STK11 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description serine/threonine kinase 11|This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6794)
External Link http://www.ncbi.nlm.nih.gov/gene/6794
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127 interacting proteins for STK11 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AHCYL1 adenosylhomocysteinase-like 1
AHCYL2 adenosylhomocysteinase-like 2
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP3M1 adaptor-related protein complex 3, mu 1 subunit
APP amyloid beta (A4) precursor protein
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ATM ATM serine/threonine kinase
BAG4 BCL2-associated athanogene 4
BCR breakpoint cluster region
BOP1 block of proliferation 1
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
C11ORF58 chromosome 11 open reading frame 58
CAB39 calcium binding protein 39
CAB39L calcium binding protein 39-like
CDC37 cell division cycle 37
CRTAP cartilage associated protein
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTNND1 catenin (cadherin-associated protein), delta 1
CUL4B cullin 4B
DKC1 dyskeratosis congenita 1, dyskerin
DMWD dystrophia myotonica, WD repeat containing
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3H eukaryotic translation initiation factor 3, subunit H
ETV4 ets variant 4
FAM122B family with sequence similarity 122B
FKBP5 FK506 binding protein 5
GPN1 GPN-loop GTPase 1
GPN3 GPN-loop GTPase 3
GSK3B glycogen synthase kinase 3 beta
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1B heat shock 70kDa protein 1B
IWS1 IWS1 homolog (S. cerevisiae)
KDM4A lysine (K)-specific demethylase 4A
KIF23 kinesin family member 23
LATS1 large tumor suppressor kinase 1
LIMS1 LIM and senescent cell antigen-like domains 1
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MELK maternal embryonic leucine zipper kinase
MLF1 myeloid leukemia factor 1
MLF2 myeloid leukemia factor 2
MOB4 MOB family member 4, phocein
MST1 macrophage stimulating 1
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NAF1 nuclear assembly factor 1 ribonucleoprotein
NELFE negative elongation factor complex member E
NHP2 NHP2 ribonucleoprotein
NOP10 NOP10 ribonucleoprotein
NUAK1 NUAK family, SNF1-like kinase, 1
NUAK2 NUAK family, SNF1-like kinase, 2
P3H1 prolyl 3-hydroxylase 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARD3 par-3 family cell polarity regulator
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRKCZ protein kinase C, zeta
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTEN phosphatase and tensin homolog
PTGES3 prostaglandin E synthase 3 (cytosolic)
RAD51AP1 RAD51 associated protein 1
RPAP3 RNA polymerase II associated protein 3
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCRIB scribbled planar cell polarity protein
SET SET nuclear proto-oncogene
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SIK1 salt-inducible kinase 1
SIK2 salt-inducible kinase 2
SIK3 SIK family kinase 3
SMAD4 SMAD family member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNRK SNF related kinase
STIP1 stress-induced phosphoprotein 1
STK11IP serine/threonine kinase 11 interacting protein
STRADA STE20-related kinase adaptor alpha
STRADB STE20-related kinase adaptor beta
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D23 TBC1 domain family, member 23
TCOF1 Treacher Collins-Franceschetti syndrome 1
TNIP2 TNFAIP3 interacting protein 2
TP53 tumor protein p53
TP63 tumor protein p63
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
UBC ubiquitin C
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
USP1 ubiquitin specific peptidase 1
USP11 ubiquitin specific peptidase 11
USP12 ubiquitin specific peptidase 12
WDR20 WD repeat domain 20
WDR48 WD repeat domain 48
WDR6 WD repeat domain 6
WDR70 WD repeat domain 70
WRN Werner syndrome, RecQ helicase-like
YLPM1 YLP motif containing 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB2 zinc finger and BTB domain containing 2
ZBTB33 zinc finger and BTB domain containing 33
ZNF639 zinc finger protein 639