STK11 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description serine/threonine kinase 11|This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6794)
External Link https://ncbi.nlm.nih.gov/gene/6794
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Genes

500 genes differentially expressed following the STK11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IGFBP5 insulin-like growth factor binding protein 5 0.0141515
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.0137568
TFF1 trefoil factor 1 0.0135888
EIF5A eukaryotic translation initiation factor 5A 0.0123756
S100A9 S100 calcium binding protein A9 0.012258
GJA1 gap junction protein, alpha 1, 43kDa 0.0122142
CFD complement factor D (adipsin) 0.0119773
IFI6 interferon, alpha-inducible protein 6 0.0116718
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.0116248
ADIRF adipogenesis regulatory factor 0.0115278
CRIP1 cysteine-rich protein 1 (intestinal) 0.0114661
CD200 CD200 molecule 0.010452
SLPI secretory leukocyte peptidase inhibitor 0.0102704
LMO2 LIM domain only 2 (rhombotin-like 1) 0.010088
CA12 carbonic anhydrase XII 0.0100732
LTF lactotransferrin 0.0100123
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00996175
SCGB1D2 secretoglobin, family 1D, member 2 0.00986836
LEF1 lymphoid enhancer-binding factor 1 0.0098136
SPARCL1 SPARC-like 1 (hevin) 0.00969439
CA2 carbonic anhydrase II 0.00953346
TFF3 trefoil factor 3 (intestinal) 0.00948719
CSTA cystatin A (stefin A) 0.00947573
S100A8 S100 calcium binding protein A8 0.00937347
RGS5 regulator of G-protein signaling 5 0.00925107
CSRP2 cysteine and glycine-rich protein 2 0.00923874
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00919482
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00906674
CLDN7 claudin 7 0.00902206
G0S2 G0/G1 switch 2 0.00899932
SFRP1 secreted frizzled-related protein 1 0.00887771
CDC42 cell division cycle 42 0.00887291
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00882395
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00874328
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00866257
NUTF2 nuclear transport factor 2 0.00857558
PCOLCE procollagen C-endopeptidase enhancer 0.00843272
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00841393
HSPB8 heat shock 22kDa protein 8 0.00840226
METTL7A methyltransferase like 7A 0.00838478
WFDC2 WAP four-disulfide core domain 2 0.00838273
NELL1 NEL-like 1 (chicken) 0.00837997
LCN2 lipocalin 2 0.00835233
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00829062
PRAME preferentially expressed antigen in melanoma 0.00828658
PDZRN3 PDZ domain containing ring finger 3 0.00828012
STC1 stanniocalcin 1 0.008248
GREB1 growth regulation by estrogen in breast cancer 1 0.00822147
S100A7 S100 calcium binding protein A7 0.0081986
HIRA histone cell cycle regulator 0.00818586
LMNB1 lamin B1 0.00813311
TBX3 T-box 3 0.00812064
TRH thyrotropin-releasing hormone 0.00809625
TACSTD2 tumor-associated calcium signal transducer 2 0.00806269
PDE4B phosphodiesterase 4B, cAMP-specific 0.00803267
IL1RN interleukin 1 receptor antagonist 0.0079673
SCGB2A1 secretoglobin, family 2A, member 1 0.00795361
MGP matrix Gla protein 0.00793319
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.00788507
CANX calnexin 0.00788342
FABP4 fatty acid binding protein 4, adipocyte 0.00783013
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.0078288
SCGB2A2 secretoglobin, family 2A, member 2 0.00782508
HOXC6 homeobox C6 0.00778283
BHLHE41 basic helix-loop-helix family, member e41 0.00777075
CRABP2 cellular retinoic acid binding protein 2 0.00773926
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00772502
CD93 CD93 molecule 0.00771434
ELANE elastase, neutrophil expressed 0.00769347
SSPN sarcospan 0.00766943
FKBP4 FK506 binding protein 4, 59kDa 0.00765961
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00765716
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.0076288
ANO1 anoctamin 1, calcium activated chloride channel 0.00762496
COL14A1 collagen, type XIV, alpha 1 0.00757085
JUP junction plakoglobin 0.00752693
CXCL8 chemokine (C-X-C motif) ligand 8 0.00750798
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0074871
TSPAN7 tetraspanin 7 0.00745672
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0074507
