STX4 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description syntaxin 4| (NCBI Entrez Gene Database, 6810)
Similar Terms
Downloads & Tools

Genes

356 genes differentially expressed following the STX4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.58748
CABS1 calcium-binding protein, spermatid-specific 1 2.58748
PAX3 paired box 3 2.58748
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.58748
NPSR1 neuropeptide S receptor 1 2.58748
CEP295NL CEP295 N-terminal like 2.58748
LRG1 leucine-rich alpha-2-glycoprotein 1 2.58748
GYPB glycophorin B (MNS blood group) 2.58748
C19ORF67 chromosome 19 open reading frame 67 2.58748
SUSD2 sushi domain containing 2 2.58748
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.58748
MED7 mediator complex subunit 7 2.58748
CLEC19A C-type lectin domain family 19, member A 2.58748
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.58748
COLEC10 collectin sub-family member 10 (C-type lectin) 2.58748
SLC26A7 solute carrier family 26 (anion exchanger), member 7 2.58748
SLC26A3 solute carrier family 26 (anion exchanger), member 3 2.58748
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.58748
XAF1 XIAP associated factor 1 2.58748
CELF6 CUGBP, Elav-like family member 6 2.58748
NANOS3 nanos homolog 3 (Drosophila) 2.58748
HCRTR1 hypocretin (orexin) receptor 1 2.58748
RAB17 RAB17, member RAS oncogene family 2.58748
NOXO1 NADPH oxidase organizer 1 2.58748
ARSI arylsulfatase family, member I 2.58748
C3ORF22 chromosome 3 open reading frame 22 2.58748
TAS2R13 taste receptor, type 2, member 13 2.58748
PRDM16 PR domain containing 16 2.58748
GALR3 galanin receptor 3 2.58748
CPLX1 complexin 1 2.58748
SPX spexin hormone 2.58748
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.58748
NMUR1 neuromedin U receptor 1 2.58748
HIC1 hypermethylated in cancer 1 2.58748
HES2 hes family bHLH transcription factor 2 2.58748
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.58748
PDZD4 PDZ domain containing 4 2.58748
TMEM121 transmembrane protein 121 2.58748
KIF2A kinesin heavy chain member 2A 2.58748
GMFG glia maturation factor, gamma 2.58748
LCN10 lipocalin 10 2.58748
LCN15 lipocalin 15 2.58748
GLRA3 glycine receptor, alpha 3 2.58748
SLCO1B1 solute carrier organic anion transporter family, member 1B1 2.58748
KCNIP3 Kv channel interacting protein 3, calsenilin 2.58748
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.58748
GLIS1 GLIS family zinc finger 1 2.58748
OR7A17 olfactory receptor, family 7, subfamily A, member 17 2.58748
CPB2 carboxypeptidase B2 (plasma) 2.58748
SOST sclerostin 2.58748
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.58748
SPMAP2L sperm microtubule associated protein 2 like 2.58748
TMPRSS7 transmembrane protease, serine 7 2.58748
TSPAN1 tetraspanin 1 2.58748
CMKLR1 chemerin chemokine-like receptor 1 2.58748
MAGIX MAGI family member, X-linked 2.58748
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.58748
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.58748
CNTN6 contactin 6 2.58748
HNF1B HNF1 homeobox B 2.58748
STARD6 StAR-related lipid transfer (START) domain containing 6 2.58748
SAMD15 sterile alpha motif domain containing 15 2.58748
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 2.58748
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 2.58748
FRG2C FSHD region gene 2 family, member C 2.58748
TNS1-AS1 TNS1 antisense RNA 1 2.58748
C17ORF114 chromosome 17 open reading frame 114 2.58748
TMEM225B transmembrane protein 225B 2.58748
