulator 1 | 0.00579095 |
| RGS10 | regulator of G-protein signaling 10 | 0.00578007 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.00577642 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.00576105 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00573714 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00573097 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00572026 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.0057195 |
| PITX1 | paired-like homeodomain 1 | 0.00570573 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.00570492 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.00568047 |
| AQP8 | aquaporin 8 | 0.00567255 |
| TSPAN3 | tetraspanin 3 | 0.00567074 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00567072 |
| GUCY2C | guanylate cyclase 2C | 0.00566959 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | 0.00566884 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.0056683 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.00566824 |
| CAB39 | calcium binding protein 39 | 0.00565356 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | 0.00564358 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00564273 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00562622 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00560922 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00560772 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00558814 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00555502 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | 0.00555412 |
| STATH | statherin | 0.00554921 |
| STMN4 | stathmin-like 4 | 0.00554552 |
| COL10A1 | collagen, type X, alpha 1 | 0.00553291 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.00552814 |
| BTG3 | BTG family, member 3 | 0.00550084 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00549715 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00548907 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0054864 |
| VILL | villin-like | 0.00548484 |
| CYB5R4 | cytochrome b5 reductase 4 | 0.00548329 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.00548118 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.00546469 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00544809 |
| NANS | N-acetylneuraminic acid synthase | 0.00543243 |
| CLCA1 | chloride channel accessory 1 | 0.00542044 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00541609 |
| CALB2 | calbindin 2 | 0.00541024 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00539935 |
| HSPA12A | heat shock 70kDa protein 12A | 0.00539717 |
| ARHGAP44 | Rho GTPase activating protein 44 | 0.00538654 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00538094 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00535461 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00534907 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00534651 |
| ZBED8 | zinc finger, BED-type containing 8 | 0.00533929 |
| ASPN | asporin | 0.00533428 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00532928 |
| TEX10 | testis expressed 10 | 0.00532763 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.00532245 |
| MYOT | myotilin | 0.00531432 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.00529388 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.00529035 |
| C21ORF33 | chromosome 21 open reading frame 33 | 0.00526562 |
| NGRN | neugrin, neurite outgrowth associated | 0.005265 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00525669 |
| LMBRD1 | LMBR1 domain containing 1 | 0.00525315 |
| SHQ1 | SHQ1, H/ACA ribonucleoprotein assembly factor | 0.00525215 |
| LYZ | lysozyme | 0.00525176 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.00522871 |
| DTX4 | deltex 4, E3 ubiquitin ligase | 0.00520564 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00519679 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00517239 |
| FGFR4 | fibroblast growth factor receptor 4 | 0.00517084 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.00516336 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00513614 |
| ACVR2A | activin A receptor, type IIA | 0.00512909 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 0.00511919 |
| MATN2 | matrilin 2 | 0.00511543 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00510096 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00509691 |
| NLGN4X | neuroligin 4, X-linked | 0.00508636 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.0050808 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00507287 |
| TMEM9B | TMEM9 domain family, member B | 0.00507161 |
| MLF1 | myeloid leukemia factor 1 | 0.00506147 |
| KRT8 | keratin 8, type II | 0.00504861 |
| PIGR | polymeric immunoglobulin receptor | 0.00504695 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00504181 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.00503195 |
| PLCE1 | phospholipase C, epsilon 1 | 0.00502806 |
| RPA3 | replication protein A3, 14kDa | 0.00502363 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00501556 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00500627 |
| TASP1 | taspase, threonine aspartase, 1 | 0.00500542 |
| PPIF | peptidylprolyl isomerase F | 0.00499842 |
| GPX3 | glutathione peroxidase 3 | 0.00499172 |
| AK1 | adenylate kinase 1 | 0.00497012 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | 0.00496026 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 0.00495589 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.0169517 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0104153 |
| MXRA7 | matrix-remodelling associated 7 | -0.00989083 |
| BRD4 | bromodomain containing 4 | -0.00978433 |
| FASN | fatty acid synthase | -0.0097602 |
| IL2RB | interleukin 2 receptor, beta | -0.00955393 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00952193 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00949781 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00946919 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00937954 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00931811 |
| JMJD6 | jumonji domain containing 6 | -0.00931589 |
| GOLGA8A | golgin A8 family, member A | -0.00928742 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00910326 |
| PLBD1 | phospholipase B domain containing 1 | -0.00901 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00895269 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00895003 |
| FSTL1 | follistatin-like 1 | -0.00890039 |