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.00742201
RBBP4 retinoblastoma binding protein 4 0.0074166
SCD5 stearoyl-CoA desaturase 5 0.00740678
OXA1L oxidase (cytochrome c) assembly 1-like 0.00735244
CDC42SE1 CDC42 small effector 1 0.0073489
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.00734603
COL6A1 collagen, type VI, alpha 1 0.00730441
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.00729336
MAB21L2 mab-21-like 2 (C. elegans) 0.00727513
EMP1 epithelial membrane protein 1 0.00725675
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00724274
GRB7 growth factor receptor-bound protein 7 0.00723504
RAB25 RAB25, member RAS oncogene family 0.00718918
COL15A1 collagen, type XV, alpha 1 0.00715995
DAXX death-domain associated protein 0.00715654
FAM171A1 family with sequence similarity 171, member A1 0.0071562
PITX1 paired-like homeodomain 1 0.00713314
RIN2 Ras and Rab interactor 2 0.0071106
NFIB nuclear factor I/B 0.00711059
CRNN cornulin 0.00707923
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00706825
OPHN1 oligophrenin 1 0.00702287
MAOB monoamine oxidase B 0.00701457
PLPP3 phospholipid phosphatase 3 0.0070112
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.0069912
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00697536
TPPP3 tubulin polymerization-promoting protein family member 3 0.00695142
EHF ets homologous factor 0.00694796
WNT5A wingless-type MMTV integration site family, member 5A 0.00694395
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00693125
PMP22 peripheral myelin protein 22 0.00687425
CPE carboxypeptidase E 0.00687283
KRT13 keratin 13, type I 0.00685199
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00682988
ZNF652 zinc finger protein 652 0.00680494
RFX5 regulatory factor X, 5 (influences HLA class II expression) 0.00680387
KLK10 kallikrein-related peptidase 10 0.00679993
RNF167 ring finger protein 167 0.00679273
ANXA6 annexin A6 0.00678682
PDIA3 protein disulfide isomerase family A, member 3 0.00677239
AHNAK AHNAK nucleoprotein 0.00675158
MECOM MDS1 and EVI1 complex locus 0.0067439
FMOD fibromodulin 0.00673551
SRGN serglycin 0.00672004
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00671013
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00668394
RAI2 retinoic acid induced 2 0.00666928
GPM6B glycoprotein M6B 0.00666149
BACE1 beta-site APP-cleaving enzyme 1 0.00664722
DEFB1 defensin, beta 1 0.0066466
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00662178
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00658794
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00656981
PI3 peptidase inhibitor 3, skin-derived 0.00655647
RHCG Rh family, C glycoprotein 0.00654747
TPM2 tropomyosin 2 (beta) 0.00654629
OLFM1 olfactomedin 1 0.00654411
GUSBP3 glucuronidase, beta pseudogene 3 0.00647818
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00646685
CLU clusterin 0.00646405
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.00642382
CYBB cytochrome b-245, beta polypeptide 0.00640977
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.0064064
AREG amphiregulin 0.00640424
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00640404
ZFPM2 zinc finger protein, FOG family member 2 0.00638831
SYNM synemin, intermediate filament protein 0.00636971
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00636579
EPCAM epithelial cell adhesion molecule 0.0063287
RAB13 RAB13, member RAS oncogene family 0.00631879
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00630695
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00629642
CCP110 centriolar coiled coil protein 110kDa 0.00628075
CD9 CD9 molecule 0.00625986
CS citrate synthase 0.00625741
GPX1 glutathione peroxidase 1 0.00625669
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00625027
TMEM47 transmembrane protein 47 0.00623492
AGR2 anterior gradient 2 0.00621274
GSTM3 glutathione S-transferase mu 3 (brain) 0.00618269
SELE selectin E 0.0061712
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00615177
GSTK1 glutathione S-transferase kappa 1 0.00613827
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00613425
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00612312
SAP30 Sin3A-associated protein, 30kDa 0.00611793
