STT3A Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description STT3A, subunit of the oligosaccharyltransferase complex (catalytic)| (NCBI Entrez Gene Database, 3703)
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Genes

345 genes differentially expressed following the STT3A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 2.85154
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.85154
HCRTR1 hypocretin (orexin) receptor 1 2.85154
FABP1 fatty acid binding protein 1, liver 2.85154
TRIM17 tripartite motif containing 17 2.85154
MAGEA6 melanoma antigen family A6 2.85154
TSGA13 testis specific, 13 2.85154
HGD homogentisate 1,2-dioxygenase 2.85154
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.85154
SLC46A2 solute carrier family 46, member 2 2.85154
CTRC chymotrypsin C (caldecrin) 2.85154
SACK1A scaffolding CK1 anchoring protein A 2.85154
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.85154
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.85154
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.85154
HRH1 histamine receptor H1 2.85154
LURAP1L leucine rich adaptor protein 1-like 2.85154
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 2.85154
VTN vitronectin 2.85154
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 2.85154
MTTP microsomal triglyceride transfer protein 2.85154
CSTL1 cystatin-like 1 2.85154
CXCL2 chemokine (C-X-C motif) ligand 2 2.85154
CA9 carbonic anhydrase IX 2.85154
OR13C3 olfactory receptor, family 13, subfamily C, member 3 2.85154
RGPD3 RANBP2-like and GRIP domain containing 3 2.85154
TMEM200C transmembrane protein 200C 2.85154
MMP28 matrix metallopeptidase 28 2.85154
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 2.85154
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 2.85154
BIRC7 baculoviral IAP repeat containing 7 2.85154
ANKRD34A ankyrin repeat domain 34A 2.85154
LYNX1 Ly6/neurotoxin 1 2.85154
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 2.85154
XCL1 chemokine (C motif) ligand 1 2.85154
XCL2 chemokine (C motif) ligand 2 2.85154
RSPO3 R-spondin 3 2.85154
MFAP4 microfibrillar-associated protein 4 2.85154
C19ORF67 chromosome 19 open reading frame 67 2.85154
SHCBP1L SHC SH2-domain binding protein 1-like 2.85154
SPINT3 serine peptidase inhibitor, Kunitz type, 3 2.85154
BMP3 bone morphogenetic protein 3 2.85154
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2.85154
REELD1 reeler domain containing 1 2.85154
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.85154
C1QTNF9B C1q and tumor necrosis factor related protein 9B 2.85154
TMPRSS7 transmembrane protease, serine 7 2.85154
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.85154
IMPG1 interphotoreceptor matrix proteoglycan 1 2.85154
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 2.85154
KL klotho 2.85154
WNT9B wingless-type MMTV integration site family, member 9B 2.85154
KRT80 keratin 80, type II 2.85154
FRG2C FSHD region gene 2 family, member C 2.85154
OR2T8 olfactory receptor, family 2, subfamily T, member 8 2.85154
DUSP13B dual specificity phosphatase 13B 2.85154
ALKAL1 ALK and LTK ligand 1 2.85154
PABIR2 PABIR family member 2 2.85154
PLG plasminogen 2.85154
ZAR1 zygote arrest 1 2.85154
MCHR2 melanin-concentrating hormone receptor 2 2.85154
GRAMD1B GRAM domain containing 1B 2.85154
DNAAF1 dynein, axonemal, assembly factor 1 2.85154
LRRC72 leucine rich repeat containing 72 2.85154
FAM131C family with sequence similarity 131, member C 2.85154
CATSPER3 cation channel, sperm associated 3 2.85154
OR51B5 olfactory receptor, family 51, subfamily B, member 5 2.85154
FPGT fucose-1-phosphate guanylyltransferase 2.85154
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.85154
DAO D-amino-acid oxidase 2.85154
WNT11 wingless-type MMTV integration site family, member 11 2.85154
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 2.85154
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 2.85154
MSX1 msh homeobox 1 2.85154
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 2.85154
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.85154
PGA5 pepsinogen 5, group I (pepsinogen A) 2.85154
PLB1 phospholipase B1 2.85154
UTS2 urotensin 2 2.85154
PGLYRP2 peptidoglycan recognition protein 2 2.85154
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.85154
TCF23 transcription factor 23 2.85154