| TPBG | trophoblast glycoprotein | -0.00870204 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00862222 |
| IFI44L | interferon-induced protein 44-like | -0.00856888 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00844364 |
| PCP4 | Purkinje cell protein 4 | -0.00835547 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00833587 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00825631 |
| TRIB2 | tribbles pseudokinase 2 | -0.00811691 |
| BCHE | butyrylcholinesterase | -0.00809153 |
| MGLL | monoglyceride lipase | -0.00806283 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00803494 |
| TLN1 | talin 1 | -0.00802459 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.0079412 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00793283 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00788358 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00783052 |
| RUBCN | rubicon autophagy regulator | -0.00781082 |
| AGRN | agrin | -0.00775786 |
| ZNF586 | zinc finger protein 586 | -0.00771686 |
| NADK | NAD kinase | -0.00770961 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0076281 |
| CCL13 | chemokine (C-C motif) ligand 13 | -0.0076193 |
| ACTN4 | actinin, alpha 4 | -0.00758887 |
| DMXL2 | Dmx-like 2 | -0.00757182 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00750023 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00748319 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00745303 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.0073663 |
| DVL1 | dishevelled segment polarity protein 1 | -0.00735972 |
| HOXB2 | homeobox B2 | -0.00734433 |
| CCNL2 | cyclin L2 | -0.00733442 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00722553 |
| EXOC7 | exocyst complex component 7 | -0.00717846 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00714677 |
| KPNB1 | karyopherin (importin) beta 1 | -0.00705458 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00703912 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00701929 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00701309 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.00700777 |
| SDC3 | syndecan 3 | -0.0069999 |
| SIRT3 | sirtuin 3 | -0.00698436 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0069733 |
| HOPX | HOP homeobox | -0.00696139 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.0069388 |
| IFI44 | interferon-induced protein 44 | -0.00692733 |
| RTL8C | retrotransposon Gag like 8C | -0.00690692 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00688893 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00685779 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00685703 |
| XIC | X chromosome inactivation center | -0.00684016 |
| HCP5 | HLA complex P5 (non-protein coding) | -0.00683238 |
| NXN | nucleoredoxin | -0.00676397 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.0067567 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00674412 |
| MRTFB | myocardin related transcription factor B | -0.00671477 |
| MMP2 | matrix metallopeptidase 2 | -0.00670884 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.0066978 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.0066972 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | -0.00665918 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00665568 |
| PDGFC | platelet derived growth factor C | -0.00665097 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00664612 |
| USP32P2 | ubiquitin specific peptidase 32 pseudogene 2 | -0.00660284 |
| TNS1 | tensin 1 | -0.00658175 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00657829 |
| SYNGR3 | synaptogyrin 3 | -0.00657523 |
| GLUL | glutamate-ammonia ligase | -0.00657074 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00654385 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00654075 |
| APOD | apolipoprotein D | -0.00649444 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.00648954 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00648502 |
| SMAD7 | SMAD family member 7 | -0.00648428 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00647807 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00645938 |
| STC2 | stanniocalcin 2 | -0.00641857 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00641243 |
| TLE4 | transducin-like enhancer of split 4 | -0.00640523 |
| MECP2 | methyl CpG binding protein 2 | -0.00639944 |
| KIF20A | kinesin family member 20A | -0.00638676 |
| XAF1 | XIAP associated factor 1 | -0.00634711 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.0063419 |
| FBN2 | fibrillin 2 | -0.00632213 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00630078 |
| KRT1 | keratin 1, type II | -0.00629308 |
| CD209 | CD209 molecule | -0.00629024 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00628567 |
| CDK19 | cyclin-dependent kinase 19 | -0.00627968 |
| CSAD | cysteine sulfinic acid decarboxylase | -0.00620952 |
| TSPAN5 | tetraspanin 5 | -0.00617594 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.00611947 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00611204 |
| MED13 | mediator complex subunit 13 | -0.00611112 |
| PRF1 | perforin 1 (pore forming protein) | -0.0061004 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00607668 |
| DESI1 | desumoylating isopeptidase 1 | -0.00605126 |
| FBXW2 | F-box and WD repeat domain containing 2 | -0.0060491 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00604858 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | -0.00604364 |
| G0S2 | G0/G1 switch 2 | -0.00603439 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00601885 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00601091 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00600482 |
| LOXL2 | lysyl oxidase-like 2 | -0.0059995 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00598094 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0059603 |
| WIZ | widely interspaced zinc finger motifs | -0.00595811 |
| VCL | vinculin | -0.00595604 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00595461 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00593198 |
| COLEC12 | collectin sub-family member 12 | -0.00592833 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00591389 |
| FGL2 | fibrinogen-like 2 | -0.00589003 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00587989 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00587267 |
| MINK1 | misshapen-like kinase 1 | -0.0058627 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00583528 |