ATP5MGL ATP synthase membrane subunit g like 2.58748
CPHXL2 cytoplasmic polyadenylated homeobox like 2 2.58748
H1-6 H1.6 linker histone, cluster member 2.58748
SQOR sulfide quinone oxidoreductase 2.58748
LTB4R2 leukotriene B4 receptor 2 2.58748
MGAM maltase-glucoamylase 2.58748
DUSP8 dual specificity phosphatase 8 2.58748
PGLYRP2 peptidoglycan recognition protein 2 2.58748
CNTFR ciliary neurotrophic factor receptor 2.58748
ATP13A5 ATPase type 13A5 2.58748
ISM2 isthmin 2 2.58748
PRB1 proline-rich protein BstNI subfamily 1 2.58748
LOX lysyl oxidase 2.58748
SRPX2 sushi-repeat containing protein, X-linked 2 2.58748
GJA5 gap junction protein, alpha 5, 40kDa 2.58748
HLF hepatic leukemia factor 2.58748
HLX H2.0-like homeobox 2.58748
RNF17 ring finger protein 17 2.58748
UPK3A uroplakin 3A 2.58748
HDC histidine decarboxylase 2.58748
RAB41 RAB41, member RAS oncogene family 2.58748
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 2.58748
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.58748
INSRR insulin receptor-related receptor 2.58748
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 2.58748
MIA melanoma inhibitory activity 2.58748
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 2.58748
EDAR ectodysplasin A receptor 2.58748
ARL5C ADP-ribosylation factor-like 5C 2.58748
PRB2 proline-rich protein BstNI subfamily 2 2.58748
CDC7 cell division cycle 7 2.58748
IL15RA interleukin 15 receptor, alpha 2.58748
NR1H4 nuclear receptor subfamily 1, group H, member 4 2.58748
SHOX2 short stature homeobox 2 2.58748
SNX31 sorting nexin 31 2.58748
POU2AF1 POU class 2 associating factor 1 2.58748
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.58748
BAHCC1 BAH domain and coiled-coil containing 1 2.58748
CRHR1 corticotropin releasing hormone receptor 1 2.58748
SPATA45 spermatogenesis associated 45 2.58748
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.58748
COL17A1 collagen, type XVII, alpha 1 2.58748
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.58748
ZCCHC18 zinc finger, CCHC domain containing 18 2.58748
SFRP4 secreted frizzled-related protein 4 2.58748
CYS1 cystin 1 2.58748
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.58748
NXNL1 nucleoredoxin-like 1 2.58748
EXTL1 exostosin-like glycosyltransferase 1 2.58748
CST7 cystatin F (leukocystatin) 2.58748
EBLN1 endogenous Bornavirus-like nucleoprotein 1 2.58748
ADGRA1 adhesion G protein-coupled receptor A1 2.58748
FATE1 fetal and adult testis expressed 1 2.58748
CYSLTR1 cysteinyl leukotriene receptor 1 2.58748
OXSM 3-oxoacyl-ACP synthase, mitochondrial 2.58748
TBC1D10C TBC1 domain family, member 10C 2.58748
FBP1 fructose-1,6-bisphosphatase 1 2.58748
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.58748
ZNF843 zinc finger protein 843 2.58748
KLK8 kallikrein-related peptidase 8 2.58748
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.58748
SLC25A34 solute carrier family 25, member 34 2.58748
CLUL1 clusterin-like 1 (retinal) 2.58748
ABLIM3 actin binding LIM protein family, member 3 2.58748
PCDHAC1 protocadherin alpha subfamily C, 1 2.58748
ABI3 ABI family, member 3 2.58748
FKBP1C FK506 binding protein 1C 2.58748
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.58748
GSDMA gasdermin A 2.58748
SEZ6L seizure related 6 homolog (mouse)-like 2.58748
CFB complement factor B 2.58748
PFN4 profilin family, member 4 2.58748
CSDC2 cold shock domain containing C2, RNA binding 2.58748
KLK3 kallikrein-related peptidase 3 2.58748
