STK4 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description serine/threonine kinase 4|The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6789)
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11 substrates of the kinase STK4 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AURKB aurora kinase B
BECN1 beclin 1, autophagy related
FOXO3 forkhead box O3
H2AFX H2A histone family, member X
HIST1H2BB histone cluster 1, H2bb
MOB1B MOB kinase activator 1B
PRDX1 peroxiredoxin 1
STK38 serine/threonine kinase 38
STK4 serine/threonine kinase 4
TNNI3 troponin I type 3 (cardiac)