STT3B Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description STT3B, subunit of the oligosaccharyltransferase complex (catalytic)|The protein encoded by this gene is a catalytic subunit of a protein complex that transfers oligosaccharides onto asparagine residues. Defects in this gene are a cause of congenital disorder of glycosylation Ix (CDG1X). [provided by RefSeq, Jun 2014] (NCBI Entrez Gene Database, 201595)
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Genes

311 genes differentially expressed following the STT3B gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PLGLB1 plasminogen-like B1 2.77509
VNN1 vanin 1 2.77509
SMIM5 small integral membrane protein 5 2.77509
TREH trehalase (brush-border membrane glycoprotein) 2.77509
LY6K lymphocyte antigen 6 complex, locus K 2.77509
BTNL8 butyrophilin-like 8 2.77509
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 2.77509
PCDHB10 protocadherin beta 10 2.77509
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 2.77509
TGM6 transglutaminase 6 2.77509
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.77509
TTLL9 tubulin tyrosine ligase-like family member 9 2.77509
PRR20G proline rich 20G 2.77509
CFP complement factor properdin 2.77509
UROC1 urocanate hydratase 1 2.77509
KLHL1 kelch-like family member 1 2.77509
KLHL6 kelch-like family member 6 2.77509
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.77509
RNF222 ring finger protein 222 2.77509
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.77509
CAPNS2 calpain, small subunit 2 2.76733
GSX2 GS homeobox 2 2.76733
NCF1 neutrophil cytosolic factor 1 2.76733
C1ORF116 chromosome 1 open reading frame 116 2.76733
TRIM15 tripartite motif containing 15 2.76733
KNG1 kininogen 1 2.76733
PROKR1 prokineticin receptor 1 2.76733
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2.76733
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.76733
UCN urocortin 2.76733
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.76733
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 2.76733
SLC25A41 solute carrier family 25, member 41 2.76733
PSCA prostate stem cell antigen 2.76733
CRX cone-rod homeobox 2.76733
CLEC5A C-type lectin domain family 5, member A 2.76733
DPPA4 developmental pluripotency associated 4 2.76733
HBB hemoglobin, beta 2.76733
PRDM13 PR domain containing 13 2.76733
HMX3 H6 family homeobox 3 2.76733
FGF6 fibroblast growth factor 6 2.76733
SPATA31G1 SPATA31 subfamily G member 1 2.76733
RGPD3 RANBP2-like and GRIP domain containing 3 2.76733
RGPD4 RANBP2-like and GRIP domain containing 4 2.76733
SKOR1 SKI family transcriptional corepressor 1 2.76733
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.76733
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 2.76733
PBOV1 prostate and breast cancer overexpressed 1 2.76733
SFTPB surfactant protein B 2.76733
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.76733
TDRD1 tudor domain containing 1 2.76733
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 2.76733
TUBB8 tubulin, beta 8 class VIII 2.76733
SPMIP11 sperm microtubule inner protein 11 2.76733
SRGN serglycin 2.76733
TEDDM1 transmembrane epididymal protein 1 2.76733
WDR64 WD repeat domain 64 2.76733
CSAG2 CSAG family, member 2 2.76733
ACE2 angiotensin I converting enzyme 2 2.76733
MOV10L1 Mov10 RISC complex RNA helicase like 1 2.76733
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 2.76733
TAS1R1 taste receptor, type 1, member 1 2.76733
HTRA4 HtrA serine peptidase 4 2.76733
GPR35 G protein-coupled receptor 35 2.76733
CCER1 coiled-coil glutamate-rich protein 1 2.76733
EZHIP EZH inhibitory protein 2.76733
DNAAF6 dynein axonemal assembly factor 6 2.76733
CIROP ciliated left-right organizer metallopeptidase 2.76733
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 2.76733
HTD2 hydroxyacyl-thioester dehydratase type 2 2.76733
DERPC DERPC proline and glycine rich nuclear protein 2.76733
