SU8686 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
Description Homo sapiens (human) pancreatic adenocarcinoma cell line. The line was developed from a wedge biosy of a liver metastasis of a pancreatic ductal carcinoma. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001904)
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Genes

377 gene knockdowns changing fitness of SU8686 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 3.19303
MPG N-methylpurine-DNA glycosylase 3.19
C10ORF2 chromosome 10 open reading frame 2 2.76226
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 2.26725
GPR27 G protein-coupled receptor 27 2.25954
PAX9 paired box 9 2.24438
BST2 bone marrow stromal cell antigen 2 2.21173
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 2.20949
OR1N2 olfactory receptor, family 1, subfamily N, member 2 2.08246
ZNF81 zinc finger protein 81 2.07222
LGI1 leucine-rich, glioma inactivated 1 2.03742
BRD2 bromodomain containing 2 2.01566
HEMK1 HemK methyltransferase family member 1 1.98727
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 1.93221
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 1.93196
HOXC5 homeobox C5 1.92075
CARD9 caspase recruitment domain family, member 9 1.8902
ALX4 ALX homeobox 4 1.88251
GPR32 G protein-coupled receptor 32 1.83239
SIAH3 siah E3 ubiquitin protein ligase family member 3 1.79895
RGS1 regulator of G-protein signaling 1 1.79667
MAST4 microtubule associated serine/threonine kinase family member 4 1.72629
HLA-DMB major histocompatibility complex, class II, DM beta 1.70584
SORCS2 sortilin-related VPS10 domain containing receptor 2 1.68622
MRPS28 mitochondrial ribosomal protein S28 1.65779
WDR11 WD repeat domain 11 1.65331
SORCS3 sortilin-related VPS10 domain containing receptor 3 1.65281
BDH2 3-hydroxybutyrate dehydrogenase, type 2 1.65221
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 1.64489
NPEPPS aminopeptidase puromycin sensitive 1.6133
NDN necdin, melanoma antigen (MAGE) family member 1.59151
OIT3 oncoprotein induced transcript 3 1.58888
TRPM2 transient receptor potential cation channel, subfamily M, member 2 1.55801
HNRNPL heterogeneous nuclear ribonucleoprotein L 1.55473
HESX1 HESX homeobox 1 1.54945
USP6 ubiquitin specific peptidase 6 1.54696
PLXNC1 plexin C1 1.54546
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.52284
PLAGL1 pleiomorphic adenoma gene-like 1 1.51604
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 1.48346
ETV1 ets variant 1 1.47439
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 1.47403
CDC25B cell division cycle 25B 1.47362
PAWR PRKC, apoptosis, WT1, regulator 1.45473
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 1.43312
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.43278
TIPRL TOR signaling pathway regulator 1.43217
STK32C serine/threonine kinase 32C 1.42006
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.41945
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 1.41087
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 1.40608
PARP16 poly (ADP-ribose) polymerase family, member 16 1.40452
ADAM22 ADAM metallopeptidase domain 22 1.40332
HIST1H3A histone cluster 1, H3a 1.40155
PPIH peptidylprolyl isomerase H (cyclophilin H) 1.40116
SP2 Sp2 transcription factor 1.4002
IFNA17 interferon, alpha 17 1.39646
EMX2 empty spiracles homeobox 2 1.39221
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.38927
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 1.38573
ARL1 ADP-ribosylation factor-like 1 1.38567
ULBP3 UL16 binding protein 3 1.38523
CBX2 chromobox homolog 2 1.38464
RIN2 Ras and Rab interactor 2 1.37658
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 1.37634
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 1.356
MRGPRD MAS-related GPR, member D 1.34943
TESK2 testis-specific kinase 2 1.34006
ZNF805 zinc finger protein 805 1.33093
FREM1 FRAS1 related extracellular matrix 1 1.32814
RGL4 ral guanine nucleotide dissociation stimulator-like 4 1.31283
SMS spermine synthase 1.30275
PCDHB10 protocadherin beta 10 1.29538
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.28421
DCP1A decapping mRNA 1A 1.28187
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 1.28098
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.26279
MAPKBP1 mitogen-activated protein kinase binding protein 1 1.26225
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 1.26224
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 1.2589
ZNF623 zinc finger protein 623 1.24502
NLK nemo-like kinase 1.24294
RAB19 RAB19, member RAS oncogene family 1.24121
ZNF333 zinc finger protein 333 1.23788
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 1.23673
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 1.23244
TRIM27 tripartite motif containing 27 1.23175
CCR8 chemokine (C-C motif) receptor 8 1.22859
SGK223 homolog of rat pragma of Rnd2 1.22539
