STK11 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description serine/threonine kinase 11|This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6794)
External Link http://www.ncbi.nlm.nih.gov/gene/6794
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Genes

20 substrates of the kinase STK11 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MELK maternal embryonic leucine zipper kinase
NUAK1 NUAK family, SNF1-like kinase, 1
NUAK2 NUAK family, SNF1-like kinase, 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTEN phosphatase and tensin homolog
SIK1 salt-inducible kinase 1
SIK2 salt-inducible kinase 2
SIK3 SIK family kinase 3
SMAD4 SMAD family member 4
SNRK SNF related kinase
STK11 serine/threonine kinase 11
STRADA STE20-related kinase adaptor alpha
TP53 tumor protein p53