NPFF neuropeptide FF-amide peptide precursor 2.85154
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 2.85154
CLDN9 claudin 9 2.85154
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.85154
TEX26 testis expressed 26 2.85154
CLEC4G C-type lectin domain family 4, member G 2.85154
AKNAD1 AKNA domain containing 1 2.85154
ADAM7 ADAM metallopeptidase domain 7 2.85154
GOLGA6C golgin A6 family, member C 2.85154
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.85154
GLOD5 glyoxalase domain containing 5 2.85154
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.85154
BTNL9 butyrophilin-like 9 2.85154
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.85154
SUPT20HL1 suppressor of Ty 20 homolog (S. cerevisiae)-like 1 2.85154
CCL27 chemokine (C-C motif) ligand 27 2.85154
CTF1 cardiotrophin 1 2.85154
APOB apolipoprotein B 2.85154
BLID BH3-like motif containing, cell death inducer 2.85154
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 2.85154
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.85154
C9ORF57 chromosome 9 open reading frame 57 2.85154
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2.85154
SFRP5 secreted frizzled-related protein 5 2.85154
C22ORF31 chromosome 22 open reading frame 31 2.85154
TTC29 tetratricopeptide repeat domain 29 2.85154
PLA2G5 phospholipase A2, group V 2.85154
ETV3L ets variant 3-like 2.85154
GBX2 gastrulation brain homeobox 2 2.85154
LAMB4 laminin, beta 4 2.85154
ESPNL espin-like 2.85154
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.85154
C1ORF105 chromosome 1 open reading frame 105 2.85154
LHX5 LIM homeobox 5 2.85154
KLHDC8A kelch domain containing 8A 2.85154
TPPP2 tubulin polymerization-promoting protein family member 2 2.85154
GOLGA8M golgin A8 family, member M 2.85154
ARL13A ADP-ribosylation factor-like 13A 2.85154
FGR FGR proto-oncogene, Src family tyrosine kinase 2.85154
CALR3 calreticulin 3 2.85154
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.85154
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.85154
ADGRF5 adhesion G protein-coupled receptor F5 2.85154
R3HDML R3H domain containing-like 2.85154
ADAM29 ADAM metallopeptidase domain 29 2.85154
LEP leptin 2.85154
TMPRSS13 transmembrane protease, serine 13 2.85154
WFDC13 WAP four-disulfide core domain 13 2.85154
NFE2 nuclear factor, erythroid 2 2.85154
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.85154
KIF19 kinesin family member 19 2.85154
FRMPD1 FERM and PDZ domain containing 1 2.85154
TGM6 transglutaminase 6 2.85154
SERTM1 serine-rich and transmembrane domain containing 1 2.85154
TMEM215 transmembrane protein 215 2.85154
C17ORF78 chromosome 17 open reading frame 78 2.85154
ASGR2 asialoglycoprotein receptor 2 2.85154
RXRG retinoid X receptor, gamma 2.85154
NPAS4 neuronal PAS domain protein 4 2.85154
RAB7B RAB7B, member RAS oncogene family 2.85154
C10ORF90 chromosome 10 open reading frame 90 2.85154
OR52I2 olfactory receptor, family 52, subfamily I, member 2 2.85154
ZNF804B zinc finger protein 804B 2.85154
PI16 peptidase inhibitor 16 2.85154
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 2.85154
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2 2.84043
TMEM17 transmembrane protein 17 2.75143
HYI hydroxypyruvate isomerase (putative) 2.75143
RGS7 regulator of G-protein signaling 7 2.73082
RASAL2 RAS protein activator like 2 2.55944
NPSR1 neuropeptide S receptor 1 2.55306
KASH5 KASH domain containing 5 2.53486
EPHA3 EPH receptor A3 2.53486
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.53486
PDIA6 protein disulfide isomerase family A, member 6 2.52587
IDO1 indoleamine 2,3-dioxygenase 1 2.50281
MANF mesencephalic astrocyte-derived neurotrophic factor 2.47898
CCDC91 coiled-coil domain containing 91 2.47898
PODXL2 podocalyxin-like 2 2.4428
ZNF83 zinc finger protein 83 2.42046
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.39291
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 2.39165
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.38433
TADA1 transcriptional adaptor 1 2.37594
GLCCI1 glucocorticoid induced 1 2.34561
SLITRK1 SLIT and NTRK-like family, member 1 2.33093
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) 2.31146
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 2.31146
HEATR5B HEAT repeat containing 5B 2.31062
ASCC1 activating signal cointegrator 1 complex subunit 1 2.30355