PHF24 PHD finger protein 24 2.76733
HAO2 hydroxyacid oxidase 2 (long chain) 2.76733
VCX3A variable charge, X-linked 3A 2.76733
PTCHD1 patched domain containing 1 2.76733
UTS2 urotensin 2 2.76733
FAM170A family with sequence similarity 170, member A 2.76733
ATP13A5 ATPase type 13A5 2.76733
TBX21 T-box 21 2.76733
SLC22A15 solute carrier family 22, member 15 2.76733
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 2.76733
SIX1 SIX homeobox 1 2.76733
TMPRSS11A transmembrane protease, serine 11A 2.76733
LAPTM5 lysosomal protein transmembrane 5 2.76733
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.76733
CHRD chordin 2.76733
IDO2 indoleamine 2,3-dioxygenase 2 2.76733
CELA2A chymotrypsin-like elastase family, member 2A 2.76733
GSC goosecoid homeobox 2.76733
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 2.76733
LSP1 lymphocyte-specific protein 1 2.76733
OR2L2 olfactory receptor, family 2, subfamily L, member 2 2.76733
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 2.76733
TLR4 toll-like receptor 4 2.76733
NR1I3 nuclear receptor subfamily 1, group I, member 3 2.76733
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 2.76733
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.76733
VWA3B von Willebrand factor A domain containing 3B 2.76733
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.76733
IL36R interleukin 36 receptor 2.76733
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.76733
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 2.76733
FAM177B family with sequence similarity 177, member B 2.76733
PRM1 protamine 1 2.76733
KLF1 Kruppel-like factor 1 (erythroid) 2.76733
HIGD2B HIG1 hypoxia inducible domain family, member 2B 2.76733
SCML4 sex comb on midleg-like 4 (Drosophila) 2.76733
BTNL3 butyrophilin-like 3 2.76733
EDN1 endothelin 1 2.76733
PLSCR5 phospholipid scramblase family, member 5 2.76733
KRTAP5-10 keratin associated protein 5-10 2.76733
TTC9B tetratricopeptide repeat domain 9B 2.76733
PYHIN1 pyrin and HIN domain family, member 1 2.76733
SMIM22 small integral membrane protein 22 2.76733
VWA7 von Willebrand factor A domain containing 7 2.76733
ISL2 ISL LIM homeobox 2 2.76733
NLRP14 NLR family, pyrin domain containing 14 2.76733
GOLGA8O golgin A8 family, member O 2.76733
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 2.76733
ERVV-1 endogenous retrovirus group V, member 1 2.76733
LRRC25 leucine rich repeat containing 25 2.76733
PGR progesterone receptor 2.76733
CA5A carbonic anhydrase VA, mitochondrial 2.76733
PENK proenkephalin 2.76733
ITGB7 integrin, beta 7 2.76733
IL9R interleukin 9 receptor 2.76733
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.76733
TBX1 T-box 1 2.76733
PRPH peripherin 2.76733
CDRT15L2 CMT1A duplicated region transcript 15-like 2 2.76733
KLK12 kallikrein-related peptidase 12 2.76733
KLK15 kallikrein-related peptidase 15 2.76733
SHOX2 short stature homeobox 2 2.76733
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.76733
TEX38 testis expressed 38 2.76733
MEIG1 meiosis/spermiogenesis associated 1 2.76733
NR2F1 nuclear receptor subfamily 2, group F, member 1 2.76733
TICAM1 toll-like receptor adaptor molecule 1 2.76733
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 2.76733
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.76733
C5ORF46 chromosome 5 open reading frame 46 2.76733
ASCL1 achaete-scute family bHLH transcription factor 1 2.76733
TGM3 transglutaminase 3 2.76733
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.76733
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 2.76733
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.76733
BACE1 beta-site APP-cleaving enzyme 1 2.76733
PRAP1 proline-rich acidic protein 1 2.76733
CDC14C cell division cycle 14C 2.76733
GRAP2 GRB2-related adaptor protein 2 2.76733
IL33 interleukin 33 2.76733
USH1C Usher syndrome 1C (autosomal recessive, severe) 2.70721
