| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | signal transducer and activator of transcription 6, interleukin-4 induced|The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 6778) |
| External Link | https://ncbi.nlm.nih.gov/gene/6778 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the STAT6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 0.0164762 |
| MAGEA3 | melanoma antigen family A3 | 0.0160172 |
| RTN2 | reticulon 2 | 0.0158511 |
| FCGBP | Fc fragment of IgG binding protein | 0.0157404 |
| ADI1 | acireductone dioxygenase 1 | 0.0143702 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.0143699 |
| PEG3 | paternally expressed 3 | 0.0141871 |
| FABP7 | fatty acid binding protein 7, brain | 0.0140217 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.013208 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0128836 |
| MYBPC1 | myosin binding protein C, slow type | 0.012847 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0127611 |
| TSPAN8 | tetraspanin 8 | 0.0126316 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0125304 |
| ASS1 | argininosuccinate synthase 1 | 0.0125144 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0122757 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0121291 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0119387 |
| ATF3 | activating transcription factor 3 | 0.0115715 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0114491 |
| SLN | sarcolipin | 0.0111499 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0108509 |
| ZIC1 | Zic family member 1 | 0.0105154 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.0103876 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0103579 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0102774 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0101792 |
| TNNC1 | troponin C type 1 (slow) | 0.010085 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00997569 |
| PENK | proenkephalin | 0.00991949 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00991938 |
| KLHL41 | kelch-like family member 41 | 0.00989986 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00988614 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.0098276 |
| H1-2 | H1.2 linker histone, cluster member | 0.00972427 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00959321 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00958702 |
| TTN | titin | 0.0095017 |
| DCN | decorin | 0.0094234 |
| MAGEA12 | melanoma antigen family A12 | 0.00941222 |
| MB | myoglobin | 0.00935519 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00932264 |
| PLP1 | proteolipid protein 1 | 0.0092283 |
| ANXA6 | annexin A6 | 0.00920508 |
| ADD3 | adducin 3 (gamma) | 0.00919543 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0091415 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0091077 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00901291 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00875827 |
| CKM | creatine kinase, muscle | 0.00872424 |
| NRCAM | neuronal cell adhesion molecule | 0.00865238 |
| EGR3 | early growth response 3 | 0.00861506 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00851158 |
| SGCE | sarcoglycan, epsilon | 0.00848315 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0084088 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00840588 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00834832 |
| MYOT | myotilin | 0.00834706 |
| DOK5 | docking protein 5 | 0.00830286 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00822888 |
| PUDP | pseudouridine 5'-phosphatase | 0.00821492 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00819813 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00818494 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00817704 |
| S100P | S100 calcium binding protein P | 0.0081751 |
| COQ8A | coenzyme Q8A | 0.00816409 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00808949 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0079727 |
| CD99 | CD99 molecule | 0.00793544 |
| THBS1 | thrombospondin 1 | 0.00788259 |
| LUM | lumican | 0.00780467 |
| ABHD6 | abhydrolase domain containing 6 | 0.00779961 |
| TRIB2 | tribbles pseudokinase 2 | 0.00779846 |
| EMP2 | epithelial membrane protein 2 | 0.00778452 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00778242 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00771552 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00770904 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00768928 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00763557 |
| NPTX2 | neuronal pentraxin II | 0.00762934 |
| CYTL1 | cytokine-like 1 | 0.00758271 |
| STAP2 | signal transducing adaptor family member 2 | 0.00757773 |
| MAGEA1 | melanoma antigen family A1 | 0.0075725 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00754744 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0075346 |
| S100B | S100 calcium binding protein B | 0.00751721 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00745224 |
| KRT19 | keratin 19, type I | 0.00744249 |
| ANK2 | ankyrin 2, neuronal | 0.00742142 |
| ITM2A | integral membrane protein 2A | 0.007383 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00737258 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00736271 |
| DCT | dopachrome tautomerase | 0.0073154 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00730043 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00729662 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00727538 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00723935 |