EXOC4 exocyst complex component 4 2.29706
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 2.29692
LRRC4C leucine rich repeat containing 4C 2.28516
UBA6 ubiquitin-like modifier activating enzyme 6 2.27967
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 2.27172
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 2.26245
HDX highly divergent homeobox 2.25268
CDH4 cadherin 4, type 1, R-cadherin (retinal) 2.24396
PHF12 PHD finger protein 12 2.23618
RPGR retinitis pigmentosa GTPase regulator 2.21924
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2.21078
RCOR2 REST corepressor 2 2.20207
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.17962
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 2.15899
PNISR PNN-interacting serine/arginine-rich protein 2.14572
ZNF300 zinc finger protein 300 2.14123
PPIB peptidylprolyl isomerase B (cyclophilin B) 2.13209
TXNL4B thioredoxin-like 4B 2.13048
BNC2 basonuclin 2 2.1275
ADSS2 adenylosuccinate synthase 2 2.12211
MRPL53 mitochondrial ribosomal protein L53 2.09063
SMDT1 single-pass membrane protein with aspartate-rich tail 1 2.08228
RPL12 ribosomal protein L12 2.07714
RAB3B RAB3B, member RAS oncogene family 2.07687
ARNT aryl hydrocarbon receptor nuclear translocator 2.07652
ATOX1 antioxidant 1 copper chaperone 2.06561
SLC12A8 solute carrier family 12, member 8 2.04828
MARCHF5 membrane associated ring-CH-type finger 5 2.04603
S1PR5 sphingosine-1-phosphate receptor 5 2.04603
SMC6 structural maintenance of chromosomes 6 2.04469
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 2.02111
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 2.00461
BLM Bloom syndrome, RecQ helicase-like 2.00432
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 2.00041

decreased expression

Symbol Name Standardized Value
FAM216B family with sequence similarity 216, member B -2.85154
IFITM10 interferon induced transmembrane protein 10 -2.85154
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 -2.85154
FAM110D family with sequence similarity 110, member D -2.85154
ACAN aggrecan -2.85154
THEM6 thioesterase superfamily member 6 -2.85154
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 -2.85154
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 -2.85154
PRICKLE3 prickle homolog 3 (Drosophila) -2.85154
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -2.85154
PTGDR prostaglandin D2 receptor (DP) -2.85154
MAPRE3 microtubule-associated protein, RP/EB family, member 3 -2.85154
ZNF284 zinc finger protein 284 -2.85154
SMIM45 small integral membrane protein 45 -2.85154
SBK2 SH3 domain binding kinase family, member 2 -2.85154
ZNF597 zinc finger protein 597 -2.85154
ENOSF1 enolase superfamily member 1 -2.85154
CCDC61 coiled-coil domain containing 61 -2.85154
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) -2.85154
ATG4A autophagy related 4A, cysteine peptidase -2.85154
OVCH1 ovochymase 1 -2.85154
PTK6 protein tyrosine kinase 6 -2.85154
IKZF3 IKAROS family zinc finger 3 (Aiolos) -2.85154
LCN12 lipocalin 12 -2.85154
FAM181B family with sequence similarity 181, member B -2.85154
LVRN laeverin -2.85154
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.85154
FAM161B family with sequence similarity 161, member B -2.85154
MFSD6 major facilitator superfamily domain containing 6 -2.85154
KIAA0319 KIAA0319 -2.85154
KAT2B K(lysine) acetyltransferase 2B -2.85154
GLB1L galactosidase, beta 1-like -2.85154
ZNF396 zinc finger protein 396 -2.85154
SERF1A small EDRK-rich factor 1A (telomeric) -2.85154
PTH2 parathyroid hormone 2 -2.85154
C1ORF162 chromosome 1 open reading frame 162 -2.85154
ZNF365 zinc finger protein 365 -2.85154
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -2.85154
FASTKD5 FAST kinase domains 5 -2.85154
CCKBR cholecystokinin B receptor -2.85154
ITGA10 integrin, alpha 10 -2.85154
SPEF2 sperm flagellar 2 -2.85154
SMIM10 small integral membrane protein 10 -2.85154
MYO15A myosin XVA -2.85154
SCN1B sodium channel, voltage gated, type I beta subunit -2.85154
GBA1 glucosylceramidase beta 1 -2.85154
IQCN IQ motif containing N -2.85154
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) -2.85154
RHEX regulator of hemoglobinization and erythroid cell expansion -2.85154
CDADC1 cytidine and dCMP deaminase domain containing 1 -2.85154
CCDC78 coiled-coil domain containing 78 -2.85154
GDPGP1 GDP-D-glucose phosphorylase 1 -2.85154