| OTUD3 | OTU deubiquitinase 3 | -0.00583252 |
| PLPP3 | phospholipid phosphatase 3 | -0.00582708 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00581845 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | -0.00581536 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0058107 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00580987 |
| MAML1 | mastermind-like 1 (Drosophila) | -0.00580896 |
| SETD5 | SET domain containing 5 | -0.00579184 |
| MLPH | melanophilin | -0.00577747 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0057741 |
| CNN3 | calponin 3, acidic | -0.00575555 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -0.0057483 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00574481 |
| CAV2 | caveolin 2 | -0.00574439 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -0.00573038 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | -0.00572285 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | -0.00571501 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00570332 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00569457 |
| HIC2 | hypermethylated in cancer 2 | -0.00568714 |
| USP48 | ubiquitin specific peptidase 48 | -0.00567813 |
| EVA1B | eva-1 homolog B (C. elegans) | -0.00567437 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0056733 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00566094 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0056431 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.00562578 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00561651 |
| IL11RA | interleukin 11 receptor, alpha | -0.0056066 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00560075 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00559723 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00558198 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00557317 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00556121 |
| CANT1 | calcium activated nucleotidase 1 | -0.00553684 |
| ACTN1 | actinin, alpha 1 | -0.00553532 |
| HMG20B | high mobility group 20B | -0.00552821 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00551503 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0055092 |
| TATDN2 | TatD DNase domain containing 2 | -0.00549979 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00549919 |
| CBX1 | chromobox homolog 1 | -0.00549854 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | -0.00549596 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00549509 |
| MNT | MAX network transcriptional repressor | -0.00548724 |
| NUP210 | nucleoporin 210kDa | -0.00547326 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma | -0.0054723 |
| TP73-AS1 | TP73 antisense RNA 1 | -0.00547034 |
| S100A9 | S100 calcium binding protein A9 | -0.00546989 |
| LAMA5 | laminin, alpha 5 | -0.00546233 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00545878 |
| INHBB | inhibin, beta B | -0.00544306 |
| PELO | pelota homolog (Drosophila) | -0.00544037 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.00543377 |
| PRKCB | protein kinase C, beta | -0.0054325 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.00540311 |
| PFN2 | profilin 2 | -0.00539975 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00539497 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00539455 |
| KRT2 | keratin 2, type II | -0.00538908 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00538858 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.0053511 |
| AMOTL2 | angiomotin like 2 | -0.00534761 |
| RXRA | retinoid X receptor, alpha | -0.00534192 |
| IRS2 | insulin receptor substrate 2 | -0.0053397 |
| RHOB | ras homolog family member B | -0.00533238 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.00533189 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00532775 |
| S100A2 | S100 calcium binding protein A2 | -0.00532723 |
| CCL17 | chemokine (C-C motif) ligand 17 | -0.00530034 |
| REX1BD | required for excision 1-B domain containing | -0.00529951 |
| SETBP1 | SET binding protein 1 | -0.00528582 |
| ELP1 | elongator acetyltransferase complex subunit 1 | -0.00528508 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -0.00527955 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.0052719 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00525383 |
| F2R | coagulation factor II (thrombin) receptor | -0.00522514 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00521387 |
| IRF4 | interferon regulatory factor 4 | -0.00521224 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00521176 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00521046 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 | -0.00520879 |
| WWC3 | WWC family member 3 | -0.00520409 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.00520023 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | -0.00519345 |
| ETV5 | ets variant 5 | -0.00518666 |
| CD84 | CD84 molecule | -0.00518334 |
| RETREG2 | reticulophagy regulator family member 2 | -0.00517411 |
| TYMS | thymidylate synthetase | -0.0051711 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0051693 |
| LRRC47 | leucine rich repeat containing 47 | -0.00516768 |
| RBL2 | retinoblastoma-like 2 | -0.00516637 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00515932 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0051583 |
| IRF7 | interferon regulatory factor 7 | -0.00514899 |
| NOTCH3 | notch 3 | -0.00513775 |
| ADRB2 | adrenoceptor beta 2, surface | -0.00513175 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | -0.00512994 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | -0.00512226 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.00512213 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00511267 |
| KHSRP | KH-type splicing regulatory protein | -0.00510458 |
| DNM1 | dynamin 1 | -0.00509141 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00508823 |
| TSKU | tsukushi, small leucine rich proteoglycan | -0.00508544 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00508025 |
| DENND4B | DENN/MADD domain containing 4B | -0.00507931 |
| NID1 | nidogen 1 | -0.00507325 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00507175 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00506766 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00505358 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00503537 |
| TCF4 | transcription factor 4 | -0.00501045 |