| PSCA | prostate stem cell antigen | 0.00722583 |
| GAS1 | growth arrest-specific 1 | 0.00720756 |
| PODXL | podocalyxin-like | 0.00718328 |
| AK1 | adenylate kinase 1 | 0.00713959 |
| DCHS1 | dachsous cadherin-related 1 | 0.00710822 |
| MYOZ2 | myozenin 2 | 0.0071052 |
| METTL7A | methyltransferase like 7A | 0.00708546 |
| FRZB | frizzled-related protein | 0.00705204 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00704525 |
| AOX1 | aldehyde oxidase 1 | 0.00703643 |
| ACTN2 | actinin, alpha 2 | 0.00703505 |
| TNNC2 | troponin C type 2 (fast) | 0.00701368 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00699807 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.0069909 |
| CFI | complement factor I | 0.00698986 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00697633 |
| FBLN5 | fibulin 5 | 0.0069661 |
| THBS4 | thrombospondin 4 | 0.00696061 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00695283 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00693983 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00688713 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00685262 |
| CFH | complement factor H | 0.00682302 |
| CRYAB | crystallin, alpha B | 0.00682035 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00680906 |
| BIN1 | bridging integrator 1 | 0.00679653 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00679645 |
| PMP2 | peripheral myelin protein 2 | 0.00677977 |
| C1R | complement component 1, r subcomponent | 0.00677822 |
| NID1 | nidogen 1 | 0.0067643 |
| TMOD1 | tropomodulin 1 | 0.00674577 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00673855 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00671826 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00670845 |
| NLGN4X | neuroligin 4, X-linked | 0.00668599 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00668514 |
| JAM3 | junctional adhesion molecule 3 | 0.00667919 |
| GAP43 | growth associated protein 43 | 0.00667259 |
| C1S | complement component 1, s subcomponent | 0.00667044 |
| OLFML3 | olfactomedin-like 3 | 0.00665962 |
| TFF1 | trefoil factor 1 | 0.00662079 |
| AHSG | alpha-2-HS-glycoprotein | 0.00661724 |
| PEG10 | paternally expressed 10 | 0.00661058 |
| STMN2 | stathmin 2 | 0.00660894 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00660247 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00657581 |
| C3 | complement component 3 | 0.00657551 |
| PLLP | plasmolipin | 0.00656009 |
| LAMA2 | laminin, alpha 2 | 0.00655828 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00655767 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00655688 |
| MIA | melanoma inhibitory activity | 0.00654208 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00652783 |
| OGN | osteoglycin | 0.00649111 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00649 |
| APOA2 | apolipoprotein A-II | 0.00646494 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00645612 |
| COLEC12 | collectin sub-family member 12 | 0.00643911 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0064372 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00643681 |
| FABP1 | fatty acid binding protein 1, liver | 0.00643531 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00643486 |
| REEP1 | receptor accessory protein 1 | 0.00641177 |
| DMD | dystrophin | 0.00640168 |
| GPX1 | glutathione peroxidase 1 | 0.00639984 |
| SELENOW | selenoprotein W | 0.00639135 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.0063814 |
| MT1M | metallothionein 1M | 0.00637966 |
| L1CAM | L1 cell adhesion molecule | 0.00636761 |
| C7 | complement component 7 | 0.00636354 |
| COG2 | component of oligomeric golgi complex 2 | 0.0063316 |
| TPM3 | tropomyosin 3 | 0.00632662 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 | 0.00626981 |
| FMO1 | flavin containing monooxygenase 1 | 0.00625567 |
| COLEC11 | collectin sub-family member 11 | 0.00624771 |
| EMP1 | epithelial membrane protein 1 | 0.00624645 |
| MYBPC2 | myosin binding protein C, fast type | 0.0062447 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00623154 |
| LAMB1 | laminin, beta 1 | 0.00622295 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | 0.00621307 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | 0.00620844 |
| GPM6B | glycoprotein M6B | 0.00620812 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.0061721 |
| WDR61 | WD repeat domain 61 | 0.00613602 |
| TMEM100 | transmembrane protein 100 | 0.00613222 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00611245 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00609191 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00608965 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 0.00607314 |
| PROM1 | prominin 1 | 0.00605116 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00601148 |
| ENO3 | enolase 3 (beta, muscle) | 0.00600884 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.00600123 |
| NRN1 | neuritin 1 | 0.00598632 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00597926 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 0.00597574 |
| LDB3 | LIM domain binding 3 | 0.00597514 |
| APOD | apolipoprotein D | 0.00597452 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00597206 |
| SMPX | small muscle protein, X-linked | 0.00594976 |
| SSPN | sarcospan | 0.00594554 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00593901 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.00591026 |