PRPH peripherin 2.58748
EPHA10 EPH receptor A10 2.58748
ITGA11 integrin, alpha 11 2.58748
FGR FGR proto-oncogene, Src family tyrosine kinase 2.58748
ANKRD53 ankyrin repeat domain 53 2.58748
CAMSAP1 calmodulin regulated spectrin-associated protein 1 2.58748
PDCD1LG2 programmed cell death 1 ligand 2 2.58748
GPR62 G protein-coupled receptor 62 2.58748
DND1 DND microRNA-mediated repression inhibitor 1 2.58748
IFI35 interferon-induced protein 35 2.58748
ITGA8 integrin, alpha 8 2.58748
AHSG alpha-2-HS-glycoprotein 2.58748
ZBBX zinc finger, B-box domain containing 2.58748
SLITRK1 SLIT and NTRK-like family, member 1 2.58748
SLITRK6 SLIT and NTRK-like family, member 6 2.58748
POU3F2 POU class 3 homeobox 2 2.58748
NUTM2A NUT family member 2A 2.58748
PLGLB1 plasminogen-like B1 2.58748
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.58748
PRAM1 PML-RARA regulated adaptor molecule 1 2.58748
MST1 macrophage stimulating 1 2.58748
LPA lipoprotein, Lp(a) 2.58748
AQP1 aquaporin 1 (Colton blood group) 2.58748
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 2.58748
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 2.58748
TGM4 transglutaminase 4 2.58748
TGM1 transglutaminase 1 2.58748
ZNF404 zinc finger protein 404 2.58748
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 2.58748
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 2.58748
GRAP2 GRB2-related adaptor protein 2 2.58748
ANKRD33 ankyrin repeat domain 33 2.58748
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.58748
SPDEF SAM pointed domain containing ETS transcription factor 2.58748
APOD apolipoprotein D 2.58748
MAGEA2B melanoma antigen family A2B 2.58748
NGB neuroglobin 2.58748
FXYD2 FXYD domain containing ion transport regulator 2 2.58748
PITX3 paired-like homeodomain 3 2.58748
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 2.58748
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 2.58748
WNK4 WNK lysine deficient protein kinase 4 2.58748
LKAAEAR1 LKAAEAR motif containing 1 2.58748
CD177 CD177 molecule 2.58748
ICAM5 intercellular adhesion molecule 5, telencephalin 2.58748
TRIM29 tripartite motif containing 29 2.58748
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 2.57085
TDG thymine-DNA glycosylase 2.56589
EPSTI1 epithelial stromal interaction 1 (breast) 2.56385
IRX4 iroquois homeobox 4 2.55301
SYCP3 synaptonemal complex protein 3 2.55301
SLC37A3 solute carrier family 37, member 3 2.54757
MXRA5 matrix-remodelling associated 5 2.54757
TMEM141 transmembrane protein 141 2.54757
PHF20L1 PHD finger protein 20-like 1 2.54757
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 2.54757
SOCS5 suppressor of cytokine signaling 5 2.54757
TIPRL TOR signaling pathway regulator 2.5401
PON3 paraoxonase 3 2.52234
ATP11C ATPase, class VI, type 11C 2.50842
CSKMT citrate synthase lysine methyltransferase 2.44029
IGSF5 immunoglobulin superfamily, member 5 2.38705
SP2 Sp2 transcription factor 2.37448
VN1R1 vomeronasal 1 receptor 1 2.36037
TAS2R31 taste receptor, type 2, member 31 2.36037
TCHP trichoplein, keratin filament binding 2.36037
VIPR2 vasoactive intestinal peptide receptor 2 2.34426
NEB nebulin 2.3434
BTBD3 BTB (POZ) domain containing 3 2.32184
UBE2B ubiquitin-conjugating enzyme E2B 2.31204
CMSS1 cms1 ribosomal small subunit homolog (yeast) 2.30328
MSH3 mutS homolog 3 2.2602
SH3GL3 SH3-domain GRB2-like 3 2.25769
ATMIN ATM interactor 2.21477
TMEM242 transmembrane protein 242 2.20722