MARK3 MAP/microtubule affinity-regulating kinase 3 1.21976
ACACA acetyl-CoA carboxylase alpha 1.21225
CRYBB2 crystallin, beta B2 1.21214
RREB1 ras responsive element binding protein 1 1.2109
MEN1 multiple endocrine neoplasia I 1.20769
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 1.19741
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 1.19008
GCM1 glial cells missing homolog 1 (Drosophila) 1.18809
NLGN1 neuroligin 1 1.18742
LTK leukocyte receptor tyrosine kinase 1.18211
MTFMT mitochondrial methionyl-tRNA formyltransferase 1.18194
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 1.17865
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 1.17323
MT3 metallothionein 3 1.16803
ANTXR1 anthrax toxin receptor 1 1.16431
GATAD2A GATA zinc finger domain containing 2A 1.15789
CCNC cyclin C 1.14965
GAK cyclin G associated kinase 1.14739
SNX29 sorting nexin 29 1.14448
PLXNB1 plexin B1 1.13436
ACSL6 acyl-CoA synthetase long-chain family member 6 1.12811
MYO1A myosin IA 1.12513
KRT85 keratin 85, type II 1.12343
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 1.12027
PNLIPRP1 pancreatic lipase-related protein 1 1.1192
TRPC3 transient receptor potential cation channel, subfamily C, member 3 1.11577
LOC652119 1.11518
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 1.11497
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 1.11251
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.10956
BAAT bile acid CoA:amino acid N-acyltransferase 1.1085
TGFB1I1 transforming growth factor beta 1 induced transcript 1 1.10703
GFPT2 glutamine-fructose-6-phosphate transaminase 2 1.09849
NQO1 NAD(P)H dehydrogenase, quinone 1 1.09409
AFF1 AF4/FMR2 family, member 1 1.09022
CALU calumenin 1.08966
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 1.08869
ZNF208 zinc finger protein 208 1.08868
FOXA1 forkhead box A1 1.08816
MRPL38 mitochondrial ribosomal protein L38 1.08716
ARG1 arginase 1 1.0871
POLRMT polymerase (RNA) mitochondrial (DNA directed) 1.08596
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 1.08511
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 1.0849
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.08428
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.08343
ELP4 elongator acetyltransferase complex subunit 4 1.08259
RIMS3 regulating synaptic membrane exocytosis 3 1.07778
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 1.07762
PRSS33 protease, serine, 33 1.07507
ZNF407 zinc finger protein 407 1.0744
FAM131B family with sequence similarity 131, member B 1.07225
PPIE peptidylprolyl isomerase E (cyclophilin E) 1.06828
STX5 syntaxin 5 1.06235
LPA lipoprotein, Lp(a) 1.06008
BRI3 brain protein I3 1.05728
MITF microphthalmia-associated transcription factor 1.05577
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.05311
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.05134
GMPR guanosine monophosphate reductase 1.04515
CTTN cortactin 1.04392
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.04028
NCAPD2 non-SMC condensin I complex, subunit D2 1.0373
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 1.03616
HMGN2 high mobility group nucleosomal binding domain 2 1.03606
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 1.03203
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.03097
FLT1 fms-related tyrosine kinase 1 1.02377
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.01843
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.01778
ZNF792 zinc finger protein 792 1.01735
HOXA10 homeobox A10 1.01705
LOC729739 peptidylprolyl isomerase A (cyclophilin A) pseudogene 1.01236
CDK13 cyclin-dependent kinase 13 1.00939
RAB1B RAB1B, member RAS oncogene family 1.00921
ZNF25 zinc finger protein 25 1.00785
LYPLA1 lysophospholipase I 1.00562
CXCR6 chemokine (C-X-C motif) receptor 6 1.00501

decreased fitness

Symbol Name Standardized Value
GPX3 glutathione peroxidase 3 -2.75989
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -2.66909
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -2.584
RBP4 retinol binding protein 4, plasma -2.58088
PI4KAP2 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2 -2.45744
RBMX RNA binding motif protein, X-linked -2.41716
SAMD4B sterile alpha motif domain containing 4B -2.41483
RACGAP1 Rac GTPase activating protein 1 -2.30519
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -2.19167
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.13172
RBMXL1 RNA binding motif protein, X-linked-like 1 -1.99723
ANTXR2 anthrax toxin receptor 2 -1.9534
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1 -1.92334
COL8A1 collagen, type VIII, alpha 1 -1.86287
DSTYK dual serine/threonine and tyrosine protein kinase -1.82361
DOCK5 dedicator of cytokinesis 5 -1.81544
ACOX1 acyl-CoA oxidase 1, palmitoyl -1.75012
ATRX alpha thalassemia/mental retardation syndrome X-linked -1.72655
FUBP1 far upstream element (FUSE) binding protein 1 -1.6936