| KLF2 | Kruppel-like factor 2 | 0.00586593 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00586207 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00586049 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00580812 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00580362 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00578929 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00578245 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00576818 |
| GPC3 | glypican 3 | 0.0057565 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00575589 |
| H1-10 | H1.10 linker histone | 0.00572561 |
| COPS7A | COP9 signalosome subunit 7A | 0.00569501 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.00568103 |
| PLCE1 | phospholipase C, epsilon 1 | 0.00566243 |
| TYRP1 | tyrosinase-related protein 1 | 0.00565018 |
| IL17RB | interleukin 17 receptor B | 0.00564686 |
| KRT15 | keratin 15, type I | 0.00564053 |
| MAL | mal, T-cell differentiation protein | 0.00559992 |
| PITX3 | paired-like homeodomain 3 | 0.00559506 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00558776 |
| CLCA4 | chloride channel accessory 4 | 0.00557771 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00555837 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00555683 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00555283 |
| MT3 | metallothionein 3 | 0.00554239 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.00552993 |
| SDF4 | stromal cell derived factor 4 | 0.00551662 |
| IQCG | IQ motif containing G | 0.00549883 |
| RPA2 | replication protein A2, 32kDa | 0.00547108 |
| KLK11 | kallikrein-related peptidase 11 | 0.00546837 |
| LIMA1 | LIM domain and actin binding 1 | 0.0054605 |
| MYO1C | myosin IC | 0.0054508 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00543087 |
| LRRC17 | leucine rich repeat containing 17 | 0.00542375 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00541902 |
| PLSCR4 | phospholipid scramblase 4 | 0.005408 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00540777 |
| SHOX2 | short stature homeobox 2 | 0.00540126 |
| SECTM1 | secreted and transmembrane 1 | 0.00539056 |
| USP11 | ubiquitin specific peptidase 11 | 0.00538882 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00537711 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00534237 |
| FMOD | fibromodulin | 0.00531916 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00529466 |
| AGR2 | anterior gradient 2 | 0.00527639 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 0.00527225 |
| RELN | reelin | 0.00526958 |
| NES | nestin | 0.00525944 |
| SOD3 | superoxide dismutase 3, extracellular | 0.00525666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0155648 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.0131072 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.013053 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0123614 |
| CSTA | cystatin A (stefin A) | -0.0106182 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.0105647 |
| LYZ | lysozyme | -0.00983897 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00963918 |
| FYB1 | FYN binding protein 1 | -0.00929539 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00919604 |
| SFN | stratifin | -0.0090276 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00891082 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00890111 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0086849 |
| AIM2 | absent in melanoma 2 | -0.00868464 |
| TLR2 | toll-like receptor 2 | -0.00866047 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00831126 |
| WT1 | Wilms tumor 1 | -0.00827469 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00821074 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00819594 |
| ABHD4 | abhydrolase domain containing 4 | -0.00810383 |
| CUX1 | cut-like homeobox 1 | -0.00799174 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00797591 |
| KRT6A | keratin 6A, type II | -0.007967 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00768511 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00765013 |
| SIRT3 | sirtuin 3 | -0.00763711 |
| TNC | tenascin C | -0.00751072 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0074883 |
| SFTPC | surfactant protein C | -0.00740256 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00730456 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00722969 |
| CHIT1 | chitinase 1 (chitotriosidase) | -0.00722809 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00720832 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00720313 |
| ELANE | elastase, neutrophil expressed | -0.00719146 |
| PCP4 | Purkinje cell protein 4 | -0.00717135 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00713603 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00711359 |
| RASA4 | RAS p21 protein activator 4 | -0.00708679 |
| S100A12 | S100 calcium binding protein A12 | -0.00707772 |
| MMP9 | matrix metallopeptidase 9 | -0.00703812 |
| GAB2 | GRB2-associated binding protein 2 | -0.00702898 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00700614 |
| FBN2 | fibrillin 2 | -0.00698623 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00690619 |
| CAMP | cathelicidin antimicrobial peptide | -0.00689355 |
| TGM2 | transglutaminase 2 | -0.00687049 |
| CTBP2 | C-terminal binding protein 2 | -0.00685116 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00681515 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00680776 |
| AZU1 | azurocidin 1 | -0.00675264 |
| BLNK | B-cell linker | -0.00671213 |