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.19355
TLK1 tousled-like kinase 1 2.19319
COX6C cytochrome c oxidase subunit VIc 2.1762
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 2.1762
GAS6 growth arrest-specific 6 2.17539
RNH1 ribonuclease/angiogenin inhibitor 1 2.16688
SLC35G2 solute carrier family 35, member G2 2.16552
ZCCHC2 zinc finger, CCHC domain containing 2 2.1645
ECSIT ECSIT signalling integrator 2.16394
TM9SF2 transmembrane 9 superfamily member 2 2.1071
TCEA1 transcription elongation factor A (SII), 1 2.09079
SLF2 SMC5-SMC6 complex localization factor 2 2.08992
GNG2 guanine nucleotide binding protein (G protein), gamma 2 2.08514
NXPH2 neurexophilin 2 2.04923
UBXN7 UBX domain protein 7 2.04825
MYO9B myosin IXB 2.04271
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 2.01661

decreased expression

Symbol Name Standardized Value
PIGV phosphatidylinositol glycan anchor biosynthesis, class V -2.58748
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 -2.58748
DXO decapping exoribonuclease -2.58748
GLB1L2 galactosidase, beta 1-like 2 -2.58748
COL4A2 collagen, type IV, alpha 2 -2.58748
TXK TXK tyrosine kinase -2.58748
MRPS2 mitochondrial ribosomal protein S2 -2.58748
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.58748
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -2.58748
RPS19 ribosomal protein S19 -2.58748
CCDC191 coiled-coil domain containing 191 -2.58748
N4BP2L1 NEDD4 binding protein 2-like 1 -2.58748
PAMR1 peptidase domain containing associated with muscle regeneration 1 -2.58748
SLC14A2 solute carrier family 14 (urea transporter), member 2 -2.58748
CCDC175 coiled-coil domain containing 175 -2.58748
CREBBP CREB binding protein -2.58748
ENO4 enolase family member 4 -2.58748
SLC67A1 solute carrier family 67 member 1 -2.58748
CCDC196 coiled-coil domain containing 196 -2.58748
PRSS35 protease, serine, 35 -2.58748
BCL3 B-cell CLL/lymphoma 3 -2.58748
THAP2 THAP domain containing, apoptosis associated protein 2 -2.58748
DSC3 desmocollin 3 -2.57802
TIMP2 TIMP metallopeptidase inhibitor 2 -2.56879
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.56385
SCPEP1 serine carboxypeptidase 1 -2.55301
CSPG4 chondroitin sulfate proteoglycan 4 -2.54757
GJA4 gap junction protein, alpha 4, 37kDa -2.54757
IL17REL interleukin 17 receptor E-like -2.54757
CPZ carboxypeptidase Z -2.54757
ACVR1C activin A receptor, type IC -2.54757
NPIPA7 nuclear pore complex interacting protein family, member A7 -2.54757
PANO1 proapoptotic nucleolar protein 1 -2.54757
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -2.54757
PSD4 pleckstrin and Sec7 domain containing 4 -2.54757
HAS1 hyaluronan synthase 1 -2.54757
FCRL5 Fc receptor-like 5 -2.54757
ANPEP alanyl (membrane) aminopeptidase -2.54757
RIMBP2 RIMS binding protein 2 -2.54757
ADCK5 aarF domain containing kinase 5 -2.54757
PLSCR2 phospholipid scramblase 2 -2.54757
NRIP2 nuclear receptor interacting protein 2 -2.54757
TMEM278 transmembrane protein 278 -2.54757
GPR34 G protein-coupled receptor 34 -2.54757
YPEL4 yippee-like 4 (Drosophila) -2.54757
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -2.54757
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -2.54757
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 -2.54757
PTGR3 prostaglandin reductase 3 -2.54757
CCDC177 coiled-coil domain containing 177 -2.54757
CCDC170 coiled-coil domain containing 170 -2.54757
CTSO cathepsin O -2.54757
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 -2.54757