EMP2 epithelial membrane protein 2 0.00609302
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00608159
EGR1 early growth response 1 0.00607915
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.0060553
GLUL glutamate-ammonia ligase 0.00604946
RNASET2 ribonuclease T2 0.00604878
TFRC transferrin receptor 0.0060386
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00602544
PGD phosphogluconate dehydrogenase 0.00601987
PDIA4 protein disulfide isomerase family A, member 4 0.00595089
PDE10A phosphodiesterase 10A 0.00594783
KRT19 keratin 19, type I 0.00594298
ISYNA1 inositol-3-phosphate synthase 1 0.00594087
PTCH1 patched 1 0.00590925
PEG3 paternally expressed 3 0.00589813
DLD dihydrolipoamide dehydrogenase 0.00589742
CD83 CD83 molecule 0.00589077
WSB1 WD repeat and SOCS box containing 1 0.0058553
PBX2P1 pre-B-cell leukemia homeobox 2 pseudogene 1 0.0058454
MFAP4 microfibrillar-associated protein 4 0.00583855
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.00583443
ZW10 zw10 kinetochore protein 0.00581519
CRABP1 cellular retinoic acid binding protein 1 0.00581087
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.00580713
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.00579882
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00579597
GLTP glycolipid transfer protein 0.00579385
PAX5 paired box 5 0.00577185
IFI27 interferon, alpha-inducible protein 27 0.00575325
STK39 serine threonine kinase 39 0.00573562
VWF von Willebrand factor 0.00569553
PSCA prostate stem cell antigen 0.00568136
KRT15 keratin 15, type I 0.00567546
OGN osteoglycin 0.00566786
FGFR2 fibroblast growth factor receptor 2 0.00565507
PPARG peroxisome proliferator-activated receptor gamma 0.00564556
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 0.00563672
PIP prolactin-induced protein 0.00562322
FBXO21 F-box protein 21 0.0056031
MPO myeloperoxidase 0.00560238
C6ORF48 chromosome 6 open reading frame 48 0.00558456
C3 complement component 3 0.00558411
ATAD2 ATPase family, AAA domain containing 2 0.00558252
PODXL podocalyxin-like 0.00557333
CENPE centromere protein E, 312kDa 0.00556835
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00556291
LIMCH1 LIM and calponin homology domains 1 0.00554767
CHPT1 choline phosphotransferase 1 0.0055464
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.00553524
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00552986
ATP5F1B ATP synthase F1 subunit beta 0.00552978
C14ORF132 chromosome 14 open reading frame 132 0.00550349
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00550097
PFKP phosphofructokinase, platelet 0.00549802
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00549532
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00547958
MNDA myeloid cell nuclear differentiation antigen 0.00546902
FKBP5 FK506 binding protein 5 0.00545905
DAZAP2 DAZ associated protein 2 0.00545661
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.00545057
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00544389
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.00544259
FOXF1 forkhead box F1 0.00544231
IRF8 interferon regulatory factor 8 0.00544133
ESYT1 extended synaptotagmin-like protein 1 0.00543727
MMP7 matrix metallopeptidase 7 0.00542791
FA2H fatty acid 2-hydroxylase 0.0054202
IK IK cytokine, down-regulator of HLA II 0.00540665
GREM1 gremlin 1, DAN family BMP antagonist 0.00540378
CNN3 calponin 3, acidic 0.00539844
KCTD12 potassium channel tetramerization domain containing 12 0.00539314
RGS4 regulator of G-protein signaling 4 0.00539237
CCL2 chemokine (C-C motif) ligand 2 0.00538005
NOTCH3 notch 3 0.00537718
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.00536051
MSMB microseminoprotein, beta- 0.00535738
CLEC11A C-type lectin domain family 11, member A 0.00533106
ESR1 estrogen receptor 1 0.00533076
NEBL nebulette 0.00532746
MDK midkine (neurite growth-promoting factor 2) 0.00531949
FRZB frizzled-related protein 0.00531663
TMPRSS11D transmembrane protease, serine 11D 0.00531074
MAGEA3 melanoma antigen family A3 0.00529941
SERINC5 serine incorporator 5 0.00528464

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -0.0155328
DAPK1 death-associated protein kinase 1 -0.0126288
GLS glutaminase -0.010062
TRIB3 tribbles pseudokinase 3 -0.00913331