RGS11 regulator of G-protein signaling 11 -1.68546
RHPN2 rhophilin, Rho GTPase binding protein 2 -1.68134
CPB2 carboxypeptidase B2 (plasma) -1.67927
PLSCR1 phospholipid scramblase 1 -1.64957
RIOK1 RIO kinase 1 -1.64933
ERCC6L excision repair cross-complementation group 6-like -1.63352
PMPCA peptidase (mitochondrial processing) alpha -1.62345
PEX3 peroxisomal biogenesis factor 3 -1.60968
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -1.59714
GPX6 glutathione peroxidase 6 -1.59292
TLR5 toll-like receptor 5 -1.58679
SREBF1 sterol regulatory element binding transcription factor 1 -1.57738
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -1.57342
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -1.57328
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -1.55517
NDUFC2-KCTD14 NDUFC2-KCTD14 readthrough -1.53628
LPPR1 lipid phosphate phosphatase-related protein type 1 -1.52459
KRAS Kirsten rat sarcoma viral oncogene homolog -1.52008
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -1.51569
MC5R melanocortin 5 receptor -1.5118
PAK1IP1 PAK1 interacting protein 1 -1.51171
GSK3A glycogen synthase kinase 3 alpha -1.50865
SMG6 SMG6 nonsense mediated mRNA decay factor -1.50443
CTSD cathepsin D -1.50373
NF1 neurofibromin 1 -1.50339
NONO non-POU domain containing, octamer-binding -1.46014
ZNF22 zinc finger protein 22 -1.45968
IL10 interleukin 10 -1.44133
PCCA propionyl CoA carboxylase, alpha polypeptide -1.43596
CD300C CD300c molecule -1.43302
RHOV ras homolog family member V -1.43112
TMPO thymopoietin -1.41919
SLC39A5 solute carrier family 39 (zinc transporter), member 5 -1.41837
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -1.41356
SCAP SREBF chaperone -1.41279
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) -1.40413
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -1.40074
TEX30 testis expressed 30 -1.39494
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -1.38066
FBXO21 F-box protein 21 -1.37995
WDR44 WD repeat domain 44 -1.36952
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -1.3666
ETFDH electron-transferring-flavoprotein dehydrogenase -1.36129
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -1.35699
ZNF8 zinc finger protein 8 -1.35062
KIF17 kinesin family member 17 -1.3498
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa -1.34917
MED4 mediator complex subunit 4 -1.34274
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -1.34111
DMBT1 deleted in malignant brain tumors 1 -1.31927
FAM207A family with sequence similarity 207, member A -1.31575
TAS2R14 taste receptor, type 2, member 14 -1.31377
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -1.31352
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -1.31185
PLEKHA5 pleckstrin homology domain containing, family A member 5 -1.30687
PAQR4 progestin and adipoQ receptor family member IV -1.30659
ABLIM3 actin binding LIM protein family, member 3 -1.30655
FCGBP Fc fragment of IgG binding protein -1.30578
NINJ2 ninjurin 2 -1.30568
DLG2 discs, large homolog 2 (Drosophila) -1.30168
SLA2 Src-like-adaptor 2 -1.29927
HIST1H3I histone cluster 1, H3i -1.29788
IGF2 insulin-like growth factor 2 -1.29765
ARHGAP24 Rho GTPase activating protein 24 -1.29712
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -1.29026
RAB34 RAB34, member RAS oncogene family -1.28692
SLC16A4 solute carrier family 16, member 4 -1.27991
PAQR6 progestin and adipoQ receptor family member VI -1.2794
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.27651
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 -1.2726
MCM3 minichromosome maintenance complex component 3 -1.26521
LONP1 lon peptidase 1, mitochondrial -1.26507
PAPL iron/zinc purple acid phosphatase-like protein -1.25649
CHD2 chromodomain helicase DNA binding protein 2 -1.25446
TCOF1 Treacher Collins-Franceschetti syndrome 1 -1.24784
TNPO3 transportin 3 -1.24734
ZNF45 zinc finger protein 45 -1.23967
TPR translocated promoter region, nuclear basket protein -1.23918
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 -1.23751
SF3A1 splicing factor 3a, subunit 1, 120kDa -1.23556
CD96 CD96 molecule -1.23331
UBE2I ubiquitin-conjugating enzyme E2I -1.22649
ALX3 ALX homeobox 3 -1.21677
STK32A serine/threonine kinase 32A -1.20712
TUBB tubulin, beta class I -1.20671
NKX2-2 NK2 homeobox 2 -1.20427
IK IK cytokine, down-regulator of HLA II -1.20309
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -1.19087
RPL23AP64 ribosomal protein L23a pseudogene 64 -1.18655
KISS1 KiSS-1 metastasis-suppressor -1.18624
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa -1.18025
FOXC1 forkhead box C1 -1.17985
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.17028
UBA1 ubiquitin-like modifier activating enzyme 1 -1.16238
SSX7 synovial sarcoma, X breakpoint 7 -1.16017
MATR3 matrin 3 -1.15997
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -1.1568