DQX1 DEAQ box RNA-dependent ATPase 1 -2.54757
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -2.54757
PLCZ1 phospholipase C, zeta 1 -2.54757
IL19 interleukin 19 -2.54757
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -2.54757
HSPB6 heat shock protein, alpha-crystallin-related, B6 -2.54757
SFRP5 secreted frizzled-related protein 5 -2.54757
MPND MPN domain containing -2.5401
MAST3 microtubule associated serine/threonine kinase 3 -2.5401
LIAS lipoic acid synthetase -2.53718
BZW2 basic leucine zipper and W2 domains 2 -2.5155
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) -2.50842
ARTN artemin -2.4881
PDAP1 PDGFA associated protein 1 -2.48588
SMCO2 single-pass membrane protein with coiled-coil domains 2 -2.48523
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 -2.48523
LYPD3 LY6/PLAUR domain containing 3 -2.48523
CPNE4 copine IV -2.46558
PLSCR3 phospholipid scramblase 3 -2.45472
STX4 syntaxin 4 -2.45472
SHANK1 SH3 and multiple ankyrin repeat domains 1 -2.45472
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 -2.42082
SIAH1 siah E3 ubiquitin protein ligase 1 -2.40953
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -2.40887
MRPS5 mitochondrial ribosomal protein S5 -2.39345
TXNIP thioredoxin interacting protein -2.38348
WDR91 WD repeat domain 91 -2.38311
RNF220 ring finger protein 220 -2.35829
PLAC1 placenta-specific 1 -2.3434
SLC25A43 solute carrier family 25, member 43 -2.34178
DUSP23 dual specificity phosphatase 23 -2.34168
FBXL18 F-box and leucine-rich repeat protein 18 -2.32109
RNF167 ring finger protein 167 -2.31749
CYTL1 cytokine-like 1 -2.31711
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.31329
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.31329
CREB3L1 cAMP responsive element binding protein 3-like 1 -2.30683
SOX2 SRY (sex determining region Y)-box 2 -2.2874
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -2.28446
AGMO alkylglycerol monooxygenase -2.26768
HLA-C major histocompatibility complex, class I, C -2.2602
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit -2.25769
TMEM97 transmembrane protein 97 -2.24925
RDH10 retinol dehydrogenase 10 (all-trans) -2.24597
ZNF692 zinc finger protein 692 -2.21244
HSPB8 heat shock 22kDa protein 8 -2.21244
TMEM200C transmembrane protein 200C -2.21244
LOC122455342 testis-specific serine/proline-rich protein -2.20722
AKAP19 A-kinase anchoring protein 19 -2.19983
OLA1 Obg-like ATPase 1 -2.19351
UBXN1 UBX domain protein 1 -2.17539
FKBP1B FK506 binding protein 1B, 12.6 kDa -2.17525
DDR1 discoidin domain receptor tyrosine kinase 1 -2.16688
AVEN apoptosis, caspase activation inhibitor -2.16688
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) -2.16688
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.15795
METTL24 methyltransferase like 24 -2.11616
SCN1B sodium channel, voltage gated, type I beta subunit -2.11616
DIPK1A divergent protein kinase domain 1A -2.11488
ANAPC2 anaphase promoting complex subunit 2 -2.10021
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 -2.08549
ATAD3C ATPase family, AAA domain containing 3C -2.08549
SF3B4 splicing factor 3b, subunit 4, 49kDa -2.08549
C2ORF68 chromosome 2 open reading frame 68 -2.06892
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -2.04271
C8ORF33 chromosome 8 open reading frame 33 -2.04134
ANKFY1 ankyrin repeat and FYVE domain containing 1 -2.03983
TUG1 taurine up-regulated 1 (non-protein coding) -2.02215
YPEL5 yippee-like 5 (Drosophila) -2.01975