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.0089025
IL32 interleukin 32 -0.00881847
ANKRD10 ankyrin repeat domain 10 -0.00873953
AKR1C2 aldo-keto reductase family 1, member C2 -0.00864402
CPVL carboxypeptidase, vitellogenic-like -0.00863197
LAPTM4B lysosomal protein transmembrane 4 beta -0.00861343
TDO2 tryptophan 2,3-dioxygenase -0.00848508
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00839097
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00830856
ADGRE1 adhesion G protein-coupled receptor E1 -0.00789696
PHACTR2 phosphatase and actin regulator 2 -0.00776849
CADM1 cell adhesion molecule 1 -0.00776149
STK10 serine/threonine kinase 10 -0.00761216
KLF10 Kruppel-like factor 10 -0.00760566
PIEZO2 piezo-type mechanosensitive ion channel component 2 -0.00760172
IL13RA2 interleukin 13 receptor, alpha 2 -0.00745941
NECTIN3 nectin cell adhesion molecule 3 -0.00745009
PLXNC1 plexin C1 -0.0073661
AKR1C1 aldo-keto reductase family 1, member C1 -0.00732392
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00731352
CALB1 calbindin 1, 28kDa -0.0072822
CD59 CD59 molecule, complement regulatory protein -0.00726084
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -0.0072231
LY96 lymphocyte antigen 96 -0.00721886
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00717611
AK4 adenylate kinase 4 -0.00710521
TENM1 teneurin transmembrane protein 1 -0.00709597
GSAP gamma-secretase activating protein -0.0070496
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00703429
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00703299
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00691851
PDGFC platelet derived growth factor C -0.00685437
ORC4 origin recognition complex, subunit 4 -0.00684936
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00681404
PDLIM7 PDZ and LIM domain 7 (enigma) -0.00678519
KIAA0125 KIAA0125 -0.00678229
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00661106
C1QB complement component 1, q subcomponent, B chain -0.00660413
CHN2 chimerin 2 -0.00659049
NKX2-1 NK2 homeobox 1 -0.00655086
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00645956
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00645353
CCN3 cellular communication network factor 3 -0.00642732
MSRB1 methionine sulfoxide reductase B1 -0.00640223
APOC2 apolipoprotein C-II -0.0063963
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00634779
FMO5 flavin containing monooxygenase 5 -0.0063454
RTN2 reticulon 2 -0.00633046
PON3 paraoxonase 3 -0.0062468
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.00624403
TLK2 tousled-like kinase 2 -0.00623867
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00620512
MICU2 mitochondrial calcium uptake 2 -0.0061745
PLS3 plastin 3 -0.00614398
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.00613738
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -0.00613125
CPB2 carboxypeptidase B2 (plasma) -0.00611972
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00608522
FABP1 fatty acid binding protein 1, liver -0.00607001
NDFIP1 Nedd4 family interacting protein 1 -0.00606741
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00605375
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00604393
HCLS1 hematopoietic cell-specific Lyn substrate 1 -0.00602683
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00598906
PGC progastricsin (pepsinogen C) -0.00593479
CEMIP cell migration inducing protein, hyaluronan binding -0.00592188
CD4 CD4 molecule -0.00592004
ALB albumin -0.00591267
PAWR PRKC, apoptosis, WT1, regulator -0.00584566
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -0.00584424
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00584307
RBPMS RNA binding protein with multiple splicing -0.00582065
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00581855
H1-2 H1.2 linker histone, cluster member -0.00579438
PTPRK protein tyrosine phosphatase, receptor type, K -0.00579429
CRYM crystallin, mu -0.00579371
AIM2 absent in melanoma 2 -0.0057844
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00578407
PNMA2 paraneoplastic Ma antigen 2 -0.00577832
SUN1 Sad1 and UNC84 domain containing 1 -0.00576743
CTH cystathionine gamma-lyase -0.00572192
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.00567596
APOC1 apolipoprotein C-I -0.00567542