HNMT histamine N-methyltransferase -1.1566
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -1.15331
ZC3H13 zinc finger CCCH-type containing 13 -1.15242
PGP phosphoglycolate phosphatase -1.1515
NOG noggin -1.15102
FOXB1 forkhead box B1 -1.14838
CDCA8 cell division cycle associated 8 -1.14674
NFIB nuclear factor I/B -1.14639
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -1.14423
PHKG2 phosphorylase kinase, gamma 2 (testis) -1.14352
CHD8 chromodomain helicase DNA binding protein 8 -1.14156
OXSM 3-oxoacyl-ACP synthase, mitochondrial -1.13988
SCUBE3 signal peptide, CUB domain, EGF-like 3 -1.1392
PMPCB peptidase (mitochondrial processing) beta -1.13429
MCM6 minichromosome maintenance complex component 6 -1.12947
EPRS glutamyl-prolyl-tRNA synthetase -1.12852
DKC1 dyskeratosis congenita 1, dyskerin -1.12786
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -1.12536
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -1.12316
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -1.12314
EEF2 eukaryotic translation elongation factor 2 -1.1184
ZNF628 zinc finger protein 628 -1.11745
OR5AU1 olfactory receptor, family 5, subfamily AU, member 1 -1.11257
TXN thioredoxin -1.10931
ASPH aspartate beta-hydroxylase -1.10199
FGF22 fibroblast growth factor 22 -1.10188
BRAP BRCA1 associated protein -1.09959
TASP1 taspase, threonine aspartase, 1 -1.09853
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -1.09648
TXNL4A thioredoxin-like 4A -1.09528
PRKCZ protein kinase C, zeta -1.09132
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -1.08783
ARHGAP35 Rho GTPase activating protein 35 -1.08449
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -1.08396
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -1.08264
CD151 CD151 molecule (Raph blood group) -1.08188
C14ORF39 chromosome 14 open reading frame 39 -1.08181
PTPRC protein tyrosine phosphatase, receptor type, C -1.07434
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa -1.0743
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -1.07205
NUP93 nucleoporin 93kDa -1.07198
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 -1.07067
RNF146 ring finger protein 146 -1.07054
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -1.07012
ZNF197 zinc finger protein 197 -1.06855
SOD1 superoxide dismutase 1, soluble -1.0652
AQP3 aquaporin 3 (Gill blood group) -1.0623
ZNF230 zinc finger protein 230 -1.06201
NOXA1 NADPH oxidase activator 1 -1.06173
GPN3 GPN-loop GTPase 3 -1.05573
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -1.05538
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 -1.05435
ALG10B ALG10B, alpha-1,2-glucosyltransferase -1.05304
PRPF38B pre-mRNA processing factor 38B -1.05223
UBE2A ubiquitin-conjugating enzyme E2A -1.04321
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) -1.04081
NPTX2 neuronal pentraxin II -1.04013
NUP214 nucleoporin 214kDa -1.03901
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -1.03744
ZNF217 zinc finger protein 217 -1.03716
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -1.03713
MOGAT1 monoacylglycerol O-acyltransferase 1 -1.03646
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -1.02795
ZNF563 zinc finger protein 563 -1.02768
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1 -1.02753
MAP2K4 mitogen-activated protein kinase kinase 4 -1.0272
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -1.0269
SAE1 SUMO1 activating enzyme subunit 1 -1.02627
HPD 4-hydroxyphenylpyruvate dioxygenase -1.02593
MDFI MyoD family inhibitor -1.0256
SSX2B synovial sarcoma, X breakpoint 2B -1.02543
OR10A5 olfactory receptor, family 10, subfamily A, member 5 -1.02541
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -1.02496
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -1.02406
NR1H4 nuclear receptor subfamily 1, group H, member 4 -1.0231
EIF4A3 eukaryotic translation initiation factor 4A3 -1.02182
SMC1A structural maintenance of chromosomes 1A -1.02123
ELMO2 engulfment and cell motility 2 -1.02094
CASP6 caspase 6, apoptosis-related cysteine peptidase -1.01998
SLC14A2 solute carrier family 14 (urea transporter), member 2 -1.01803
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -1.01721
CFLAR CASP8 and FADD-like apoptosis regulator -1.01525
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 -1.01295
AP2M1 adaptor-related protein complex 2, mu 1 subunit -1.01133
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -1.01027
TOP2A topoisomerase (DNA) II alpha 170kDa -1.01022
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) -1.00992
PHB prohibitin -1.00918
RAB33A RAB33A, member RAS oncogene family -1.00706
IDS iduronate 2-sulfatase -1.00398
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -1.003
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 -1.00142
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.00032
SPINK4 serine peptidase inhibitor, Kazal type 4 -1.00013