GADL1 glutamate decarboxylase-like 1 2.69382
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.69382
FBXL22 F-box and leucine-rich repeat protein 22 2.69382
NLE1 notchless homolog 1 (Drosophila) 2.67227
FMN1 formin 1 2.67104
SNRK SNF related kinase 2.67104
MYRFL myelin regulatory factor-like 2.65342
AMZ1 archaelysin family metallopeptidase 1 2.64823
PCBP1 poly(rC) binding protein 1 2.64823
FAM50A family with sequence similarity 50, member A 2.64823
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.64823
C5ORF58 chromosome 5 open reading frame 58 2.6162
WASHC1 WASH complex subunit 1 2.60881
SF3B1 splicing factor 3b, subunit 1, 155kDa 2.60243
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 2.55785
SMAD2 SMAD family member 2 2.54118
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.52506
VIPR2 vasoactive intestinal peptide receptor 2 2.46131
HP1BP3 heterochromatin protein 1, binding protein 3 2.45915
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 2.45333
CALHM2 calcium homeostasis modulator 2 2.45183
RAB2B RAB2B, member RAS oncogene family 2.4516
NRP1 neuropilin 1 2.40006
IRF2BP2 interferon regulatory factor 2 binding protein 2 2.39659
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 2.37596
VMA12 vacuolar ATPase assembly factor VMA12 2.3576
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.35534
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2.34462
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2.28689
PLIN1 perilipin 1 2.27593
ELMO2 engulfment and cell motility 2 2.26746
KIF1A kinesin family member 1A 2.25651
WDR24 WD repeat domain 24 2.23796
TMEM63C transmembrane protein 63C 2.21918
FSIP1 fibrous sheath interacting protein 1 2.21745
SBF2 SET binding factor 2 2.1986
PRMT2IP PRMT2 interacting protein 2.18918
GTF2I general transcription factor IIi 2.18918
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) 2.17479
ASCC2 activating signal cointegrator 1 complex subunit 2 2.17181
CALHM6 calcium homeostasis modulator family member 6 2.16925
MCTP2 multiple C2 domains, transmembrane 2 2.16581
FHL3 four and a half LIM domains 3 2.1571
CLTC clathrin, heavy chain (Hc) 2.15341
PLAUR plasminogen activator, urokinase receptor 2.14642
REDIC1 regulator of DNA class I crossover intermediates 1 2.13278
C3ORF62 chromosome 3 open reading frame 62 2.12196
ANO6 anoctamin 6 2.12196
RGS10 regulator of G-protein signaling 10 2.12163
NEK7 NIMA-related kinase 7 2.11522
RING1 ring finger protein 1 2.11522
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1 2.1138
ZNF644 zinc finger protein 644 2.09485
ZNF420 zinc finger protein 420 2.09405
ATP9A ATPase, class II, type 9A 2.08464
NTN1 netrin 1 2.07751
SCP2 sterol carrier protein 2 2.07602
HAUS5 HAUS augmin-like complex, subunit 5 2.07426
TMED5 transmembrane emp24 protein transport domain containing 5 2.06589
CDC40 cell division cycle 40 2.0642
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.05369
GLIPR2 GLI pathogenesis-related 2 2.05369
RSF1 remodeling and spacing factor 1 2.05369
C1ORF35 chromosome 1 open reading frame 35 2.05229
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 2.05229
FBXO34 F-box protein 34 2.04777
MBD5 methyl-CpG binding domain protein 5 2.0399
TSPAN6 tetraspanin 6 2.01403
ANO1 anoctamin 1, calcium activated chloride channel 2.00934

decreased expression

Symbol Name Standardized Value
NRIP2 nuclear receptor interacting protein 2 -2.77509
PTPRO protein tyrosine phosphatase, receptor type, O -2.77509
NCLN nicalin -2.76733
SDK1 sidekick cell adhesion molecule 1 -2.76733
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) -2.76733
CYSRT1 cysteine-rich tail protein 1 -2.76733
PRSS22 protease, serine, 22 -2.76733
INHBA inhibin, beta A -2.76733
LMNTD2 lamin tail domain containing 2 -2.76733
H2AZ2 H2A.Z variant histone 2 -2.76733
STKLD1 serine/threonine kinase-like domain containing 1 -2.76733