COPS7A COP9 signalosome subunit 7A -0.00566005
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00564416
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00562867
FOSL1 FOS-like antigen 1 -0.00560557
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00557925
COG2 component of oligomeric golgi complex 2 -0.00557278
MFAP5 microfibrillar associated protein 5 -0.00557228
GPNMB glycoprotein (transmembrane) nmb -0.00556456
NOX4 NADPH oxidase 4 -0.00556273
MED13 mediator complex subunit 13 -0.00554334
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00552619
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00552396
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0055178
HIST1H2BK histone cluster 1, H2bk -0.00550647
SPEN spen family transcriptional repressor -0.00550477
CDCA4 cell division cycle associated 4 -0.00549968
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00544013
RGN regucalcin -0.00543622
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00542972
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -0.00542442
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00538218
C9 complement component 9 -0.00535954
CREB1 cAMP responsive element binding protein 1 -0.00534639
PTPRD protein tyrosine phosphatase, receptor type, D -0.0053388
TLN1 talin 1 -0.00533053
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00532253
MERTK MER proto-oncogene, tyrosine kinase -0.00530275
GSPT2 G1 to S phase transition 2 -0.00530069
PPIE peptidylprolyl isomerase E (cyclophilin E) -0.0052965
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00529541
STEAP3 STEAP family member 3, metalloreductase -0.00527071
SEPP1 selenoprotein P, plasma, 1 -0.00526282
BAG2 BCL2-associated athanogene 2 -0.00525381
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.005237
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.0052349
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00520498
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.00519871
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00518729
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00518503
RAB32 RAB32, member RAS oncogene family -0.00518413
RAD21 RAD21 homolog (S. pombe) -0.00516936
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00516556
C1QA complement component 1, q subcomponent, A chain -0.00516386
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00516306
ATP13A3 ATPase type 13A3 -0.00515706
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00512826
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00512447
PBX3 pre-B-cell leukemia homeobox 3 -0.00512047
TMEM126B transmembrane protein 126B -0.00509628
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 -0.00509475
ACE2 angiotensin I converting enzyme 2 -0.00508596
MCTP2 multiple C2 domains, transmembrane 2 -0.00508251
CCL20 chemokine (C-C motif) ligand 20 -0.00508117
TSPAN4 tetraspanin 4 -0.00508058
PAH phenylalanine hydroxylase -0.00507937
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00504951
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00504817
NUCB1 nucleobindin 1 -0.00504779
BCAS3 breast carcinoma amplified sequence 3 -0.00504088
HDGFL3 HDGF like 3 -0.00503674
DENND1B DENN/MADD domain containing 1B -0.00501497
NIBAN1 niban apoptosis regulator 1 -0.00500489
HOMER3 homer scaffolding protein 3 -0.00499254
RTL8C retrotransposon Gag like 8C -0.00499072
PTRH2 peptidyl-tRNA hydrolase 2 -0.00498144
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00497771
AGRN agrin -0.00496945
DHDDS dehydrodolichyl diphosphate synthase -0.00496313
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00494233
SF3A2 splicing factor 3a, subunit 2, 66kDa -0.00493442
CFHR4 complement factor H-related 4 -0.00493326
ANKRD49 ankyrin repeat domain 49 -0.00492353
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00491371
HNMT histamine N-methyltransferase -0.00491058
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -0.00490677
KRT20 keratin 20, type I -0.00490646
DPP4 dipeptidyl-peptidase 4 -0.00490268
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -0.00488584
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00488121
RGS20 regulator of G-protein signaling 20 -0.00487984
PCCB propionyl CoA carboxylase, beta polypeptide -0.00487979