LRRC19 leucine rich repeat containing 19 -2.85154
KLK7 kallikrein-related peptidase 7 -2.85154
FOS FBJ murine osteosarcoma viral oncogene homolog -2.85154
GJD3 gap junction protein, delta 3, 31.9kDa -2.85154
BATF3 basic leucine zipper transcription factor, ATF-like 3 -2.85154
GPX2 glutathione peroxidase 2 -2.85154
ADGRA2 adhesion G protein-coupled receptor A2 -2.85154
RADIL Ras association and DIL domains -2.85154
GBP4 guanylate binding protein 4 -2.85154
CXCR4 chemokine (C-X-C motif) receptor 4 -2.85154
CPHXL2 cytoplasmic polyadenylated homeobox like 2 -2.85154
NANP N-acetylneuraminic acid phosphatase -2.85154
OXA1L oxidase (cytochrome c) assembly 1-like -2.85154
RABIF RAB interacting factor -2.85154
MUC19 mucin 19, oligomeric -2.85154
CFAP119 cilia and flagella associated protein 119 -2.85154
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -2.73892
EI24 etoposide induced 2.4 -2.72799
FOXL2NB FOXL2 neighbor -2.66452
AOC2 amine oxidase, copper containing 2 (retina-specific) -2.66452
HPSE heparanase -2.6542
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.61648
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 -2.61223
PPIF peptidylprolyl isomerase F -2.53486
UBTD2 ubiquitin domain containing 2 -2.50843
JMJD8 jumonji domain containing 8 -2.49497
ZPR1 ZPR1 zinc finger -2.47898
ZNF501 zinc finger protein 501 -2.43541
SPOPL speckle-type POZ protein-like -2.41152
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -2.40561
LRP2 low density lipoprotein receptor-related protein 2 -2.39184
TMEM125 transmembrane protein 125 -2.39165
RBBP4 retinoblastoma binding protein 4 -2.38054
ANKIB1 ankyrin repeat and IBR domain containing 1 -2.36604
PDGFRB platelet-derived growth factor receptor, beta polypeptide -2.3562
ASB6 ankyrin repeat and SOCS box containing 6 -2.3562
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.33886
MCM5 minichromosome maintenance complex component 5 -2.33792
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -2.32863
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -2.31146
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3 -2.30355
ECT2 epithelial cell transforming 2 -2.26498
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit -2.23568
LAGE3 L antigen family, member 3 -2.2244
ALG3 ALG3, alpha-1,3- mannosyltransferase -2.2065
LMBR1L limb development membrane protein 1-like -2.20368
QPCT glutaminyl-peptide cyclotransferase -2.20207
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 -2.19055
MCFD2 multiple coagulation factor deficiency 2 -2.1896
SP2 Sp2 transcription factor -2.18479
TUBB tubulin, beta class I -2.18433
FBXO30 F-box protein 30 -2.18258
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -2.17582
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 -2.16414
SOX6 SRY (sex determining region Y)-box 6 -2.16414
ADCY6 adenylate cyclase 6 -2.1636
SRPX sushi-repeat containing protein, X-linked -2.1636
TMEM74 transmembrane protein 74 -2.1636
ZNF747 zinc finger protein 747 -2.16356
GARNL3 GTPase activating Rap/RanGAP domain-like 3 -2.16356
RND1 Rho family GTPase 1 -2.15899
NINJ2 ninjurin 2 -2.15899
PRKG2 protein kinase, cGMP-dependent, type II -2.15375
CDK3 cyclin-dependent kinase 3 -2.15375
LRRC41 leucine rich repeat containing 41 -2.14943
SART3 squamous cell carcinoma antigen recognized by T cells 3 -2.14123
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -2.13048
OTUD4 OTU deubiquitinase 4 -2.11989
ZXDC ZXD family zinc finger C -2.11135
FNBP4 formin binding protein 4 -2.11135
U2AF1 U2 small nuclear RNA auxiliary factor 1 -2.10383
BAX BCL2-associated X protein -2.09852
MRPS25 mitochondrial ribosomal protein S25 -2.09444
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 -2.09074
KIF9 kinesin family member 9 -2.08013
MINK1 misshapen-like kinase 1 -2.07714
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -2.07249
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.0665
FAM227A family with sequence similarity 227, member A -2.06007
POLR1C polymerase (RNA) I polypeptide C, 30kDa -2.05368
NXPH1 neurexophilin 1 -2.04828
AGMAT agmatine ureohydrolase (agmatinase) -2.04828
TMEM35B transmembrane protein 35B -2.02685
A2ML1 alpha-2-macroglobulin-like 1 -2.02685
KLHL8 kelch-like family member 8 -2.00727
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -2.00432
SPP1 secreted phosphoprotein 1 -2.00048