ANKDD1B ankyrin repeat and death domain containing 1B -2.76733
SLC25A35 solute carrier family 25, member 35 -2.76733
TAS2R30 taste receptor, type 2, member 30 -2.76733
GGT1 gamma-glutamyltransferase 1 -2.76733
LIPT2-AS1 LIPT2 antisense RNA 1 -2.76733
CASR calcium-sensing receptor -2.75003
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 -2.68548
CHD6 chromodomain helicase DNA binding protein 6 -2.67025
ITLN2 intelectin 2 -2.64823
F5 coagulation factor V (proaccelerin, labile factor) -2.64823
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) -2.64823
LOC105378220 macrophage receptor MARCO-like -2.64823
GPR75 G protein-coupled receptor 75 -2.64823
MFAP4 microfibrillar-associated protein 4 -2.64823
OXTR oxytocin receptor -2.64823
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 -2.64823
TMEM132D transmembrane protein 132D -2.64823
IMPG2 interphotoreceptor matrix proteoglycan 2 -2.64823
CTXND1 cortexin domain containing 1 -2.64823
SFRP5 secreted frizzled-related protein 5 -2.64823
FAM186B family with sequence similarity 186, member B -2.64823
WNT4 wingless-type MMTV integration site family, member 4 -2.64823
HPR haptoglobin-related protein -2.64823
TDRD10 tudor domain containing 10 -2.64823
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 -2.64823
LOC124903233 uncharacterized LOC124903233 -2.64823
DQX1 DEAQ box RNA-dependent ATPase 1 -2.64823
MRAP melanocortin 2 receptor accessory protein -2.64823
ROM1 retinal outer segment membrane protein 1 -2.64823
GHRL ghrelin/obestatin prepropeptide -2.61629
RAP2B RAP2B, member of RAS oncogene family -2.57825
CERS2 ceramide synthase 2 -2.57073
CFAP77 cilia and flagella associated protein 77 -2.55176
MICALL2 MICAL-like 2 -2.54272
SIGLEC10 sialic acid binding Ig-like lectin 10 -2.54272
KBTBD12 kelch repeat and BTB (POZ) domain containing 12 -2.52557
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -2.51501
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.46131
GADD45B growth arrest and DNA-damage-inducible, beta -2.45333
MLXIP MLX interacting protein -2.44157
CAMTA1 calmodulin binding transcription activator 1 -2.37596
TRIM22 tripartite motif containing 22 -2.33297
OMD osteomodulin -2.26746
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -2.26427
LGALSL lectin, galactoside-binding-like -2.25651
TMEM213 transmembrane protein 213 -2.25149
MYO1B myosin IB -2.23796
CHIC1 cysteine-rich hydrophobic domain 1 -2.21918
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -2.21918
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -2.21099
FIGNL1 fidgetin-like 1 -2.17479
RRAGA Ras-related GTP binding A -2.16925
RASD2 RASD family, member 2 -2.16925
TSNAXIP1 translin-associated factor X interacting protein 1 -2.16925
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.16767
FZD2 frizzled class receptor 2 -2.16051
MATN1 matrilin 1, cartilage matrix protein -2.15819
ZDHHC21 zinc finger, DHHC-type containing 21 -2.14642
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -2.12769
HDX highly divergent homeobox -2.11522
DOLK dolichol kinase -2.11522
KIFC1 kinesin family member C1 -2.11522
CALB1 calbindin 1, 28kDa -2.11446
TYW5 tRNA-yW synthesizing protein 5 -2.10564
C19ORF53 chromosome 19 open reading frame 53 -2.09405
RNF144A ring finger protein 144A -2.09088
VRK1 vaccinia related kinase 1 -2.0855
GORAB golgin, RAB6-interacting -2.07751
CDH26 cadherin 26 -2.07599
TNPO1 transportin 1 -2.07001
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 -2.06992
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -2.0642
GAL3ST1 galactose-3-O-sulfotransferase 1 -2.05717
PNMA3 paraneoplastic Ma antigen 3 -2.05717
NHLRC2 NHL repeat containing 2 -2.04777
ZRANB2 zinc finger, RAN-binding domain containing 2 -2.04076
NR4A1 nuclear receptor subfamily 4, group A, member 1 -2.0399
UGDH UDP-glucose 6-dehydrogenase -2.0399
CCDC7 coiled-coil domain containing 7 -2.03921