ING3 inhibitor of growth family, member 3 -0.00487919
NR1H2 nuclear receptor subfamily 1, group H, member 2 -0.00487398
CBX3 chromobox homolog 3 -0.00485255
WBP5 WW domain binding protein 5 -0.00484298
PRKCZ protein kinase C, zeta -0.00483925
FST follistatin -0.0048306
ACTN1 actinin, alpha 1 -0.00482494
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00482438
NEFH neurofilament, heavy polypeptide -0.00480682
COMP cartilage oligomeric matrix protein -0.0047818
LEPROT leptin receptor overlapping transcript -0.00477211
AMACR alpha-methylacyl-CoA racemase -0.00475217
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00474663
NELL2 NEL-like 2 (chicken) -0.00473968
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -0.00473486
CLCA1 chloride channel accessory 1 -0.00472931
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -0.00472177
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -0.00470883
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00469553
ITGAV integrin, alpha V -0.00468961
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0046858
CDO1 cysteine dioxygenase type 1 -0.00468322
IFITM2 interferon induced transmembrane protein 2 -0.00467631
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00467483
NEK7 NIMA-related kinase 7 -0.00466121
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -0.00465633
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -0.00465392
ARMCX5 armadillo repeat containing, X-linked 5 -0.00464954
ZFAND5 zinc finger, AN1-type domain 5 -0.0046448
NCKAP1 NCK-associated protein 1 -0.00463008
IFITM1 interferon induced transmembrane protein 1 -0.00462748
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -0.00462323
LRRC59 leucine rich repeat containing 59 -0.00461986
GPX2 glutathione peroxidase 2 -0.00461782
ARL5A ADP-ribosylation factor-like 5A -0.00461273
PRMT3 protein arginine methyltransferase 3 -0.00461039
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -0.00459581
AKR1C3 aldo-keto reductase family 1, member C3 -0.00459499
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00459456
FZD5 frizzled class receptor 5 -0.0045901
TANK TRAF family member-associated NFKB activator -0.00457921
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.00457822
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00457773
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00455681
SMCO4 single-pass membrane protein with coiled-coil domains 4 -0.00455239
ACP6 acid phosphatase 6, lysophosphatidic -0.00454402
DIPK1A divergent protein kinase domain 1A -0.0045301
NAMPT nicotinamide phosphoribosyltransferase -0.00452853
UXS1 UDP-glucuronate decarboxylase 1 -0.0045275
DGUOK deoxyguanosine kinase -0.00452708
CDH18 cadherin 18, type 2 -0.00452141
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 -0.00452025
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -0.00450604
CD8A CD8a molecule -0.00449766
THOC7 THO complex 7 -0.00448874
PDE4A phosphodiesterase 4A, cAMP-specific -0.00447645
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -0.00446706
UFM1 ubiquitin-fold modifier 1 -0.00446155
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00445919
TMEM176B transmembrane protein 176B -0.00445788
SOCS2 suppressor of cytokine signaling 2 -0.00445182
MYL12B myosin, light chain 12B, regulatory -0.00445112
NT5DC2 5'-nucleotidase domain containing 2 -0.00444881
SLC38A4 solute carrier family 38, member 4 -0.00444835
IL6R interleukin 6 receptor -0.00444521
SCO2 SCO2 cytochrome c oxidase assembly protein -0.00444432
PSPH phosphoserine phosphatase -0.00443851
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 -0.00442806
SNX7 sorting nexin 7 -0.00442764
IL1A interleukin 1, alpha -0.00442733
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00442171
SIRT3 sirtuin 3 -0.00442161
CD48 CD48 molecule -0.00441762
ECHDC2 enoyl CoA hydratase domain containing 2 -0.00440544
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00440327
MSN moesin -0.00440022
FOXG1 forkhead box G1 -0.00439926
RFC2 replication factor C (activator 1) 2, 40kDa -0.00438991
OXTR oxytocin receptor -0.00437934
EIF3B eukaryotic translation initiation factor 3, subunit B -0.00437618
IPO5 importin 5 -0.00437148
AHI1 Abelson helper integration site 1 -0.00436572