| SIRPA | signal-regulatory protein alpha | -0.00670509 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | -0.00669091 |
| ZNF589 | zinc finger protein 589 | -0.00667544 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00666315 |
| NVL | nuclear VCP-like | -0.00664938 |
| STK26 | serine/threonine protein kinase 26 | -0.00655277 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.00653786 |
| S100A2 | S100 calcium binding protein A2 | -0.00653012 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00651052 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00650879 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0063809 |
| HYOU1 | hypoxia up-regulated 1 | -0.0063713 |
| PNN | pinin, desmosome associated protein | -0.00637024 |
| FZD5 | frizzled class receptor 5 | -0.00633161 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00628257 |
| THOC2 | THO complex 2 | -0.00626857 |
| PLXNC1 | plexin C1 | -0.00624093 |
| PLEK | pleckstrin | -0.00624026 |
| ESR1 | estrogen receptor 1 | -0.00622494 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.0061579 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00608904 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00607897 |
| CD2 | CD2 molecule | -0.00604906 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00603402 |
| BID | BH3 interacting domain death agonist | -0.00603319 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00602481 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00599522 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.00599049 |
| SELL | selectin L | -0.00591846 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00591051 |
| TFEC | transcription factor EC | -0.00589312 |
| FNBP1L | formin binding protein 1-like | -0.00588656 |
| DACH1 | dachshund family transcription factor 1 | -0.00587813 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.00584629 |
| MCOLN1 | mucolipin 1 | -0.00577828 |
| SEC61B | Sec61 beta subunit | -0.00577124 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.00576165 |
| RAB32 | RAB32, member RAS oncogene family | -0.0057469 |
| PHIP | pleckstrin homology domain interacting protein | -0.00573696 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00573214 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00572931 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00571517 |
| VWF | von Willebrand factor | -0.00570839 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.00570669 |
| MICALL1 | MICAL-like 1 | -0.00569009 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -0.00567002 |
| RAB3B | RAB3B, member RAS oncogene family | -0.00566887 |
| NUP107 | nucleoporin 107kDa | -0.00566511 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00561639 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -0.0056145 |
| PLAU | plasminogen activator, urokinase | -0.00561007 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.0056097 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00558205 |
| RBM25 | RNA binding motif protein 25 | -0.00557048 |
| VEGFA | vascular endothelial growth factor A | -0.00556646 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.00556534 |
| SPART | spartin | -0.00554271 |
| MYRF | myelin regulatory factor | -0.00553752 |
| KIF14 | kinesin family member 14 | -0.00551847 |
| SLAMF7 | SLAM family member 7 | -0.00551407 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | -0.00550672 |
| DEFB1 | defensin, beta 1 | -0.0054935 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00548777 |
| CD200 | CD200 molecule | -0.00548605 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00547901 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00547512 |
| JMJD1C | jumonji domain containing 1C | -0.00546681 |
| PDGFC | platelet derived growth factor C | -0.00544952 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00543317 |
| MAP7 | microtubule-associated protein 7 | -0.00542215 |
| RGS5 | regulator of G-protein signaling 5 | -0.00540959 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00540804 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00540186 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00539429 |
| MED13 | mediator complex subunit 13 | -0.00538734 |
| SPRR1B | small proline-rich protein 1B | -0.00537259 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00536862 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00535614 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00533562 |
| EMX2 | empty spiracles homeobox 2 | -0.00532804 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00532625 |
| LTA4H | leukotriene A4 hydrolase | -0.00532284 |
| MTF2 | metal response element binding transcription factor 2 | -0.00530298 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | -0.00526496 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00517819 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.00515265 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00512882 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00511923 |
| RNF130 | ring finger protein 130 | -0.00511291 |
| MIS18BP1 | MIS18 binding protein 1 | -0.00511026 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00510871 |
| TLE4 | transducin-like enhancer of split 4 | -0.00510859 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -0.00510661 |
| PTHLH | parathyroid hormone-like hormone | -0.00507902 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00507651 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.00506811 |
| GPR183 | G protein-coupled receptor 183 | -0.00506293 |
| CST7 | cystatin F (leukocystatin) | -0.00506005 |
| MPO | myeloperoxidase | -0.00505874 |
| CORO1C | coronin, actin binding protein, 1C | -0.00505737 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00505518 |
| BTG3 | BTG family, member 3 | -0.00505329 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | -0.00505063 |
| REG1A | regenerating islet-derived 1 alpha | -0.00504455 |
| ZNF652 | zinc finger protein 652 | -0.00503705 |
| KDR | kinase insert domain receptor | -0.00502699 |
| S100A9 | S100 calcium binding protein A9 | -0.0050179 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00501353 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.00500398 |
| RBM26 | RNA binding motif protein 26 | -0.00497835 |
| POU2F1 | POU class 2 homeobox 1 | -0.00495844 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00494088 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00493081 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00492962 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00491692 |
| TMEM63A | transmembrane protein 63A | -0.00491288 |
| GGCT | gamma-glutamylcyclotransferase | -0.00491142 |
| PLXNB1 | plexin B1 | -0.00490855 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00489582 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0048861 |
| SHTN1 | shootin 1 | -0.00484185 |
| PF4 | platelet factor 4 | -0.00483938 |
| GAL3ST1 | galactose-3-O-sulfotransferase 1 | -0.00483488 |
| RAPSN | receptor-associated protein of the synapse | -0.00483305 |
| RIT1 | Ras-like without CAAX 1 | -0.00481785 |
| ACTN1 | actinin, alpha 1 | -0.00481275 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00479271 |
| GPATCH8 | G patch domain containing 8 | -0.00478923 |
| ZNF430 | zinc finger protein 430 | -0.00478219 |
| TMEM131 | transmembrane protein 131 | -0.00478036 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00477779 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00477418 |
| KRT18 | keratin 18, type I | -0.00476993 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00475162 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00473009 |
| RTN1 | reticulon 1 | -0.004727 |
| STX3 | syntaxin 3 | -0.00471881 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00471838 |
| SLAMF8 | SLAM family member 8 | -0.00470089 |
| SFTPA2 | surfactant protein A2 | -0.00469913 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00467411 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00467145 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00466713 |
| USP25 | ubiquitin specific peptidase 25 | -0.00466188 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.00466109 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00465254 |
| FPR3 | formyl peptide receptor 3 | -0.00464596 |
| KLF13 | Kruppel-like factor 13 | -0.00462862 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.00462675 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00462165 |
| CD151 | CD151 molecule (Raph blood group) | -0.004621 |
| JADE1 | jade family PHD finger 1 | -0.00461198 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00460219 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00459688 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00459654 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00459389 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00459163 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00459114 |
| PKP4 | plakophilin 4 | -0.00458124 |
| PUM1 | pumilio RNA-binding family member 1 | -0.00457246 |
| NAGK | N-acetylglucosamine kinase | -0.00455293 |
| CYTIP | cytohesin 1 interacting protein | -0.00454345 |
| REV1 | REV1, polymerase (DNA directed) | -0.00452767 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00452283 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00452158 |
| STK39 | serine threonine kinase 39 | -0.00450661 |
| ZNF721 | zinc finger protein 721 | -0.00450569 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00450219 |
| RBM4 | RNA binding motif protein 4 | -0.00449936 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00449835 |
| SACS | sacsin molecular chaperone | -0.00449549 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00449248 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00448752 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00448337 |
| CCDC92 | coiled-coil domain containing 92 | -0.00447932 |
| CERS6 | ceramide synthase 6 | -0.00446277 |
| RESF1 | retroelement silencing factor 1 | -0.00445204 |
| HAL | histidine ammonia-lyase | -0.00444734 |
| CTSG | cathepsin G | -0.00444537 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00444439 |
| RRBP1 | ribosome binding protein 1 | -0.00444347 |
| RSF1 | remodeling and spacing factor 1 | -0.00444335 |
| PFKL | phosphofructokinase, liver | -0.00444291 |
| ANO10 | anoctamin 10 | -0.0044417 |
| RGS13 | regulator of G-protein signaling 13 | -0.00443692 |
| TUT4 | terminal uridylyl transferase 4 | -0.00442672 |
| POU5F1P3 | POU class 5 homeobox 1 pseudogene 3 | -0.00442624 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.00442061 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.00441919 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.00441859 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00440907 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -0.00440833 |
| FEM1B | fem-1 homolog b (C. elegans) | -0.00440575 |
| SFTPD | surfactant protein D | -0.00440313 |
| SEC61G | Sec61 gamma subunit | -0.0043999 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.00438856 |
